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1. 发明申请

US20130027186A1 ULTRALOW-POWER IMPLANTABLE HUB-BASED WIRELESS IMPLANTABLE SENSOR COMMUNICATION 审中-公开
标题翻译：超低功耗可嵌入式无线可插拔传感器通信
公开(公告)号：US20130027186A1
公开(公告)日：2013-01-31
申请号：US13190737
申请日：2011-07-26
申请人： Can Cinbis , Michael A. Schugt , Richard J. O'Brien
发明人： Can Cinbis , Michael A. Schugt , Richard J. O'Brien
IPC分类号： H04Q5/22
CPC分类号： A61B5/0031 , A61B5/0002 , A61B5/0028 , A61B2560/0209 , A61N1/37211
摘要： Communication power in a medical device system is managed by providing power from a power supply to a communication circuit in a sensing device according to a first communication wake up mode set for a first time period and according to a second communication wake up mode set for a second time period. The second communication wake-up mode is established by a second device.
摘要翻译：医疗设备系统中的通信电力是根据第一时间段设定的第一通信唤醒模式和根据第二通信唤醒模式设置的，从电源向感测设备中的通信电路提供电力来管理的第二时间段第二通信唤醒模式由第二设备建立。

2. 发明授权

US07684872B2 Contactless interconnect for transducers 失效
标题翻译：用于传感器的非接触式互连
公开(公告)号：US07684872B2
公开(公告)日：2010-03-23
申请号：US11380315
申请日：2006-04-26
申请人： James K. Carney , Michael A. Schugt , Qingshan Ye , Can Cinbis
发明人： James K. Carney , Michael A. Schugt , Qingshan Ye , Can Cinbis
IPC分类号： A61N1/08
CPC分类号： A61B5/0422 , A61B5/0215 , A61B5/02158 , A61B5/14532 , A61B5/14539 , A61B5/14546 , A61B2562/028 , A61N1/056 , A61N1/36514
摘要： A medical device for implantation within a patient comprising a lead body including a conductor within the lead body and a transducer supported by the lead body. The conductor is electrically coupled to the transducer by a conductive fluid, paste or gel. The conductive fluid, paste or gel may be contained within a well in the lead body. The transducer may be a MEMS chip and/or an integrated circuit and may perform any of a variety of functions such as sensing physiological data.
摘要翻译：一种用于植入患者体内的医疗装置，包括：引线体，其包括引线体内的导体;以及由引线体支撑的换能器。导体通过导电流体，糊剂或凝胶电耦合到换能器。导电流体，糊状物或凝胶可以包含在引线体内的阱中。换能器可以是MEMS芯片和/或集成电路，并且可以执行诸如感测生理数据的各种功能中的任何一种。

3. 发明授权

US07328131B2 Implantable pedometer 失效
标题翻译：可植入计步器
公开(公告)号：US07328131B2
公开(公告)日：2008-02-05
申请号：US11344999
申请日：2006-02-01
申请人： William T. Donofrio , Jeffrey H. Nycz , Sarah Anne Audet , Can Cinbis , Michael A. Schugt , Gerard J. Hill , Qingshan (Sam) Ye
发明人： William T. Donofrio , Jeffrey H. Nycz , Sarah Anne Audet , Can Cinbis , Michael A. Schugt , Gerard J. Hill , Qingshan (Sam) Ye
IPC分类号： G06F17/00
CPC分类号： A61B5/4528 , A61B5/1118 , A61B5/1123 , A61B5/686 , A61B17/86 , A61B2562/0219 , A61F2/2803 , A61F2/32 , A61F2/34 , A61F2/36 , A61F2/3676 , A61F2/38 , A61F2/3804 , A61F2/40 , A61F2/4202 , A61F2/4261 , A61F2/44 , A61F2/4603 , A61F2/4657 , A61F2002/30448 , A61F2002/3067 , A61F2002/30794 , A61F2002/3085 , A61F2002/3403 , A61F2002/3429 , A61F2002/3611 , A61F2002/3625 , A61F2002/365 , A61F2002/4666 , A61F2002/488 , A61F2220/005 , A61F2250/0002
摘要： An implantable pedometer for measuring the amount of joint use is disclosed. The implantable pedometer includes a sensor adapted for detecting indicators of joint usage. A counter is configured for storing count data corresponding to the number of indicators detected by the sensor and a telemetry circuit is configured for transmitting the count data outside of the body.
摘要翻译：公开了一种用于测量联合使用量的可植入计步器。可植入计步器包括适于检测联合使用指标的传感器。计数器被配置为存储与由传感器检测到的指示符的数量相对应的计数数据，并且遥测电路被配置为在体外发送计数数据。

