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1. 发明授权

US08105552B2 Optical sensor array system for parallel processing of chemical and biochemical information 有权
标题翻译：用于并行处理化学和生物化学信息的光学传感器阵列系统
公开(公告)号：US08105552B2
公开(公告)日：2012-01-31
申请号：US12730550
申请日：2010-03-24
申请人： Caibin Xiao , Radislav A. Potyrailo , William G. Morris , Scott M. Boyette , LiJie Yu , Theodore J. Cecconie , Andrew M. Leach , Prashant V. Shrikhande
发明人： Caibin Xiao , Radislav A. Potyrailo , William G. Morris , Scott M. Boyette , LiJie Yu , Theodore J. Cecconie , Andrew M. Leach , Prashant V. Shrikhande
IPC分类号： B01L3/00 , G01P3/00 , G01N31/00
CPC分类号： G01N21/78 , B01L3/50273 , B01L3/502746 , B01L2200/0621 , B01L2300/0803 , B01L2300/0816 , B01L2300/0864 , B01L2400/0406 , B01L2400/088 , G01N21/253 , G01N21/80 , G01N31/22 , Y10T137/7036
摘要： Total analysis systems and methods for simultaneously monitoring a suite of biological and/or chemical species in water and/or other process systems are disclosed. The system provides a sample-volume controlled sensor array comprising a fluid delivery device and a plurality of optical sensor elements for determining the presence and total concentrations of multiple analytes in the process system simultaneously. Image identification algorithms are provided for identifying the analytes based on image intensity, color pattern, positional arrangement, and the like. The methods incorporate multivariate optimization algorithms to analyze multiple sensor responses. This produces analytical results that are typically difficult to obtain without full system or variable compensation. The improved array response may then be utilized to measure, monitor, and control the concentration of analytes in the chemical or biological sample or water system.
摘要翻译：公开了用于在水和/或其它工艺系统中同时监测一套生物和/或化学物质的总分析系统和方法。该系统提供了一个样本量控制的传感器阵列，其包括流体输送装置和多个光学传感器元件，用于同时确定过程系统中多个分析物的存在和总浓度。提供图像识别算法，用于基于图像强度，颜色图案，位置排列等来识别分析物。该方法结合了多变量优化算法来分析多个传感器响应。这产生的分析结果通常难以在没有完整系统或可变补偿的情况下获得。然后可以利用改进的阵列响应来测量，监测和控制化学或生物样品或水系统中分析物的浓度。

2. 发明申请

US20100178208A1 OPTICAL SENSOR ARRAY SYSTEM FOR PARALLEL PROCESSING OF CHEMICAL AND BIOCHEMICAL INFORMATION 有权
标题翻译：用于平行处理化学和生物化学信息的光学传感器阵列系统
公开(公告)号：US20100178208A1
公开(公告)日：2010-07-15
申请号：US12730550
申请日：2010-03-24
申请人： Caibin Xiao , Radislav A. Potyrailo , William G. Morris , Scott M. Boyette , LiJie Yu , Theodore J. Cecconie , Andrew M. Leach , Prashant V. Shrikhande
发明人： Caibin Xiao , Radislav A. Potyrailo , William G. Morris , Scott M. Boyette , LiJie Yu , Theodore J. Cecconie , Andrew M. Leach , Prashant V. Shrikhande
IPC分类号： G01N21/25 , G01N21/75 , B81B7/00
CPC分类号： G01N21/78 , B01L3/50273 , B01L3/502746 , B01L2200/0621 , B01L2300/0803 , B01L2300/0816 , B01L2300/0864 , B01L2400/0406 , B01L2400/088 , G01N21/253 , G01N21/80 , G01N31/22 , Y10T137/7036
摘要： Total analysis systems and methods for simultaneously monitoring a suite of biological and/or chemical species in water and/or other process systems are disclosed. The system provides a sample-volume controlled sensor array comprising a fluid delivery device and a plurality of optical sensor elements for determining the presence and total concentrations of multiple analytes in the process system simultaneously. Image identification algorithms are provided for identifying the analytes based on image intensity, color pattern, positional arrangement, and the like. The methods incorporate multivariate optimization algorithms to analyze multiple sensor responses. This produces analytical results that are typically difficult to obtain without full system or variable compensation. The improved array response may then be utilized to measure, monitor, and control the concentration of analytes in the chemical or biological sample or water system.
摘要翻译：公开了用于在水和/或其它工艺系统中同时监测一套生物和/或化学物质的总分析系统和方法。该系统提供了一个样本量控制的传感器阵列，其包括流体输送装置和多个光学传感器元件，用于同时确定过程系统中多个分析物的存在和总浓度。提供图像识别算法，用于基于图像强度，颜色图案，位置排列等来识别分析物。该方法结合了多变量优化算法来分析多个传感器响应。这产生的分析结果通常难以在没有完整系统或可变补偿的情况下获得。然后可以利用改进的阵列响应来测量，监测和控制化学或生物样品或水系统中分析物的浓度。

