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1. 发明申请

WO2010054359A3 REVERSE HYSTERESIS AND MODE SWITCHING FOR INTERMITTENT PACING THERAPY 审中-公开
标题翻译：间歇性起搏治疗的逆转迟滞和模式切换
公开(公告)号：WO2010054359A3
公开(公告)日：2010-10-21
申请号：PCT/US2009063830
申请日：2009-11-10
申请人： CARDIAC PACEMAKERS INC , ARCOT-KRISHNAMURTHY SHANTHA , SEIM GARY T , LEE KENT , DONG YANTING , SHUROS ALLAN C , WHITEHOUSE DAVID L
发明人： ARCOT-KRISHNAMURTHY SHANTHA , SEIM GARY T , LEE KENT , DONG YANTING , SHUROS ALLAN C , WHITEHOUSE DAVID L
IPC分类号： A61N1/362 , A61N1/365
CPC分类号： A61N1/3627 , A61N1/3688
摘要： Cardioprotective pre-excitation pacing may be applied to stress or de-stress a particular myocardial region delivering of pacing pulses in a manner that causes a dyssynchronous contraction. Such dyssynchronous contractions are responsible for the desired cardioprotective effects of pre-excitation pacing. A method and device for applying reverse hysteresis and mode switching to the delivery of such cardioprotective pacing are described.
摘要翻译：可以应用心脏保护性预激起搏来以导致非同步收缩的方式来施加或解除施加起搏脉冲的特定心肌区域。这种不同步收缩负责预激起搏所需的心脏保护作用。描述了用于将反向滞后和模式切换应用于递送这种心脏保护性起搏的方法和装置。

2. 发明专利

AU2015301958A1 Implantable medical device coating for wetting and microbial resistance 未知
公开(公告)号：AU2015301958A1
公开(公告)日：2017-02-09
申请号：AU2015301958
申请日：2015-08-10
申请人： CARDIAC PACEMAKERS INC
发明人： FOSTER ARTHUR J , GILK MATHEW L , MAILE KEITH R , DELANEY JR JOSEPH T , EPPIHIMER MICHAEL , SEIM GARY T
IPC分类号： A61N1/375 , A61N1/05 , A61N1/39
摘要： The present invention relates generally to the materials and methods for improving the wettability of an implantable medical device. More specifically, the invention relates to devices and methods for coating at least a portion of a medical device to improve wettability and reduce electrical impedance. Given the challenges of maintaining consistent and predictable electrical characteristics as implantable medical devices become smaller in size, there remains a continual need to improve wettability in an effort to improve medical outcomes.

3. 发明专利

AU2003268045A1 APPARATUS AND METHOD FOR SHOCK LEAD IMPEDANCE MEASUREMENT 未知
公开(公告)号：AU2003268045A1
公开(公告)日：2004-02-16
申请号：AU2003268045
申请日：2003-07-31
申请人： CARDIAC PACEMAKERS INC
发明人： PROPP HAL M , SEIM GARY T , FAVET MICHAEL L
IPC分类号： A61N1/08 , A61N1/37 , A61N1/39
摘要： An apparatus and method of automatically measuring the lead impedance of a high energy shock lead before delivery of high energy therapy used to treat heart arrhythmia. In one example, an impedance measurement circuit measures the impedance between electrodes in a plurality of pairs of electrodes. The measured lead electrode impedance is compared to a predetermined value to detect if the lead is shorted to another lead. If a high-energy shock electrode is shorted to another lead, a shorted lead indicator is set to a fault state. Based on the state of the shorted lead indicator, a processor prevents or allows the delivery of high energy therapy. By checking for a lead short before delivery of the therapy, all of the energy of the therapy is delivered to the patient rather than being bypassed by a shorted lead connection.

