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1. 发明申请

WO2007048645A3 PROTECTION OF OXIDIZABLE AGENTS 审中-公开
标题翻译：氧化剂的保护
公开(公告)号：WO2007048645A3
公开(公告)日：2008-01-17
申请号：PCT/EP2006063421
申请日：2006-06-21
申请人： CIBA SC HOLDING AG , MONGIAT SEBASTIEN , BASCHONG WERNER , HERZOG BERND
发明人： MONGIAT SEBASTIEN , BASCHONG WERNER , HERZOG BERND
IPC分类号： A61K31/05 , A61K31/222 , A61K31/255 , A61K31/34 , A61K31/445 , A61P17/00 , A61P17/16 , A61P27/14 , A61P29/00 , A61P43/00
CPC分类号： A61K31/05 , A61K8/11 , A61K8/14 , A61K8/347 , A61K8/37 , A61K8/375 , A61K8/42 , A61K8/46 , A61K8/466 , A61K8/4926 , A61K8/4966 , A61K8/4973 , A61K8/553 , A61K8/671 , A61K8/676 , A61K31/222 , A61K31/255 , A61K31/34 , A61K31/445 , A61K2800/412 , A61K2800/413 , A61K2800/522 , A61Q1/02 , A61Q5/02 , A61Q11/00 , A61Q17/04 , A61Q19/00 , A61Q19/10
摘要： Formulations for cosmetical or pharmaceutical use contain an antioxidant in encapsulated form and a cosmetically or pharmaceutically acceptable carrier. The antioxidant is selected from carbon bridged hindered phenoles, ester bridged hindered phenoles, amide bridged hindered phenoles, lactones of hindered phenoles, sterically hindered oxylamines and sterically hindered hydroxylamines. The encapsulated antioxidant is of high activity and suitable to protect a further active ingredient, e.g. oxidizable natural substances, vitamins, fragrances, and extracts from plants fungi, algae or animals, from premature degradation, especially when coencapsulated together with the ingredient. The formulations are useful inter alia for the preparation of a cosmetical or pharmaceutical skin care or skin delivery formulation, injectable solution, infusion solution, eye drop, drinking solution, a dietary or enriched food, an oral care formulation, drinking gargles, in-halants, or as a food additive.
摘要翻译：化妆品或药物用途的制剂含有包封形式的抗氧化剂和化妆品或药学上可接受的载体。抗氧化剂选自碳桥接的受阻酚，酯桥接的受阻酚，酰胺桥接的受阻酚，受阻酚的内酯，空间位阻的羟胺和空间位阻羟胺。包封的抗氧化剂具有高活性并且适合于保护另外的活性成分，例如，可氧化的天然物质，维生素，香料，以及来自植物真菌，藻类或动物的提取物，过早降解，特别是当与成分一起胶囊时。该制剂尤其用于制备美容或药物皮肤护理或皮肤递送制剂，可注射溶液，输注溶液，滴眼剂，饮用溶液，饮食或富含食物，口腔护理制剂，饮用漱口剂，漱口剂，或作为食品添加剂。

