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1. 发明申请

US20140363859A1 RECOMBINANT MICROORGANISM HAVING IMPROVED PUTRESCINE PRODUCING ABILITY AND METHOD FOR PRODUCING PUTRESCINE BY USING SAME 有权
标题翻译：具有改进的PUTRESCINE生产能力的重组微生物和使用它们生产PUTRESCINE的方法
公开(公告)号：US20140363859A1
公开(公告)日：2014-12-11
申请号：US14373265
申请日：2013-01-21
申请人： CJ CHEILJEDANG CORPORATION
发明人： Kyoung Min Lee , Seon Hye Kim , Hye Won Um , Min Sun Kang , Su Jin Choi , Hee Kyoung Jung , Sung Hoo Jhon , Hongxian Li , Won Sik Gwak , Chong Ho Lee , Young Lyeol Yang
IPC分类号： C12N15/77 , C12P13/00
CPC分类号： C12N15/77 , C12N15/52 , C12P13/001
摘要： The present invention relates to a recombinant microorganism having enhanced ability to produce putrescine at high yield, wherein the activity of NCgl0101 is weakened in a microorganism of genus Corynebacterium that has been modified to produce putrescine, and a method for producing putrescine using the same.
摘要翻译：本发明涉及一种能够以高产率产生腐胺的能力增强的重组微生物，其中在已经被修饰以产生腐胺的棒状杆菌属的微生物中，NCgl0101的活性被削弱，以及使用其的腐胺的制备方法。

2. 发明申请

US20140017205A1 BACTERIOPHAGE AND ANTIBACTERIAL COMPOSITION COMPRISING THE SAME 有权
标题翻译：含有其的细菌和抗菌组合物
公开(公告)号：US20140017205A1
公开(公告)日：2014-01-16
申请号：US13621688
申请日：2012-09-17
申请人： CJ CHEILJEDANG CORPORATION
发明人： Soo An Shin , Min Tae Park , Hyang Choi , Young Wook Cho , In Hye Kang , Su Jin Choi
IPC分类号： C12N7/00
CPC分类号： C12N7/00 , A01N63/00 , A61K35/76 , C12N2795/10311 , C12N2795/10321 , C12N2795/10331 , C12N2795/10332 , C12N2795/10351 , C12N2795/10371
摘要： Disclosed herein is a novel bacteriophage which has specific bactericidal activity against one or more Salmonella bacteria selected from the group consisting of Salmonella enteritidis, Salmonella typhimurium, Salmonella gallinarum, and Salmonella pullorum without affecting beneficial bacteria, in addition to showing excellent tolerance to acid, heat and desiccation. The novel bacteriophage of the present invention can be widely used as an active ingredient for therapeutic agents, animal feeds or drinking water, cleaners and sanitizers for preventing and treating the infectious diseases caused by Salmonella enteritidis, Salmonella typhimurium, Salmonella gallinarum or Salmonella pullorum including salmonellosis, Salmonella food poisoning, Fowl Typhoid, and Pullorum disease or for controlling the Salmonella bacteria. The present invention also provides important insights into prevention and control strategies against Salmonella infection and suggests that the use of bacteriophage can be a novel, safe, and effectively plausible alternative to antibiotics for the prevention of Salmonella infection in poultry.
摘要翻译：本文公开了一种新型噬菌体，其对一种或多种选自肠炎沙门氏菌，鼠伤寒沙门氏菌，沙门氏菌和沙门氏菌的沙门菌细菌具有特异杀菌活性，而不影响有益细菌，除了显示对酸，热的良好耐受性和干燥。本发明的新型噬菌体可广泛用作治疗剂，动物饲料或饮用水，清洁剂和消毒剂，用于预防和治疗由肠炎沙门氏菌，鼠伤寒沙门氏菌，沙门氏菌或沙门氏菌包括沙门氏菌病引起的感染性疾病的活性成分，沙门氏菌食物中毒，家禽伤寒和Pullorum病或用于控制沙门氏菌。本发明还提供了针对沙门氏菌感染的预防和控制策略的重要见解，并表明使用噬菌体可以是预防家禽沙门氏菌感染的抗生素的新颖，安全和有效的合理替代方法。