3. 发明授权

US07723120B2 Optical sensor array system and method for parallel processing of chemical and biochemical information 有权
标题翻译：光学传感器阵列系统和化学和生化信息并行处理方法
公开(公告)号：US07723120B2
公开(公告)日：2010-05-25
申请号：US11259643
申请日：2005-10-26
申请人： Caibin Xiao , Radislav A. Potyrailo , William G. Morris , Scott M. Boyette , LiJie Yu , Theodore J. Cecconie , Andrew M. Leach , Prashant V. Shrikhande
发明人： Caibin Xiao , Radislav A. Potyrailo , William G. Morris , Scott M. Boyette , LiJie Yu , Theodore J. Cecconie , Andrew M. Leach , Prashant V. Shrikhande
IPC分类号： G01N21/00 , G06K9/38 , C12Q1/68 , G01N33/543 , F16L7/00
CPC分类号： G01N21/78 , B01L3/50273 , B01L3/502746 , B01L2200/0621 , B01L2300/0803 , B01L2300/0816 , B01L2300/0864 , B01L2400/0406 , B01L2400/088 , G01N21/253 , G01N21/80 , G01N31/22 , Y10T137/7036
摘要： Total analysis systems and methods for simultaneously monitoring a suite of biological and/or chemical species in water and/or other process systems are disclosed. The system provides a sample-volume controlled sensor array comprising a fluid delivery device and a plurality of optical sensor elements for determining the presence and total concentrations of multiple analytes in the process system simultaneously. Image identification algorithms are provided for identifying the analytes based on image intensity, color pattern, positional arrangement, and the like. The methods incorporate multivariate optimization algorithms to analyze multiple sensor responses. This produces analytical results that are typically difficult to obtain without full system or variable compensation. The improved array response may then be utilized to measure, monitor, and control the concentration of analytes in the chemical or biological sample or water system.
摘要翻译：公开了用于在水和/或其它工艺系统中同时监测一套生物和/或化学物质的总分析系统和方法。该系统提供了一个样品量控制的传感器阵列，其包括流体输送装置和多个光学传感器元件，用于同时确定过程系统中多个分析物的存在和总浓度。提供图像识别算法，用于基于图像强度，颜色图案，位置排列等来识别分析物。该方法结合了多变量优化算法来分析多个传感器响应。这产生的分析结果通常难以在没有完整系统或可变补偿的情况下获得。然后可以利用改进的阵列响应来测量，监测和控制化学或生物样品或水系统中分析物的浓度。

4. 发明授权

US07456968B2 Sensor system and methods for improved quantitation of environmental parameters 失效
标题翻译：传感器系统和改进环境参数定量的方法
公开(公告)号：US07456968B2
公开(公告)日：2008-11-25
申请号：US10952635
申请日：2004-09-29
申请人： Radislav A. Potyrailo , William G. Morris , Andrew M. Leach
发明人： Radislav A. Potyrailo , William G. Morris , Andrew M. Leach
IPC分类号： G01N21/00
CPC分类号： G01N21/5907 , B01J2219/00536 , B01J2219/00689 , B01J2219/00702 , B01L3/502715 , B01L3/545 , B01L2300/024 , B01L2300/0806 , G01N35/00069
摘要： A system and method employing optical disk drives for quantitative analysis of chemical and biochemical parameters, in which sensor materials disposed on an optical disk are responsive to physical, chemical, biochemical, and other parameters in the environment. The light interacts with the sensor materials when the light propagates through the sensor material, reflects off the optical media's reflective layer, and propagates back through the sensor region. The interacted light is captured by a photodetector, which outputs a response analog signal, for example, an analog voltage signal, which is indicative of a condition of the environment to which the sensor materials have been exposed. The system includes software algorithms which cause the laser source and optical detector to move to a specified location or logical block address of the disk, measure the optical signal during disk rotation, display a map of the sensor material response, and reduce the noise level in the measured signal.
摘要翻译：一种使用光盘驱动器进行化学和生物化学参数的定量分析的系统和方法，其中设置在光盘上的传感器材料响应于环境中的物理，化学，生物化学和其它参数。当光传播通过传感器材料时，光与传感器材料相互作用，从光学介质的反射层反射并传播回传感器区域。相互作用的光被光电检测器捕获，光电检测器输出响应模拟信号，例如模拟电压信号，其表示传感器材料暴露于的环境的状况。该系统包括使激光源和光学检测器移动到盘的指定位置或逻辑块地址的软件算法，在盘旋转期间测量光信号，显示传感器材料响应的映射，并降低噪声水平测量信号。

