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1. 发明申请

US20090036844A1 Reservoir with liquidly applied seal 审中-公开
标题翻译：水库带有液体密封
公开(公告)号：US20090036844A1
公开(公告)日：2009-02-05
申请号：US11628293
申请日：2005-05-31
申请人： Charlotte Juel Fristrup , Lasse Hansen
发明人： Charlotte Juel Fristrup , Lasse Hansen
IPC分类号： A61M31/00 , A61J1/10 , B05D3/00 , A61J1/14
CPC分类号： A61J1/1406 , A61J1/10 , A61J1/1475
摘要： The present invention provides a fluid reservoir comprising a first wall portion formed from a needle-penetrable material, the first wall portion comprising a seal surface. The reservoir further comprises a seal member formed from a needle-penetratable self-sealing material, wherein the seal member has been applied on the seal surface in a liquid state. In this way a liquid reservoir having a self-sealing needle-penetrable access means which can be manufactured in a cost-effective manner is provided.
摘要翻译：本发明提供了一种流体储存器，其包括由可穿透针材料形成的第一壁部分，第一壁部分包括密封表面。储存器还包括由可穿透针的自密封材料形成的密封构件，其中密封构件已经以液体状态施加在密封表面上。以这种方式，提供了一种具有能够以经济有效的方式制造的自密封针穿透进入装置的液体储存器。

2. 发明申请

US20090036867A1 Medication Delivery Device Applying A Collapsible Reservoir 审中-公开
标题翻译：药物输送装置应用可折叠水库
公开(公告)号：US20090036867A1
公开(公告)日：2009-02-05
申请号：US12159799
申请日：2007-01-05
申请人： Kristian Glejboel , Frank Daniel Mersebach , Michael Hansen Svendsmark , Niels-Aage Hansen , Lasse Hansen
发明人： Kristian Glejboel , Frank Daniel Mersebach , Michael Hansen Svendsmark , Niels-Aage Hansen , Lasse Hansen
IPC分类号： A61M5/20
CPC分类号： A61M5/14216 , A61M5/14244 , A61M5/16809 , A61M5/172
摘要： The present invention relates to a medication delivery device comprising pump means and a reservoir adapted for containing a medicament. The pump means is adapted to transfer the medicament from the reservoir to an outlet arrangement, said outlet arrangement being adapted to be operatively connected to an associated hypodermic needle. The pumps means is adapted to deliver a set dose of medicament during one or more pump strokes, wherein the stroke volume(s) of said one or more pump strokes is variable. The present invention further relates to a method for adjusting stroke volumes to a set dose of medicament.
摘要翻译：本发明涉及药物输送装置，其包括泵装置和适于容纳药物的贮存器。泵装置适于将药物从储存器转移到出口装置，所述出口装置适于可操作地连接到相关联的皮下注射针。泵装置适于在一个或多个泵冲程期间递送一定剂量的药物，其中所述一个或多个泵冲程的冲程容积是可变的。本发明还涉及一种用于调整针对一定剂量的药物的卒中体积的方法。

3. 发明申请

US20080311321A1 Multilayer Film With Septum Layer 审中-公开
标题翻译：多层膜与隔垫层
公开(公告)号：US20080311321A1
公开(公告)日：2008-12-18
申请号：US11917202
申请日：2006-06-21
申请人： Philip Albert Sparholt , Lasse Hansen
发明人： Philip Albert Sparholt , Lasse Hansen
IPC分类号： B32B25/08
CPC分类号： B32B27/08 , A61J1/00 , A61J1/1406 , B32B7/02 , B32B7/12 , B32B25/08 , B32B25/20 , B32B27/302 , B32B27/32 , B32B27/322 , B32B27/34 , B32B27/36 , B32B27/40 , B32B2309/105 , B32B2439/80 , Y10T428/1334 , Y10T428/266 , Y10T428/2817 , Y10T428/2826
摘要： A flexible multilayer film for forming a container defining a liquid-tight chamber for storing a liquid is described here. The film comprises a first layer (1) and a second layer (2). The first layer (1) is a barrier layer, for example, a PCTFE layer, which is arranged inwardly of the second layer (2) as seen in a direction from the chamber of the container formed from the multilayer film. The second layer (2) is a septum layer, for example, a TPE layer, having self-sealing properties so as to seal around a hypodermic needle penetrating said film. As seen in the above direction an innermost surface (5) of the film is weldable onto itself and is preferably made of a weldable layer (3) comprising PE and/or PP.
摘要翻译：这里描述了用于形成限定用于储存液体的液密室的容器的柔性多层膜。膜包括第一层（1）和第二层（2）。第一层（1）是从从多层膜形成的容器的室的方向观察时，设置在第二层（2）的内侧的阻挡层，例如PCTFE层。第二层（2）是隔膜层，例如具有自密封性质的TPE层，以便围绕穿透所述膜的皮下注射针密封。从上述方向可以看出，膜的最内表面（5）可焊接在其自身上，并且优选由包含PE和/或PP的可焊接层（3）制成。