2. 发明申请

WO2007062995A3 GLUCAN COMPOSITIONS 审中-公开
标题翻译：葡聚糖组合物
公开(公告)号：WO2007062995A3
公开(公告)日：2007-08-23
申请号：PCT/EP2006068645
申请日：2006-11-20
申请人： CIBA SC HOLDING AG , BASCHONG WERNER , MONGIAT SEBASTIEN , OCHS DIETMAR
发明人： BASCHONG WERNER , MONGIAT SEBASTIEN , OCHS DIETMAR
IPC分类号： A61Q11/00 , A61K8/34 , A61K8/365 , A61K8/73 , A61K8/99 , A61K9/00 , A61K31/716 , A61Q19/08
CPC分类号： A61Q11/00 , A61K8/345 , A61K8/347 , A61K8/365 , A61K8/43 , A61K8/73 , A61K31/716 , A61Q1/10 , A61Q1/14 , A61Q5/02 , A61Q5/12 , A61Q19/00 , A61Q19/08
摘要： A cosmetic or pharmaceutical composition is provided comprising: a) 0.001 to less than 0.2 % by weight, based on the weight of the total composition, of a scleroglucan having a mean molecular weight of 1x10 6 to 12x10 6 ; b) a cosmetically or pharmaceutically acceptable carrier; and, optionally, c) lactic acid, a lactate and/or pentanediol. The composition shows advantageous effects, such as moisturization of skin or mucosa, and has an antiaging and revitalizing effect on the skin. When combined with a certain bactericide as explained in claim 1 , compositions containing native polysaccharides of the glucan class in general, especially of the scleroglucan as of component a), are well suitable to reduce the number of bacteria in mucosal or oral environments and minimise adhesion, while retaining a pleasant feeling on the mucosa or gingiva. Plaque thus can be efficiently prevented or removed.
摘要翻译：提供了化妆品或药物组合物，其包含：a）基于总组合物的重量，0.001至小于0.2重量％的平均分子量为1×10 6至12×10 6的硬葡聚糖， SUP> 6 ; b）美容或药学上可接受的载体; 和任选的c）乳酸，乳酸酯和/或戊二醇。该组合物显示出有益的效果，例如皮肤或粘膜的滋润，并且对皮肤具有抗衰老和再生作用。当与权利要求1所述的某种杀菌剂结合时，通常含有葡聚糖类天然多糖，特别是组分a）的硬葡聚糖的组合物非常适合于减少粘膜或口腔环境中细菌的数量，并使粘附最小化同时在粘膜或牙龈上保持愉快的感觉。因此可以有效地防止或移除斑块。

3. 发明申请

WO2005013931B1 USE OF HALOGENATED HYDROXYDIPHENYL ETHER COMPOUNDS FOR THE TREATMENT OF THE SKIN 审中-公开
标题翻译：卤化羟基二苯基醚化合物用于治疗皮肤的用途
公开(公告)号：WO2005013931B1
公开(公告)日：2005-04-07
申请号：PCT/EP2004051379
申请日：2004-07-07
申请人： CIBA SC HOLDING AG , BASCHONG WERNER , SCHNYDER MARCEL
发明人： BASCHONG WERNER , SCHNYDER MARCEL
IPC分类号： A61K8/34 , A61Q19/02 , A61K7/48
CPC分类号： A61Q19/02 , A61K8/347
摘要： The use of hydroxydiphenyl ether compounds of formula (I), wherein R1, R2 and R3 are each independently of the others hydrogen; hydroxy; C1-C20alkyl; hydroxy-substituted C1-C20alkyl; C5-C7cycloalkyl; C1-C20alkoxy; C1-C6alkylcarbonyl; phenyl; or phenyl-C1-C3alkyl; R4 is hydrogen, C1-C20alkyl; hydroxy-substituted C1-C20alkyl; C5-C7cycloalkyl; hydroxy; formyl; acetonyl; allyl; carboxy; carboxy-C1-C3alkyl; carboxyallyl; C2-C20alkenyl; C1-C6alkylcarbonyl; C1-C3alkylcarbonyl-C1-C3alkyl; phenyl; or phenyl-C1-C3alkyl; and R5 is hydrogen; C1-C20alkoxy; or C1-C6alkylcarbonyl; as melanogenesis inhibitors and for lightening the skin.
摘要翻译：使用式（I）的羟基二苯醚化合物，其中R 1，R 2和R 3各自独立地为氢; 羟基; C1-C20烷基; 羟基取代的C 1 -C 20烷基; C5-C7环烷基; C1-C20alkoxy; C1-C6alkylcarbonyl; 苯基; 或苯基-C 1 -C 3烷基; R4是氢，C1-C20烷基; 羟基取代的C 1 -C 20烷基; C5-C7环烷基; 羟基; 甲酰基; 丙酮; 烯; 羧基; 羧基C1-C3烷基; carboxyallyl; C2-C20alkenyl; C1-C6alkylcarbonyl; C1-C3alkylcarbonyl-C1-C3烷基; 苯基; 或苯基-C 1 -C 3烷基; 并且R5是氢; C1-C20alkoxy; 或C 1 -C 6烷基羰基; 作为黑素生成抑制剂和增亮皮肤。

