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1. 发明申请

WO2009099450A1 ORAL CARE REGIMEN 审中-公开
标题翻译：口腔护理
公开(公告)号：WO2009099450A1
公开(公告)日：2009-08-13
申请号：PCT/US2008/058650
申请日：2008-03-28
申请人： COLGATE-PALMOLIVE COMPANY , ROBINSON, Richard, Scott , SULLIVAN, Richard, J. , PRENCIPE, Michael , VAN RYCKE, Isabelle , LOVELL, Richard , KOHLI, Rajnish , LEITE, Sergio , SIMON, Eric, A. , SANTARPIA, Ralph, Peter, III , CUMMINS, Diane , MELLO, Sarita, V. , CHOPRA, Suman, K. , DEPIERRO, Karen , ZAIDEL, Lynette , CHRISTOPOULOU, Constantina , SUBRAMANYAM, Ravi , WU, Donghui , MORGAN, Andre, M. , WANG, Qin , TAMBS, Gary, Edward , BARNES, Virginia, Monsul
发明人： ROBINSON, Richard, Scott , SULLIVAN, Richard, J. , PRENCIPE, Michael , VAN RYCKE, Isabelle , LOVELL, Richard , KOHLI, Rajnish , LEITE, Sergio , SIMON, Eric, A. , SANTARPIA, Ralph, Peter, III , CUMMINS, Diane , MELLO, Sarita, V. , CHOPRA, Suman, K. , DEPIERRO, Karen , ZAIDEL, Lynette , CHRISTOPOULOU, Constantina , SUBRAMANYAM, Ravi , WU, Donghui , MORGAN, Andre, M. , WANG, Qin , TAMBS, Gary, Edward , BARNES, Virginia, Monsul
IPC分类号： A61K8/44 , A61Q11/00 , A61K31/198 , A61P1/02
CPC分类号： A61K8/44 , A61K31/198 , A61Q11/00
摘要： The invention includes methods of cleaning an oral surface, maintaining oral health and/or increasing oral health. Such methods encompass contacting an oral surface with a primary oral care composition at least once daily, contacting the oral surface with a periodic oral care maintenance composition at least once monthly, wherein the periodic oral care maintenance composition comprises a basic amino acid, in free or salt form and optionally contacting the oral surface with a periodic oral care cleaning composition at least once monthly. The periodic oral care cleaning compositions suitable for use in the method comprise an abrasive system.
摘要翻译：本发明包括清洁口腔表面，维持口腔健康和/或增加口腔健康的方法。这样的方法包括每天至少一次使口腔表面与主要口腔护理组合物接触，使口腔表面与定期的口腔护理维持组合物每月至少一次接触，其中定期口腔护理维持组合物包含游离或任选地使口腔表面与定期的口腔护理清洁组合物每月至少一次接触。适用于该方法的定期口腔护理清洁组合物包括研磨系统。

2. 发明申请

WO1997046462A1 CODISPENSING OF PHYSICALLY SEGREGATED DENTIFRICES AT CONSISTANT RATIOS 审中-公开
标题翻译：按照一致性比例计算物理分离的牙龈卟啉症
公开(公告)号：WO1997046462A1
公开(公告)日：1997-12-11
申请号：PCT/US1997008622
申请日：1997-05-21
申请人： COLGATE-PALMOLIVE COMPANY
发明人： COLGATE-PALMOLIVE COMPANY , MASTERS, James, G. , SULLIVAN, Richard, J. , PRENCIPE, Michael , CONNAN, A., Patrick
IPC分类号： B65D35/22
CPC分类号： B65D81/325 , B65D35/22
摘要： A method is disclosed for the coextrusion in controlled amounts of at least two dentifrice components stored and physically segregated in a multicompartmented collapsible dispenser provided with a partition which divides the interior volume of the container into separate compartments, the partition being moveable in response to a pressure differential developed thereacross upon the application of Compressive Force to the sidewalls, the individuals dentifrice components containing ingredients which interact when mixed, the dispenser sidewalls being formed of a resilient plastic material which is deflected upon the application thereto of a Deflective Force of about 1.0 or greater pounds, the dentifrice compnents being formulated to be equally extrudible at substantially equivalent compressive forces. When the dispenser sidewalls are compressed, there is extruded a single-banded unmixed multilayer stream of the components containing the reactive ingredients at ratios predetermined to provide optimum levels for interaction between the reacted ingredients when the extruded components are mixed in the oral cavity.
摘要翻译：公开了一种用于将受控量的至少两种洁齿剂组分共挤出的方法，所述至少两种洁齿剂组分储存和物理分离在具有将容器的内部容积分成独立隔室的分隔壁的多室压缩分配器中，所述隔板响应于压力而可移动在压缩力施加到侧壁上时，各种微生物发生变化，所述个体含有混合物相互作用的成分的洁齿剂组分，分配器侧壁由弹性塑料材料形成，弹性塑料材料在应用时偏转约为1.0或更大的防反射力磅，配方的洁牙剂组分以基本相当的压缩力同等挤出。当分配器侧壁被压缩时，挤出含有预定比例的反应性成分的组分的单条未混合多层流，以便当将挤出的组分混合在口腔中时，为反应成分之间的相互作用提供最佳水平。

