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1. 发明授权

US07223597B2 Anti-apoptosis genes and methods of use thereof 失效
标题翻译：抗凋亡基因及其使用方法
公开(公告)号：US07223597B2
公开(公告)日：2007-05-29
申请号：US10167015
申请日：2002-06-11
申请人： Carl R. Simmons , William J. Gordon-Kamm , Gurmukh S. Johal , Pedro A. Navarro Acevedo , Yumin Tao
发明人： Carl R. Simmons , William J. Gordon-Kamm , Gurmukh S. Johal , Pedro A. Navarro Acevedo , Yumin Tao
IPC分类号： C12N15/82 , C12N15/29
CPC分类号： C12N15/8261 , C07K14/415 , C12N15/8263 , Y02A40/146
摘要： The invention provides isolated nucleic acids and their encoded proteins that act as cell death inhibitors and methods of use thereof. The invention further provides expression cassettes, transformed host cells, transgenic plants and plant parts, and antibody compositions.
摘要翻译：本发明提供了作为细胞死亡抑制剂的分离的核酸及其编码的蛋白质及其使用方法。本发明进一步提供表达盒，转化的宿主细胞，转基因植物和植物部分以及抗体组合物。

2. 发明授权

US07276584B1 Isolated nucleic acid molecules encoding the Br2 P-glycoprotein of maize and methods of modifying growth in plants transformed therewith 有权
公开(公告)号：US07276584B1
公开(公告)日：2007-10-02
申请号：US11338199
申请日：2006-01-24
申请人： Gurmukh S. Johal , Dilbag S. Multani , Steven P. Briggs
发明人： Gurmukh S. Johal , Dilbag S. Multani , Steven P. Briggs
IPC分类号： C07K1/00
CPC分类号： C07K14/415
摘要： The invention relates to the genetic modification of plants, particularly to the expression of P-glycoprotein genes in transformed plants. Nucleotide sequences for the Br2 gene encoding a P-glycoprotein of maize and methods for their use are provided. The sequences find use in modifying the growth of plants.

3. 发明授权

US06784341B2 Defense-related signaling genes and methods of use 失效
标题翻译：国防相关信号基因和使用方法
公开(公告)号：US06784341B2
公开(公告)日：2004-08-31
申请号：US09952689
申请日：2001-09-14
申请人： Gurmukh S. Johal , Dilbag Multani
发明人： Gurmukh S. Johal , Dilbag Multani
IPC分类号： A61H100
CPC分类号： C12N15/8282 , C07K14/415
摘要： The invention provides isolated SNAP25 nucleic acids, their encoded proteins, and a loss-of-function phenotype of the SNAP25 gene. The present invention provides methods and compositions relating to altering SNAP25 concentration and/or composition of plants. The invention further provides recombinant expression cassettes, host cells, and transgenic plants.
摘要翻译：本发明提供了分离的SNAP25核酸，其编码的蛋白质和SNAP25基因的功能丧失表型。本发明提供了与改变植物的SNAP25浓度和/或组成有关的方法和组合物。本发明还提供了重组表达盒，宿主细胞和转基因植物。

4. 发明授权

US06455297B1 Methods and compositions for regulating cell death and enhancing disease resistance to plant pathogens 有权
标题翻译：用于调节细胞死亡并增强对植物病原体的抗病性的方法和组合物
公开(公告)号：US06455297B1
公开(公告)日：2002-09-24
申请号：US09923654
申请日：2001-08-07
申请人： Gurmukh S. Johal , Steven P. Briggs , John Gray , Gongshe Hu
发明人： Gurmukh S. Johal , Steven P. Briggs , John Gray , Gongshe Hu
IPC分类号： C12N988
CPC分类号： C12N15/8261 , C12N9/88 , C12N15/8242 , C12N15/8243 , C12N15/8263 , C12N15/8282 , C12N15/8289 , Y02A40/146
摘要： Compositions and methods for enhancing disease resistance to a pathogen in a plant are provided. Methods of the invention comprise stably transforming a plant with an antisense nucleotide sequence for a gene encoding an enzyme in the C-5 porphyrin metabolic pathway and operably linking said antisense sequence to a pathogen-inducible promoter, such that invasion of a cell by a pathogen elicits a hypersensitive-like response that results in confinement of the pathogen to cells of initial contact. Transformed plants and seeds are provided. Nucleotide sequences encoding a wild-type maize urod gene useful in the present invention and the amino acid sequence for the protein encoded thereby are provided. These compositions are also useful for regulating cell death in specifically targeted tissues. A maize lesion mimic, dominant mutant phenotype, designated Les22, and the molecular basis for its manifestation are also provided.
摘要翻译：提供了用于提高植物中对病原体的抗病性的组合物和方法。本发明的方法包括用编码C-5卟啉代谢途径中的酶的基因的反义核苷酸序列稳定转化植物，并将所述反义序列可操作地连接到病原体诱导型启动子，使得病原体侵入细胞引起过敏反应，导致病原体与初始接触细胞的限制。提供了转化的植物和种子。提供了编码本发明中有用的野生型玉米urod基因的核苷酸序列和由此编码的蛋白质的氨基酸序列。这些组合物也可用于调节特异性靶向组织中的细胞死亡。还提供了玉米病变模拟物，显性突变体表型，命名为Les22，以及其表现的分子基础。