4. 发明申请

WO0151013A3 USE OF MICROBIALLY ENCAPSULATED MATERIALS IN COSMETIC END FORMULATIONS 审中-公开
标题翻译：在化妆品末端配方中使用微胶囊材料
公开(公告)号：WO0151013A3
公开(公告)日：2002-01-31
申请号：PCT/EP0100051
申请日：2001-01-04
申请人： CIBA SC HOLDING AG , BASCHONG WERNER , HUEGLIN DIETMAR
发明人： BASCHONG WERNER , HUEGLIN DIETMAR
IPC分类号： C12N1/16 , A61K8/00 , A61K8/04 , A61K8/06 , A61K8/11 , A61K8/33 , A61K8/34 , A61K8/67 , A61K8/69 , A61K8/92 , A61K8/96 , A61K8/97 , A61K8/98 , A61K8/99 , A61Q1/02 , A61Q3/00 , A61Q3/02 , A61Q5/00 , A61Q5/02 , A61Q9/02 , A61Q11/00 , A61Q13/00 , A61Q15/00 , A61Q17/02 , A61Q17/04 , A61Q19/00 , A61Q19/10 , A61K7/48 , A61K7/00
CPC分类号： A61Q19/10 , A61K8/046 , A61K8/11 , A61K8/347 , A61K8/671 , A61K8/676 , A61K8/678 , A61K8/69 , A61K8/922 , A61K8/9706 , A61K8/99 , A61K2800/412 , A61Q1/02 , A61Q3/00 , A61Q5/00 , A61Q5/02 , A61Q9/02 , A61Q11/00 , A61Q13/00 , A61Q15/00 , A61Q17/00 , A61Q17/02 , A61Q17/04 , A61Q19/00 , A61Q19/002 , A61Q19/004 , A61Q19/02 , A61Q19/04
摘要： The use of microbially encapsulated materials (filled biocapsules), in particular yeast, in cosmetic end formulations is described.
摘要翻译：描述了在化妆品末端制剂中使用微生物包封的材料（填充的生物胶囊），特别是酵母。

5. 发明申请

WO2005094772A3 USE OF BENZOPHENONE UV FILTERS FOR PREVENTING TANNING 审中-公开
标题翻译：苯并噻唑紫外线过滤器用于防止TANNING的使用
公开(公告)号：WO2005094772A3
公开(公告)日：2005-12-01
申请号：PCT/EP2005051325
申请日：2005-03-23
申请人： CIBA SC HOLDING AG , BASCHONG WERNER
发明人： BASCHONG WERNER
IPC分类号： A61K8/44 , A61Q17/04 , A61K7/42
CPC分类号： A61K8/445 , A61Q17/04
摘要： The invention describes the use of organic UV filters of formula (I) wherein R, and R2, ' independently from each other are hydrogen, C1-C2,,alkyl, C2-C10alkenyl, C3 C,Ocycloalkyl, C3-C10cycloalkenyl, or R, and. R2 togethér with the nitrogen atom to which they are bonded can form a 5- or 6-membered ring; R3 and R4, independently from each other are C1-C20alkyl, C2 C,Oalkenyl, C3-C12cycloalkyl, C3-Ct0cycloalkenyl, C1-C12alkoxy, C,-C20alkoxycarbonyl, C1-C,zalkylamino, C1-C12dialkylamino, aryl, heteroaryl, optionally substituted, substituents which confer solubility in water, chosen from the group consisting of a nitrile group, carboxylate, sulfonate or ammonium radicals; X is hydrogen, COOR5, CONR6R7; R5, Rs and R7, independently from each other are hydrogen, C1-C20alkyl, C2-C10alkenyl, C3-C,0cycloalkyl, C3 C10cycloalkenyl, (Y-0),,-Z-aryl; Y is -(CH2)2 , (CH2)3, -(CH2)4-, -CH(CH3)-CH2 ; Z is -CH2 CH3i -CH2-CH,CH3, -CH2 CH2 CH2 CH3, -CH(CH3)-CH,; m is from 0 to 3; n. is from 0 to 4; o is from 1 to 20; for preventing tanning human skin, and their use in cosmetic and pharmaceutical formulations, as anti-wrinkling agents, skin-firming agents and as anti-skin lifting agents.
摘要翻译：本发明描述了使用式（I）的有机UV滤光器，其中R 1和R 2彼此独立地是氢，C 1 -C 2烷基，C 2 -C 10烯基，C 3 C，O环烷基，C 3 -C 10环烯基或R ，和。 R2与它们所键合的氮原子可以形成5-或6-元环; R 3和R 4彼此独立地是C 1 -C 20烷基，C 2 C，O烯基，C 3 -C 12环烷基，C 3 -C 10环烯基，C 1 -C 12烷氧基，C 1 -C 20烷氧基羰基，C 1 -C 8烷基氨基，C 1 -C 12二烷基氨基，芳基，取代基，其赋予在水中溶解度的取代基，其选自腈基，羧酸根，磺酸根或铵基; X是氢，COOR 5，CONR 6 R 7; R 5，R 5和R 7彼此独立地是氢，C 1 -C 20烷基，C 2 -C 10烯基，C 3 -C 6环烷基，C 3 -C 10环烯基，（Y-O） Y是 - （CH 2）2， - （CH 2）3， - （CH 2）4 - ， - CH（CH 3） Z为-CH2 CH3i -CH2-CH，CH3，-CH2 CH2 CH2 CH3，-CH（CH3）-CH， m为0〜3; ñ。为0〜4; o为1〜20; 用于防止鞣制人皮肤，以及它们在化妆品和药物制剂中的用途，作为抗皱剂，皮肤紧致剂和抗皮肤提起剂。