3. 发明申请

WO2004012693A2 DENTINAL DESENSITIZING DENTIFRICE PROVIDING ENHANCED REMINERALIZATION AND ANTICARIES BENEFITS 审中-公开
标题翻译：提供增强渗透性和抗菌性的DENTINAL DESENSITIZING DENTIFRICE
公开(公告)号：WO2004012693A2
公开(公告)日：2004-02-12
申请号：PCT/US2003/024526
申请日：2003-08-04
申请人： COLGATE-PALMOLIVE COMPANY
发明人： FISHER, Steven, W. , JOZIAK, Marilou, T. , SULLIVAN, Richard, J. , STRANICK, Michael, A. , HEU, Rodman, T.
IPC分类号： A61K7/18
CPC分类号： A61K8/24 , A61K8/19 , A61K8/21 , A61K2800/52 , A61Q11/00
摘要： A dental composition which eliminates or substantially reduces the discomfort and pain associated with dentinal hypersensitivity and exhibits enhanced anticaries and remineralization benefits which composition contains a fluoride ion and a potassium ion releasable salt and has a pH in the range of about 8 to about 9.9, the pH being buffered with phosphate salt.
摘要翻译：牙科组合物消除或基本上减少与牙质过敏相关的不适和疼痛，并且表现出增强的防龋和再矿化益处，该组合物含有氟离子和钾离子可释放盐，并且pH在约8至约9.9的范围内， pH用磷酸盐缓冲。

4. 发明申请

WO1997046463A1 UNIFORM DISPENSING MULTICHAMBER TUBULAR CONTAINERS 审中-公开
标题翻译：均质分配多孔管状容器
公开(公告)号：WO1997046463A1
公开(公告)日：1997-12-11
申请号：PCT/US1997008623
申请日：1997-05-21
申请人： COLGATE-PALMOLIVE COMPANY
发明人： COLGATE-PALMOLIVE COMPANY , CONNAN, Patrick, A. , MACK, Robert , MUSTAFA, Ramon, Armando, Mejia , MASTERS, James, G. , SULLIVAN, Richard, J. , PRENCIPE, Michael
IPC分类号： B65D35/22
CPC分类号： B65D35/22 , B65D81/325
摘要： A multichamber container must have certain characteristics in order to uniformly dispense the contents of each chamber from the container. The outer wall of the container and the inner divider web walls must have certain characteristics. The inner divider web walls must be highly flexible while the outer container wall must be less flexible. The Deflective Force for the outer wall must be greater than the Deflective Force for the web walls. In addition, to alleviate the problem of suckback of air into the container chambers, the outer wall should exhibit a specific Retention Index. This is a measure of the outer wall to remain deflected after the removal of the deflecting force. The inner divider web wall will have a lower Retention Index than the outer wall. By the proper selection of outer wall and web walls, there can be uniform dispensing from the dispenser.
摘要翻译：多室容器必须具有某些特性，以便从容器均匀地分配每个室的内容物。容器的外壁和内隔板腹壁必须具有一定的特性。内部分隔件网壁必须是高度柔性的，而外部容器壁必须较不灵活。外壁的防反射力必须大于网壁的防反射力。此外，为了减轻将空气吸回到容器室中的问题，外壁应该具有特定的保持指数。这是在去除偏转力之后保持偏转的外壁的量度。内隔板腹壁具有比外壁更低的保持力指数。通过适当选择外壁和腹壁，可以从分配器中均匀分配。

