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1. 发明申请

US20140248348A1 USE OF SALMONELLA FLAGELLIN DERIVATIVE IN PREPARATION OF DRUG FOR PREVENTING AND TREATING INFLAMMATORY BOWEL DISEASES 有权
标题翻译：用于制备药物以预防和治疗炎症性皮肤病的沙门氏菌白蛋白衍生物的应用
公开(公告)号：US20140248348A1
公开(公告)日：2014-09-04
申请号：US14131050
申请日：2012-01-19
申请人： Chenggang Zhang , Junhuai Li , Yang Xu , Yonghong Wu , Weiguang Li , Yanchun Zhang , Yan Gao , Zhihui Li
发明人： Chenggang Zhang , Junhuai Li , Yang Xu , Yonghong Wu , Weiguang Li , Yanchun Zhang , Yan Gao , Zhihui Li
IPC分类号： A61K38/16 , A61K9/28
CPC分类号： C07K14/255 , A61K9/2806 , A61K9/2893 , A61K38/00 , A61K38/164 , C07K2319/00 , Y02A50/473 , Y02A50/481
摘要： The application of flagellin derivative CZLC31 from Salmonella in preparation of medicines for preventing and treating inflammatory bowel disease (IBD) is introduced in this invention. The CZLC331 protein has a good preventive and therapeutic effect for IBD, such as ulcerative colitis (UC) and Crohn's disease (CD) in this invention. Therefore, this protein can be prepared into the drug for prevention and treatment of IBD. It has been found that the bad efficacy, slow onset, long course of treatment, side effects can be significantly avoided for existing clinical IBD drugs, it can reduce the patient's pain during the treatment in this invention. The rehabilitation and quality of life of the patients have been largely improved. The drug will play an important role in the prevention and treatment of IBD in this invention, and has broad application prospects.
摘要翻译：在本发明中引入了来自沙门氏菌的鞭毛蛋白衍生物CZLC31在制备用于预防和治疗炎症性肠病（IBD）的药物中的应用。本发明中CZLC331蛋白质对IBD具有良好的预防和治疗作用，如溃疡性结肠炎（UC）和克罗恩氏病（CD）。因此，该蛋白质可以制备成用于预防和治疗IBD的药物。已经发现，对于现有的临床IBD药物，可以显着避免功效差，缓慢发作，长期治疗，副作用，可以减轻本发明治疗期间患者的疼痛。患者的康复和生活质量已大大改善。该药物在本发明预防和治疗IBD中起着重要作用，具有广泛的应用前景。

2. 发明授权

US09259453B2 Use of salmonella flagellin derivative in preparation of drug for preventing and treating inflammatory bowel diseases 有权
标题翻译：使用沙门氏菌鞭毛蛋白衍生物制备用于预防和治疗炎症性肠病的药物
公开(公告)号：US09259453B2
公开(公告)日：2016-02-16
申请号：US14131050
申请日：2012-01-19
申请人： Chenggang Zhang , Junhuai Li , Yang Xu , Yonghong Wu , Weiguang Li , Yanchun Zhang , Yan Gao , Zhihui Li
发明人： Chenggang Zhang , Junhuai Li , Yang Xu , Yonghong Wu , Weiguang Li , Yanchun Zhang , Yan Gao , Zhihui Li
IPC分类号： C07K14/255 , A61K38/16 , A61K9/28
CPC分类号： C07K14/255 , A61K9/2806 , A61K9/2893 , A61K38/00 , A61K38/164 , C07K2319/00 , Y02A50/473 , Y02A50/481
摘要： The application of flagellin derivative CZLC31 from Salmonella in preparation of medicines for preventing and treating inflammatory bowel disease (IBD) is introduced in this invention. The CZLC331 protein has a good preventive and therapeutic effect for IBD, such as ulcerative colitis (UC) and Crohn's disease (CD) in this invention. Therefore, this protein can be prepared into the drug for prevention and treatment of IBD. It has been found that the bad efficacy, slow onset, long course of treatment, side effects can be significantly avoided for existing clinical IBD drugs, it can reduce the patient's pain during the treatment in this invention. The rehabilitation and quality of life of the patients have been largely improved. The drug will play an important role in the prevention and treatment of IBD in this invention, and has broad application prospects.
摘要翻译：在本发明中引入了来自沙门氏菌的鞭毛蛋白衍生物CZLC31在制备用于预防和治疗炎症性肠病（IBD）的药物中的应用。本发明中CZLC331蛋白质对IBD具有良好的预防和治疗作用，如溃疡性结肠炎（UC）和克罗恩氏病（CD）。因此，该蛋白质可以制备成用于预防和治疗IBD的药物。已经发现，对于现有的临床IBD药物，可以显着避免功效差，缓慢发作，长期治疗，副作用，可以减轻本发明治疗期间患者的疼痛。患者的康复和生活质量已大大改善。该药物在本发明预防和治疗IBD中起着重要作用，具有广泛的应用前景。

