专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2009067431A2 CONTROLLED DRUG DELIVERY USING A ZEIN LAYER MODIFIED WITH LEVULINIC ACID 审中-公开
标题翻译：控制药物使用改良的维生素A的ZEIN层进行递送
公开(公告)号：WO2009067431A2
公开(公告)日：2009-05-28
申请号：PCT/US2008083869
申请日：2008-11-18
申请人： COOK INC , MED INST , LINDSAY ASHLEY P , PEREZ-SEGARRA WALESKA , RUANE PATRICK H , CASTERLINE CHRISTINE
发明人： LINDSAY ASHLEY P , PEREZ-SEGARRA WALESKA , RUANE PATRICK H , CASTERLINE CHRISTINE
IPC分类号： A61L31/10 , A61L31/16
CPC分类号： A61L29/085 , A61L15/44 , A61L27/34 , A61L27/54 , A61L29/16 , A61L31/10 , A61L31/16 , A61L2300/41 , A61L2300/412 , A61L2300/416 , A61L2300/426 , A61L2420/08 , C08L89/00
摘要： The disclosure relates to medical devices coated with zein admixed with levulinic acid. The medical device may further include a therapeutic agent in contact with zein admixed with levulinic acid. Zein admixed with levulinic acid allows the therapeutic agent to be retained on the device during delivery and also controls the elution rate of the therapeutic agent following implantation. The disclosure further relates to methods of delivering a therapeutic agent on said medical devices as well as their use especially in the form of stents for prevention of restenosis.
摘要翻译：本公开涉及涂覆有与乙酰丙酸混合的玉米醇溶蛋白的医疗装置。医疗装置还可以包括与与乙酰丙酸混合的玉米醇溶蛋白接触的治疗剂。与乙酰丙酸混合的玉米淀粉允许治疗剂在输送期间保留在装置上，并且也控制植入后治疗剂的洗脱速率。本公开还涉及在所述医疗装置上递送治疗剂的方法以及它们的用途，特别是以用于预防再狭窄的支架的形式。

2. 发明申请

WO2007081858A3 ZEIN COATED MEDICAL DEVICE 审中-公开
标题翻译： ZEIN涂层医疗器械
公开(公告)号：WO2007081858A3
公开(公告)日：2008-04-17
申请号：PCT/US2007000378
申请日：2007-01-05
申请人： MED INST INC , RUANE PATRICK H , CASTERLINE CHRISTINE L , VIBBERT AMY M , PEREZ-SEGARRA WALESKA
发明人： RUANE PATRICK H , CASTERLINE CHRISTINE L , VIBBERT AMY M , PEREZ-SEGARRA WALESKA
IPC分类号： A61L31/10 , A61L27/54 , A61L31/16 , C08L89/00
CPC分类号： A61L27/34 , A61L27/54 , A61L31/10 , A61L31/16 , A61L2300/41 , A61L2300/412 , A61L2300/416 , A61L2300/426 , A61L2300/608 , A61L2420/08 , C08L89/00
摘要： The invention relates to medical devices coated with zein. The medical device may include further a therapeutic agent in contact with zein. Zein allows the therapeutic agent to be retained on the device during delivery and also controls the elution rate of the therapeutic agent following implantation. The invention further relates to methods of delivering a therapeutic agent on said medical devices as well as their use especially in the form of stents for prevention of restenosis.
摘要翻译：本发明涉及涂有玉米蛋白的医疗器械。医疗装置还可以包含与玉米醇溶蛋白接触的治疗剂。 Zein允许治疗剂在输送期间保留在装置上，并且还控制植入后治疗剂的洗脱速率。本发明还涉及在所述医疗装置上递送治疗剂的方法以及它们的用途，特别是用于防止再狭窄的支架形式。