4. 发明授权

US08463346B2 Absolute calibrated tissue oxygen saturation and total hemoglobin volume fraction 有权
$Absolute calibrated tissue oxygen saturation and total hemoglobin volume fraction$
标题翻译：绝对校准组织氧饱和度和总血红蛋白体积分数
公开(公告)号：US08463346B2
公开(公告)日：2013-06-11
申请号：US12797800
申请日：2010-06-10
申请人： Jonathan L. Kuhn , David A. Anderson , Can Cinbis , Richard J. O'Brien , Yong K. Cho , Thomas J. Mullen , Avram Scheiner , Rodolphe P. Katra
发明人： Jonathan L. Kuhn , David A. Anderson , Can Cinbis , Richard J. O'Brien , Yong K. Cho , Thomas J. Mullen , Avram Scheiner , Rodolphe P. Katra
IPC分类号： A61B5/00
CPC分类号： A61N1/36557 , A61B5/1459 , A61N1/37258
摘要： A medical device for monitoring a patient condition includes a sensor capable of being advanced transvascularly to be positioned along a volume of tissue, the sensor including a first combination of a light source and a light detector to emit light into a volume of tissue and to detect light scattered by the volume of tissue and to generate a first output signal corresponding to an intensity of the detected light. A control module is coupled to the light source to control the light source to emit light at least four spaced-apart light wavelengths, and a monitoring module is coupled to the light detector to receive the output signal and compute a measure of tissue oxygenation using the light detector output signal.
摘要翻译：用于监测患者状况的医疗装置包括能够经血管内先进地沿着组织体积定位的传感器，所述传感器包括光源和光检测器的第一组合，以将光发射到一定体积的组织中并且检测通过组织体积散射的光并产生对应于检测到的光的强度的第一输出信号。控制模块耦合到光源以控制光源发射至少四个间隔开的光波长的光，并且监测模块耦合到光检测器以接收输出信号并且使用光检测器输出信号。

5. 发明授权

US08346332B2 Absolute calibrated tissue oxygen saturation and total hemoglobin volume fraction 有权
$Absolute calibrated tissue oxygen saturation and total hemoglobin volume fraction$
标题翻译：绝对校准组织氧饱和度和总血红蛋白体积分数
公开(公告)号：US08346332B2
公开(公告)日：2013-01-01
申请号：US12797811
申请日：2010-06-10
申请人： Jonathan L. Kuhn , David A. Anderson , Can Cinbis , Richard J. O'Brien , Yong K. Cho , Thomas J. Mullen , Avram Scheiner , Rodolphe P. Katra
发明人： Jonathan L. Kuhn , David A. Anderson , Can Cinbis , Richard J. O'Brien , Yong K. Cho , Thomas J. Mullen , Avram Scheiner , Rodolphe P. Katra
IPC分类号： A61B5/00
CPC分类号： A61N1/36557 , A61B5/1459 , A61N1/37258
摘要： A medical device for monitoring a patient condition includes a first combination of a light source and a light detector to emit light into a volume of tissue, detect light scattered by the volume of tissue, and provide a first output signal corresponding to an intensity of the detected light. A control module is coupled to the light source to control the light source to emit light at least four spaced-apart light wavelengths, and a monitoring module is coupled to the light detector to receive the output signal, compute a measure of tissue oxygenation in response to the light detector output signal, and detect tissue hypoxia using the measure of tissue oxygenation.
摘要翻译：用于监测患者状况的医疗装置包括光源和光检测器的第一组合，以将光发射到组织的体积中，检测由组织体积散射的光，并提供对应于组织的强度的第一输出信号检测到光。控制模块耦合到光源以控制光源发射至少四个间隔开的光波长的光，并且监测模块耦合到光检测器以接收输出信号，计算响应中组织氧合的量度到光检测器输出信号，并使用组织氧合的测量来检测组织缺氧。