3. 发明授权

US09593353B2 Microorganisms for production of O-succinylhomoserine and method for production of O-succinylhomoserine using the same 有权
标题翻译：用于生产O-琥珀酰高丝氨酸的微生物及使用其的O-琥珀酰高丝氨酸的生产方法
公开(公告)号：US09593353B2
公开(公告)日：2017-03-14
申请号：US15031703
申请日：2014-10-22
申请人： CJ CHEILJEDANG CORPORATION
发明人： Su Jin Choi , So Young Kim , Chang Il Seo , Yong Uk Shin , Young Lyeol Yang , Hye Won Um , Hye Min Park , Sung Hoo Jhon , Byung Hoon Jung
IPC分类号： C12P13/06 , C12N9/10
CPC分类号： C12P13/06 , C12N9/1029 , C12Y203/01046 , Y02P20/52
摘要： The present invention relates to a polypeptide having a resistant to feedback inhibition by methionine and an activity of homoserine O-succinyltransferase, a O-succinyl homoserine-producing microorganism expressing the polypeptide, and a method for producing O-succinyl homoserine using the same.
摘要翻译：本发明涉及具有抗甲硫氨酸反馈抑制和高丝氨酸O-琥珀酰基转移酶的活性的多肽，表达该多肽的产生O-琥珀酰高丝氨酸的微生物的活性，以及使用该多肽产生O-琥珀酰高丝氨酸的方法。

4. 发明申请

US20150104838A1 RECOMBINANT MICROORGANISM HAVING IMPROVED PUTRESCINE PRODUCING ABILITY AND METHOD FOR PRODUCING PUTRESCINE BY USING SAME 有权
标题翻译：具有改进的PUTRESCINE生产能力的重组微生物和使用它们生产PUTRESCINE的方法
公开(公告)号：US20150104838A1
公开(公告)日：2015-04-16
申请号：US14372000
申请日：2013-01-11
申请人： CJ CHEILJEDANG CORPORATION
发明人： Su Jin Choi , Hyang Choi , Min Sun Kang , Sung Hoo Jhon , Kyoung Min Lee , Hye Won Um , Young Lyeol Yang
IPC分类号： C12P13/00
CPC分类号： C12P13/001 , C12N9/1029 , C12N15/1093
摘要： The present invention relates to a recombinant microorganism having enhanced ability of producing putrescine at high yield, which is generated by weakening the activity of NCgl1469 in a microorganism of Corynebacterium genus that is modified to produce putrescine, and a method for producing putrescine using the same.
摘要翻译：本发明涉及通过削弱经修饰以产生腐胺的棒状杆菌属微生物中的NCgl1469的活性而产生的以高产率产生腐胺的能力增强的重组微生物，以及使用其制造腐胺的方法。

5. 发明授权

US11292944B2 Adhesive composition and method for preparing same 有权
公开(公告)号：US11292944B2
公开(公告)日：2022-04-05
申请号：US16496613
申请日：2018-03-21
申请人： CJ CHEILJEDANG CORPORATION
发明人： Ji Ho Hwang , Jun Ok Moon , Young Lyeol Yang , Chang Suk Lee , Sang Gwon Moon , Su Jin Choi
IPC分类号： C09J11/06 , C09J4/00
摘要： Provided is an adhesive composition including lysine, citric acid, and water, wherein the lysine and the citric acid are present in the form of an aqueous solution of a salt such that precipitates are not formed in the aqueous solution. In addition, provided is a method of preparing an adhesive composition including mixing lysine, citric acid, and water to thereby form a mixture of the lysine, the citric acid, and the water, and stirring the mixture at a temperature of 80° C. or less, wherein amounts of the lysine, the citric acid, and the water are adjusted such that precipitates of the lysine and the citric acid do not form in the adhesive composition.

6. 发明授权

US11254845B2 Adhesive composition and method for preparing same 有权
公开(公告)号：US11254845B2
公开(公告)日：2022-02-22
申请号：US16496623
申请日：2018-03-21
申请人： CJ CHEILJEDANG CORPORATION
发明人： Ji Ho Hwang , Jun Ok Moon , Young Lyeol Yang , Chang Suk Lee , Sang Gwon Moon , Su Jin Choi
IPC分类号： C09J11/06 , C09J4/00
摘要： Provided is an adhesive composition including lysine, itaconic acid, and water, wherein the lysine and the itaconic acid are present in the form of an aqueous solution of a salt such that precipitates are not formed in the aqueous solution. In addition, provided is a method of preparing an adhesive composition including mixing lysine, itaconic acid, and water to thereby form a mixture of the lysine, the citric acid, and the water, and stirring the mixture at a temperature of 80° C. or less, wherein amounts of the lysine, the itaconic acid, and the water are adjusted such that precipitates of the lysine and the itaconic acid do not form in the adhesive composition.

