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1. 发明专利

JPH10236977A ORTHODONTIC MEDICINE CONTAINING PTH 失效
公开(公告)号：JPH10236977A
公开(公告)日：1998-09-08
申请号：JP36089297
申请日：1997-12-26
申请人： CHUGAI PHARMACEUTICAL CO LTD
发明人： SOMA SHUNICHI , IWAMOTO YOUTAI , KURISU KOJIRO , HIGUCHI YOSHINOBU
IPC分类号： A61K38/22 , A61P1/02 , A61P43/00
摘要： PROBLEM TO BE SOLVED: To prepare an effective orthodontic medicine containing a PTH (parathyroid hormone), capable of enhancing the movement of tooth in orthodontics and actually utilized in clinic by using the PTH or a derivative thereof as an active ingredient. SOLUTION: This orthodontic medicine containing a PTH contains one or more kinds of the PTHs or a derivative thereof as an active ingredient. The PTH or the derivative thereof is preferably the recombinant human PTH produced by a gene engineering method and comprising 34 amino acid residues. The dosage form of the objective medicine is, for example, an injection, a microcapsule, a mouth mucosal preparation, etc., and preferably the noninvasive one. The administration method is preferably a topical administration when a specific tooth is intended to move. The topical administration is preferably carried out by allowing the objective medicine to be successively absorbed from the surface of the mucosa or successively infusing the objective medicine to the limited part by using a sustained release basis. When the whole teeth are moved, the whole body administration is convenient and preferable. The dose amount in the case of the whole body administration is preferably 10μg to 1mg.

2. 发明专利

AU740610B2 Orthodontic remedy containing PTH 未知
公开(公告)号：AU740610B2
公开(公告)日：2001-11-08
申请号：AU7888698
申请日：1997-12-26
申请人： CHUGAI PHARMACEUTICAL CO LTD
发明人： SOMA SHUNICHI , IWAMOTO MASAHIRO , KURISU KOJIRO , HIGUCHI YOSHINOBU
IPC分类号： A61K38/29 , A61K38/24
摘要： Orthodontic remedies containing parathyroid hormone (PTH) or one or more PTH derivatives as the active ingredient(s).

3. 发明专利

AU7888698A Orthodontic remedy containing PTH 未知
公开(公告)号：AU7888698A
公开(公告)日：1998-07-31
申请号：AU7888698
申请日：1997-12-26
申请人： CHUGAI PHARMACEUTICAL CO LTD
发明人： SHUNICHI SOMA , HIGUCHI YOSHINOBU , KURISU KOJIRO , IWAMOTO MASAHIRO
IPC分类号： A61K38/29 , A61K38/24
摘要： Orthodontic remedies containing parathyroid hormone (PTH) or one or more PTH derivatives as the active ingredient(s).

4. 发明专利

CA2276177A1 ORTHODONTIC REMEDY CONTAINING PTH 未知
公开(公告)号：CA2276177A1
公开(公告)日：1998-07-09
申请号：CA2276177
申请日：1997-12-26
申请人： CHUGAI PHARMACEUTICAL CO LTD
发明人： IWAMOTO MASAHIRO , SOMA SHUNICHI , HIGUCHI YOSHINOBU , KURISU KOJIRO
IPC分类号： A61K38/29 , A61K38/24
摘要： An orthodontic remedy containing a parathyroid hormone (PTH) or at least one PTH derivative as the active ingredient.

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