5. 发明申请

US20110006878A1 GAMMA STERILIZABLE RFID SYSTEM THAT PREVENTS UNAUTHORIZED OPERATION OF ASSOCIATED DISPOSABLE BIOPROCESS COMPONENTS 有权
标题翻译： GAMMA无菌RFID系统，防止相关的可重复生物成分的未经授权的操作
公开(公告)号：US20110006878A1
公开(公告)日：2011-01-13
申请号：US12921459
申请日：2008-08-20
申请人： Manuel Nyffeler , Radislav A. Potyrailo , Vincent F. Pizzi , William G. Morris , Gerard J. Gach , Vijay Singh
发明人： Manuel Nyffeler , Radislav A. Potyrailo , Vincent F. Pizzi , William G. Morris , Gerard J. Gach , Vijay Singh
IPC分类号： G06F7/04
CPC分类号： G06K19/0723 , C12M41/48 , G06Q20/3278 , G06Q20/409 , G11C11/22
摘要： This invention provides a system and apparatus that is able to authenticate and prevent illegal manufacturing and unauthorized operation of disposable bioprocess components. This invention utilizes a ferro-electric random access memory (FRAM) chip to store error-correctable information on a RFID tag attached to the disposable bioprocess components, where the error-correctable information is written into the memory chip, so that the information can remain in the chip when the RFID tag and disposable bioprocess component is gamma-sterilized. Also, this invention includes a method for authenticating the disposable bioprocess component that reduces liability in that a counterfeit poor quality disposable component is not used on the hardware so the user will not file an unjustified complaint.
摘要翻译：本发明提供一种系统和装置，其能够认证并防止一次性生物处理部件的非法制造和未经授权的操作。本发明利用铁电随机存取存储器（FRAM）芯片来存储附着在一次性生物处理部件上的RFID标签上的错误纠正信息，其中将错误纠正信息写入存储器芯片，使得信息可以保持当RFID标签和一次性生物处理组件被伽马灭菌时在芯片中。此外，本发明还包括一种用于认证一次性生物过程组件的方法，其减少责任，因为在硬件上不使用假劣质的一次性部件，因此用户不会提出不合理的投诉。

6. 发明授权

US08653940B2 Method for preventing an unauthorized use of disposable bioprocess components 有权
标题翻译：防止未经授权使用一次性生物过程组件的方法
公开(公告)号：US08653940B2
公开(公告)日：2014-02-18
申请号：US12921598
申请日：2008-08-20
申请人： Manuel Nyffeler , Radislav A. Potyrailo , Vincent F. Pizzi , William G. Morris , Gerard J. Gach , Vijay Singh
发明人： Manuel Nyffeler , Radislav A. Potyrailo , Vincent F. Pizzi , William G. Morris , Gerard J. Gach , Vijay Singh
IPC分类号： G08B29/00
CPC分类号： G06K7/10009 , G06K7/0008 , G06K19/0723 , G06K19/14 , G06Q10/08 , G11C11/22 , G11C11/221
摘要： This invention provides a system and apparatus that is able to authenticate and prevent illegal manufacturing and unauthorized operation of disposable bioprocess components. This invention utilizes a ferro-electric random access memory chip (FRAM) chip to store error-correctable information on a RFID tag attached to the disposable bioprocess components, where the error-correctable information is written in sequence into the memory chip, so that the redundant information can remain in the chip when the RFID tag and disposable bioprocess component is gamma-sterilized. Also, this invention includes a method for authenticating the disposable bioprocess component that reduces liability in that a counterfeit poor quality disposable component is not used on the hardware so the user will not file an unjustified complaint.
摘要翻译：本发明提供一种系统和装置，其能够认证并防止一次性生物处理部件的非法制造和未经授权的操作。本发明利用铁电随机存取存储器芯片（FRAM）来存储附着在一次性生物处理部件上的RFID标签上的错误纠正信息，其中将错误纠正信息依次写入到存储器芯片中，当RFID标签和一次性生物处理组件被伽马灭菌时，冗余信息可以保留在芯片中。此外，本发明还包括一种用于认证一次性生物过程组件的方法，其减少责任，因为在硬件上不使用假劣质的一次性部件，因此用户不会提出不合理的投诉。