5. 发明申请

WO2009099455A1 ORAL CARE PRODUCT AND METHODS OF USE AND MANUFACTURE THEREOF 审中-公开
标题翻译：口腔护理产品及其使用和制造方法
公开(公告)号：WO2009099455A1
公开(公告)日：2009-08-13
申请号：PCT/US2008/058715
申请日：2008-03-28
申请人： COLGATE-PALMOLIVE COMPANY , PRENCIPE, Michael , CUMMINS, Diane , SUBRAMANYAM, Ravi , SULLIVAN, Richard, J. , SANTARPIA, Ralph, Peter , MELLO, Sarita, V. , ZAIDEL, Lynette , CHOPRA, Suman, K. , WANG, Qin , TAMBS, Gary, Edward , BARNES, Virginia, Monsul , WU, Donghui , MORGAN, Andre, M. , KOHLI, Rajnish , ROBINSON, Richard, Scott , LEITE, Sergio , SIMON, Eric, A.
发明人： PRENCIPE, Michael , CUMMINS, Diane , SUBRAMANYAM, Ravi , SULLIVAN, Richard, J. , SANTARPIA, Ralph, Peter , MELLO, Sarita, V. , ZAIDEL, Lynette , CHOPRA, Suman, K. , WANG, Qin , TAMBS, Gary, Edward , BARNES, Virginia, Monsul , WU, Donghui , MORGAN, Andre, M. , KOHLI, Rajnish , ROBINSON, Richard, Scott , LEITE, Sergio , SIMON, Eric, A.
IPC分类号： A61K8/44 , A61K8/46 , A61Q11/00 , A61K31/198 , A61P1/02
CPC分类号： A61K8/44 , A61K8/19 , A61K8/21 , A61K8/24 , A61K31/198 , A61Q11/00
摘要： This invention relates to oral care compositions comprising an effective amount of a basic amino acid in free or salt form, together with an anionic surfactant, and to methods of using and of making such compositions.
摘要翻译：本发明涉及包含游离或盐形式的有效量的碱性氨基酸以及阴离子表面活性剂的口腔护理组合物，以及使用和制备这些组合物的方法。

6. 发明申请

WO2009099452A1 ORAL CARE PRODUCT AND METHODS OF USE AND MANUFACTURE THEREOF 审中-公开
标题翻译：口腔护理产品及其使用和制造方法
公开(公告)号：WO2009099452A1
公开(公告)日：2009-08-13
申请号：PCT/US2008/058679
申请日：2008-03-28
申请人： COLGATE-PALMOLIVE COMPANY , PRENCIPE, Michael , CUMMINS, Diane , ROBINSON, Richard, Scott , MELLO, Sarita, V. , SULLIVAN, Richard, J. , CHOPRA, Suman, K. , DEPIERRO, Karen , ZAIDEL, Lynette , CHRISTOPOULOU, Constantina , SUBRAMANYAM, Ravi , WU, Donghui , MORGAN, Andre, M. , SANTARPIA III, Ralph, Peter , WANG, Qin , TAMBS, Gary, Edward , KOHLI, Rajnish , BARNES, Virginia, Monsul , LEITE, Sergio , SIMON, Eric, A.
发明人： PRENCIPE, Michael , CUMMINS, Diane , ROBINSON, Richard, Scott , MELLO, Sarita, V. , SULLIVAN, Richard, J. , CHOPRA, Suman, K. , DEPIERRO, Karen , ZAIDEL, Lynette , CHRISTOPOULOU, Constantina , SUBRAMANYAM, Ravi , WU, Donghui , MORGAN, Andre, M. , SANTARPIA III, Ralph, Peter , WANG, Qin , TAMBS, Gary, Edward , KOHLI, Rajnish , BARNES, Virginia, Monsul , LEITE, Sergio , SIMON, Eric, A.
IPC分类号： A61K8/44 , A61K8/25 , A61Q11/00 , A61K31/198 , A61P1/02
CPC分类号： A61K8/44 , A61K8/25 , A61K31/198 , A61Q11/00
摘要： This invention relates to oral care compositions comprising a basic amino acid or salt thereof, and a small particle fraction; and to methods of using and of making these compositions.
摘要翻译：本发明涉及包含碱性氨基酸或其盐和小颗粒级分的口腔护理组合物; 以及使用和制备这些组合物的方法。

7. 发明申请

WO2009099451A1 ARGININE SALTS AND THEIR USES FOR THE TREATMENT OF ILLNESSES IN THE ORAL CAVITY 审中-公开
标题翻译： ARGININE SALTS及其用于治疗口腔溃疡的用途
公开(公告)号：WO2009099451A1
公开(公告)日：2009-08-13
申请号：PCT/US2008/058658
申请日：2008-03-28
申请人： COLGATE-PALMOLIVE COMPANY , PRENCIPE, Michael , XU, Guofeng , SUBRAMANYAM, Ravi , WU, Donghui , CUMMINS, Diane , SULLIVAN, Richard, J. , SANTARPIA, Ralph, Peter , MELLO, Sarita, V. , ZAIDEL, Lynette , CHOPRA, Suman, K. , WANG, Qin , TAMBS, Gary, Edward , BARNES, Virginia, Monsul , MORGAN, Andre, M. , KOHLI, Rajnish , ROBINSON, Richard, Scott , LEITE, Sergio , SIMON, Eric, A.
发明人： PRENCIPE, Michael , XU, Guofeng , SUBRAMANYAM, Ravi , WU, Donghui , CUMMINS, Diane , SULLIVAN, Richard, J. , SANTARPIA, Ralph, Peter , MELLO, Sarita, V. , ZAIDEL, Lynette , CHOPRA, Suman, K. , WANG, Qin , TAMBS, Gary, Edward , BARNES, Virginia, Monsul , MORGAN, Andre, M. , KOHLI, Rajnish , ROBINSON, Richard, Scott , LEITE, Sergio , SIMON, Eric, A.
IPC分类号： A61K8/44 , A61Q11/00 , A61K31/198 , A61P1/02
CPC分类号： A61K8/44 , A61K8/463 , A61K8/55 , A61K8/8164 , A61K31/198 , A61Q11/00
摘要： The invention relates to novel arginine salts, compositions comprising them, and their uses.
摘要翻译：本发明涉及新颖的精氨酸盐，包含它们的组合物及其用途。

