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1. 发明申请

WO2007038591A1 APPARATUS AND METHODS FOR TREATING URETHRAL INCONTINENCE 审中-公开
标题翻译：治疗尿失禁的手段和方法
公开(公告)号：WO2007038591A1
公开(公告)日：2007-04-05
申请号：PCT/US2006/037666
申请日：2006-09-28
申请人： CELLULAR BIOENGINEERING, INC. , LEE, Anthony , WUH, Hank
发明人： LEE, Anthony , WUH, Hank
IPC分类号： A61M25/10 , A61M29/00 , A61B17/12
CPC分类号： A61M25/0084 , A61B2017/00805 , A61B2017/00827 , A61M25/0017 , A61M25/04 , A61M2025/0096
摘要： The invention relates to apparatus (A) for injection of therapeutic agents into surrounding lumenal tissue, for example, to treat urinary incontinence and gastroesophageal reflux disease.
摘要翻译：本发明涉及用于将治疗剂注射到周围管腔组织中的装置（A），例如治疗尿失禁和胃食管反流病。

2. 发明申请

WO2007047425A1 RESORBABLE CORNEA BUTTON 审中-公开
标题翻译：可折叠的CORNEA按钮
公开(公告)号：WO2007047425A1
公开(公告)日：2007-04-26
申请号：PCT/US2006/040053
申请日：2006-10-12
申请人： CELLULAR BIOENGINEERING, INC. , LUI, Ge Ming , LEE, Anthony , DONG, Shaosheng , WUH, Hank
发明人： LUI, Ge Ming , LEE, Anthony , DONG, Shaosheng , WUH, Hank
IPC分类号： C12N5/08 , A61K35/44 , A61L27/38 , A61P27/02
CPC分类号： C12N5/0621 , A61F2/142 , A61K35/12 , A61L27/3604 , A61L27/3641 , A61L27/3808 , A61L27/3839 , A61L27/58 , A61L2430/16 , C12N5/0068 , C12N2533/54 , C12N2533/80 , C12N2533/92
摘要： The present invention provides a resorbable corneal button comprised of a biodegradable polymer which is capable of supporting the growth and expansion of endothelial cells on it surface for use in transplantation healthy corneal endothelial cells to cornea tissue in need of a transplant and a method of using same.
摘要翻译：本发明提供了一种由可生物降解的聚合物组成的可再吸收的角膜按钮，其能够支持其表面上的内皮细胞的生长和扩张，用于将需要移植的角膜组织的健康角膜内皮细胞移植到其中并用于其中的方法。

3. 发明申请

WO2007100861A1 POLYMER COMPOSITION AND METHOD FOR REMOVING CONTAMINATES FROM A SUBSTRATE 审中-公开
标题翻译：聚合物组合物和从基底去除污染物的方法
公开(公告)号：WO2007100861A1
公开(公告)日：2007-09-07
申请号：PCT/US2007/005181
申请日：2007-02-28
申请人： CELLULAR BIOENGINEERING, INC. , EDGINGTON, Garry , DONG, Shaosheng , LUI, Ge Ming , WUH, Hank , SHERMAN, Stephen, L.
发明人： EDGINGTON, Garry , DONG, Shaosheng , LUI, Ge Ming , WUH, Hank , SHERMAN, Stephen, L.
IPC分类号： B08B7/00 , B23B7/06 , C11D17/04
CPC分类号： C11D17/041 , C11D3/222 , C11D3/223 , C11D3/225 , C11D3/226 , C11D3/227 , C11D3/228 , C11D3/3753 , C11D3/3765 , C11D3/3773 , C11D3/3776 , C11D11/0005 , C11D11/0023 , Y10T428/31855
摘要： This invention relates to an aqueous polymer composition and to films formed from this aqueous composition. The aqueous composition may be used in a method for removing contaminate material from a substrate. The aqueous polymer composition may comprise: water; and at least one water-soluble film forming polymer. In one embodiment, the aqueous composition may further comprise at least one chelating agent and/or at least one surfactant. The aqueous polymer composition may be applied to a contaminated substrate or to a clean substrate which is subjected to subsequent contamination. The aqueous composition may be dehydrated and/or the polymer may be crosslinked to form a film. When applied to a contaminated substrate, the film may combine with the contaminates. When applied to a clean substrate, the contaminate material may subsequently contact and adhere to the film. The film combined with the contaminate material may be separated from the substrate, with the result being removal of the contaminate material from the substrate.
摘要翻译：本发明涉及一种水性聚合物组合物和由该水性组合物形成的薄膜。水性组合物可以用于从基材中除去污染物质的方法。水性聚合物组合物可以包含：水; 和至少一种水溶性成膜聚合物。在一个实施方案中，水性组合物还可包含至少一种螯合剂和/或至少一种表面活性剂。水性聚合物组合物可以施加到受污染的基底或经受后续污染的清洁基底。水性组合物可以脱水和/或聚合物可以交联以形成膜。当应用于污染的基材时，该膜可能与污染物结合。当施加到干净的基底上时，污染物质可以随后接触并粘附到膜上。与污染物质结合的膜可以与基底分离，结果是从基底去除污染物质。

