专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明专利

HRP20180107T1 ACETILIRANI SALICILATI MASNIH KISELINA I NJIHOVA UPOTREBA 未知
公开(公告)号：HRP20180107T1
公开(公告)日：2018-03-09
申请号：HRP20180107
申请日：2018-01-22
申请人： CATABASIS PHARMACEUTICALS INC
发明人： MILNE JILL C , JIROUSEK MICHAEL R , BEMIS JEAN E , SMITH JESSE J
IPC分类号： C07C233/18 , A61K31/165 , A61K31/17 , A61K31/232 , A61K31/235 , C07C69/587 , C07C69/90 , C07C69/94 , C07C233/49 , C07C233/55 , C07C235/60 , C07C237/22 , C07C271/28 , C07C275/42 , C07D295/192

2. 发明专利

MX337605B DERIVADOS DE FUMARATO DE ACIDO GRASO Y SUS USOS. 未知
公开(公告)号：MX337605B
公开(公告)日：2016-03-10
申请号：MX2012007981
申请日：2011-01-07
申请人： CATABASIS PHARMACEUTICALS INC
发明人： JIROUSEK MICHAEL R , MILNE JILL C , SMITH JESSE J , BEMIS JEAN E , VU CHI B
IPC分类号： C07D207/40 , A01N37/00 , A01N37/18 , A61K31/40 , A61K31/4965 , C07C233/38 , C07C233/49 , C07D295/18
摘要： La invención se refiere a derivados de fumarato de ácido graso, a composiciones que comprenden una cantidad efectiva de un derivado de fumarato de ácido graso y a métodos para tratar o prevenir cáncer, un trastorno metabólico o trastorno neurodegenerativo que comprende la administración de una cantidad efectiva 'de un derivado de fumarato de ácido graso.

3. 发明专利

NZ601698A Fatty acid fumarate derivatives and their uses 未知
公开(公告)号：NZ601698A
公开(公告)日：2015-04-24
申请号：NZ60169811
申请日：2011-01-07
申请人： CATABASIS PHARMACEUTICALS INC
发明人： MILNE JILL C , SMITH JESSE J , VU CHI B , BEMIS JEAN E , JIROUSEK MICHAEL R
IPC分类号： A01N37/00 , A01N37/18 , A61K31/16 , A61K31/22 , C07C233/20 , C07C233/38 , C07C233/49
摘要： Disclosed are fatty acid fumarate derivatives as represented by the general formulae (I) or (II), or a pharmaceutically acceptable salt, hydrate, solvate, enantiomer, or stereoisomer thereof; wherein each W1,W2, W1′ and W2′ is independently null, O, S, NH, or NR, or W1 and W2, or W1′ and W2′ can be taken together to form an optionally substituted imidazolidine or piperazine group; each n, o, p, q, n′, o′, p′, and q′ is independently 0, 1, or 2; each m and m′ is independently 0, 1, 2, or 3; each Z and Z′ is independently -H, or a fatty acid moiety, or a 1,2-dithiolane substituted alkyl derivative all as defined herein; provided that at least one of Z and Z′ is not H; and wherein the remaining substituents are as defined herein. Representative compounds include (E)-methyl 4-(2-(4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenamidoethylamino)-4-oxobut-2-enoate, (E)-methyl 4-(2-(5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenamidoethylamino)-4-oxobut-2-enoate, (S)-6-((4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenamido)-2-((E)-4-methoxy-4-oxobut-2-enamido)hexanoic acid, (S)-1,3-dihydroxypropan-2-yl 6-((4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenamido)-2-((E)-4-methoxy-4-oxobut-2-enamido)hexanoate, (S)-5-((4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenamido)-2-((E)-4-methoxy-4-oxobut-2-enamido)pentanoic acid, (S)-1,3-dihydroxypropan-2-yl 5-((4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenamido)-2-((E)-4-methoxy-4-oxobut-2-enamido)pentanoate, and (S)-1,3-dihydroxypropan-2-yl 2-((4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenamido)-5-((E)-4-ethoxy-4-oxobut-2-enamido)pentanoate. Also disclosed is a pharmaceutical composition comprising a compound as defined above, and a pharmaceutically acceptable carrier, for use in the treatment of a neurodegenerative disease, an inflammation, or an inflammatory disease.