6. 发明申请

US20100317941A1 ABSOLUTE CALIBRATED TISSUE OXYGEN SATURATION AND TOTAL HEMOGLOBIN VOLUME FRACTION 有权
标题翻译：绝对的校准组织氧饱和度和总HEMOGLOBIN体积分数
公开(公告)号：US20100317941A1
公开(公告)日：2010-12-16
申请号：US12797811
申请日：2010-06-10
申请人： Jonathan L. Kuhn , David A. Anderson , Can Cinbis , Richard J. O'Brien , Yong K. Cho , Thomas J. Mullen , Avram Scheiner , Rodolphe P. Katra
发明人： Jonathan L. Kuhn , David A. Anderson , Can Cinbis , Richard J. O'Brien , Yong K. Cho , Thomas J. Mullen , Avram Scheiner , Rodolphe P. Katra
IPC分类号： A61B5/1455
CPC分类号： A61N1/36557 , A61B5/1459 , A61N1/37258
摘要： A medical device for monitoring a patient condition includes a first combination of a light source and a light detector to emit light into a volume of tissue, detect light scattered by the volume of tissue, and provide a first output signal corresponding to an intensity of the detected light. A control module is coupled to the light source to control the light source to emit light at least four spaced-apart light wavelengths, and a monitoring module is coupled to the light detector to receive the output signal, compute a measure of tissue oxygenation in response to the light detector output signal, and detect tissue hypoxia using the measure of tissue oxygenation.
摘要翻译：用于监测患者状况的医疗装置包括光源和光检测器的第一组合，以将光发射到组织的体积中，检测由组织体积散射的光，并提供对应于组织的强度的第一输出信号检测到光。控制模块耦合到光源以控制光源发射至少四个间隔开的光波长的光，并且监测模块耦合到光检测器以接收输出信号，计算响应中组织氧合的量度到光检测器输出信号，并使用组织氧合的测量来检测组织缺氧。

7. 发明申请

US20100317940A1 Absolute calibrated tissue oxygen saturation and total hemoglobin volume fraction 有权
$Absolute calibrated tissue oxygen saturation and total hemoglobin volume fraction$
标题翻译：绝对校准组织氧饱和度和总血红蛋白体积分数
公开(公告)号：US20100317940A1
公开(公告)日：2010-12-16
申请号：US12797800
申请日：2010-06-10
申请人： Jonathan L. Kuhn , David A. Anderson , Can Cinbis , Richard J. O'Brien , Yong K. Cho , Thomas J. Mullen , Avram Scheiner , Rodolphe P. Katra
发明人： Jonathan L. Kuhn , David A. Anderson , Can Cinbis , Richard J. O'Brien , Yong K. Cho , Thomas J. Mullen , Avram Scheiner , Rodolphe P. Katra
IPC分类号： A61B5/1455
CPC分类号： A61N1/36557 , A61B5/1459 , A61N1/37258
摘要： A medical device for monitoring a patient condition includes a sensor capable of being advanced transvascularly to be positioned along a volume of tissue, the sensor including a first combination of a light source and a light detector to emit light into a volume of tissue and to detect light scattered by the volume of tissue and to generate a first output signal corresponding to an intensity of the detected light. A control module is coupled to the light source to control the light source to emit light at least four spaced-apart light wavelengths, and a monitoring module is coupled to the light detector to receive the output signal and compute a measure of tissue oxygenation using the light detector output signal.
摘要翻译：用于监测患者状况的医疗装置包括能够经血管内先进地沿着组织体积定位的传感器，所述传感器包括光源和光检测器的第一组合，以将光发射到一定体积的组织中并且检测通过组织体积散射的光并产生对应于检测到的光的强度的第一输出信号。控制模块耦合到光源以控制光源发射至少四个间隔开的光波长的光，并且监测模块耦合到光检测器以接收输出信号并且使用光检测器输出信号。