3. 发明申请

WO2007062036A3 IMPLANTABLE MEDICAL DEVICE COATINGS WITH BIODEGRADABLE ELASTOMER AND RELEASABLE THERAPEUTIC AGENT 审中-公开
标题翻译：具有生物可降解弹性体和可释放治疗剂的可植入医疗器械涂层
公开(公告)号：WO2007062036A3
公开(公告)日：2008-03-27
申请号：PCT/US2006045055
申请日：2006-11-21
申请人： MED INST INC , REYES PRISCILLA T , RUANE PATRICK H , PEREZ-SEGARRA WALESKA
发明人： REYES PRISCILLA T , RUANE PATRICK H , PEREZ-SEGARRA WALESKA
IPC分类号： A61L31/10
CPC分类号： A61L31/16 , A61L31/10 , A61L2300/416 , A61L2300/608 , A61L2420/08 , C08L67/04
摘要： A coated medical device, such as a stent, that elutes a therapeutic agent in a controlled manner is provided. The medical device may be coated with a layer of therapeutic agent and a layer of bioabsorbable elastomer over the layer of therapeutic agent. Methods of manufacturing a coated medical device and of coating a medical device are also provided.
摘要翻译：提供了以受控方式洗脱治疗剂的涂覆医疗装置，例如支架。医疗装置可以在治疗剂层上涂覆有治疗剂层和生物可吸收弹性体层。还提供了制造涂覆的医疗装置和涂覆医疗装置的方法。

4. 发明申请

WO2008042228A3 MEDICAL DEVICES INCORPORATING A BIOACTIVE AND METHODS OF PREPARING SUCH DEVICES 审中-公开
标题翻译：包含生物活性的医疗装置和制备这些装置的方法
公开(公告)号：WO2008042228A3
公开(公告)日：2008-10-09
申请号：PCT/US2007020875
申请日：2007-09-27
申请人： MED INST INC , RUANE PATRICK H , ISCH ANDREW P , PEREZ-SEGARRA WALESKA
发明人： RUANE PATRICK H , ISCH ANDREW P , PEREZ-SEGARRA WALESKA
IPC分类号： A61L31/16 , A61L31/10
CPC分类号： A61L31/16 , A61L2300/402
摘要： One embodiment provides a medical device comprising a base, material and a bioactive in contact with the base material, the bioactive having a proton binding site with a non-ionic form and an ionic form, the bioactive being less soluble in water when the proton binding site is in the non-ionic form than when the proton binding site is in the ionic form, wherein at least 5% w/w of the bioactive is present with the proton binding site in the non-ionic form and wherein the bioactive is not an anesthetic. Another embodiment provides such a medical device eg. ureteral stent where the bioactive is an anesthetic such as mepivacaine, ropivacaine, bupivacaine or lidocaine and where the device is not a ureteral stent. Another aspect provides method of manufacturing such devices.
摘要翻译：一个实施方案提供了一种医疗装置，其包括与基底材料接触的基底，材料和生物活性物质，所述生物活性物质具有非离子形式和离子形式的质子结合位点，当质子结合时，生物活性较少溶于水位点为质子结合位点为离子形式时的非离子形式，其中至少5％w / w的生物活性物质以非离子形式存在质子结合位点，其中生物活性物质不是麻醉剂另一实施例提供了这种医疗装置，例如输尿管支架，其中生物活性物质是麻醉剂，如甲哌卡因，罗哌卡因，布比卡因或利多卡因，其中该装置不是输尿管支架。另一方面提供了制造这种装置的方法。

5. 发明专利

AT480267T 未知
公开(公告)号：AT480267T
公开(公告)日：2010-09-15
申请号：AT07716420
申请日：2007-01-05
申请人： MED INST INC
发明人： RUANE PATRICK , CASTERLINE CHRISTINE , VIBBERT AMY , PEREZ-SEGARRA WALESKA
IPC分类号： A61L31/10 , A61L27/54 , A61L31/16 , C08L89/00
摘要： The invention relates to medical devices coated with zein. The medical device may include further a therapeutic agent in contact with zein. Zein allows the therapeutic agent to be retained on the device during delivery and also controls the elution rate of the therapeutic agent following implantation. The invention further relates to methods of delivering a therapeutic agent on said medical devices as well as their use especially in the form of stents for prevention of restenosis.

6. 发明专利

DE602007009045D1 ZEIN-BESCHICHTETE MEDIZINISCHE VORRICHTUNG 未知
公开(公告)号：DE602007009045D1
公开(公告)日：2010-10-21
申请号：DE602007009045
申请日：2007-01-05
申请人： MED INST INC
发明人： RUANE PATRICK H , CASTERLINE CHRISTINE L , VIBBERT AMY M , PEREZ-SEGARRA WALESKA
IPC分类号： A61L31/10 , A61L27/54 , A61L31/16 , C08L89/00

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式