8. 发明申请

WO2005006872A1 CHEWABLE ANTIPLAQUE CONFECTIONERY DENTAL COMPOSITION 审中-公开
标题翻译：可咀嚼的防腐剂牙科组合物
公开(公告)号：WO2005006872A1
公开(公告)日：2005-01-27
申请号：PCT/US2004/021873
申请日：2004-07-09
申请人： COLGATE-PALMOLIVE COMPANY , DU-THUMM, Laurence , SZELES, Lori, H. , SULLIVAN, Richard, J. , MASTERS, James G. , ROBINSON, Richard, S.
发明人： DU-THUMM, Laurence , SZELES, Lori, H. , SULLIVAN, Richard, J. , MASTERS, James G. , ROBINSON, Richard, S.
IPC分类号： A23G3/00
CPC分类号： A23G3/366 , A23G4/123 , A61K8/60 , A61K8/64 , A61K8/66 , A61Q11/00 , Y10S514/835
摘要： A chewable confectionery dental composition delivering to the mouth a unit dose of a plaque reducing enzyme the composition comprising an enzyme and a non-cariogenic sweetener, the enzyme being incorporated in the composition at a temperature less than about 80°C.
摘要翻译：一种咀嚼糖食牙科组合物，其向所述口部输送单位剂量的斑块还原酶，所述组合物包含酶和非致龋性甜味剂，所述酶在小于约80℃的温度下加入到所述组合物中。

9. 发明申请

WO2015084321A1 ORAL CARE COMPOSITIONS 审中-公开
标题翻译：口腔护理组合物
公开(公告)号：WO2015084321A1
公开(公告)日：2015-06-11
申请号：PCT/US2013/072755
申请日：2013-12-03
申请人： COLGATE-PALMOLIVE COMPANY
发明人： SANTARPIA, Ralph, Peter, III , SULLIVAN, Richard, J. , PETROU, Irene , JOSIAS, Wilbens , ROBINSON, Richard, S.
IPC分类号： A61K8/24 , A61K8/25 , A61K8/44 , A61Q11/00 , A61K8/21
CPC分类号： A61K8/86 , A61K8/21 , A61K8/24 , A61K8/25 , A61K8/29 , A61K8/44 , A61K8/463 , A61K2800/28 , A61K2800/43 , A61K2800/48 , A61K2800/5922 , A61Q11/00
摘要： The application discloses dentifrice compositions comprising arginine together with fluoride, phosphate and pyrophosphate salts, in a dentifrice base with a calcium-free silica abrasive, which compositions provide enhanced remineralization, together with methods of using and of making these compositions.
摘要翻译：本申请公开了含有精氨酸以及氟化物，磷酸盐和焦磷酸盐的洁齿剂组合物，其与无钙二氧化硅研磨剂在洁齿剂基质中，该组合物提供了增强的再矿化，以及使用和制备这些组合物的方法。

10. 发明申请

WO2012023936A1 ORAL CARE PRODUCT AND METHODS OF USE AND MANUFACTURE THEREOF 审中-公开
标题翻译：口腔护理产品及其使用和制造方法
公开(公告)号：WO2012023936A1
公开(公告)日：2012-02-23
申请号：PCT/US2010/045894
申请日：2010-08-18
申请人： COLGATE-PALMOLIVE COMPANY , ROBINSON, Richard, Scott , SULLIVAN, Richard, J. , KOHLI, Rajnish
发明人： ROBINSON, Richard, Scott , SULLIVAN, Richard, J. , KOHLI, Rajnish
IPC分类号： A61K8/19 , A61K8/44 , A61Q11/00
CPC分类号： A61K8/44 , A61K8/19 , A61K8/36 , A61Q11/00
摘要： Described herein, are compositions comprising an effective amount of a basic amino acid in free or salt form, and a water soluble strontium salt; and methods of making and using the same.
摘要翻译：本文描述的是包含有效量的游离或盐形式的碱性氨基酸和水溶性锶盐的组合物; 以及制作和使用它们的方法。

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