5. 发明授权

US06211437B1 Nucleic acids from maize encoding proteins which suppress plant cell death 失效
标题翻译：来自玉米编码蛋白质的核酸抑制植物细胞死亡
公开(公告)号：US06211437B1
公开(公告)日：2001-04-03
申请号：US08810009
申请日：1997-03-04
申请人： Steven P. Briggs , Gurmukh S. Johal , John Gray
发明人： Steven P. Briggs , Gurmukh S. Johal , John Gray
IPC分类号： A01H500
CPC分类号： C12N9/0071 , C12N15/8207 , C12N15/8282 , C12N15/8289
摘要： The present invention is drawn to genes from maize encoding proteins which suppress plant cell death and methods of plant transformation therewith.
摘要翻译：本发明涉及抑制植物细胞死亡的玉米编码蛋白质的基因及其植物转化方法。

6. 发明授权

US07612256B2 Isolated nucleic acid molecules encoding the Br2 P-glycoprotein of maize and methods of modifying growth in plants transformed therewith 有权
标题翻译：编码玉米的Br2P-糖蛋白的分离的核酸分子以及用其转化的植物中改变生长的方法
公开(公告)号：US07612256B2
公开(公告)日：2009-11-03
申请号：US11338356
申请日：2006-01-24
申请人： Gurmukh S. Johal , Dilbag S. Multani , Steven P. Briggs
发明人： Gurmukh S. Johal , Dilbag S. Multani , Steven P. Briggs
IPC分类号： C12N15/82 , C12N15/29 , A01H5/00 , A01H5/10
CPC分类号： C07K14/415 , C12N15/8261 , Y02A40/146
摘要： The invention relates to the genetic modification of plants, particularly to the expression of P-glycoprotein genes in transformed plants. Nucleotide sequences for the Br2 gene encoding a P-glycoprotein of maize and methods for their use are provided. The sequences find use in modifying the growth of plants.
摘要翻译：本发明涉及植物的遗传修饰，特别涉及转化植物中P-糖蛋白基因的表达。提供了编码玉米P-糖蛋白的Br2基因的核苷酸序列及其使用方法。这些序列用于修饰植物的生长。

7. 发明授权

US07276647B2 Isolated nucleic acid molecules encoding the Dw3 P-glycoprotein of sorghum and methods of modifying growth in transgenic plants therewith 有权
标题翻译：编码高粱Dw3P-糖蛋白的分离的核酸分子及其转基因植物的生长修饰方法
公开(公告)号：US07276647B2
公开(公告)日：2007-10-02
申请号：US10795931
申请日：2004-03-08
申请人： Gurmukh S. Johal , Dilbag S. Multani
发明人： Gurmukh S. Johal , Dilbag S. Multani
IPC分类号： A01H5/00 , A01H5/10 , C12N15/29 , C12N15/82
CPC分类号： C12N15/8261 , C07K14/415 , Y02A40/146
摘要： The invention relates to the genetic manipulation of organisms, particularly to the expression of P-glycoprotein genes in transformed plants and other organisms. Nucleotide sequences for the P-glycoprotein genes, particularly the Dw3 gene of sorghum, and methods for their use are provided. The sequences find use in modifying the growth of organisms, particularly plants. Additionally, the invention provides methods for producing stable dwarf crop plants, particularly stable dwarf sorghum plants.
摘要翻译：本发明涉及生物体的遗传操作，特别是转化植物和其他生物体中P-糖蛋白基因的表达。提供P-糖蛋白基因，特别是高粱Dw3基因的核苷酸序列及其使用方法。这些序列用于修饰生物体，特别是植物的生长。此外，本发明提供了生产稳定的矮秆作物，特别是稳定的矮秆高粱植物的方法。

