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1. 发明申请

WO2006096582A1 COMMUNICATING WITH AN IMPLANTED WIRELESS SENSOR 审中-公开
标题翻译：与植入式无线传感器通信
公开(公告)号：WO2006096582A1
公开(公告)日：2006-09-14
申请号：PCT/US2006/007790
申请日：2006-03-06
申请人： CARDIOMEMS, INC. , ALLEN, Mark , KROH, Jason , MILLER, Donald , ELLIS, Michael
发明人： ALLEN, Mark , KROH, Jason , MILLER, Donald , ELLIS, Michael
IPC分类号： A61B5/00
CPC分类号： G01R23/145 , A61B5/0002 , A61B5/0031 , A61B5/05 , A61B5/076 , A61B2560/0219 , A61B2560/0223 , G01F15/066 , G01R23/12 , H04L2027/0028 , H04L2027/0055 , H04L2027/0067
摘要： The present invention determines the resonant frequency of a sensor by adjusting the phase and frequency of an energizing signal until the frequency of the energizing signal matches the resonant frequency of the sensor. The system energizes the sensor with a low duty cycle, gated burst of RF energy having a predetermined frequency or set of frequencies and a predetermined amplitude. The energizing signal is coupled to the sensor via magnetic coupling and induces a current in the sensor which oscillates at the resonant frequency of the sensor. The system receives the ring down response of the sensor via magnetic coupling and determines the resonant frequency of the sensor, which is used to calculate the measured physical parameter. The system uses a pair of phase locked loops to adjust the phase and the frequency of the energizing signal.
摘要翻译：本发明通过调整激励信号的相位和频率来确定传感器的谐振频率，直到激励信号的频率与传感器的谐振频率匹配为止。系统以低占空比，具有预定频率或一组频率和预定幅度的RF能量的选通脉冲来激励传感器。激励信号通过磁耦合耦合到传感器，并在传感器中感应出电流，该电流以传感器的谐振频率振荡。系统通过磁耦合接收传感器的响铃响应，并确定传感器的谐振频率，用于计算测量的物理参数。该系统使用一对锁相环来调节激励信号的相位和频率。

2. 发明申请

WO2007008493A1 COUPLING LOOP, CABLE ASSEMBLY AND METHOD FOR POSITIONING COUPLING LOOP 审中-公开
标题翻译：耦合环，电缆组件和定位耦合环路的方法
公开(公告)号：WO2007008493A1
公开(公告)日：2007-01-18
申请号：PCT/US2006/026015
申请日：2006-06-30
申请人： CARDIOMEMS, INC. , KROH, Jason , ELLIS, Michael , MILLER, Donald , REFERMAT, Robert
发明人： KROH, Jason , ELLIS, Michael , MILLER, Donald , REFERMAT, Robert
IPC分类号： H04B5/00 , A61B5/00 , G01R33/00
CPC分类号： A61B5/02014 , A61B5/0031 , A61B5/064 , A61B5/07 , A61B2560/0219 , H01B11/20 , H04B5/0043 , Y10S128/903
摘要： A coupling loop or antenna is provided that can be used with a system that determines the resonant frequency of a sensor by adjusting the phase and frequency of an energizing signal until the frequency of the energizing signal matches the resonant frequency of the sensor. The coupling loop includes multiple loops. Preferably two tuned loops are used for transmitting the energizing signal to the sensor and an un-tuned loop is used for receiving the sensor signal from the sensor. A cable attached to the coupling loop provides maximum isolation between the energizing signal and the sensor signal by maximizing the distance between the coaxial cables that carry the signals and maintaining the relative positions of the coaxial cables throughout the cable assembly. Orientation features on the housing for the coupling loop and the sensor are provided to assist in positioning the coupling loop relative to the sensor to maximize the coupling between the sensor signal and the coupling loop.
摘要翻译：提供耦合环路或天线，其可以与通过调节激励信号的相位和频率来确定传感器的谐振频率的系统一起使用，直到通电信号的频率与传感器的谐振频率匹配。耦合回路包括多个回路。优选地，两个调谐回路用于将激励信号传输到传感器，并且未调谐回路用于从传感器接收传感器信号。连接到耦合回路的电缆通过使承载信号的同轴电缆之间的距离最大化并且保持同轴电缆在整个电缆组件中的相对位置来提供激励信号和传感器信号之间的最大隔离。提供用于耦合回路和传感器的壳体上的定向特征以帮助相对于传感器定位耦合回路，以使传感器信号和耦合回路之间的耦合最大化。

