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1. 发明申请

WO2019237080A1 SYSTEM AND METHOD FOR SAFETY SYRINGE 审中-公开
公开(公告)号：WO2019237080A1
公开(公告)日：2019-12-12
申请号：PCT/US2019/036176
申请日：2019-06-07
申请人： CREDENCE MEDSYSTEMS, INC.
发明人： DIAZ, Stephen H. , TILLACK, Jeff , SHLUZAS, Alan E. , SHANLEY, John F. , THAYER, Dan , STEESE-BRADLEY, Gary , MERHIGE, John
IPC分类号： A61M5/28 , A61M5/32 , A61M5/315
摘要： A system for serially injecting liquids includes a syringe body, proximal and distal stopper members disposed in the syringe body, a first liquid in a distal chamber, a second liquid in a proximal chamber, a plunger member, and a needle hub assembly coupled to a distal needle interface of the syringe body. The plunger member includes a needle retention feature disposed in a plunger interior, an energy-storage member disposed in the plunger interior, and an energy-storage member latching member disposed in the plunger interior. The needle assembly includes a needle having a needle proximal end feature, a hub, and a needle latching member configured to couple the needle to the hub. Manipulating the plunger member to insert the proximal stopper member distally relative to the syringe body initially expels the first liquid, then the second liquid. The needle is at least partially retractable into plunger interior.

2. 发明申请

WO2018213837A1 SYSTEM FOR COLLECTING INJECTION INFORMATION 审中-公开
公开(公告)号：WO2018213837A1
公开(公告)日：2018-11-22
申请号：PCT/US2018/033721
申请日：2018-05-21
申请人： CREDENCE MEDSYSTEMS, INC.
发明人： DIAZ, Stephen H. , SHLUZAS, Alan E. , SHANLEY, John F. , TILLACK, Jeff , MERHIGE, John , LITVACK, Frank , THAYER, Dan
IPC分类号： A61M5/178 , A61M5/315
摘要： A system for measuring injection of a liquid medicine includes a syringe body having proximal and distal ends, a syringe interior, and a syringe flange at the proximal end thereof. The system also includes a stopper member disposed in the syringe interior. The system further includes a plunger member coupled to the stopper member and configured to be manipulated to insert the stopper member distally in the syringe interior relative to the syringe body. Moreover, the system includes a needle coupled to the syringe body at the distal end thereof. In addition, the system includes a sensor flange removably coupled to a syringe body. The sensor flange includes a sensor to measure an injection characteristic and a processor to analyze the injection characteristic to determine an occurrence of an injection event.

3. 发明申请

WO2018085467A2 SYSTEM AND METHOD FOR SAFETY SYRINGE 审中-公开
标题翻译：用于安全注射的系统和方法
公开(公告)号：WO2018085467A2
公开(公告)日：2018-05-11
申请号：PCT/US2017/059617
申请日：2017-11-01
申请人： CREDENCE MEDSYSTEMS, INC.
发明人： SHLUZAS, Alan E. , DIAZ, Stephen H. , SHANLEY, John F. , SEGELKE, Scott , MERHIGE, John
IPC分类号： A61M5/178 , A61M5/28 , A61M5/32
摘要： A system for injecting includes a syringe body defining a proximal opening and a distal needle interface. The system also includes a plunger member defining a plunger interior and configured to be manually manipulated to insert a stopper member relative to the syringe body, the plunger member. The plunger member includes a needle retention feature disposed in the plunger interior, an energy-storage member disposed in the plunger interior, and an energy- storage member latching member disposed in the plunger interior. The system further includes a needle hub assembly coupled to the distal needle interface of the syringe body. The needle assembly includes a needle having a needle proximal end feature, a hub, and a needle latching member configured to couple the needle to the hub. The needle is at least partially retractable into plunger interior. The needle proximal end feature includes an annular distally facing surface.
摘要翻译：用于注射的系统包括限定近侧开口和远侧针头界面的注射器主体。该系统还包括柱塞构件，该柱塞构件限定了柱塞内部并且被配置为被手动操纵以相对于注射器本体，柱塞构件插入止挡构件。柱塞构件包括设置在柱塞内部中的针头保持部件，设置在柱塞内部中的能量存储部件以及设置在柱塞内部中的能量存储部件闩锁部件。该系统还包括连接到注射器本体的远侧针接口的针座组件。针组件包括具有针近端特征的针，毂和被配置为将针连接到毂的针闭锁构件。针至少部分地可缩回到柱塞内部。针近端特征包括环形面向远端的表面。