4. 发明申请

WO2007041308A1 APPARATUS AND METHOD FOR DETECTING ACTIVITY OF LIVING CELLS 审中-公开
标题翻译：用于检测活细胞活性的装置和方法
公开(公告)号：WO2007041308A1
公开(公告)日：2007-04-12
申请号：PCT/US2006/038093
申请日：2006-09-29
申请人： CELLULAR BIOENGINEERING, INC. , CHINN, Kevin Shew , JIM, Kevin T. C. , YEN, Brian , WUH, Hank
发明人： CHINN, Kevin Shew , JIM, Kevin T. C. , YEN, Brian , WUH, Hank
IPC分类号： G01N21/64
CPC分类号： G01N21/6428 , G01N21/6454 , G01N21/6456
摘要： An apparatus for detecting the activity of living cells comprises a cell growth medium layer (104) for receiving the cells (100) and an imaging sensor (101) , e.g. a CCD array, wherein the cell growth medium layer and the imaging sensor are separated from each other only by an inert protective layer (102) and an optional diamond-like carbon layer (111) . The cells may be stained by a fluorescent dye, such as a calcium, ion, voltage or pH indicator dye. Upon illumination by a light source (130) the cells emit fluorescent light which is directly detected by the imaging senor without any optical transfer elements such as lenses or mirrors. The apparatus ,may be enclosed in a housing (103) provided with gas and liquid ports (107, 108, 109) . Furthermore the apparatus may comprise means (120) for applying a stimulation signal to the cells.
摘要翻译：用于检测活细胞活性的装置包括用于接收细胞（100）的细胞生长培养基层（104）和成像传感器（101）。 CCD阵列，其中细胞生长培养基层和成像传感器仅通过惰性保护层（102）和任选的类金刚石碳层（111）彼此分离。细胞可能被荧光染料染色，如钙，离子，电压或pH指示剂染料。当通过光源（130）照射时，电池发射由成像传感器直接检测的荧光，而没有任何光学转移元件，例如透镜或反射镜。该装置可以封闭在设置有气体和液体端口（107,108,109）的壳体（103）中。此外，装置可以包括用于向细胞施加刺激信号的装置（120）。

5. 发明公开

EP1941262A1 APPARATUS AND METHOD FOR DETECTING ACTIVITY OF LIVING CELLS 审中-公开
标题翻译：装置和方法检测活细胞的活性
公开(公告)号：EP1941262A1
公开(公告)日：2008-07-09
申请号：EP06825259.2
申请日：2006-09-29
申请人： Cellular Bioengineering, Inc.
发明人： CHINN, Kevin Shew , JIM, Kevin T. C. , YEN, Brian , WUH, Hank
IPC分类号： G01N21/64
CPC分类号： G01N21/6428 , G01N21/6454 , G01N21/6456
摘要： An apparatus for detecting the activity of living cells comprises a cell growth medium layer (104) for receiving the cells (100) and an imaging sensor (101) , e.g. a CCD array, wherein the cell growth medium layer and the imaging sensor are separated from each other only by an inert protective layer (102) and an optional diamond-like carbon layer (111) . The cells may be stained by a fluorescent dye, such as a calcium, ion, voltage or pH indicator dye. Upon illumination by a light source (130) the cells emit fluorescent light which is directly detected by the imaging senor without any optical transfer elements such as lenses or mirrors. The apparatus ,may be enclosed in a housing (103) provided with gas and liquid ports (107, 108, 109) . Furthermore the apparatus may comprise means (120) for applying a stimulation signal to the cells.