6. 发明专利

JP2001048764A USE OF PULVERIZED MIXTURE OF PIGMENTS FOR PREVENTION OF SUNBURN AND IMPARTING GLOSS TO SKIN AND HAIR 失效
公开(公告)号：JP2001048764A
公开(公告)日：2001-02-20
申请号：JP2000208214
申请日：2000-07-10
申请人： CIBA SC HOLDING AG
发明人： FANKHAUSER PETER , LUTHER HELMUT , BASCHONG WERNER
IPC分类号： A61K8/00 , A61K8/04 , A61K8/19 , A61K8/30 , A61K8/33 , A61K8/34 , A61K8/35 , A61K8/36 , A61K8/365 , A61K8/368 , A61K8/37 , A61K8/40 , A61K8/42 , A61K8/44 , A61K8/46 , A61K8/49 , A61K8/55 , A61K8/58 , A61K8/60 , A61K8/73 , A61K8/89 , A61K8/898 , A61K8/96 , A61Q1/00 , A61Q1/04 , A61Q5/00 , A61Q17/04 , A61Q19/02 , C07F7/10 , C09K3/00 , C09K15/06 , C09K15/30 , A61K7/42 , A61K7/00
摘要： PROBLEM TO BE SOLVED: To provide pulverized organic UV filter preventing skin from sunburn and simultaneously imparting gloss to skin. SOLUTION: The organic UV filter which prevents skin from sunburn and imparts gloss to skin and hair uses the pulverized organic pigments selected from triazines, benzotriazoles, amides having vinyl group, derivatives of cinnamic acid, suflonated benzimidazoles, derivatives of Fisher's base, diphenylmalonitriles, oxalylamides, derivatives of camphor, diphenylacrylates, p-aminobenzoic acid and their derivatives, salicilates and benzophenones.

