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1. 发明授权

US08222280B2 Ether compounds with nitrogen-containing 5-member heterocycle and uses thereof 有权
标题翻译：具有含氮5元杂环的醚化合物及其用途
公开(公告)号：US08222280B2
公开(公告)日：2012-07-17
申请号：US13121334
申请日：2009-11-25
申请人： Changling Liu , Miao Li , Junfeng Wang , Jinbo Zhang , Hong Zhang , Shulin Hao , Jing Zhang , Jichun Yang
发明人： Changling Liu , Miao Li , Junfeng Wang , Jinbo Zhang , Hong Zhang , Shulin Hao , Jing Zhang , Jichun Yang
IPC分类号： A61K31/44 , A61K31/427 , A61K31/415 , C07D401/02 , C07D277/20 , C07D231/10
CPC分类号： C07D231/12 , A01N43/56 , A01N43/80 , C07D401/04 , C07D407/04 , C07D409/04 , C07D417/04
摘要： The invention relates to ether compounds with nitrogen-containing 5-member heterocycle, represented by formula (I): The groups are as defined as specification.The compounds of the present invention have broad-spectrum insecticidal activities, and they are very effective to lepidopterous pests, including Ostrinia nubilalis, sugarcane borer, summer fruit tortrix moth, Grapholitha inopinata, Lymantria dispar, Cnaphalocrocis medialis, Pyrausta nubilalis, Heliothis assulta, Grapholitha molesta, Plutella xylostella, Laphygma exigua, Prodenialitura and the like, especially more effective to Plutella xylostella and Laphygma exigua, and can have very good effects at very low doses. And the compounds of present invention have high activities to homopteran pests such as aphid. At the same time, some compounds of present invention have very good fungicidal activities, and can be used for preventing wheat powdery mildew, cucumber downy mildew, vegetable grey mould and the like.
摘要翻译：本发明涉及具有式（I）表示的含氮的5-元杂环的醚化合物：这些基团如规定所定义。本发明化合物具有广谱杀虫活性，对鳞翅目害虫非常有效，其中包括鸵鸟，甘蔗螟，夏季果蝇蛾，，，ata disp disp disp disp，，is is，，，a a a a a a a a a a a a a a a a a a a a 禾本小菜，小菜蛾，小菜蛾等，对小菜蛾和小菜蛾特别有效，在非常低的剂量下具有非常好的效果。本发明化合物对同翅目害虫如蚜虫具有高活性。同时，本发明的一些化合物具有非常好的杀真菌活性，可用于预防小麦白粉病，黄瓜霜霉病，植物灰霉病等。

2. 发明申请

US20110046152A1 Amide Compounds, Preparation Methods and Uses Thereof 有权
标题翻译：酰胺化合物，其制备方法和用途
公开(公告)号：US20110046152A1
公开(公告)日：2011-02-24
申请号：US12990194
申请日：2009-06-03
申请人： Changling Liu , Baoshan Chai , Hong Zhang , Jichun Yang , Zhinian Li , Yongwu Peng , Junfeng Wang , Jiao Wu , Shicun Ma , Miao Li
发明人： Changling Liu , Baoshan Chai , Hong Zhang , Jichun Yang , Zhinian Li , Yongwu Peng , Junfeng Wang , Jiao Wu , Shicun Ma , Miao Li
IPC分类号： A01N43/60 , C07D401/14 , A01N43/56 , C07D213/74 , A01N43/40 , A01P3/00 , A01P7/04
CPC分类号： A01N43/60 , A01N43/56 , A01N53/00 , C07D211/04 , C07D213/74 , C07D231/10 , C07D237/06 , C07D239/24 , C07D401/14 , C07D403/12 , C07D403/14
摘要： Amide compounds, preparation methods and uses thereof. The structure of the compounds is represented as the general formula (I), in which the definitions of substituents are illuminated as description. The present amide compounds have broad spectrum activity of killing pests and are effective on lepidopteran pests including ostrinia nubilalis, sugarcane borer, adoxophyes orana fischer von reslerstamm, apple fruit borer, grapholitha inopinata, lymantri dispar l., cnaphalocrocis medinalis, ostrinia furnacalis, helicoverpa assulta, grapholitha inopinata, plutella xylostella, spodoptera exigua, prodenia litura etc., especially for plutella xylostella, spodoptera exigua. The present amide compounds can obtain good effect at very low dosage. At the same time, some compounds have good fungicidal activity which can be used to prevent rice blast, phytophthora infestans, cucumber downy mildew or grey mould of vegetables.
摘要翻译：酰胺化合物，其制备方法和用途。化合物的结构表示为通式（I），其中取代基的定义被描述为照亮。本发明的酰胺化合物具有杀虫害虫的广谱活性，对鳞翅目害虫有效，包括鸵鸟，甘蔗螟，苹果果螟，，，ata ata ata，，，，disp disp disp a a a a a a a a a a a a a a a a a ，鹅掌楸，小菜蛾，草地贪夜蛾，小蠊等，特别是小菜蛾，草地贪夜蛾。本发明的酰胺化合物可以在非常低的剂量下获得良好的效果。同时，一些化合物具有良好的杀真菌活性，可用于预防稻瘟病，致病疫霉，黄瓜霜霉病或蔬菜灰霉病。

