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1. 发明申请

WO2011081697A1 APPARATUS TO SELECTIVELY INCREASE MEDICAL DEVICE LEAD INNER CONDUCTOR INDUCTANCE 审中-公开
标题翻译：选择性增加医疗器械引导内导体电感的设备
公开(公告)号：WO2011081697A1
公开(公告)日：2011-07-07
申请号：PCT/US2010/052819
申请日：2010-10-15
申请人： CARDIAC PACEMAKERS, INC. , STUBBS, Scott R. , STAHMANN, Jeffrey E. , FOSTER, Arthur J. , KUNKEL, Ronald W.
发明人： STUBBS, Scott R. , STAHMANN, Jeffrey E. , FOSTER, Arthur J. , KUNKEL, Ronald W.
IPC分类号： A61N1/37
CPC分类号： A61N1/056 , A61N1/086
摘要： A medical device lead includes an insulative lead body, outer and inner conductive coils, and a flexible core assembly. The outer conductive coil extends through the lead body and is coupled to a first electrode at a distal end of the outer conductive coil. The inner conductive coil extends coaxially with the outer conductive coil, is coupled to a second electrode at a distal end of the inner conductive coil, and includes a central lumen. The flexible core assembly is disposed in the central lumen and is comprised of a material that has a saturation magnetization of at least about 1.5 T and a relative permeability of greater than one. The flexible core assembly includes a positioning interface configured for manipulation of the flexible core assembly such that the flexible core assembly translates through the central lumen during insertion and extraction of the flexible core assembly.
摘要翻译：医疗器械引线包括绝缘引线体，外部和内部导电线圈以及柔性芯组件。外部导电线圈延伸穿过引线体并且在外部导电线圈的远端处耦合到第一电极。与外部导电线圈同轴地延伸的内部导电线圈耦合到内部导电线圈的远端处的第二电极，并且包括中央腔。柔性芯组件设置在中心腔中，并且由具有至少约1.5T的饱和磁化强度和大于1的相对磁导率的材料构成。柔性芯组件包括配置用于操纵柔性芯组件的定位接口，使得柔性芯组件在插入和拔出柔性芯组件期间通过中心腔平移。

2. 发明申请

WO2012067713A1 INSULATIVE STRUCTURE FOR MRI COMPATIBLE LEADS 审中-公开
标题翻译： MRI兼容导联的绝缘结构
公开(公告)号：WO2012067713A1
公开(公告)日：2012-05-24
申请号：PCT/US2011/052684
申请日：2011-09-22
申请人： CARDIAC PACEMAKERS, INC. , STAHMANN, Jeffrey E. , STUBBS, Scott R. , FOSTER, Arthur J.
发明人： STAHMANN, Jeffrey E. , STUBBS, Scott R. , FOSTER, Arthur J.
IPC分类号： A61N1/08
CPC分类号： A61N1/0563 , A61N1/086
摘要： A medical device lead includes a proximal connector, an insulative lead body extending distally from the proximal connector. The proximal connector is configured to couple the lead to a pulse generator. A first conductive coil is coupled to the proximal connector and extends through the lead body. The first conductive coil is coupled to a first electrode at a distal end of the first conductive coil. A first magnetically impregnated polymer layer is adjacent the first conductive coil.
摘要翻译：医疗装置引线包括近端连接器，从近端连接器向远侧延伸的绝缘引线体。近端连接器被配置为将引线耦合到脉冲发生器。第一导电线圈耦合到近端连接器并延伸穿过引线体。第一导电线圈在第一导电线圈的远端耦合到第一电极。第一磁性浸渍聚合物层与第一导电线圈相邻。