7. 发明授权

US10750762B2 Bio-based N-acetyl-L-methionine and use thereof 有权
公开(公告)号：US10750762B2
公开(公告)日：2020-08-25
申请号：US15766325
申请日：2016-10-14
申请人： CJ Cheiljedang Corporation
发明人： Jin Woo Jeon , Jun Ok Moon , Jin Seung Park , Su Jin Choi , Kuk Ki Hong , Jeong Hyun Kim , Hye Min Park , So Yeon Hong
IPC分类号： A23K20/142 , C12P13/12 , A23K50/10 , A23K10/12 , A23K10/14 , A23K10/18 , A61K31/198
摘要： A bio-based N-acetyl-L-methionine and a preparation method thereof, a feed additive containing the N-acetyl-L-methionine, a feed composition containing the feed additive, and a method for raising animals which includes feeding a feed additive containing the N-acetyl-L-methionine or a feed composition containing the feed additive to animals.

8. 发明授权

US09677099B2 Recombinant microorganisms with an improved productivity of putrescine and method for producing putrescine using the same 有权
公开(公告)号：US09677099B2
公开(公告)日：2017-06-13
申请号：US14372000
申请日：2013-01-11
申请人： CJ CHEILJEDANG CORPORATION
发明人： Su Jin Choi , Hyang Choi , Min Sun Kang , Sung Hoo Jhon , Kyoung Min Lee , Hye Won Um , Young Lyeol Yang
IPC分类号： C12P13/00 , C12N1/21 , C12N9/10 , C12N15/10
CPC分类号： C12P13/001 , C12N9/1029 , C12N15/1093
摘要： The present invention relates to a recombinant microorganism having enhanced ability of producing putrescine at high yield, which is generated by weakening the activity of NCgl1469 in a microorganism of Corynebacterium genus that is modified to produce putrescine, and a method for producing putrescine using the same.

9. 发明授权

US12037610B2 Methods for preparing N-acetyl-L-methionine 有权
公开(公告)号：US12037610B2
公开(公告)日：2024-07-16
申请号：US17452565
申请日：2021-10-27
申请人： CJ CHEILJEDANG CORPORATION
发明人： So Yeon Hong , Jinseung Park , Hye Min Park , Su Jin Choi , Jun Ok Moon , Sung Gun Lee , Jinwoo Jeon
IPC分类号： C12N9/10 , C12N15/63 , C12N15/70 , C12N15/77 , C12N15/81 , C12P13/12
CPC分类号： C12N9/1025 , C12N9/10 , C12N15/63 , C12N15/70 , C12N15/77 , C12N15/81 , C12P13/12 , C12Y203/01001
摘要： The present disclosure relates to a polypeptide having an acyltransferase activity or a microorganism including the same; a composition for preparing N-acetyl-L-methionine, the composition including the polypeptide or microorganism; and a method of preparing N-acetyl-L-methionine using the polypeptide or microorganism. Further, the present disclosure relates to a polynucleotide encoding the polypeptide and an expression vector including the polynucleotide. Since the microorganism including a novel acyltransferase according to the present disclosure has enhanced acyltransferase activity, this microorganism can be efficiently used for producing N-acetyl-L-methionine by acetylating L-methionine.

10. 发明授权

US10570429B2 O-succinylhomoserine producing microorganism and method for producing O-succinylhomoserine using same 有权
公开(公告)号：US10570429B2
公开(公告)日：2020-02-25
申请号：US15303196
申请日：2015-01-22
申请人： CJ CHEILJEDANG CORPORATION
发明人： Su Jin Choi , Kuk Ki Hong , Young Lyeol Yang , Min Sun Kang , Hye Min Park , Gyuhyeon Song , Jong Hyun Yoon
IPC分类号： C12P13/06 , C12N15/70 , C12N15/52
摘要： Provided are a microorganism of the genus Escherichia for producing O-succinylhomoserine and a method for producing O-succinylhomoserine using the same.

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