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1. 发明申请

WO2016210128A1 MICROFLUIDIC DEVICE AND SYSTEM USING ACOUSTIC MANIPULATION 审中-公开
标题翻译：微流量装置和系统使用声学操作
公开(公告)号：WO2016210128A1
公开(公告)日：2016-12-29
申请号：PCT/US2016/039014
申请日：2016-06-23
申请人： CYTONOME/ST, LLC
发明人： KOKSAL, Erin , LAPIDAS, Jack , TANNER, Jeanne
IPC分类号： G01N29/22 , G01N1/10 , G01N33/18
CPC分类号： B01L3/502776 , B01L3/502761 , B01L2200/0652 , B01L2300/0816 , B01L2300/0864 , B01L2400/0436 , B01L2400/0496 , G01N15/1404 , G01N15/1484 , G01N29/22 , G01N2015/1006 , G01N2015/142 , G01N2015/149
摘要： A microfluidic chip assembly having a plurality of microfluidic flow channels is provided. Each channel has a switching region. The microfluidic chip may further include at least one surface acoustic wave generator configured to generate a pressure pulse in the switching regions of the channels to selectively deflect particles in the flow. Attenuation elements and/or channel configurations may be used to prevent acoustic signals from interfering with neighboring switching regions. Alternatively, a microfluidic particle processing system may include a microfluidic chip assembly, a particle processing instrument, and a coupling element. The surface acoustic wave generator may be provided on the particle processing instrument. The microfluidic chip assembly may be configured for operative engagement, via the coupling element, with the particle processing instrument. The coupling element may transmit acoustic energy from the surface acoustic wave generator to the switching regions and/or to focusing regions of the flow channels.
摘要翻译：提供了具有多个微流体流动通道的微流体芯片组件。每个通道都有一个切换区域。微流体芯片还可以包括至少一个表面声波发生器，其被配置为在通道的开关区域中产生压力脉冲以选择性地偏转流中的颗粒。可以使用衰减元件和/或通道配置来防止声信号干扰相邻的切换区域。或者，微流体颗粒处理系统可以包括微流体芯片组件，颗粒处理装置和耦合元件。表面声波发生器可以设置在颗粒处理仪器上。微流控芯片组件可以被配置为经由耦合元件与颗粒处理设备的操作接合。耦合元件可以将声能从声表面波发生器传递到开关区域和/或流动通道的聚焦区域。

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