3. 发明申请

WO2013025299A1 MEDICAL DEVICE LEAD WITH CONDUCTOR FRACTURE PREDICTION 审中-公开
标题翻译：医疗设备引导与导线断裂预测
公开(公告)号：WO2013025299A1
公开(公告)日：2013-02-21
申请号：PCT/US2012/046714
申请日：2012-07-13
申请人： CARDIAC PACEMAKERS, INC. , FOSTER, Arthur J. , PERREY, Christopher , STAHMANN, Jeffrey E. , STUBBS, Scott R.
发明人： FOSTER, Arthur J. , PERREY, Christopher , STAHMANN, Jeffrey E. , STUBBS, Scott R.
IPC分类号： A61N1/375 , A61N1/08
CPC分类号： A61N1/375 , A61N1/048 , A61N1/0488 , A61N1/37 , A61N1/3752 , A61N2001/083
摘要： A medical device lead includes a lead body having a proximal end and a distal end. The proximal end is configured for connection to a pulse generator. One or more electrodes are at a distal end of the lead body, and a lead conductor extends through the lead body and is electrically coupled to at least one of the one or more electrodes. The conductor is configured to deliver electrical signals between the proximal end and the at least one of the one or more electrodes. A sacrificial conductor extends through the lead body adjacent to lead conductor and is configured to fail at a lower stress than the lead conductor.
摘要翻译：医疗器械引线包括具有近端和远端的引线主体。近端被配置为连接到脉冲发生器。一个或多个电极位于引线主体的远端，并且引线导体延伸穿过引线主体并且电耦合到所述一个或多个电极中的至少一个。导体被配置为在近端和所述一个或多个电极中的至少一个之间递送电信号。牺牲导体延伸穿过与引线导体相邻的引线体，并且被配置为在比引线导体更低的应力下失效。

4. 发明申请

WO2012078228A1 IMPLANTABLE LEAD INCLUDING A SPARK GAP TO REDUCE HEATING IN MRI ENVIRONMENTS 审中-公开
标题翻译：可塑性领先，包括降低MRI环境加热的火山口
公开(公告)号：WO2012078228A1
公开(公告)日：2012-06-14
申请号：PCT/US2011/052541
申请日：2011-09-21
申请人： CARDIAC PACEMAKERS, INC. , STUBBS, Scott R. , FOSTER, Arthur J.
发明人： STUBBS, Scott R. , FOSTER, Arthur J.
IPC分类号： A61N1/05 , A61N1/08
CPC分类号： A61N1/0563 , A61N1/086
摘要： A medical device lead includes a proximal connector configured to couple the lead to a pulse generator, and an insulative lead body extending distally from the proximal connector. A first lead conductor is coupled to the proximal connector and extends through the lead body. The medical device lead also includes a distal defibrillation electrode. A first spark gap is connected between the first lead conductor and the distal defibrillation electrode and has a breakdown voltage that prevents transmission of magnetic resonance imaging (MRI) induced signals from the first lead conductor to the distal defibrillation electrode in an MRI environment and allows transmission of therapy signals to the distal defibrillation electrode.
摘要翻译：医疗器械引线包括被配置为将引线耦合到脉冲发生器的近端连接器以及从近端连接器向远端延伸的绝缘引线体。第一引线导体耦合到近端连接器并且延伸穿过引线体。医疗器械引线还包括远端除颤电极。第一火花隙连接在第一引线导体和远端除颤电极之间，并且具有防止磁共振成像（MRI）感应信号从MRI环境中从第一引线导体传输到远端除颤电极的击穿电压，并允许传输的治疗信号到远端除颤电极。