3. 发明授权

EP1902529B1 COUPLING LOOP, CABLE ASSEMBLY AND METHOD FOR POSITIONING COUPLING LOOP 失效
标题翻译： KOPPEL LOOP，线组件及方法用于定位的带环
公开(公告)号：EP1902529B1
公开(公告)日：2012-06-13
申请号：EP06774481.3
申请日：2006-06-30
申请人： CardioMems, Inc.
发明人： KROH, Jason , ELLIS, Michael , MILLER, Donald , REFERMAT, Robert
IPC分类号： H04B5/00 , A61B5/00 , G01R33/00
CPC分类号： A61B5/02014 , A61B5/0031 , A61B5/064 , A61B5/07 , A61B2560/0219 , H01B11/20 , H04B5/0043 , Y10S128/903
摘要： A coupling loop or antenna is provided that can be used with a system that determines the resonant frequency of a sensor by adjusting the phase and frequency of an energizing signal until the frequency of the energizing signal matches the resonant frequency of the sensor. The coupling loop includes multiple loops. Preferably two tuned loops are used for transmitting the energizing signal to the sensor and an un-tuned loop is used for receiving the sensor signal from the sensor. A cable attached to the coupling loop provides maximum isolation between the energizing signal and the sensor signal by maximizing the distance between the coaxial cables that carry the signals and maintaining the relative positions of the coaxial cables throughout the cable assembly. Orientation features on the housing for the coupling loop and the sensor are provided to assist in positioning the coupling loop relative to the sensor to maximize the coupling between the sensor signal and the coupling loop.

4. 发明申请

WO2008046230A1 PHOSPHOLIPID RECEPTORS AS TARGETS FOR ENHANCING DRUG PERMEABILITY TO SELECTED TISSUES 审中-公开
标题翻译：磷脂受体作为提高选择性组织药物渗透性的目标
公开(公告)号：WO2008046230A1
公开(公告)日：2008-04-24
申请号：PCT/CA2007/001868
申请日：2007-10-22
申请人： UNIVERSITY OF MANITOBA , UNIVERSITY OF NEBRASKA MEDICAL CENTER , MILLER, Donald , TOEWS, Myron , SAVANT, Sanjat , MAYHAN, Bill
发明人： MILLER, Donald , TOEWS, Myron , SAVANT, Sanjat , MAYHAN, Bill
IPC分类号： A61K31/661
CPC分类号： A61K31/661
摘要： A method for enhancing drug delivery to the brain in neurological disorders using lysophosphatidic acid (LPA) and sphingosine I phosphate (S1P) is herein described. Specifically, the permeability properties of LPA and S1P allow for a highly controlled and transient disruption of blood-brain barrier permeability. Thus these phospholipids can be used for delivering a wide variety of therapeutic, prophylactic or diagnostic agents to the brain.
摘要翻译：本文描述了使用溶血磷脂酸（LPA）和鞘氨醇I磷酸酯（S1P）在神经障碍中增强药物递送至脑的方法。具体来说，LPA和S1P的渗透性能使血脑屏障通透性受到高度的控制和瞬时破坏。因此，这些磷脂可用于将多种治疗性，预防性或诊断剂递送至脑。

5. 发明申请

WO2020102300A1 DIGITAL STEP SQUARE 审中-公开
公开(公告)号：WO2020102300A1
公开(公告)日：2020-05-22
申请号：PCT/US2019/061117
申请日：2019-11-13
申请人： MILLER, Donald
发明人： MILLER, Donald
IPC分类号： G01B3/00 , G01B3/04 , G01B3/06 , G01B3/08 , G01B3/56 , G01B5/00 , G01B5/02 , G01B5/24 , G01B5/25 , G01B7/30
摘要： A carpentry device including a main arm having a width and length configured to measure distances of an object. The main arm can include indicia markings on a face of the main arm for measuring distances of an object. The main arm can be formed from one or more sections configured to extend or retract in a longitudinal direction, including at least one supplemental arm extending from at least one connection point at an end of the main arm such that the at least one supplemental arm can rotate about the at least one connection point. A digital angle finder can be attached to the at least one connection point to display an angle between the at least one connection point and the main arm. A bubble level can be attached to the face of the main arm.

6. 发明申请

WO2011070154A1 A WATERJET ASSEMBLY COMPRISING A STRUCTURAL WATERJET NOZZLE 审中-公开
标题翻译：一个包含结构水喷嘴的水套装置
公开(公告)号：WO2011070154A1
公开(公告)日：2011-06-16
申请号：PCT/EP2010/069381
申请日：2010-12-10
申请人： FINECUT AB , MILLER, Donald
发明人： MILLER, Donald
IPC分类号： B24C1/04 , B24C5/02
CPC分类号： B24C5/02 , B24C1/045 , B24C5/04
摘要： The invention pertains to a waterjet assembly (61; 72; 101; 129; 151, 52) for an entrainment waterjet cutting head device (100; 120; 150; 155; 203). Said waterjet assembly (61; 72; 101; 129; 151, 52) comprises a passaged component (61; 72; 101; 129; 151) adapted to be connected to a source (2) of pressurised water and a waterjet nozzle (52) for converting water pressure energy to kinetic energy to form a high velocity waterjet (10), which waterjet nozzle (52) consists of superhard material and comprises a contracting bore (55). The passaged component (61; 72; 101; 129; 151) and the waterjet nozzle (52) are arranged such that pressurised water from the source (2) can flow through the passaged component (61; 72; 101; 129; 151) to and through the contracting bore (55) in the waterjet nozzle (52) to generate said high speed waterjet (10). In use of the waterjet assembly (61; 72; 101; 129; 151, 52), the outlet face of the passaged component (61; 72; 101; 129; 151) is sealingly forced against the upstream face of the waterjet nozzle (52).
摘要翻译：本发明涉及一种用于夹带水刀切割头装置（100; 120; 150; 155; 203）的水射流组件（61; 72; 101; 129; 151,52）。所述水刀组件（61; 72; 101; 129; 151,52）包括适于连接到加压水源（2）的传送部件（61; 72; 101; 129; 151）和水射流喷嘴），用于将水压能转换成动能以形成高速水刀（10），该水刀喷嘴（52）由超硬材料组成并且包括收缩孔（55）。传热部件（61; 72; 101; 129; 151）和水射流喷嘴（52）被布置成使得来自源（2）的加压水可以流过被传送部件（61; 72; 101; 129; 151）到达并穿过水刀喷嘴（52）中的收缩孔（55）以产生所述高速水刀（10）。在使用水刀组件（61; 72; 101; 129; 151,52）时，传送部件（61; 72; 101; 129; 151）的出口面被密封地压在水刀喷嘴的上游面 52）。