3. 发明授权

US08455398B2 Amide compounds, preparation methods and uses thereof 有权
标题翻译：酰胺化合物，其制备方法和用途
公开(公告)号：US08455398B2
公开(公告)日：2013-06-04
申请号：US12990194
申请日：2009-06-03
申请人： Changling Liu , Baoshan Chai , Hong Zhang , Jichun Yang , Zhinian Li , Yongwu Peng , Junfeng Wang , Jiao Wu , Shicun Ma , Miao Li
发明人： Changling Liu , Baoshan Chai , Hong Zhang , Jichun Yang , Zhinian Li , Yongwu Peng , Junfeng Wang , Jiao Wu , Shicun Ma , Miao Li
IPC分类号： A01N43/40 , A01N43/50 , C07D213/72 , C07D401/14 , C07D401/02
CPC分类号： A01N43/60 , A01N43/56 , A01N53/00 , C07D211/04 , C07D213/74 , C07D231/10 , C07D237/06 , C07D239/24 , C07D401/14 , C07D403/12 , C07D403/14
摘要： Amide compounds, preparation methods and uses thereof. The structure of the compounds is represented as the general formula (I), in which the definitions of substituents are illuminated as description. The present amide compounds have broad spectrum activity of killing pests and are effective on lepidopteran pests including ostrinia nubilalis, sugarcane borer, adoxophyes orana fischer von reslerstamm, apple fruit borer, grapholitha inopinata, lymantri dispar l., cnaphalocrocis medinalis, ostrinia furnacalis, helicoverpa assulta, grapholitha inopinata, plutella xylostella, spodoptera exigua, prodenia litura etc., especially for plutella xylostella, spodoptera exigua. The present amide compounds can obtain good effect at very low dosage. At the same time, some compounds have good fungicidal activity which can be used to prevent rice blast, phytophthora infestans, cucumber downy mildew or grey mold of vegetables.
摘要翻译：酰胺化合物，其制备方法和用途。化合物的结构表示为通式（I），其中取代基的定义被描述为照亮。本发明的酰胺化合物具有杀虫害虫的广谱活性，对鳞翅目害虫有效，包括鸵鸟，甘蔗螟，苹果果螟，，，ata ata ata，，，，disp disp disp a a a a a a a a a a a a a a a a a ，鹅掌楸，小菜蛾，草地贪夜蛾，小蠊等，特别是小菜蛾，草地贪夜蛾。本发明的酰胺化合物可以在非常低的剂量下获得良好的效果。同时，一些化合物具有良好的杀真菌活性，可用于预防稻瘟病，致病疫霉，黄瓜霜霉病或蔬菜灰霉病。