4. 发明授权

US07972558B2 Method and an apparatus for sterilizing packaging material 失效
标题翻译：包装材料灭菌方法及装置
公开(公告)号：US07972558B2
公开(公告)日：2011-07-05
申请号：US12280689
申请日：2007-02-28
申请人： Lasse Hansen , Anders Dossing Norskov , Per Jeppensen , Signe Agnete Christensen
发明人： Lasse Hansen , Anders Dossing Norskov , Per Jeppensen , Signe Agnete Christensen
IPC分类号： A61L2/00 , B01J19/00 , B65B31/00 , B65B29/00 , B65B55/02 , A45C11/04 , A61B17/06 , G01N21/01 , G01N23/00 , A21D10/02 , A23L3/00 , B65D85/84
CPC分类号： B65B55/08 , A61L2/0011 , A61L2/0035 , A61L2/081 , A61L2/085 , A61L2/087 , A61L2/10 , A61L2/24 , A61L2202/122 , Y10S206/828
摘要： A method and an apparatus for sterilizing packaging material for use in packaging for protein containing products, such as food products or medical drugs. The packaging material is sterilized by irradiating it using a beam of ionizing radiation, such as an electron beam or a beam of gamma rays. Afterwards, the packaging material is processed in such a manner that protein reactive substances or compounds formed in the packaging material during the irradiation step are at least partly removed or rendered inreactive with respect to proteins. The processing step may advantageously be performed by heating the packaging material. Preferably, the processing step involves accelerating diffusion from the packaging material of protein reactive substances or compounds. Since the protein reactive substances or compounds are removed or rendered inreactive with respect to proteins, degradation of the product which is later stored in the packaging material is considerably reduced. The packaging material needs to be stored under sterile conditions for a shorter period of time. Thereby the space needed for sterile storage, as well of the risk of contamination, is considerably reduced.
摘要翻译：一种用于消毒用于包装蛋白质的产品如食品或医药的包装材料的方法和装置。通过使用诸如电子束或伽马射线的电离辐射束照射包装材料来消毒包装材料。之后，将包装材料加工成使得在照射步骤期间在包装材料中形成的蛋白质反应性物质或化合物至少部分地被去除或对蛋白质具有反应性。加工步骤可有利地通过加热包装材料来进行。优选地，加工步骤包括加速来自蛋白质反应性物质或化合物的包装材料的扩散。由于蛋白质反应性物质或化合物相对于蛋白质被去除或呈现反应性，所以后来储存在包装材料中的产品的降解会大大降低。包装材料需要在无菌条件下储存较短的时间。因此，无菌储存所需的空间以及污染风险大大降低。

5. 发明申请

US20090148340A1 METHOD AND AN APPARATUS FOR STERILIZING PACKAGING MATERIAL 失效
标题翻译：用于灭菌包装材料的方法和装置
公开(公告)号：US20090148340A1
公开(公告)日：2009-06-11
申请号：US12280689
申请日：2007-02-28
申请人： Lasse Hansen , Anders Dossing , Per Jeppesen , Signe Agnete Christensen
发明人： Lasse Hansen , Anders Dossing , Per Jeppesen , Signe Agnete Christensen
IPC分类号： A61L2/08 , G01N23/00
CPC分类号： B65B55/08 , A61L2/0011 , A61L2/0035 , A61L2/081 , A61L2/085 , A61L2/087 , A61L2/10 , A61L2/24 , A61L2202/122 , Y10S206/828
摘要： A method and an apparatus for sterilizing packaging material for use in packaging for protein containing products, such as food products or medical drugs. The packaging material is sterilized by irradiating it using a beam of ionizing radiation, such as an electron beam or a beam of gamma rays. Afterwards, the packaging material is processed in such a manner that protein reactive substances or compounds formed in the packaging material during the irradiation step are at least partly removed or rendered inreactive with respect to proteins. The processing step may advantageously be performed by heating the packaging material. Preferably, the processing step involves accelerating diffusion from the packaging material of protein reactive substances or compounds. Since the protein reactive substances or compounds are removed or rendered inreactive with respect to proteins, degradation of the product which is later stored in the packaging material is considerably reduced. The packaging material needs to be stored under sterile conditions for a shorter period of time. Thereby the space needed for sterile storage, as well of the risk of contamination, is considerably reduced.
摘要翻译：一种用于消毒用于包装蛋白质的产品如食品或医药的包装材料的方法和装置。通过使用诸如电子束或伽马射线的电离辐射束照射包装材料来消毒包装材料。之后，将包装材料加工成使得在照射步骤期间在包装材料中形成的蛋白质反应性物质或化合物至少部分地被去除或对蛋白质具有反应性。加工步骤可有利地通过加热包装材料来进行。优选地，加工步骤包括加速来自蛋白质反应性物质或化合物的包装材料的扩散。由于蛋白质反应性物质或化合物相对于蛋白质被去除或呈现反应性，所以后来储存在包装材料中的产品的降解会大大降低。包装材料需要在无菌条件下储存较短的时间。因此，无菌储存所需的空间以及污染风险大大降低。

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