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1. 发明授权

US5562100A Method for laser induced fluorescence of tissue 失效
标题翻译：激光诱导组织荧光的方法
公开(公告)号：US5562100A
公开(公告)日：1996-10-08
申请号：US249086
申请日：1994-05-25
申请人： Carter Kittrell , Robert M. Cothren , Michael S. Feld , Joseph J. Baraga , Kyungwon An , Rebecca Richards-Kortum , Richard P. Rava , Young D. Park , Anand V. Mehta , Paola Taroni , Lucene Tong , Ramachandra R. Dasari
发明人： Carter Kittrell , Robert M. Cothren , Michael S. Feld , Joseph J. Baraga , Kyungwon An , Rebecca Richards-Kortum , Richard P. Rava , Young D. Park , Anand V. Mehta , Paola Taroni , Lucene Tong , Ramachandra R. Dasari
IPC分类号： A61B5/00 , A61B18/24
CPC分类号： A61B5/0084 , A61B18/245 , A61B5/0071 , A61B5/0075 , A61B5/1459 , A61B2562/0238
摘要： A method for laser induced fluorescence of tissue in which laser radiation is used to illuminate and induce fluorescence in the tissue under study to determine the chemical composition or pathologic condition of tissue. The laser radiation and the retrieved fluorescing radiation can be conveyed through a catheter using an array of optical fiber. The fluorescence spectrum of the tissue can be displayed and analyzed to obtain information regarding the chemical composition and medical condition of the tissue inside the human body.
摘要翻译：激光诱导荧光组织的方法，其中使用激光辐射来照射和诱导正在研究的组织中的荧光以确定组织的化学组成或病理状况。激光辐射和所检索的荧光辐射可以使用光纤阵列通过导管输送。可以显示和分析组织的荧光光谱，以获得关于人体内组织的化学成分和医疗状况的信息。

2. 发明授权

US5419323A Method for laser induced fluorescence of tissue 失效
标题翻译：激光诱导组织荧光的方法
公开(公告)号：US5419323A
公开(公告)日：1995-05-30
申请号：US720465
申请日：1991-08-29
申请人： Carter Kittrell , Robert M. Cothren , Michael S. Feld , Joseph J. Baraga , Kyungwon An , Rebecca Richards-Kortum , Richard P. Rava , Young D. Park , Anand Mehta , Paola Taroni , Lucene Tong , Ramachandra R. Dasari
发明人： Carter Kittrell , Robert M. Cothren , Michael S. Feld , Joseph J. Baraga , Kyungwon An , Rebecca Richards-Kortum , Richard P. Rava , Young D. Park , Anand Mehta , Paola Taroni , Lucene Tong , Ramachandra R. Dasari
IPC分类号： A61B5/00 , A61B18/24 , A61B6/00
CPC分类号： A61B5/0084 , A61B18/245 , A61B5/0071 , A61B5/0075 , A61B5/1459 , A61B2562/0238
摘要： A method for laser induced fluorescence of tissue in which laser radiation is used to illuminate and induce fluorescence in the tissue under study to determine the chemical composition or pathologic condition of tissue. The laser radiation and the retrieved fluorescing radiation can be conveyed through a catheter using an array of optical fiber. The fluorescence spectrum of the tissue can be displayed and analyzed to obtain information regarding the chemical composition and medical condition of the tissue inside the human body.
摘要翻译： PCT No.PCT / US89 / 05174 Sec。 371日期：1993年5月7日 102（e）日期1993年5月7日PCT提交1989年11月17日PCT公布。出版物WO90 / 06718 日期：1990年6月28日。一种激光诱导荧光组织的方法，其中使用激光辐射来照射和诱导研究组织中的荧光以确定组织的化学组成或病理状况。激光辐射和所检索的荧光辐射可以使用光纤阵列通过导管输送。可以显示和分析组织的荧光光谱，以获得关于人体内组织的化学成分和医疗状况的信息。

3. 发明授权

US5859867A Microlaser 失效
标题翻译：微型激光
公开(公告)号：US5859867A
公开(公告)日：1999-01-12
申请号：US565344
申请日：1995-11-30
申请人： Kyungwon An , James J. Childs , Ramachandra Rao Dasari , Michael S. Feld
发明人： Kyungwon An , James J. Childs , Ramachandra Rao Dasari , Michael S. Feld
IPC分类号： H01S3/06 , H01S3/091
CPC分类号： H01S3/08031 , H01S3/0604 , H01S3/10
摘要： In a single-atom microlaser, a pair of opposed reflectors define a high-finesse or "high-Q" optical cavity therebetween. A source delivers a stream of multiple-energy-level atoms or particles into the cavity. Each individual atom in the stream is excited by a pump from a lower energy level to an upper energy level before injection into the cavity. The cavity resonance frequency is substantially matched to the frequency of a photon emitted by each atom as it enters the cavity. The photon is emitted due to a transition in energy between the upper level and lower level of each atom. In this manner, upon entry of a sequence of individual atoms into the cavity for example, the average number of photons resonating in the cavity exceeds one and the average number of atoms in the cavity is less than one. The photons are sustained in the high-Q cavity for a long enough time period such that the photon field interacts with the next atom in the stream. A beam of coherent light in the optical frequency spectrum is emitted from the cavity.
摘要翻译：在单原子微激光器中，一对相对的反射器在它们之间限定高精度或“高Q”光学腔。源将多能级原子或颗粒流输送到空腔中。流中的每个单独的原子在注入空腔之前被泵从较低的能级激发到较高的能级。空腔谐振频率基本上与每个原子在进入腔体时发射的光子的频率相匹配。光子由于每个原子的上层和下层之间的能量过渡而被发射。以这种方式，例如，当单个原子序列进入空腔时，在空腔中谐振的光子的平均数量超过1，并且空腔中的平均原子数小于1。光子在高Q空穴中持续足够长的时间段，使得光子场与流中的下一个原子相互作用。光学频谱中的相干光束从腔体发射出来。

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