8. 发明授权

US06271439B1 Methods and compositions for regulating cell death and enhancing disease resistance to plant pathogens 有权
标题翻译：用于调节细胞死亡并增强对植物病原体的抗病性的方法和组合物
公开(公告)号：US06271439B1
公开(公告)日：2001-08-07
申请号：US09260843
申请日：1999-03-02
申请人： Gurmukh S. Johal , Steven P. Briggs , John Gray , Gongshe Hu
发明人： Gurmukh S. Johal , Steven P. Briggs , John Gray , Gongshe Hu
IPC分类号： C12N1529
CPC分类号： C12N15/8261 , C12N9/88 , C12N15/8242 , C12N15/8243 , C12N15/8263 , C12N15/8282 , C12N15/8289 , Y02A40/146
摘要： Compositions and methods for enhancing disease resistance to a pathogen in a plant are provided. Methods of the invention comprise stably transforming a plant with an antisense nucleotide sequence for a gene encoding an enzyme in the C-5 porphyrin metabolic pathway and operably linking the antisense sequence to a pathogen-inducible promoter, such that invasion of a cell by a pathogen elicits a hypersensitive-like response that results in confinement of the pathogen to cells of initial contact. Transformed plants and seeds are provided. Nucleotide sequences encoding a wild-type maize urod gene useful in the present invention and the amino acid sequence for the protein encoded thereby are provided. These compositions are also useful for regulating cell death in specifically targeted tissues. A maize lesion mimic, dominant mutant phenotype, designated Les22, and the molecular basis for its manifestation are also provided.
摘要翻译：提供了用于提高植物中对病原体的抗病性的组合物和方法。本发明的方法包括用编码C-5卟啉代谢途径中的酶的基因的反义核苷酸序列稳定转化植物，并将反义序列可操作地连接到病原体诱导型启动子，使得病原体侵入细胞引起过敏反应，导致病原体与初始接触细胞的限制。提供了转化的植物和种子。提供了编码本发明中有用的野生型玉米urod基因的核苷酸序列和由此编码的蛋白质的氨基酸序列。这些组合物也可用于调节特异性靶向组织中的细胞死亡。还提供了玉米病变模拟物，显性突变体表型，命名为Les22，以及其表现的分子基础。

9. 发明授权

US5589611A Disease resistance gene from maize and its use for disease resistance as a selectable marker and as a gene identification probe 失效
标题翻译：来自玉米的抗病基因及其作为抗病性的用途作为选择性标记和作为基因鉴定探针
公开(公告)号：US5589611A
公开(公告)日：1996-12-31
申请号：US123761
申请日：1993-09-17
申请人： Steven P. Briggs , Gurmukh S. Johal
发明人： Steven P. Briggs , Gurmukh S. Johal
IPC分类号： C07K14/415 , C12N1/21 , C12N9/02 , C12N15/29 , C12N15/53 , C12N15/82 , A01H1/04 , C07H21/04 , C12N5/00 , C12N15/00
CPC分类号： C12N9/0004 , C07K14/415 , C12N15/8282
摘要： The HM1 gene in maize confers race-specific resistance to the pathogen, Cochliobolus carbonum. We have used transposon mutagenesis to tag, clone, and characterize several HM1 alleles. The gene can be used as a selectable marker in conjunction with the toxin produced by C. carbonum.
摘要翻译：玉米中的HM1基因赋予对病原体碳酸杆菌的种族特异性抗性。我们已经使用转座子诱变来标记，克隆和表征几种HM1等位基因。该基因可以与碳酸钙生产的毒素结合使用作为选择标记。

10. 发明申请

US20110225665A1 Stable dw3 Allele for Sorghum and a Molecular Marker to Facilitate Selection 审中-公开
标题翻译：稳定的dw3等位基因用于高粱和分子标记以促进选择
公开(公告)号：US20110225665A1
公开(公告)日：2011-09-15
申请号：US13047594
申请日：2011-03-14
申请人： Mitchell Reed Tuinstra , Gurmukh S. Johal
发明人： Mitchell Reed Tuinstra , Gurmukh S. Johal
IPC分类号： A01H1/00 , C07H21/04 , A01H5/00 , A01H5/10 , C12Q1/68 , C07H21/00
CPC分类号： C12Q1/6895 , A01H1/04 , A01H5/10 , C12Q2600/13 , C12Q2600/156
摘要： The identification of a stable dw3 allele and development of molecular DNA markers to facilitate selection of this allele in development of new cultivars provides a simple genetic solution to the problem of tall height mutants in commercial sorghum [Sorghum bicolor (L.) Moench] parent lines and hybrids.
摘要翻译：鉴定稳定的dw3等位基因和开发分子DNA标记物以促进新品种开发中该等位基因的选择为商业高粱（Sorghum bicolor（L.）Moench]亲本系中高高度突变体的问题提供了简单的遗传解决方案和杂种。

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