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1. 发明授权

US3852424A Purified ferrimycin and process for obtaining same 失效
标题翻译：纯化的菲律宾蛋白及其制备方法
公开(公告)号：US3852424A
公开(公告)日：1974-12-03
申请号：US62665066
申请日：1966-10-19
申请人： CIBA GEIGY CORP
发明人： GAEUMANN E , GAEUMAN T , BICKEL H , PRELOG V , VISCHER E
IPC分类号： A61K31/445 , A61K21/00
CPC分类号： A61K31/445 , Y10S435/886
摘要： The antibiotic ferrimycin A, its components ferrimycin A1 and ferrimycin A2 and the corresponding iron-free compounds desferrimycin A, desferrimycin A1 and desferrimycin A2, and also pharmaceutical preparations which contain these products, and a process for the manufacture of these substances and mixtures containing them. The antibiotic ferrimycin belongs to the sideramycins, a class of iron-containing or iron-binding antibiotics, to which also the antibiotics grisein, albomycin and A 1787 belong. The sideramycins are characterized by their antibiotic effect being antagonized by the ferrioxamines; see Bickel et al., Experientia 16 (1960) 129.
摘要翻译：抗生素亚铁蛋白A，其组分亚铁霉素A1和亚铁蛋白A2以及相应的无铁化合物脱铁霉素A，脱铁霉素A1和脱铁霉素A2，以及含有这些产物的药物制剂，以及制备这些物质和混合物的方法。抗生素亚铁霉素属于西格他霉素，一类含铁或铁结合抗生素，抗生素吉非敏，阿霉素和A1787也属于此类抗生素。仙茅素的特征在于其抗生素作用被铁三胺拮抗; 见Bickel等人，Experientia 16（1960）129。

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