4. 发明专利

AU2011226953A1 Reverse pacing-mode switch 未知
公开(公告)号：AU2011226953A1
公开(公告)日：2011-10-20
申请号：AU2011226953
申请日：2011-09-29
申请人： CARDIAC PACEMAKERS INC
发明人： SEIM GARY T
IPC分类号： A61N1/368
摘要： Abstract A device comprises a cardiac contraction sensing circuit, a timer circuit, an electrical stimulation circuit, and a controller. The timer circuit provides a 5 time duration of an atrial-atrial interval between successive atrial contractions, a ventricular-ventricular interval between successive ventricular contractions, and an atrial-ventricular (A-V) interval between an atrial contraction and a same cardiac cycle ventricular contraction. The controller includes an event detection module and a pacing module. The event detection module is configured for 10 determining whether A-V block events are sustained over multiple cardiac cycles. The pacing module is configured for providing pacing therapy according to a primary pacing mode that includes AAI(R) mode with independent VVI backup mode, and for switching the pacing therapy to a secondary pacing mode if A-V block events are sustained over multiple cardiac cycles. Other devices 15 and methods are described. SENSING ATRIAL-ATRIAL (A-A) INTERVALS BETWEEN SUCCESSIVE ATRIAL CONTRACTIONS IN AN ATRIUM AND VENTRICULAR-VENTRICULAR (V-V) INTERVALS BETWEEN SUCCESSIVE VENTRICULAR CONTRACTIONS IN A VENTRICLE PROVIDING PACING THERAPY ACCORDING TO A PRIMARY PACING MODE, THE THERAPY INCLUDING PACING THE ATRIUM ACCORDING TO AAI MODE AND INDEPENDENTLY PACING THE VENTRICLE ACCORDING TO WI MODE DETERMINING WHETHER ATRIAL-VENTRICULAR (A-V) BLOCK EVENTS ARE SUSTAINED OVER MULTIPLE CARDIAC CYCLES SWITCHING THE PACING THERAPY TO A SECONDARY PACING MODE IF A-V BLOCK EVENTS ARE SUSTAINED OVER MULTIPLE CARDIAC CYCLES

5. 发明专利

DE69941793D1 未知
公开(公告)号：DE69941793D1
公开(公告)日：2010-01-21
申请号：DE69941793
申请日：1999-10-27
申请人： CARDIAC PACEMAKERS INC
发明人： HAEFNER PAUL A , SEIM GARY T
IPC分类号： A61N1/37
摘要： A system for automatically adjusting a sensing threshold in a cardiac rhythm management device (105), the system comprising means for increasing an atrial sensing threshold (405) during a time period (t 3 , t 4 ; t 7 , t 8 ) in response to a ventricular depolarization (420A) or the delivery of a ventricular pace puls (420B) and/or means for increasing a ventricular sensing threshold (505) during a time period (t 3 , t 4 ; t 7 , t 8 ) in response to an atrial depolarization (415A) or the delivery of an atrial pace pulse (415B).

6. 发明专利

ES2326308T3 SISTEMA GENERADOR DE PULSOS. 未知
公开(公告)号：ES2326308T3
公开(公告)日：2009-10-07
申请号：ES01968846
申请日：2001-09-14
申请人： CARDIAC PACEMAKERS INC
发明人： CHEN VICTOR T , SEIM GARY T , MORRIS MILTON M
IPC分类号： A61N1/39 , A61N1/362 , A61N1/368
摘要： Un sistema generador de pulsos, que comprende un primer electrodo (606), un sensor (656) para detectar una señal intrínseca por medio del primer electrodo, un generador (640) de pulsos que produce pulsos para ser administrados por medio del primer electrodo, un controlador (644) de la frecuencia del pulso acoplado al generador de pulsos, en el que el generador de pulsos está controlado por el controlador de la frecuencia del pulso para generar pulsos a una frecuencia de pulso, en el que la frecuencia del pulso tiene un valor inicial, y un detector de frecuencia intrínseca acoplado al controlador de la frecuencia del pulso, y en el que el sistema generador de pulsos está caracterizado porque: el controlador de la frecuencia del pulso disminuye la frecuencia del pulso desde el valor inicial hasta que se detecta una despolarización intrínseca en la señal intrínseca por medio del detector de la frecuencia intrínseca, en el que el detector de la frecuencia intrínseca determina una frecuencia intrínseca utilizando la despolarización intrínseca detectada, y en el que, entonces, el controlador de la frecuencia del pulso aumenta la frecuencia del pulso por encima de la frecuencia intrínseca.

7. 发明专利

AU1325500A Cardiac rhythm management system with cross-chamber soft blanking 未知
公开(公告)号：AU1325500A
公开(公告)日：2000-05-15
申请号：AU1325500
申请日：1999-10-27
申请人： CARDIAC PACEMAKERS INC
发明人： HAEFNER PAUL A , SEIM GARY T
IPC分类号： A61N1/37
摘要： A system for automatically adjusting a sensing threshold in a cardiac rhythm management device (105), the system comprising means for increasing an atrial sensing threshold (405) during a time period (t 3 , t 4 ; t 7 , t 8 ) in response to a ventricular depolarization (420A) or the delivery of a ventricular pace puls (420B) and/or means for increasing a ventricular sensing threshold (505) during a time period (t 3 , t 4 ; t 7 , t 8 ) in response to an atrial depolarization (415A) or the delivery of an atrial pace pulse (415B).