4. 发明专利

CO6571913A2 Derivados de fumarato de ácido graso y sus usos 未知
公开(公告)号：CO6571913A2
公开(公告)日：2012-11-30
申请号：CO12133089
申请日：2012-08-08
申请人： CATABASIS PHARMACEUTICALS INC
发明人： VU CHI B , BEMIS JEAN , JIROUSEK MICHAEL R , MILNE JILL C , SMITH JESSE J
IPC分类号： A01N37/00
摘要： La invención se refiere a derivados de fumarato de ácido graso, a composiciones que comprenden una cantidad efectiva de un derivado de fumarato de ácido graso, y a métodos para tratar o prevenir cáncer y trastornos metabólicos, autoinmunes o neurodegenerativos, que comprende la administración de una cantidad efectiva de un derivado de fumarato de ácido graso. Todas las patentes, solicitudes de patente y publicaciones mencionadas en la presente se incorporan en la presente por referencia en su totalidad.

5. 发明专利

AU2009268610B2 Fatty Acid Acetylated Salicylates and their uses 未知
公开(公告)号：AU2009268610B2
公开(公告)日：2012-10-04
申请号：AU2009268610
申请日：2009-07-08
申请人： CATABASIS PHARMACEUTICALS INC
发明人： BEMIS JEAN E , MILNE JILL C , JIROUSEK MICHAEL R , SMITH JESSE J
IPC分类号： C07C233/18 , A61K31/165 , A61K31/17 , A61K31/232 , A61K31/235 , C07C69/587 , C07C69/90 , C07C69/94 , C07C233/49 , C07C233/55 , C07C235/60 , C07C237/22 , C07C271/28 , C07C275/42 , C07D295/192
摘要： The invention relates to Fatty Acid Acetylated Salicylate Derivatives; compositions comprising an effective amount of a Fatty Acid Acetylated Salicylate Derivative; and methods for treating or preventing an inflammatory disorder comprising the administration of an effective amount of a Fatty Acid Acetylated Salicylate Derivative.

6. 发明专利

MX2011000273A SALICILATOS ACETILADOS CON ACIDOS GRASOS Y SUS USOS. 未知
公开(公告)号：MX2011000273A
公开(公告)日：2011-05-23
申请号：MX2011000273
申请日：2009-07-08
申请人： CATABASIS PHARMACEUTICALS INC
发明人： JIROUSEK MICHAEL R , BEMIS JEAN E , MILNE JILL C , SMITH JESSE J
IPC分类号： C07C233/18 , A61K31/165 , A61K31/17 , A61K31/232 , A61K31/235 , C07C69/587 , C07C69/90 , C07C69/94 , C07C233/49 , C07C233/55 , C07C235/60 , C07C237/22 , C07C271/28 , C07C275/42 , C07D295/192
摘要： La invención se relaciona con Derivados de Salicilatos Acetilados con Ácidos Grasos; con composiciones que comprenden una cantidad efectiva de un Derivado de Salicilato Acetilado con Ácidos Grasos; y con métodos para tratar o prevenir un trastorno inflamatorio que comprende la administración de una cantidad efectiva de un Derivado de Salicilato Acetilado con Ácidos Grasos.