7. 发明授权

EP1876945B1 COMMUNICATING WITH AN IMPLANTED WIRELESS SENSOR 有权
标题翻译：已植入无线传感器之间的通信
公开(公告)号：EP1876945B1
公开(公告)日：2012-12-05
申请号：EP06737020.5
申请日：2006-03-06
申请人： CardioMems, Inc.
发明人： ALLEN, Mark , KROH, Jason , MILLER, Donald , ELLIS, Michael
IPC分类号： A61B5/00
CPC分类号： G01R23/145 , A61B5/0002 , A61B5/0031 , A61B5/05 , A61B5/076 , A61B2560/0219 , A61B2560/0223 , G01F15/066 , G01R23/12 , H04L2027/0028 , H04L2027/0055 , H04L2027/0067

8. 发明公开

EP1902529A1 COUPLING LOOP, CABLE ASSEMBLY AND METHOD FOR POSITIONING COUPLING LOOP 失效
标题翻译： KOPPEL LOOP，线组件及方法用于定位的带环
公开(公告)号：EP1902529A1
公开(公告)日：2008-03-26
申请号：EP06774481.3
申请日：2006-06-30
申请人： CardioMems, Inc.
发明人： KROH, Jason , ELLIS, Michael , MILLER, Donald , REFERMAT, Robert
IPC分类号： H04B5/00 , A61B5/00 , G01R33/00
CPC分类号： A61B5/02014 , A61B5/0031 , A61B5/064 , A61B5/07 , A61B2560/0219 , H01B11/20 , H04B5/0043 , Y10S128/903
摘要： A coupling loop or antenna is provided that can be used with a system that determines the resonant frequency of a sensor by adjusting the phase and frequency of an energizing signal until the frequency of the energizing signal matches the resonant frequency of the sensor. The coupling loop includes multiple loops. Preferably two tuned loops are used for transmitting the energizing signal to the sensor and an un-tuned loop is used for receiving the sensor signal from the sensor. A cable attached to the coupling loop provides maximum isolation between the energizing signal and the sensor signal by maximizing the distance between the coaxial cables that carry the signals and maintaining the relative positions of the coaxial cables throughout the cable assembly. Orientation features on the housing for the coupling loop and the sensor are provided to assist in positioning the coupling loop relative to the sensor to maximize the coupling between the sensor signal and the coupling loop.

9. 发明公开

EP1876945A1 COMMUNICATING WITH AN IMPLANTED WIRELESS SENSOR 有权
标题翻译：已植入无线传感器之间的通信
公开(公告)号：EP1876945A1
公开(公告)日：2008-01-16
申请号：EP06737020.5
申请日：2006-03-06
申请人： CardioMems, Inc.
发明人： ALLEN, Mark , KROH, Jason , MILLER, Donald , ELLIS, Michael
IPC分类号： A61B5/00
CPC分类号： G01R23/145 , A61B5/0002 , A61B5/0031 , A61B5/05 , A61B5/076 , A61B2560/0219 , A61B2560/0223 , G01F15/066 , G01R23/12 , H04L2027/0028 , H04L2027/0055 , H04L2027/0067
摘要： The present invention determines the resonant frequency of a sensor by adjusting the phase and frequency of an energizing signal until the frequency of the energizing signal matches the resonant frequency of the sensor. The system energizes the sensor with a low duty cycle, gated burst of RF energy having a predetermined frequency or set of frequencies and a predetermined amplitude. The energizing signal is coupled to the sensor via magnetic coupling and induces a current in the sensor which oscillates at the resonant frequency of the sensor. The system receives the ring down response of the sensor via magnetic coupling and determines the resonant frequency of the sensor, which is used to calculate the measured physical parameter. The system uses a pair of phase locked loops to adjust the phase and the frequency of the energizing signal.

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