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    • 2. 发明授权
    • Drug, preparation and use thereof
    • 药物,制剂及其用途
    • US4918099A
    • 1990-04-17
    • US844325
    • 1986-03-26
    • Chang-Kiu Moon
    • Chang-Kiu Moon
    • A61K31/35A61K31/365A61K36/00A61K36/48C07D311/94C07D493/04
    • C07D311/94A61K31/35A61K31/365A61K36/48Y10S514/822Y10S514/833Y10S514/866Y10S514/884
    • A novel drug comprises as active ingredient an extract extractable from plant material of plants belonging to the genus Caesalpinia, one or several components of this extract and/or one or several substances present in this extract or derived therefrom but prepared synthetically.These substances are in particular benz(b)indeno(2.1-d)pyran derivatives, including brazilin, brazilein, hematoxylin and/or hematein. The drug is especially suited for treatment of a patient suffering from micro-circulatory disorders, diabetes mellitus, increased blood sugar values, increasing blood platelet aggregation, increased blood viscosity, decreased eryhtrocyte deformability, disorders of the lysosomal enzyme activity and/or suffering from disorders of the prostaglandin metabolism, especially increasing thromboxane A.sub.2 activity.
    • 一种新药包含作为活性成分的可从属于凯撒刺属的植物的植物材料提取的提取物,该提取物的一种或多种组分和/或该提取物中存在的一种或多种物质,或由其衍生而来,但合成制备。 这些物质特别是苯并(b)茚并(2.1-d)吡喃衍生物,包括巴西,巴西林,苏木精和/或hematein。 该药物特别适用于治疗患有微循环障碍,糖尿病,血糖值升高,血小板聚集增加,血液粘度升高,红细胞变形能力降低,溶酶体酶活性紊乱和/或患有疾病的患者 的前列腺素代谢,特别是增加血栓素A2活性。