7. 发明授权

US08963684B2 Gamma sterilizable RFID system that prevents unauthorized operation of associated disposable bioprocess components 有权
标题翻译： Gamma可消毒的RFID系统，可防止相关的一次性生物过程组件的未经授权的操作
公开(公告)号：US08963684B2
公开(公告)日：2015-02-24
申请号：US12921459
申请日：2008-08-20
申请人： Manuel Nyffeler , Radislav A. Potyrailo , Vincent F. Pizzi , William G. Morris , Gerard J. Gach , Vijay Singh
发明人： Manuel Nyffeler , Radislav A. Potyrailo , Vincent F. Pizzi , William G. Morris , Gerard J. Gach , Vijay Singh
IPC分类号： H04Q9/00 , G06K19/07 , G06Q20/32 , G06Q20/40 , G11C11/22
CPC分类号： G06K19/0723 , C12M41/48 , G06Q20/3278 , G06Q20/409 , G11C11/22
摘要： This invention provides a system and apparatus that is able to authenticate and prevent illegal manufacturing and unauthorized operation of disposable bioprocess components. This invention utilizes a ferro-electric random access memory (FRAM) chip to store error-correctable information on a RFID tag attached to the disposable bioprocess components, where the error-correctable information is written into the memory chip, so that the information can remain in the chip when the RFID tag and disposable bioprocess component is gamma-sterilized. Also, this invention includes a method for authenticating the disposable bioprocess component that reduces liability in that a counterfeit poor quality disposable component is not used on the hardware so the user will not file an unjustified complaint.
摘要翻译：本发明提供一种系统和装置，其能够认证并防止一次性生物处理部件的非法制造和未经授权的操作。本发明利用铁电随机存取存储器（FRAM）芯片来存储附着在一次性生物处理部件上的RFID标签上的错误纠正信息，其中将错误纠正信息写入存储器芯片，使得信息可以保持当RFID标签和一次性生物处理组件被伽马灭菌时在芯片中。此外，本发明还包括一种用于认证一次性生物过程组件的方法，其减少责任，因为在硬件上不使用假劣质的一次性部件，因此用户不会提出不合理的投诉。

8. 发明申请

US20110006900A1 METHOD FOR PREVENTING AN UNAUTHORIZED USE OF DISPOSABLE BIOPROCESS COMPONENTS 有权
标题翻译：防止未经使用的生物成分组件的使用方法
公开(公告)号：US20110006900A1
公开(公告)日：2011-01-13
申请号：US12921598
申请日：2008-08-20
申请人： Manuel Nyffeler , Radislav A. Potyrailo , Vincent F. Pizzi , William G. Morris , Gerard J. Gach , Vijay Singh
发明人： Manuel Nyffeler , Radislav A. Potyrailo , Vincent F. Pizzi , William G. Morris , Gerard J. Gach , Vijay Singh
IPC分类号： G08B13/14
CPC分类号： G06K7/10009 , G06K7/0008 , G06K19/0723 , G06K19/14 , G06Q10/08 , G11C11/22 , G11C11/221
摘要： This invention provides a system and apparatus that is able to authenticate and prevent illegal manufacturing and unauthorized operation of disposable bioprocess components. This invention utilizes a ferro-electric random access memory chip (FRAM) chip to store error-correctable information on a RFID tag attached to the disposable bioprocess components, where the error-correctable information is written in sequence into the memory chip, so that the redundant information can remain in the chip when the RFID tag and disposable bioprocess component is gamma-sterilized. Also, this invention includes a method for authenticating the disposable bioprocess component that reduces liability in that a counterfeit poor quality disposable component is not used on the hardware so the user will not file an unjustified complaint.
摘要翻译：本发明提供一种系统和装置，其能够认证并防止一次性生物处理部件的非法制造和未经授权的操作。本发明利用铁电随机存取存储器芯片（FRAM）来存储附着在一次性生物处理部件上的RFID标签上的错误纠正信息，其中将错误纠正信息依次写入到存储器芯片中，当RFID标签和一次性生物处理组件被伽马灭菌时，冗余信息可以保留在芯片中。此外，本发明包括一种用于认证一次性生物过程组件的方法，其减少责任，因为在硬件上不使用假劣质的一次性部件，因此用户不会提出不合理的投诉。

9. 发明授权

US5392633A Measuring the strength of abrasive grains 失效
标题翻译：测量磨粒的强度
公开(公告)号：US5392633A
公开(公告)日：1995-02-28
申请号：US16638
申请日：1993-02-12
申请人： William G. Morris
发明人： William G. Morris
IPC分类号： G01N3/34 , B02C4/30 , G01N3/00 , G01N3/56 , G01N33/00 , G01D1/16 , G01N19/02
CPC分类号： G01N3/565 , B02C4/30 , G01N2033/0077 , G01N2203/0087
摘要： An apparatus and method of speedily measuring the strength of individual abrasive grains such as diamonds in which the grains are crushed between two hard rollers and the compressive force exerted on the grain by the rollers at the moment of fracture is measured.
摘要翻译：测量在两个硬辊之间粉碎颗粒的各种磨粒（例如金刚石）的强度和在断裂时由辊施加在颗粒上的压缩力的装置和方法。

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