8. 发明专利

AU2011226953B2 Reverse pacing-mode switch 未知
公开(公告)号：AU2011226953B2
公开(公告)日：2013-07-25
申请号：AU2011226953
申请日：2011-09-29
申请人： CARDIAC PACEMAKERS INC
发明人： SEIM GARY T
IPC分类号： A61N1/368
摘要： Abstract A device comprises a cardiac contraction sensing circuit, a timer circuit, an electrical stimulation circuit, and a controller. The timer circuit provides a 5 time duration of an atrial-atrial interval between successive atrial contractions, a ventricular-ventricular interval between successive ventricular contractions, and an atrial-ventricular (A-V) interval between an atrial contraction and a same cardiac cycle ventricular contraction. The controller includes an event detection module and a pacing module. The event detection module is configured for 10 determining whether A-V block events are sustained over multiple cardiac cycles. The pacing module is configured for providing pacing therapy according to a primary pacing mode that includes AAI(R) mode with independent VVI backup mode, and for switching the pacing therapy to a secondary pacing mode if A-V block events are sustained over multiple cardiac cycles. Other devices 15 and methods are described. SENSING ATRIAL-ATRIAL (A-A) INTERVALS BETWEEN SUCCESSIVE ATRIAL CONTRACTIONS IN AN ATRIUM AND VENTRICULAR-VENTRICULAR (V-V) INTERVALS BETWEEN SUCCESSIVE VENTRICULAR CONTRACTIONS IN A VENTRICLE PROVIDING PACING THERAPY ACCORDING TO A PRIMARY PACING MODE, THE THERAPY INCLUDING PACING THE ATRIUM ACCORDING TO AAI MODE AND INDEPENDENTLY PACING THE VENTRICLE ACCORDING TO WI MODE DETERMINING WHETHER ATRIAL-VENTRICULAR (A-V) BLOCK EVENTS ARE SUSTAINED OVER MULTIPLE CARDIAC CYCLES SWITCHING THE PACING THERAPY TO A SECONDARY PACING MODE IF A-V BLOCK EVENTS ARE SUSTAINED OVER MULTIPLE CARDIAC CYCLES

9. 发明专利

ES2376516T3 SISTEMA GENERADOR DE IMPULSOS. 未知
公开(公告)号：ES2376516T3
公开(公告)日：2012-03-14
申请号：ES09158972
申请日：2001-09-14
申请人： CARDIAC PACEMAKERS INC
发明人： CHEN VICTOR T , SEIM GARY T , MORRIS MILTON M
IPC分类号： A61N1/39 , A61N1/362 , A61N1/368
摘要： Un sistema que comprende: un circuito sensor implantable de señales cardiacas, configurado para proporcionar una señal cardiaca detectada procedente de una aurícula; y un circuito de control, acoplado en comunicación al circuito sensor de señales cardiacas, que incluye: un detector de la frecuencia intrínseca configurado para detectar una frecuencia de contracción intrínseca auricular usando la señal cardiaca detectada; y un generador de impulsos de estimulación configurado para: suministrar energía de estimulación a un electrodo conformado y dimensionado para su colocación en una aurícula o cerca de la misma; proporcionar después impulsos de estimulación a la aurícula con una frecuencia inicial, y estando caracterizado el sistema porque el generador de impulsos de estimulación está configurado, además, para: en respuesta, suministrar energía de desfibrilación a la aurícula; disminuir una frecuencia de estimulación a partir de la frecuencia inicial hasta que un detector de la frecuencia intrínseca detecte una frecuencia intrínseca; y aumentar la frecuencia de estimulación por encima de la frecuencia intrínseca detectada

10. 发明专利

AU2008239688A1 Reverse pacing-mode switch 未知
公开(公告)号：AU2008239688A1
公开(公告)日：2008-10-23
申请号：AU2008239688
申请日：2008-04-10
申请人： CARDIAC PACEMAKERS INC
发明人： SEIM GARY T
IPC分类号： A61N1/368

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