4. 发明申请

US20100113490A1 Substituted Pyrimidine Ether Compounds and use thereof 有权
标题翻译：取代的嘧啶醚化合物及其用途
公开(公告)号：US20100113490A1
公开(公告)日：2010-05-06
申请号：US12597173
申请日：2008-05-22
申请人： Changling Liu , Baoshan Chai , Hong Zhang , Huichao Li , Junfeng Wang , Yongwu Peng , Jichun Yang , Guangxin Liu , Zhinian Li
发明人： Changling Liu , Baoshan Chai , Hong Zhang , Huichao Li , Junfeng Wang , Yongwu Peng , Jichun Yang , Guangxin Liu , Zhinian Li
IPC分类号： A01N43/54 , C07D239/47 , A01P3/00 , A01P7/02 , A01P7/04
CPC分类号： A01N43/54 , A01N43/56 , A01N43/78 , A01N47/24 , C07D239/47
摘要： The invention relates to substituted pyrimidine ether compounds having general formula I: The groups are as defined as specification.The compounds of formula I show high insecticidal activities for imagoes, larvae and nits of harmful acari and insects in the agricultural, civil and zoic fields, especially show excellent insecticidal activities for harmful acari such as Tetranychus cinnabarinus. Good effects can be obtained at very low dose. The compounds also exhibit preferably fungicidal activity. Wherefore, the invention also comprises the uses of compounds of formula I as insecticides, acaricides and/or fungicides in agricultural and other fields.
摘要翻译：本发明涉及具有通式I的取代的嘧啶醚化合物：这些基团如规定所定义。式I化合物在农业，民用和盐酸领域中对于成虫，幼虫和有害螨虫和昆虫的蚊子具有很高的杀虫活性，特别是对有害猕猴桃（Tetranychus cinnabarinus）具有极好的杀虫活性。在非常低的剂量下可以获得良好的效果。所述化合物还优选具有杀真菌活性。因此，本发明还包括在农业和其他领域中式I化合物作为杀虫剂，杀螨剂和/或杀真菌剂的用途。

5. 发明授权

US08383640B2 Substituted pyrimidine ether compounds and use thereof 有权
标题翻译：取代的嘧啶醚化合物及其用途
公开(公告)号：US08383640B2
公开(公告)日：2013-02-26
申请号：US12597173
申请日：2008-05-22
申请人： Changling Liu , Baoshan Chai , Hong Zhang , Huichao Li , Junfeng Wang , Yongwu Peng , Jichun Yang , Guangxin Liu , Zhinian Li
发明人： Changling Liu , Baoshan Chai , Hong Zhang , Huichao Li , Junfeng Wang , Yongwu Peng , Jichun Yang , Guangxin Liu , Zhinian Li
IPC分类号： A61K31/505
CPC分类号： A01N43/54 , A01N43/56 , A01N43/78 , A01N47/24 , C07D239/47
摘要： The invention relates to substituted pyrimidine ether compounds having general formula I: The groups are as defined as specification.The compounds of formula I show high insecticidal activities for imagoes, larvae and nits of harmful acari and insects in the agricultural, civil and zoic fields, especially show excellent insecticidal activities for harmful acari such as Tetranychus cinnabarinus. Good effects can be obtained at very low dose. The compounds also exhibit preferably fungicidal activity. Wherefore, the invention also comprises the uses of compounds of formula I as insecticides, acaricides and/or fungicides in agricultural and other fields.
摘要翻译：本发明涉及具有通式I的取代的嘧啶醚化合物：这些基团如规定所定义。式I化合物在农业，民用和盐酸领域中对于成虫，幼虫和有害螨虫和昆虫的蚊子具有很高的杀虫活性，特别是对有害猕猴桃（Tetranychus cinnabarinus）具有极好的杀虫活性。在非常低的剂量下可以获得良好的效果。所述化合物还优选具有杀真菌活性。因此，本发明还包括在农业和其他领域中式I化合物作为杀虫剂，杀螨剂和/或杀真菌剂的用途。