3. 外观设计

USD1045263S1 Cosmetic brush cleaning device 有权
公开(公告)号：USD1045263S1
公开(公告)日：2024-10-01
申请号：US29915197
申请日：2023-10-26
申请人： Yang Xu
设计人： Yang Xu
摘要： FIG. 1 is a front, top perspective view of a first embodiment of a cosmetic brush cleaning device, showing my new design;
FIG. 2 is a rear, bottom perspective view thereof;
FIG. 3 is a front elevation view thereof;
FIG. 4 is a rear elevation view thereof;
FIG. 5 is a left side elevation view thereof;
FIG. 6 is a right side elevation view thereof;
FIG. 7 is a top plan view thereof;
FIG. 8 is a bottom plan view thereof;
FIG. 9 is a front, top perspective view of a second embodiment of the cosmetic brush cleaning device;
FIG. 10 is a rear and bottom perspective view thereof;
FIG. 11 is a front view thereof;
FIG. 12 is a rear view thereof;
FIG. 13 is a left side view thereof;
FIG. 14 is a right side view thereof;
FIG. 15 is a top view thereof; and,
FIG. 16 is a bottom view thereof.
The broken lines in the figures illustrate portions of the cosmetic brush cleaning device that form no part of the claimed design.

4. 发明公开

US20240035014A1 TUNABLE NANOSCALE CAGES FROM SELF-ASSEMBLING DNA AND PROTEIN BUILDING BLOCKS 审中-公开
公开(公告)号：US20240035014A1
公开(公告)日：2024-02-01
申请号：US18485895
申请日：2023-10-12
申请人： Nicholas Stephanopoulos , Yang Xu
发明人： Nicholas Stephanopoulos , Yang Xu
IPC分类号： C12N9/88 , C07K19/00 , B82Y5/00 , C12N15/11
CPC分类号： C12N9/88 , C07K19/00 , C12Y401/02014 , B82Y5/00 , C12N15/11
摘要： Described herein are polyhedral, three-dimensional tunable nanocages assembled with a multimeric protein covalently linked to a polynucleotide handle and a DNA origami base assembly including sequences complementary to the polynucleotide handles, wherein the polynucleotide handle and the complementary sequences hybridize to for double-stranded DNA helices.

5. 发明授权

US10148253B2 Circuits for switched capacitor receiver front-ends 有权
公开(公告)号：US10148253B2
公开(公告)日：2018-12-04
申请号：US15573385
申请日：2016-05-11
申请人： Yang Xu , Peter R. Kinget
发明人： Yang Xu , Peter R. Kinget
IPC分类号： H03J3/08 , H03J5/24
摘要： Switched capacitor radio frequency receiver front-ends are provided, comprising: a plurality of banks, each comprising: a first switch connected to a RF input signal; a sampling capacitor connected to the first switch and to ground; a second switch connected in parallel to the sampling capacitor; and a Gm cell coupled to the sampling capacitor and an output; wherein: the output of the Gm cell of each of the plurality on banks are coupled together; and the first switch and the second switch are controlled by a multi-phase signal that causes, for each of the plurality of banks, the first switch to be turned ON at a first point in time and the second switch to be turned ON at a second point in time, wherein the first point in time for a first bank is not the same as the first point in time for a second bank.

