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1. 发明申请

WO2004016201A2 STENT AND METHOD OF FORMING A STENT WITH INTEGRAL BARBS 审中-公开
标题翻译：形成具有综合棒的手套的方法和方法
公开(公告)号：WO2004016201A2
公开(公告)日：2004-02-26
申请号：PCT/US2003/025827
申请日：2003-08-15
申请人： COOK INCORPORATED , WILLIAM COOK EUROPE APS , WILLIAM A. COOK AUSTRALIA PTY. LTD.
发明人： CASE, Brian, L. , COOK, William, A. , DEBRYUYNE, Michael, P. , FLAGLE, Jacob, A. , GARRISON, Mike , HOFFA, Andrew, K. , KELLER, Frederick, S. , LEONARD, Raymond, B., II , MEAD, Jason, A. , NICKLESS, Benjamin , OSBORNE, Thomas, A. , PAUL, Ram, H., Jr. , PAVCNIK, Dusan , ROSCH, Josef , SHAEFFER, Darin, G. , SISKEN, Richard, B.
IPC分类号： A61F2/06
CPC分类号： A61F2/2475 , A61F2/07 , A61F2/2412 , A61F2/2418 , A61F2/848 , A61F2/89 , A61F2/90 , A61F2/91 , A61F2/915 , A61F2002/075 , A61F2002/8483 , A61F2220/0016 , A61F2220/0058 , A61F2220/0075 , A61F2230/0026 , A61F2230/005 , A61F2230/0054 , A61F2230/0058 , A61F2230/0091 , A61F2230/0095 , A61F2250/0031 , C25F3/24
摘要： A method for manufacturing a barbed stent includes providing a sheet of stent material, cutting the sheet to form a stent wire with integral barbs extending therefrom, and forming the stent wire into a final stent shape having a longitudinal axis. A stent for deployment within the body of a patient includes integral barbs.
摘要翻译：一种用于制造有肋的支架的方法包括提供支架材料的片材（152），切割片材以形成具有从其延伸的整体倒钩（124）的支架丝线，并将支架丝线形成为具有纵向轴线的最终支架形状。用于在患者体内展开的支架包括一体倒钩。

2. 发明申请

WO2008094504A1 MEDICAL PROSTHESIS AND METHOD OF PRODUCTION 审中-公开
标题翻译：医学遗传和生产方法
公开(公告)号：WO2008094504A1
公开(公告)日：2008-08-07
申请号：PCT/US2008/001089
申请日：2008-01-28
申请人： COOK INCORPORATED , BARR, Aaron, P. , DEBRUYNE, Michael, P. , DITTMAN, Jay, A. , HOFFA, Michael, C. , MEAD, Jason, A. , NICKLESS, Benjamin
发明人： BARR, Aaron, P. , DEBRUYNE, Michael, P. , DITTMAN, Jay, A. , HOFFA, Michael, C. , MEAD, Jason, A. , NICKLESS, Benjamin
IPC分类号： A61F2/90 , B23K26/00
CPC分类号： A61F2/91 , A61F2/915 , A61F2002/075 , A61F2002/8483 , A61F2220/0008 , A61F2220/0016 , A61F2220/0075 , A61F2230/0054 , A61F2250/0068 , Y10T29/49995
摘要： The invention relates to a method for producing a radially expandable prosthesis by laser cutting a pattern in a tubular member, which member has an outer diameter at least as great as the expanded diameter of the prosthesis. The prosthesis may be a Z-stent which can be cut out to have integral barbs or notches along its struts. The apexes between the struts may be relatively thin.
摘要翻译：本发明涉及通过激光切割管状构件中的图案来制造可径向扩张的假体的方法，该构件的外径至少与假体的扩大直径一样大。该假体可以是Z-支架，其可以被切除以沿其支柱具有整体倒钩或凹口。支柱之间的顶点可能相对较薄。

3. 发明申请

WO2003096935A1 FLEXIBLE BARB FOR ANCHORING A PROSTHESIS 审中-公开
标题翻译：灵活的BARB用于锚定预测
公开(公告)号：WO2003096935A1
公开(公告)日：2003-11-27
申请号：PCT/US2003/014285
申请日：2003-05-08
申请人： COOK INCORPORATED
发明人： COOK, William, A. , DEBRUYNE, Michael, P. , NICKLESS, Benjamin , OSBORNE, Thomas, A.
IPC分类号： A61F2/06
CPC分类号： A61F2/82 , A61F2002/8483
摘要： A barbed medical prosthesis (10) is disclosed in which the barb (11) includes a basal portion (13) comprising a point of union (19) with the substrate of origin (15) (such as a strut), an anchoring portion (12) adapted to embed into tissue, and a stress-dispersing portion (14) located between the basal and anchoring portions. In one embodiment the stress-dispersing portion comprises a helical coil (38) having a free winding (20) that is unattached to the strut from which the barb extends. In another embodiment, the stress-dispersing portion comprises a series of bends or curves (24) formed in the barb proximate to the point of union with the strut. The barb can be mechanically attached and/or soldered to the prosthesis, or integrally formed therefrom. A second barb portion (37) and stress-dispersing portion, may also extend from the basal portion.
摘要翻译：公开了一种倒钩医疗假体（10），其中倒钩（11）包括基部（13），该基部包括与原点基底（15）（例如支柱）的联合点（19），锚固部分 12）适于嵌入组织中，以及应力分散部分（14），位于基部和锚定部分之间。在一个实施例中，应力分散部分包括具有自由绕组（20）的螺旋线圈（38），所述自由绕组（20）不与所述倒钩延伸的支柱相连。在另一个实施例中，应力分散部分包括形成在倒钩中的一系列弯曲或曲线（24），所述弯曲部分或曲线（24）靠近与支柱结合的点。倒钩可以机械地附接和/或焊接到假体上，或者由其一体形成。第二倒钩部分（37）和应力分散部分也可以从基部延伸。