6. 发明申请

US20110178149A1 Ether Compounds with Nitrogen-Containing 5-Member Heterocycle and Uses Thereof 有权
标题翻译：具有含氮5元杂环的醚化合物及其用途
公开(公告)号：US20110178149A1
公开(公告)日：2011-07-21
申请号：US13121334
申请日：2009-11-25
申请人： Changling Liu , Miao Li , Junfeng Wang , Jinbo Zhang
发明人： Changling Liu , Miao Li , Junfeng Wang , Jinbo Zhang
IPC分类号： A01N43/56 , C07D231/18 , A01P3/00 , A01P7/04
CPC分类号： C07D231/12 , A01N43/56 , A01N43/80 , C07D401/04 , C07D407/04 , C07D409/04 , C07D417/04
摘要： The invention relates to ether compounds with nitrogen-containing 5-member heterocycle, represented by formula (I): The groups are as defined as specification.The compounds of the present invention have broad-spectrum insecticidal activities, and they are very effective to lepidopterous pests, including Ostrinia nubilalis, sugarcane borer, summer fruit tortrix moth, Grapholitha inopinata, Lymantria dispar, Cnaphalocrocis medialis, Pyrausta nubilalis, Heliothis assulta, Grapholitha molesta, Plutella xylostella, Laphygma exigua, Prodenialitura and the like, especially more effective to Plutella xylostella and Laphygma exigua, and can have very good effects at very low doses. And the compounds of present invention have high activities to homopteran pests such as aphid. At the same time, some compounds of present invention have very good fungicidal activities, and can be used for preventing wheat powdery mildew, cucumber downy mildew, vegetable grey mould and the like.
摘要翻译：本发明涉及具有式（I）表示的含氮的5-元杂环的醚化合物：这些基团如规定所定义。本发明化合物具有广谱杀虫活性，对鳞翅目害虫非常有效，其中包括鸵鸟，甘蔗螟，夏季果蝇蛾，，，ata disp disp disp disp，，is is，，，a a a a a a a a a a a a a a a a a a a a 禾本小菜，小菜蛾，小菜蛾等，对小菜蛾和小菜蛾特别有效，在非常低的剂量下具有非常好的效果。本发明化合物对同翅目害虫如蚜虫具有高活性。同时，本发明的一些化合物具有非常好的杀真菌活性，可用于预防小麦白粉病，黄瓜霜霉病，植物灰霉病等。

7. 发明申请

US20110046186A1 1-Substituted Pyridyl-Pyrazolyl Amide Compounds and Uses Thereof 有权
标题翻译： 1-取代的吡啶基 - 吡唑基酰胺化合物及其用途
公开(公告)号：US20110046186A1
公开(公告)日：2011-02-24
申请号：US12990193
申请日：2009-07-03
申请人： Bin Li , Huibin Yang , Junfeng Wang , Haibo Yu , Hong Zhang , Zhinian Li , Yuquan Song
发明人： Bin Li , Huibin Yang , Junfeng Wang , Haibo Yu , Hong Zhang , Zhinian Li , Yuquan Song
IPC分类号： A01N43/56 , C07D401/04 , A01P3/00 , A01P7/04
CPC分类号： C07D401/04 , A01N43/56
摘要： The present invention discoses a kind of 1-substituted pyridyl-pyrazolyl amide compounds and uses thereof. The compounds have structures as represented by the general formula I, wherein the definitions of each substituent showed in the specification. The compounds of formula I are novel and have excellent insecticidal and fungicidal activities and can be used for controlling insect pest and diseases.
摘要翻译：本发明涉及一种1-取代的吡啶基吡唑基酰胺化合物及其用途。化合物具有由通式I表示的结构，其中每个取代基的定义在说明书中显示。式I化合物是新颖的，具有优异的杀虫和杀真菌活性，可用于防治害虫和疾病。

8. 发明授权

US08492409B2 1-substituted pyridyl-pyrazolyl amide compounds and uses thereof 有权
标题翻译： 1-取代的吡啶基 - 吡唑基酰胺化合物及其用途
公开(公告)号：US08492409B2
公开(公告)日：2013-07-23
申请号：US12990193
申请日：2009-07-03
申请人： Bin Li , Huibin Yang , Junfeng Wang , Haibo Yu , Hong Zhang , Zhinian Li , Yuquan Song
发明人： Bin Li , Huibin Yang , Junfeng Wang , Haibo Yu , Hong Zhang , Zhinian Li , Yuquan Song
IPC分类号： A01N43/40 , C07D401/04
CPC分类号： C07D401/04 , A01N43/56
摘要： The present invention discloses a kind of 1-substituted pyridyl-pyrazolyl amide compounds and uses thereof. The compounds have structures as represented by the general formula I, wherein the definitions of each substituent showed in the specification. The compounds of formula I are novel and have excellent insecticidal and fungicidal activities and can be used for controlling insect pest and diseases.
摘要翻译：本发明公开了一种1-取代的吡啶基吡唑基酰胺化合物及其用途。化合物具有由通式I表示的结构，其中每个取代基的定义在说明书中显示。式I化合物是新颖的，具有优异的杀虫和杀真菌活性，可用于防治害虫和疾病。