4. 发明申请

WO2018085458A1 SYSTEM AND METHOD FOR SAFETY SYRINGE 审中-公开
标题翻译：用于安全注射的系统和方法
公开(公告)号：WO2018085458A1
公开(公告)日：2018-05-11
申请号：PCT/US2017/059608
申请日：2017-11-01
申请人： CREDENCE MEDSYSTEMS, INC.
发明人： STEESE-BRADLEY, Gary , DIAZ, Stephen, H. , SHLUZAS, Alan, E. , SHANLEY, John, F. , TILLACK, Jeff , THAYER, Dan , MERHIGE, John
IPC分类号： A61M5/20 , A61M5/24 , A61M5/28 , A61M5/178 , A61M5/32
摘要： A system for mixing drug products and injecting includes a syringe body (34), proximal and distal stopper members (32,36) disposed in the syringe body, a plunger member, and a needle hub assembly coupled to the distal needle interface of the syringe body. The proximal and distal stopper members form a proximal drug chamber (40) between there between and a distal drug chamber (42) between the distal stopper member and a distal end of the syringe body. The plunger member includes a needle retention feature, an energy- storage member, and an energy-storage member latching member all disposed in disposed in a plunger interior. First and second sizes of the respective proximal and distal drug chambers can be modified by movement of the proximal and distal stopper members relative to the syringe body. The needle is at least partially retractable into plunger interior upon manipulation of the plunger member relative to the syringe body.
摘要翻译：用于混合药物产品和注射的系统包括注射器主体（34），布置在注射器主体中的近侧和远侧止动器构件（32,36），柱塞构件以及连接到注射器主体到注射器本体的远侧针接口。近侧和远侧止挡构件在它们之间形成近侧药物腔室（40）以及远侧止挡构件和注射器主体的远侧端部之间的远侧药物腔室（42）。柱塞构件包括全部布置在柱塞内部中的针保持特征件，能量储存构件和能量储存构件闩锁构件。相应的近端和远端药物腔室的第一和第二尺寸可以通过近端和远端止挡件相对于注射器主体的移动来修改。在柱塞构件相对于注射器本体的操纵时，针至少部分地可缩回到柱塞内部。

5. 发明申请

WO2020172633A1 SYSTEM AND METHOD FOR SAFETY SYRINGE 审中-公开
公开(公告)号：WO2020172633A1
公开(公告)日：2020-08-27
申请号：PCT/US2020/019365
申请日：2020-02-21
申请人： CREDENCE MEDSYSTEMS, INC.
发明人： TILLACK, Jeff , SHLUZAS, Alan E. , DIAZ, Stephen H. , STEESE-BRADLEY, Gary , MERHIGE, John , SHANLEY, Conor Edward , LEUNG, Mina M.
IPC分类号： A61M5/19 , A61M5/20 , A61M5/28 , A61J1/06 , A61M5/00 , A61M5/315 , A61M5/31 , B65B3/00 , B65B5/06 , A61M5/32
摘要： A method for preparing a pre-filled multi-chamber injection system includes providing an injection system body, the injection system body defining an open proximal end, a body interior, and an open distal end. The method includes introducing a first substance into a distal end of the body interior. The method includes disposing a distal stopper member in the body interior, the distal stopper member and the injection system body defining proximal and distal chambers in the body interior. The method includes introducing a second substance into the body interior. The method includes disposing a proximal stopper member in the body interior. The method includes inserting an elongate member at least partially into the body interior, the elongate member having a plurality of flow channels for fluidly coupling the proximal and distal chambers. The method includes coupling a plunger member to the proximal stopper member.