7. 发明专利

AU2009268610A1 Fatty Acid Acetylated Salicylates and their uses 未知
公开(公告)号：AU2009268610A1
公开(公告)日：2010-01-14
申请号：AU2009268610
申请日：2009-07-08
申请人： CATABASIS PHARMACEUTICALS INC
发明人： BEMIS JEAN E , JIROUSEK MICHAEL R , MILNE JILL C , SMITH JESSE J
IPC分类号： C07C233/18 , A61K31/165 , A61K31/17 , A61K31/232 , A61K31/235 , C07C69/587 , C07C69/90 , C07C69/94 , C07C233/49 , C07C233/55 , C07C235/60 , C07C237/22 , C07C271/28 , C07C275/42 , C07D295/192
摘要： The invention relates to Fatty Acid Acetylated Salicylate Derivatives; compositions comprising an effective amount of a Fatty Acid Acetylated Salicylate Derivative; and methods for treating or preventing an inflammatory disorder comprising the administration of an effective amount of a Fatty Acid Acetylated Salicylate Derivative.

8. 发明专利

CA2729186C FATTY ACID ACETYLATED SALICYLATES AND THEIR USES 未知
公开(公告)号：CA2729186C
公开(公告)日：2018-01-16
申请号：CA2729186
申请日：2009-07-08
申请人： CATABASIS PHARMACEUTICALS INC
发明人： MILNE JILL C , JIROUSEK MICHAEL R , BEMIS JEAN E , SMITH JESSE J
IPC分类号： C07C233/18 , A61K31/165 , A61K31/17 , A61K31/232 , A61K31/235 , C07C69/587 , C07C69/90 , C07C69/94 , C07C233/49 , C07C233/55 , C07C235/60 , C07C237/22 , C07C271/28 , C07C275/42 , C07D295/192
摘要： The invention relates to Fatty Acid Acetylated Salicylate Derivatives having a structure of Formula I: or pharmaceutically acceptable salts, hydrates, solvates, prodrugs, enantiomers, and stereoisomers thereof, wherein R1, R2, R3, R4, W1,W2,-----, a, b, c, d, n, o, p, q, t, Z and Q are as defined herein. This invention also relates to Fatty Acid Acetylated Salicylate Derivatives having a structure of Formula III: or pharmaceutically acceptable salts, hydrates, solvates, prodrugs, enantiomers, and stereoisomers thereof, wherein W1, W2,-----, a, b, c, d, n, o, p, q, t, u, Z, Q and R are as defined herein. Compositions comprising an effective amount of such compounds, and methods for treating or preventing an inflammatory disorder comprising the administration of an effective amount of such compounds are also provided.

9. 发明专利

DK2521447T3 FEDTSYREFUMARATER OG DERES ANVENDELSER 未知
公开(公告)号：DK2521447T3
公开(公告)日：2017-09-18
申请号：DK11732212
申请日：2011-01-07
申请人： CATABASIS PHARMACEUTICALS INC
发明人： VU CHI B , BEMIS JEAN E , JIROUSEK MICHAEL R , MILNE JILL C , SMITH JESSE J
IPC分类号： C07D207/40 , A61K31/197 , A61K31/221 , A61K31/385 , A61K31/40 , A61K31/495 , A61P25/28 , A61P29/00 , A61P35/00 , C07C233/20 , C07C233/38 , C07C233/49 , C07C323/41 , C07D241/04 , C07D295/18 , C07D339/04

10. 发明专利

AU2011204277B2 Fatty Acid Fumarate Derivatives and their uses 未知
公开(公告)号：AU2011204277B2
公开(公告)日：2015-12-24
申请号：AU2011204277
申请日：2011-01-07
申请人： CATABASIS PHARMACEUTICALS INC
发明人： VU CHI B , BEMIS JEAN E , JIROUSEK MICHAEL R , MILNE JILL C , SMITH JESSE J
IPC分类号： A01N37/00 , A01N37/18
摘要： The invention relates to Fatty Acid Fumarate Derivatives; compositions comprising an effective amount of a Fatty Acid Fumarate Derivative; and methods for treating or preventing cancer, a metabolic disorder or neurodegenerative disorder comprising the administration of an effective amount of a Fatty Acid Fumarate Derivative.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式