8. 发明授权

US10179242B2 Tissue oxygenation monitoring in heart failure 有权
公开(公告)号：US10179242B2
公开(公告)日：2019-01-15
申请号：US12797815
申请日：2010-06-10
申请人： Can Cinbis , James K. Carney , Jonathan L. Kuhn , David A. Anderson
发明人： Can Cinbis , James K. Carney , Jonathan L. Kuhn , David A. Anderson
IPC分类号： A61N1/36 , A61B5/145 , A61N1/365
摘要： A medical device for monitoring delivery of a therapy that includes a therapy delivery module to deliver a therapy, a controller to set a therapy delivery control parameter, an optical sensor to produce a signal corresponding to tissue light attenuation, and a processor configured to compute a tissue oxygenation measurement from the optical sensor signal, wherein the controller, the optical sensor, and the processor operate cooperatively to determine a setting of the therapy delivery control parameter corresponding to a maximum tissue oxygenation.

9. 发明授权

US09636059B2 Implantable tissue perfusion sensing system and method 有权
公开(公告)号：US09636059B2
公开(公告)日：2017-05-02
申请号：US13612967
申请日：2012-09-13
申请人： Can Cinbis , James K. Carney
发明人： Can Cinbis , James K. Carney
IPC分类号： G01N33/46 , G01N31/00 , C12M1/00 , A61B5/1459 , A61B5/00 , A61B5/024 , A61B5/046 , A61B5/0464 , A61B5/145 , A61N1/39
CPC分类号： A61B5/1459 , A61B5/0059 , A61B5/024 , A61B5/046 , A61B5/0464 , A61B5/14542 , A61B5/7214 , A61N1/3925
摘要： A medical device for sensing cardiac events that includes a plurality of light sources capable of emitting light at a plurality of wavelengths, and a detector to detect the emitted light. A processor determines a plurality of light measurements in response to the emitted light detected by the detector, updates, for each of the plurality of wavelengths, a first normalization coefficient and a second normalization coefficient in response to the detected emitted light, and adjusts the determined plurality of light measurements in response to the first normalization coefficient and the second normalization coefficient.

10. 发明授权

US08983619B2 Testing communication during implantation 有权
标题翻译：测量植入过程中的沟通
公开(公告)号：US08983619B2
公开(公告)日：2015-03-17
申请号：US12732403
申请日：2010-03-26
申请人： Can Cinbis , H. Toby Markowitz
发明人： Can Cinbis , H. Toby Markowitz
IPC分类号： A61N1/08 , A61B5/00 , A61N1/372 , A61B19/00 , A61N1/375
CPC分类号： A61B5/0028 , A61B5/0031 , A61B2034/2053 , A61B2560/0271 , A61N1/37205 , A61N1/37217 , A61N1/37241 , A61N1/3756
摘要： A system and method are described for testing communication through a patient during implantation using telemetry coupling electrodes on a delivery catheter. In one example, at least two telemetry coupling electrodes may be placed on or within a delivery catheter to test conductive communication with external body electrodes during implantation. In some instances, the telemetry coupling electrodes of the delivery catheter may approximate the spacing of telemetry electrodes on an IMD. In this manner, testing conductively coupled communication with telemetry coupling electrodes of the catheter may be used to mimic the telemetry electrodes on the IMD and determine a target position and/or orientation of an electrode or electrodes of the IMD for successful conductive communication through the body.
摘要翻译：描述了一种系统和方法，用于在植入期间通过患者使用传送导管上的遥测耦合电极来测试通信。在一个示例中，至少两个遥测耦合电极可以放置在输送导管上或内部，以在植入期间测试与外部身体电极的导电连通。在一些情况下，输送导管的遥测耦合电极可以接近IMD上遥测电极的间距。以这种方式，测试与导管的遥测耦合电极的导电耦合通信可以用于模拟IMD上的遥测电极，并且确定IMD的电极或电极的目标位置和/或取向以便通过身体成功地导电连通。

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