6. 发明公开

EP1945759A1 RESORBABLE CORNEA BUTTON 审中-公开
标题翻译：可吸收的角膜扣
公开(公告)号：EP1945759A1
公开(公告)日：2008-07-23
申请号：EP06825895.3
申请日：2006-10-12
申请人： Cellular Bioengineering, Inc.
发明人： LUI, Ge Ming , LEE, Anthony , DONG, Shaosheng , WUH, Hank
IPC分类号： C12N5/08 , A61K35/44 , A61L27/38 , A61P27/02
CPC分类号： C12N5/0621 , A61F2/142 , A61K35/12 , A61L27/3604 , A61L27/3641 , A61L27/3808 , A61L27/3839 , A61L27/58 , A61L2430/16 , C12N5/0068 , C12N2533/54 , C12N2533/80 , C12N2533/92
摘要： The present invention provides a resorbable corneal button comprised of a biodegradable polymer which is capable of supporting the growth and expansion of endothelial cells on it surface for use in transplantation healthy corneal endothelial cells to cornea tissue in need of a transplant and a method of using same.

7. 发明授权

EP1998907B1 POLYMER COMPOSITION AND METHOD FOR REMOVING CONTAMINATES FROM A SUBSTRATE 有权
标题翻译：聚合物组合物和方法去除污染物从衬底
公开(公告)号：EP1998907B1
公开(公告)日：2011-02-16
申请号：EP07751912.2
申请日：2007-02-28
申请人： Cellular Bioengineering, Inc.
发明人： EDGINGTON, Garry , DONG, Shaosheng , LUI, Ge Ming , WUH, Hank , SHERMAN, Stephen, L.
IPC分类号： B08B7/00 , B23B7/06 , C11D17/04
CPC分类号： C11D17/041 , C11D3/222 , C11D3/223 , C11D3/225 , C11D3/226 , C11D3/227 , C11D3/228 , C11D3/3753 , C11D3/3765 , C11D3/3773 , C11D3/3776 , C11D11/0005 , C11D11/0023 , Y10T428/31855
摘要： This invention relates to an aqueous polymer composition and to films formed from this aqueous composition. The aqueous composition may be used in a method for removing contaminate material from a substrate. The aqueous polymer composition may comprise: water; and at least one water-soluble film forming polymer. In one embodiment, the aqueous composition may further comprise at least one chelating agent and/or at least one surfactant. The aqueous polymer composition may be applied to a contaminated substrate or to a clean substrate which is subjected to subsequent contamination. The aqueous composition may be dehydrated and/or the polymer may be crosslinked to form a film. When applied to a contaminated substrate, the film may combine with the contaminates. When applied to a clean substrate, the contaminate material may subsequently contact and adhere to the film. The film combined with the contaminate material may be separated from the substrate, with the result being removal of the contaminate material from the substrate.

8. 发明公开

EP1998907A1 POLYMER COMPOSITION AND METHOD FOR REMOVING CONTAMINATES FROM A SUBSTRATE 有权
标题翻译：聚合物组合物和方法去除污染物从衬底
公开(公告)号：EP1998907A1
公开(公告)日：2008-12-10
申请号：EP07751912.2
申请日：2007-02-28
申请人： Cellular Bioengineering, Inc.
发明人： EDGINGTON, Garry , DONG, Shaosheng , LUI, Ge Ming , WUH, Hank , SHERMAN, Stephen, L.
IPC分类号： B08B7/00 , B23B7/06 , C11D17/04
CPC分类号： C11D17/041 , C11D3/222 , C11D3/223 , C11D3/225 , C11D3/226 , C11D3/227 , C11D3/228 , C11D3/3753 , C11D3/3765 , C11D3/3773 , C11D3/3776 , C11D11/0005 , C11D11/0023 , Y10T428/31855
摘要： This invention relates to an aqueous polymer composition and to films formed from this aqueous composition. The aqueous composition may be used in a method for removing contaminate material from a substrate. The aqueous polymer composition may comprise: water; and at least one water-soluble film forming polymer. In one embodiment, the aqueous composition may further comprise at least one chelating agent and/or at least one surfactant. The aqueous polymer composition may be applied to a contaminated substrate or to a clean substrate which is subjected to subsequent contamination. The aqueous composition may be dehydrated and/or the polymer may be crosslinked to form a film. When applied to a contaminated substrate, the film may combine with the contaminates. When applied to a clean substrate, the contaminate material may subsequently contact and adhere to the film. The film combined with the contaminate material may be separated from the substrate, with the result being removal of the contaminate material from the substrate.

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