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2. 发明申请

US20110272836A1 ECCENTRIC VESSELS 审中-公开
公开(公告)号：US20110272836A1
公开(公告)日：2011-11-10
申请号：US13084627
申请日：2011-04-12
申请人： MARK J. KEEGAN , Donna L. Kessel
发明人： MARK J. KEEGAN , Donna L. Kessel
IPC分类号： B29B9/12 , B01F15/06 , B01F3/08 , B01F7/00
CPC分类号： B01F3/0807 , B01F7/18 , B01F15/00876
摘要： Vessels, including non-symmetric vessels for mixing fluids, are disclosed. In one aspect, the vessel is one that has a non-rotationally-symmetric interior surface. For example, the vessel may have an oblique frustoconical shape. At least a portion of the mixing vessel may have horizontal cross-sections having varying area, in some embodiments. The vessel may be formed from any suitable material, e.g., glass, plastic, or stainless steel. Such vessels may be used, according to certain embodiments, to create single, double or other multiple emulsions, for example, by exposing liquids or fluids contained therein to relatively high shear rates. In some cases, the vessel may be designed to be pharmaceutical-grade and/or meet ASME Bioprocessing Equipment (ASME-BPE) standards. For instance, the vessel may be used under conditions where the vessel is sterile, and/or the vessel may have a polished internal surface. In some cases, the vessel includes a temperature control system surrounding at least a portion of the vessel. Other aspects relate to methods of using such vessels, methods of creating or preparing such vessels, or kits involving such vessels.
摘要翻译：公开了包括用于混合流体的非对称容器的容器。在一个方面，容器是具有非旋转对称内表面的容器。例如，容器可以具有倾斜的截头圆锥形状。在一些实施例中，混合容器的至少一部分可具有不同面积的水平横截面。容器可以由任何合适的材料形成，例如玻璃，塑料或不锈钢。根据某些实施方案，可以使用这样的容器来产生单一，双重或其它多重乳液，例如通过将其中包含的液体或液体暴露于相对高的剪切速率。在某些情况下，容器可以设计成药物级和/或符合ASME生物处理设备（ASME-BPE）标准。例如，容器可以在容器无菌的条件下使用，和/或容器可以具有抛光的内表面。在一些情况下，容器包括围绕容器的至少一部分的温度控制系统。其他方面涉及使用这种血管的方法，制造或制备这种血管的方法，或涉及这种血管的试剂盒。

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