9. 发明申请

US20100137249A1 COMPOSITIONS FOR REGULATING OR MODULATING QUORUM SENSING IN BACTERIA, METHODS OF USING THE COMPOUNDS, AND METHODS OF REGULATING OR MODULATING QUORUM SENSING IN BACTERIA 有权
标题翻译：用于调节或调节细菌中的相同感测的组合物，使用该化合物的方法，以及调节或调节细菌感测方法
公开(公告)号：US20100137249A1
公开(公告)日：2010-06-03
申请号：US12597825
申请日：2008-06-06
申请人： Binghe Wang , Nanting Ni , Junfeng Wang , Chung-Dar Lu , Han-Ting Chou , Minyong Li , Shilong Zheng , Yunfeng Cheng , Hanjing Peng
发明人： Binghe Wang , Nanting Ni , Junfeng Wang , Chung-Dar Lu , Han-Ting Chou , Minyong Li , Shilong Zheng , Yunfeng Cheng , Hanjing Peng
IPC分类号： A01N55/08 , C07F5/02 , C12Q1/02
CPC分类号： C07D333/34 , C07F5/025
摘要： The present disclosure encompasses compounds and compositions that are useful as specific AI-2 antagonists for the control of bacterial quorum sensing. Although the AI-2 antagonists according to the present disclosure may not have bactericidal effect, their ability to attenuate virulence, drug resistance, and/or biofilm formation have therapeutic benefits. In addition, the AI-2 antagonists of the present disclosure can also be used as tools to probe bacterial AI-2 functions. The present disclosure also encompasses methods for inhibiting or attenuating microbial virulence, biofilm formation, and drug resistance. The methods are suitable for preventing bacteria from accruing and forming extensive biofilms that may be a health or hygiene hazard or a physical issue, such as in the blockage of water or fuel lines.
摘要翻译：本公开涵盖可用作用于控制细菌群体感测的特异性AI-2拮抗剂的化合物和组合物。虽然根据本公开的AI-2拮抗剂可能不具有杀菌作用，但是它们减轻毒力，耐药性和/或生物膜形成的能力具有治疗益处。此外，本公开的AI-2拮抗剂也可以用作探针细菌AI-2功能的工具。本公开还包括抑制或减弱微生物毒力，生物膜形成和耐药性的方法。该方法适用于防止细菌累积和形成广泛的生物膜，这些生物膜可能是健康或卫生危害或物理问题，例如堵塞水或燃料管线。

10. 发明申请

US20190012903A1 SYSTEMS, METHODS, AND DEVICES FOR CALIBRATING PARTICULATE MATTER SENSORS 审中-公开
公开(公告)号：US20190012903A1
公开(公告)日：2019-01-10
申请号：US16063106
申请日：2015-12-16
申请人： Kevin CAI , Junfeng WANG , Honeywell International Inc.
发明人： Kevin Cai , Junfeng Wang
IPC分类号： G08B29/20 , G08B17/10 , G01N33/00
摘要： System (100) for calibrating particulate matter sensors includes a chamber (102) including a plurality of particulate matter sensors (104-1,104-2,104-3,104-N), a fan (110), a particulate matter source (108), an air cleaner (112), and a reference particulate matter sensor (106), a computing device (114) having a processor (118) and a memory (116) storing instructions which, when executed by the processor (118), cause the processor (118) to activate the particulate matter source (108) and the fan (110) until the reference concentration reaches a threshold, activate the air cleaner (112) responsive to the threshold being reached until the reference concentration reaches a calibration point, receive a respective determined mass concentration from each of the plurality of particulate matter sensors (104-1,104-2,104-3,104-N) at the calibration point, and calibrate each of the plurality of particulate matter sensors (104-1,104-2,104-3,104-N) based, at least in part, on a respective relationship between the reference concentration and each determined mass concentration at the calibration point. Methods and devices for calibrating particulate matter sensors are also described.

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