6. 发明授权

US09927547B2 Power generating communication device 有权
公开(公告)号：US09927547B2
公开(公告)日：2018-03-27
申请号：US13773024
申请日：2013-02-21
申请人： Edward Wood , Zhiyue Xu , Yang Xu , David Gerrard
发明人： Edward Wood , Zhiyue Xu , Yang Xu , David Gerrard
IPC分类号： G01V3/20 , E21B47/12 , G01V11/00
CPC分类号： G01V3/20 , E21B47/12 , E21B47/121 , G01V11/002
摘要： A self-powered borehole communication assembly including a first electrode member having a first electrode potential and a second electrode member having a second electrode potential different than the first electrode potential. The first and second electrodes form an electrochemical cell when disposed in a borehole fluid that is at least partially electrolytic. The electrochemical cell is operatively arranged for producing a current and a voltage with at least one of the current or the voltage configured to directly convey information related to at least one borehole condition, property, or parameter. A method of communicating is also included.

7. 发明授权

US09188235B2 Plug counter, fracing system and method 有权
$Plug counter, fracing system and method$
标题翻译：插头计数器，边缘系统和方法
公开(公告)号：US09188235B2
公开(公告)日：2015-11-17
申请号：US14296674
申请日：2014-06-05
申请人： Yang Xu , Hector H. Mireles
发明人： Yang Xu , Hector H. Mireles
IPC分类号： E21B34/00 , F16K17/40 , E21B23/00 , E21B34/06 , E21B41/00 , E21B34/14 , F16K5/06
CPC分类号： F16K17/406 , E21B23/006 , E21B34/063 , E21B34/14 , E21B41/00 , E21B2034/002 , F16K5/0605 , Y10T137/1632 , Y10T137/3367
摘要： A valve includes a tubular having at least one port, and a sleeve in operable communication with the tubular configured to uncover the at least one port in response to moving from a first position to a second position. The valve also has a seat that is configured to be passed a selected number of times without shifting the sleeve from the first position to the second position and is further configured to be passed one additional time after the selected number of times after shifting the sleeve from the first position to the second position.
摘要翻译：阀包括具有至少一个端口的管状物，以及与所述管状物可操作地连通的套管，其构造成响应于从第一位置移动到第二位置而露出所述至少一个端口。阀还具有构造成经过选定次数的座椅，而不将套筒从第一位置移动到第二位置，并且还被构造成在将套筒从第一个位置到第二个位置。

8. 发明申请

US20150075639A1 PLUG COUNTER, FRACING SYSTEM AND METHOD 有权
标题翻译：插拔计数器，分离系统和方法
公开(公告)号：US20150075639A1
公开(公告)日：2015-03-19
申请号：US14296674
申请日：2014-06-05
申请人： Yang Xu , Hector H. Mireles
发明人： Yang Xu , Hector H. Mireles
IPC分类号： F16K17/40 , E21B34/14 , F16K5/06
CPC分类号： F16K17/406 , E21B23/006 , E21B34/063 , E21B34/14 , E21B41/00 , E21B2034/002 , F16K5/0605 , Y10T137/1632 , Y10T137/3367
摘要： A valve includes, a tubular having at least one port, a sleeve in operable communication with the tubular configured to uncover the at least one port in response to moving from a first position to a second position, and a seat that is configured to be passed a selected number of times without shifting the sleeve from the first position to the second position and is further configured to be passed one additional time after the selected number of times after shifting the sleeve from the first position to the second position.
摘要翻译：阀包括具有至少一个端口的管状物，与管状物可操作地连通的套管，其构造成响应于从第一位置移动到第二位置而露出所述至少一个端口，以及构造成通过选择次数，而不将套筒从第一位置移动到第二位置，并且还被配置为在将套筒从第一位置移动到第二位置之后经过选定次数之后经过一个额外的时间。