4. 发明授权

EP1713416B1 ANCHORING BARB FOR ATTACHMENT TO A MEDICAL PROSTHESIS 有权转让
标题翻译：倒钩用于固定到医用假体
公开(公告)号：EP1713416B1
公开(公告)日：2010-01-20
申请号：EP05706090.7
申请日：2005-01-27
申请人： Med Institute, Inc. , Cook Incorporated
发明人： SISKEN, Richard, S. , CHOULES, Brian, D. , NICKLESS, Benjamin , AGNEW, Charles, W.
IPC分类号： A61F2/82 , A61F2/01
CPC分类号： A61F2/86 , A61F2/02 , A61F2/07 , A61F2/82 , A61F2/848 , A61F2002/8483 , A61F2220/0016
摘要： Disclosed is an anchoring element (1) for an implantable prosthesis (10) that includes a barb (12), wherein the anchoring element, which includes a basal portion, comprises a thin layer of material (14), such as a cannula (16) or sheet of metal, that extends or wraps at least partially around the strut (13) of the prosthesis to which it is attached. The barb is configured to extend outward from the basal portion to penetrate adjacent tissue. The anchoring element is either permanently affixed to the strut, such as by laser or spot welding, crimping, or some other method of bonding, or allowed to slide longitudinally over the strut between two points or stops in order to relieve any excessive loads placed upon the barb that could cause fracture. The anchoring element and strut may be configured to limit axial rotation of the barb, while still allowing longitudinal movement. In another embodiment, the slidable anchoring element may be manipulated following initial deployment to reorient the barb toward the implantation site.

5. 发明公开

EP2107895A1 MEDICAL PROSTHESIS AND METHOD OF PRODUCTION 审中-公开
标题翻译：医疗移植和方法
公开(公告)号：EP2107895A1
公开(公告)日：2009-10-14
申请号：EP08724869.6
申请日：2008-01-28
申请人： Cook Incorporated
发明人： BARR, Aaron, P. , DEBRUYNE, Michael, P. , DITTMAN, Jay, A. , HOFFA, Michael, C. , MEAD, Jason, A. , NICKLESS, Benjamin
IPC分类号： A61F2/90 , B23K26/00
CPC分类号： A61F2/91 , A61F2/915 , A61F2002/075 , A61F2002/8483 , A61F2220/0008 , A61F2220/0016 , A61F2220/0075 , A61F2230/0054 , A61F2250/0068 , Y10T29/49995
摘要： The invention relates to a method for producing a radially expandable prosthesis by laser cutting a pattern in a tubular member, which member has an outer diameter at least as great as the expanded diameter of the prosthesis. The prosthesis may be a Z-stent which can be cut out to have integral barbs or notches along its struts. The apexes between the struts may be relatively thin.

6. 发明申请

WO2005072652A1 ANCHORING BARB FOR ATTACHMENT TO A MEDICAL PROSTHESIS 审中-公开
标题翻译：用于附属于医疗保险的锚杆
公开(公告)号：WO2005072652A1
公开(公告)日：2005-08-11
申请号：PCT/US2005/002360
申请日：2005-01-27
申请人： MED INSTITUTE, INC. , COOK INCORPORATED , SISKEN, Richard, S. , CHOULES, Brian, D. , NICKLESS, Benjamin , AGNEW, Charles, W.
发明人： SISKEN, Richard, S. , CHOULES, Brian, D. , NICKLESS, Benjamin , AGNEW, Charles, W.
IPC分类号： A61F2/06
CPC分类号： A61F2/86 , A61F2/02 , A61F2/07 , A61F2/82 , A61F2/848 , A61F2002/8483 , A61F2220/0016
摘要： Disclosed is an anchoring element (1) for an implantable prosthesis (10) that includes a barb (12), wherein the anchoring element, which includes a basal portion, comprises a thin layer of material (14), such as a cannula (16) or sheet of metal, that extends or wraps at least partially around the strut (13) of the prosthesis to which it is attached. The barb is configured to extend outward from the basal portion to penetrate adjacent tissue. The anchoring element is either permanently affixed to the strut, such as by laser or spot welding, crimping, or some other method of bonding, or allowed to slide longitudinally over the strut between two points or stops in order to relieve any excessive loads placed upon the barb that could cause fracture. The anchoring element and strut may be configured to limit axial rotation of the barb, while still allowing longitudinal movement. In another embodiment, the slidable anchoring element may be manipulated following initial deployment to reorient the barb toward the implantation site.
摘要翻译：公开了一种用于可植入假体（10）的锚定元件（1），其包括倒钩（12），其中包括基部部分的锚固元件包括薄层材料（14），例如套管（16））或金属片，其至少部分地围绕其所连接的假体的支柱（13）延伸或包裹。倒钩构造成从基部向外延伸以穿透相邻的组织。锚定元件永久地固定在支柱上，例如通过激光或点焊，压接或某种其它粘合方法，或者允许在两个点或止挡之间在支柱上纵向滑动，以便减轻放置在可能导致骨折的倒钩。锚定元件和支柱可以被配置为限制倒钩的轴向旋转，同时仍允许纵向运动。在另一个实施例中，可以在初始部署之后操纵可滑动锚定元件，以将倒钩朝向植入部位重新定向。

