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1. 发明授权

EP0197856B1 Composition pour bains à base de psoralène dans le traitement du psoriasis 失效转让
标题翻译：基于PSORALENE治疗PSORIASIS的组合物
公开(公告)号：EP0197856B1
公开(公告)日：1990-10-03
申请号：EP86400693.7
申请日：1986-03-28
申请人： CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA - CIRD GALDERMA Groupement d'Intérêt Economique dit:
发明人： Shroot, Braham Villa 35 - Hameaux de Val Bosquet , Allec, Josiane LES VERGERS DE VAL CONSTANCE
IPC分类号： A61K31/35 , A61K7/42
CPC分类号： A61K31/35 , A61K8/498 , A61Q17/04 , Y10S514/863
摘要： 1. Composition for baths, in the treatment of psoriasis and skin conditions, presented in the form of an oily product, characterized in that the said composition is essentially made up of 10 to 79.9% by weight of a hydrophilic phase consisting of at least one polyoxyethylenated and/or polyoxypropylenated fatty alcohol, one fatty ester of polyoxyethylenated or polyoxypropylenated glycerol, one polyoxyethylenated or polyoxypropylenated sorbitol or sorbitan ester, one polyoxyethylenated and/or polyoxypropylenated fatty ester or one polyoxyethylenated alkylphenol, the content of ethylene oxide and/or propylene oxide being between 2 and 40 moles, and 20 to 89.9% by weight of a lipophilic phase consisting of at least one ester of a fatty acid and/or alcohol, one saturated or unsaturated fatty alcohol, one saturated or unsaturated fatty acid, one hydrocarbon or one fatty acid mono-, di- or triglyceride, and contains from 0.1 to 2% by weight of an active principle belonging to the psoralen class, the said composition after dilution in water giving rise to a bath of milky appearance.
摘要翻译： 1.用于治疗牛皮癣和皮肤状况的浴液的组合物，以油性产品的形式提供，其特征在于所述组合物基本上由10至79.9重量％的由至少一个聚氧乙烯化和/或聚氧丙烯化脂肪醇，聚氧乙烯化或聚氧丙烯化甘油的一种脂肪酯，一种聚氧乙烯化或聚氧丙烯化山梨糖醇或脱水山梨糖醇酯，一种聚氧乙烯化和/或聚氧丙烯化脂肪酯或一种聚氧乙烯化烷基酚，环氧乙烷和/ 2至40摩尔，和20至89.9重量％的由至少一种脂肪酸和/或醇酯，一种饱和或不饱和脂肪醇，一种饱和或不饱和脂肪酸，一种烃或一种烃组成的亲油相脂肪酸单 - ，二 - 或甘油三酸酯，并且含有0.1至2重量％的属于补骨脂素的活性成分 ss，所述组合物在水中稀释后产生乳白色外观。

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