9. 发明授权

US08949293B2 Automatically matching data sets with storage components 有权
标题翻译：自动将数据集与存储组件进行匹配
公开(公告)号：US08949293B2
公开(公告)日：2015-02-03
申请号：US12972137
申请日：2010-12-17
申请人： Magdi A. Morsi , Wai Ho Au , Ying Sun , Sanjeev Katariya , Yang Xu , Nina Sarawgi
发明人： Magdi A. Morsi , Wai Ho Au , Ying Sun , Sanjeev Katariya , Yang Xu , Nina Sarawgi
IPC分类号： G06F17/30 , G06F11/34
CPC分类号： G06F17/30289 , G06F11/3442 , G06F11/3485
摘要： An administrator of an enterprise storage set may be tasked with storing a large number and variety of data sets on a large number and variety of storage components. However, the manual selection of a physical schema by an administrator may be time-consuming, may generate inefficient physical schemata, and may not be easily reevaluated as the data sets and storage set change. Presented herein are techniques for automatically determining a physical schema by comparing the storage factors of each data set (e.g., data size, relationships with other data sets, and usages of the data set by users) with the storage capabilities of the storage components, selecting a suitable storage component, and implementing the storage of the data set on the storage component. An embodiment of these techniques may thereby achieve an automated identification of a physical schema with improved efficiency and flexibility of the physical schema while conserving administrative resources.
摘要翻译：企业存储集的管理员可以负责在大量和多种存储组件上存储大量和多种数据集。然而，由管理员手动选择物理模式可能是耗时的，可能产生低效的物理模式，并且可能不会随数据集和存储集改变而容易地重新评估。这里提出的技术是通过将每个数据集的存储因子（例如，数据大小，与其他数据集的关系以及用户的数据集的使用）与存储组件的存储能力进行比较来自动确定物理模式，选择合适的存储组件，以及在存储组件上实现数据集的存储。因此，这些技术的实施例可以实现物理模式的自动识别，同时节省管理资源，同时提高物理模式的效率和灵活性。

10. 发明授权

US08938454B2 Using a tunable finite automaton for regular expression matching 有权
标题翻译：使用可调谐有限自动机进行正则表达式匹配
公开(公告)号：US08938454B2
公开(公告)日：2015-01-20
申请号：US13648438
申请日：2012-10-10
申请人： H. Jonathan Chao , Yang Xu
发明人： H. Jonathan Chao , Yang Xu
IPC分类号： G06F7/00 , G06F17/30
CPC分类号： G06F17/30985
摘要： Deterministic Finite Automatons (DFAs) and Nondeterministic Finite Automatons (NFAs) are two typical automatons used in the Network Intrusion Detection System (NIDS). Although they both perform regular expression matching, they have quite different performance and memory usage properties. DFAs provide fast and deterministic matching performance but suffer from the well-known state explosion problem. NFAs are compact, but their matching performance is unpredictable and with no worst case guarantee. A new automaton representation of regular expressions, called Tunable Finite Automaton (TFA), is described. TFAs resolve the DFAs' state explosion problem and the NFAs' unpredictable performance problem. Different from a DFA, which has only one active state, a TFA allows multiple concurrent active states. Thus, the total number of states required by the TFA to track the matching status is much smaller than that required by the DFA. Different from an NFA, a TFA guarantees that the number of concurrent active states is bounded by a bound factor b that can be tuned during the construction of the TFA according to the needs of the application for speed and storage. A TFA can achieve significant reductions in the number of states and memory space.
摘要翻译：确定性有限自动机（DFA）和非确定性有限自动机（NFAs）是网络入侵检测系统（NIDS）中使用的两种典型自动机。虽然它们都执行正则表达式匹配，但它们具有非常不同的性能和内存使用属性。 DFA提供快速和确定性的匹配性能，但遭受着名的国家爆炸问题。 NFAs是紧凑的，但它们的匹配性能是不可预测的，没有最坏的情况保证。描述了称为可调谐有限自动机（TFA）的正则表达式的新自动机表示。 TFAs解决了DFA的状态爆炸问题和NFAs不可预测的性能问题。与仅具有一个活动状态的DFA不同，TFA允许多个并发活动状态。因此，TFA跟踪匹配状态所需的状态总数远远小于DFA所要求的状态总数。与NFA不同，TFA保证并行活动状态的数量受绑定因子b的约束，根据应用速度和存储的需要，可以在构建TFA期间进行调整。 TFA可以显着减少状态和记忆空间的数量。

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