6. 发明申请

WO2018085467A3 SYSTEM AND METHOD FOR SAFETY SYRINGE 审中-公开
公开(公告)号：WO2018085467A3
公开(公告)日：2018-05-11
申请号：PCT/US2017/059617
申请日：2017-11-01
申请人： CREDENCE MEDSYSTEMS, INC.
发明人： SHLUZAS, Alan E. , DIAZ, Stephen H. , SHANLEY, John F. , SEGELKE, Scott , MERHIGE, John
IPC分类号： A61M5/178 , A61M5/28 , A61M5/32
摘要： A system for injecting includes a syringe body defining a proximal opening and a distal needle interface. The system also includes a plunger member defining a plunger interior and configured to be manually manipulated to insert a stopper member relative to the syringe body, the plunger member. The plunger member includes a needle retention feature (712) disposed in the plunger interior, an energy-storage member disposed in the plunger interior, and an energy-storage member latching member disposed in the plunger interior. The system further includes a needle hub assembly coupled to the distal needle interface of the syringe body. The needle assembly includes a needle having a needle proximal end feature (84), a hub, and a needle latching member configured to couple the needle to the hub. The needle is at least partially retractable into plunger interior. The needle proximal end feature includes an annular distally facing surface (104).

7. 发明公开

EP3801695A1 SYSTEM AND METHOD FOR SAFETY SYRINGE 审中-公开
公开(公告)号：EP3801695A1
公开(公告)日：2021-04-14
申请号：EP19733357.8
申请日：2019-06-07
申请人： Credence Medsystems, Inc.
发明人： DIAZ, Stephen H. , TILLACK, Jeff , SHLUZAS, Alan E. , SHANLEY, John F. , THAYER, Dan , STEESE-BRADLEY, Gary , MERHIGE, John
IPC分类号： A61M5/28 , A61M5/32 , A61M5/315

8. 发明公开

EP3927396A1 SYSTEM AND METHOD FOR SAFETY SYRINGE 审中-实审
公开(公告)号：EP3927396A1
公开(公告)日：2021-12-29
申请号：EP20713453.7
申请日：2020-02-21
申请人： Credence Medsystems, Inc.
发明人： TILLACK, Jeff , SHLUZAS, Alan E. , DIAZ, Stephen H. , STEESE-BRADLEY, Gary , MERHIGE, John , SHANLEY, Conor Edward , LEUNG, Mina M.
IPC分类号： A61M5/19 , A61M5/20 , A61M5/28 , A61J1/06 , A61M5/00 , A61M5/315 , A61M5/31 , B65B3/00 , B65B5/06 , A61M5/32

9. 发明公开

EP4364768A3 SYSTEM AND METHOD FOR COLLECTING INJECTION INFORMATION 审中-实审
公开(公告)号：EP4364768A3
公开(公告)日：2024-08-07
申请号：EP24165961.4
申请日：2018-05-21
申请人： Credence Medsystems, Inc.
发明人： DIAZ, Stephen H. , SHLUZAS, Alan E. , SHANLEY, John F. , TILLACK, Jeff , MERHIGE, John , LITVACK, Frank , THAYER, Dan
IPC分类号： A61M5/178 , A61M5/315
CPC分类号： A61M5/178 , A61M5/3157 , A61M2205/3320130101 , A61M2205/330620130101 , A61M2205/33220130101 , A61M2205/337520130101 , A61M2205/356920130101 , A61M2205/4320130101 , A61M2205/50220130101
摘要： A system (110) for measuring injection of a liquid medicine, comprising a syringe body (112) having proximal and distal ends, a syringe interior (124), and a syringe flange (126) at the proximal end thereof; a stopper member (114) disposed in the syringe interior (124); a plunger member (116) coupled to the stopper member (114) and configured to be manipulated to insert the stopper member (114) distally in the syringe interior (124) relative to the syringe body (112); a needle (130) coupled to the syringe body (112) at the distal end thereof; and a sensor flange (150) removably coupled to the syringe body (112), the sensor flange (150) comprising a sensor (152) to measure an injection characteristic; and a processor to analyze the injection characteristic to determine an occurrence of an injection event, wherein the sensor is a force sensor (152) and the injection characteristic is a distally directed force applied to the plunger member (116) disposed at least partially in the syringe body (112).

10. 发明公开

EP3534993A2 SYSTEM AND METHOD FOR SAFETY SYRINGE 审中-公开
公开(公告)号：EP3534993A2
公开(公告)日：2019-09-11
申请号：EP17804367.5
申请日：2017-11-01
申请人： Credence Medsystems, Inc.
发明人： SHLUZAS, Alan E. , DIAZ, Stephen H. , SHANLEY, John F. , SEGELKE, Scott , MERHIGE, John
IPC分类号： A61M5/178 , A61M5/28 , A61M5/32

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