7. 发明专利

BRPI0518569A2 未知
公开(公告)号：BRPI0518569A2
公开(公告)日：2008-11-25
申请号：BRPI0518569
申请日：2005-10-24
申请人： CIBA SC HOLDING AG
发明人： BASCHONG WERNER , REICH OLIVER , MONGIAT SEBASTIEN
IPC分类号： A61K31/05 , A61K31/222 , A61K31/255 , A61K31/34 , A61K31/445 , A61P17/00 , A61P17/16 , A61P27/14 , A61P29/00 , A61P43/00

8. 发明专利

GB2412866A Amino-benzophenone UV filter formulations for the prevention of tanning 未知
公开(公告)号：GB2412866A
公开(公告)日：2005-10-12
申请号：GB0505720
申请日：2005-03-21
申请人： CIBA SC HOLDING AG
发明人： BASCHONG WERNER
IPC分类号： A61K8/44 , A61Q17/04 , A61K7/44
摘要： Ultraviolet filter compounds of formula 1: wherein R1 and R2 are hydrogen, C1-20alkyl, C2-20alkenyl, C3-10cycloalkyl, C3-10cycloalkenyl, R1 and R2 together with the nitrogen to which they are attached form a 5- or 6-membered ring; R3 and R4 are C1-20alkyl, C2-20alkenyl, C3-10cycloalkyl, C3-10cycloalkenyl, C1-12alkoxy, C1-20alkoxycarbonyl, C1-12alkylamino, C1-12 dialkylamino, aryl, heteroaryl, all optionally substituted with substituents which confer solubility in water, chosen from nitrile, carboxylate, sulfonate or ammonium radicals; X is hydrogen, C(O)OR5 or C(O)NR6R7; R5, R6 and R7 are hydrogen, C1-20alkyl, C2-20alkenyl, C3-10cycloalkyl, C3-10cycloalkenyl, (Y-O)o-Z-aryl; Y is -(CH2)2-, -(CH2)3-, -(CH2)4-, -CH(CH3)-CH2-; Z is -CH2-CH3, -CH2-CH2-CH3, -CH2-CH2-CH2-CH3, -CH(CH3)-CH3; m is 0-3, n is 0-4, o is 1-20; for the prevention of the tanning of human skin, and their use in cosmetic and pharmaceutical formulations. A preferred compound features X as C(O)OR5 and R5 as C6H13. Formulations may also comprise for example antioxidants, pigment regulating agents, skin lightening agents, such as kojic acid, arbutin, quercitin, aloesin, azelain acid, guaiol and ellagic acid, anti-wrinkling agents, skin firming agents and anti-skin lifting agents.

9. 发明专利

DE69806638T2 未知
公开(公告)号：DE69806638T2
公开(公告)日：2003-03-13
申请号：DE69806638
申请日：1998-12-09
申请人： CIBA SC HOLDING AG
发明人： BASCHONG WERNER , HUEGLIN DIETMAR , FANKHAUSER PETER , HEINEMANN GERD
IPC分类号： C12N9/99 , A61K8/00 , A61K8/34 , A61K8/73 , A61Q11/00 , C08B37/08 , A61K7/16
摘要： A description is given of the use of polyanionic and polyanionically-derivatised natural polysaccharides or non-derivatised natural polysaccharides for inhibiting alkaline phosphatase and of oral compositions for preventing bacterial plaque, which comprises (a) 0 to 10% by weight of at least one linear molecularly dehydrated polyphosphate salt, and (b) 0.0001 to 5% by weight of a polyanionic or polyanionically-derivatised natural polysaccharide.

10. 发明专利

AU2372201A Use of microbially encapsulated materials in cosmetic end formulations 未知
公开(公告)号：AU2372201A
公开(公告)日：2001-07-24
申请号：AU2372201
申请日：2001-01-04
申请人： CIBA SC HOLDING AG
发明人： BASCHONG WERNER , HUGLIN DIETMAR
IPC分类号： C12N1/16 , A61K8/00 , A61K8/04 , A61K8/06 , A61K8/11 , A61K8/33 , A61K8/34 , A61K8/67 , A61K8/69 , A61K8/92 , A61K8/96 , A61K8/97 , A61K8/98 , A61K8/99 , A61Q1/02 , A61Q3/00 , A61Q3/02 , A61Q5/00 , A61Q5/02 , A61Q9/02 , A61Q11/00 , A61Q13/00 , A61Q15/00 , A61Q17/02 , A61Q17/04 , A61Q19/00 , A61Q19/10 , A61K7/00
摘要： The use of microbially encapsulated materials (filled biocapsules), in particular yeast, in cosmetic end formulations is described.

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