7. 发明授权

EP1503702B1 FLEXIBLE BARB FOR ANCHORING A PROSTHESIS 有权
标题翻译：灵活的倒钩锚固移植
公开(公告)号：EP1503702B1
公开(公告)日：2010-11-03
申请号：EP03753000.3
申请日：2003-05-08
申请人： Cook Incorporated
发明人： COOK, William, A. , DEBRUYNE, Michael, P. , NICKLESS, Benjamin , OSBORNE, Thomas, A.
IPC分类号： A61F2/06
CPC分类号： A61F2/82 , A61F2002/8483
摘要： A barbed medical prosthesis (10) is disclosed in which the barb (11) includes a basal portion (13) comprising a point of union (19) with the substrate of origin (15) (such as a strut), an anchoring portion (12) adapted to embed into tissue, and a stress-dispersing portion (14) located between the basal and anchoring portions. In one embodiment the stress-dispersing portion comprises a helical coil (38) having a free winding (20) that is unattached to the strut from which the barb extends. In another embodiment, the stress-dispersing portion comprises a series of bends or curves (24) formed in the barb proximate to the point of union with the strut. The barb can be mechanically attached and/or soldered to the prosthesis, or integrally formed therefrom. A second barb portion (37) and stress-dispersing portion, may also extend from the basal portion.

8. 发明公开

EP1713416A1 ANCHORING BARB FOR ATTACHMENT TO A MEDICAL PROSTHESIS 有权转让
标题翻译：倒钩用于固定到医用假体
公开(公告)号：EP1713416A1
公开(公告)日：2006-10-25
申请号：EP05706090.7
申请日：2005-01-27
申请人： MED INSTITUTE, INC. , Cook Incorporated
发明人： SISKEN, Richard, S. , CHOULES, Brian, D. , NICKLESS, Benjamin , AGNEW, Charles, W.
IPC分类号： A61F2/06 , A61F2/01
CPC分类号： A61F2/86 , A61F2/02 , A61F2/07 , A61F2/82 , A61F2/848 , A61F2002/8483 , A61F2220/0016
摘要： Disclosed is an anchoring element (1) for an implantable prosthesis (10) that includes a barb (12), wherein the anchoring element, which includes a basal portion, comprises a thin layer of material (14), such as a cannula (16) or sheet of metal, that extends or wraps at least partially around the strut (13) of the prosthesis to which it is attached. The barb is configured to extend outward from the basal portion to penetrate adjacent tissue. The anchoring element is either permanently affixed to the strut, such as by laser or spot welding, crimping, or some other method of bonding, or allowed to slide longitudinally over the strut between two points or stops in order to relieve any excessive loads placed upon the barb that could cause fracture. The anchoring element and strut may be configured to limit axial rotation of the barb, while still allowing longitudinal movement. In another embodiment, the slidable anchoring element may be manipulated following initial deployment to reorient the barb toward the implantation site.

9. 发明公开

EP1503702A1 FLEXIBLE BARB FOR ANCHORING A PROSTHESIS 有权
标题翻译：灵活的倒钩锚固移植
公开(公告)号：EP1503702A1
公开(公告)日：2005-02-09
申请号：EP03753000.3
申请日：2003-05-08
申请人： Cook Incorporated
发明人： COOK, William, A. , DEBRUYNE, Michael, P. , NICKLESS, Benjamin , OSBORNE, Thomas, A.
IPC分类号： A61F2/06
CPC分类号： A61F2/82 , A61F2002/8483
摘要： A barbed medical prosthesis (10) is disclosed in which the barb (11) includes a basal portion (13) comprising a point of union (19) with the substrate of origin (15) (such as a strut), an anchoring portion (12) adapted to embed into tissue, and a stress-dispersing portion (14) located between the basal and anchoring portions. In one embodiment the stress-dispersing portion comprises a helical coil (38) having a free winding (20) that is unattached to the strut from which the barb extends. In another embodiment, the stress-dispersing portion comprises a series of bends or curves (24) formed in the barb proximate to the point of union with the strut. The barb can be mechanically attached and/or soldered to the prosthesis, or integrally formed therefrom. A second barb portion (37) and stress-dispersing portion, may also extend from the basal portion.

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