5. 发明申请

WO2011071597A1 IMPLANTABLE MEDICAL DEVICE WITH AUTOMATIC TACHYCARDIA DETECTION AND CONTROL IN MRI ENVIRONMENTS 审中-公开
标题翻译： MRI环境中具有自动TACHYCARDIA检测和控制的可植入医疗器械
公开(公告)号：WO2011071597A1
公开(公告)日：2011-06-16
申请号：PCT/US2010/053202
申请日：2010-10-19
申请人： CARDIAC PACEMAKERS, INC. , STUBBS, Scott R. , GILKERSON, James O. , DOSHI, Hiten J. , SCHUSTER, Diane
发明人： STUBBS, Scott R. , GILKERSON, James O. , DOSHI, Hiten J. , SCHUSTER, Diane
IPC分类号： A61N1/37 , A61N1/08 , A61N1/362 , A61N1/39
CPC分类号： A61N1/3962 , A61N1/056 , A61N1/086 , A61N1/37 , A61N1/3718
摘要： An implantable medical device (IMD) includes a lead having one or more sensing electrodes and one or more therapy delivery electrodes, and a sensor configured to detect the presence of static and time-varying scan fields in a magnetic resonance imaging (MRI) environment. A controller, in electrical communication with the lead and the sensor, is configured to process signals related to tachycardia events sensed via the one or more sensing electrodes and to deliver pacing and shock therapy signals via the one or more therapy delivery electrodes. The controller compares the sensed static and time-varying scan fields to static and time-varying scan field thresholds. The controller controls delivery of anti-tachycardia pacing and shock therapy signals as a function of the detected tachycardia events, the comparison of the sensed static scan field to the static scan field threshold, and the comparison of the time-varying scan fields to the time-varying scan field thresholds.
摘要翻译：可植入医疗装置（IMD）包括具有一个或多个感测电极和一个或多个治疗递送电极的引线，以及配置成检测磁共振成像（MRI）环境中静态和时变扫描场的存在的传感器。与引线和传感器电连通的控制器被配置为处理与通过一个或多个感测电极感测的心动过速相关的信号，并且经由一个或多个治疗传递电极输送起搏和休克治疗信号。控制器将感测到的静态和时变扫描场与静态和时变扫描场阈值进行比较。控制器控制作为检测到的心动过速事件的函数的抗心动过速起搏和休克治疗信号的传递，感测的静态扫描场与静态扫描场阈值的比较，以及时变扫描场与时间的比较 - 扫描场阈值变化。

6. 发明申请

WO2011084510A1 SYSTEM AND METHOD TO AUTHORIZE RESTRICTED FUNCTIONALITY 审中-公开
标题翻译：授权限制功能的系统和方法
公开(公告)号：WO2011084510A1
公开(公告)日：2011-07-14
申请号：PCT/US2010/060561
申请日：2010-12-15
申请人： STUBBS, Scott R. , DOSHI, Hiten J. , CARDIAC PACEMAKERS, INC.
发明人： STUBBS, Scott R. , DOSHI, Hiten J.
IPC分类号： G06F19/00
CPC分类号： G16H40/40 , G06F19/00 , G16H40/63 , G16H80/00
摘要： Embodiments of the invention are related to medical systems and methods for controlling authorization of restricted functionality, amongst other things. In an embodiment, the invention includes a medical system including an external medical device programmer comprising control circuitry and a wireless communications module for sending instructions selected from a set of instructions wirelessly to a specific implanted medical device. In an embodiment, the external medical device programmer can be configured to initiate a transfer of verifying data to a remote key authority requesting permission if the user input directs delivery of restricted instructions to the specific implanted medical device, the verifying data including information regarding the specific implanted medical device. Other embodiments are also included herein.
摘要翻译：本发明的实施例涉及用于控制限制功能的授权的医疗系统和方法等。在一个实施例中，本发明包括医疗系统，其包括外部医疗设备编程器，其包括控制电路和无线通信模块，用于将无线地从一组指令中选择的指令发送到特定的植入式医疗设备。在一个实施例中，外部医疗设备编程器可以被配置为：如果用户输入将限制指令的传递指导给特定的植入式医疗设备，则验证数据向远程密钥管理机构请求许可的传送，验证数据包括关于具体的植入医疗器械。本文还包括其它实施例。

7. 发明申请

WO2010096138A1 SYSTEMS AND METHODS FOR PROVIDING ARRHYTHMIA THERAPY IN MRI ENVIRONMENTS 审中-公开
标题翻译：在MRI环境中提供ARRHYTHMIA治疗的系统和方法
公开(公告)号：WO2010096138A1
公开(公告)日：2010-08-26
申请号：PCT/US2009/068314
申请日：2009-12-16
申请人： CARDIAC PACEMAKERS, INC. , STUBBS, Scott R. , GILKERSON, James O. , SCHUSTER, Diane
发明人： STUBBS, Scott R. , GILKERSON, James O. , SCHUSTER, Diane
IPC分类号： A61N1/362 , A61N1/39
CPC分类号： A61N1/3931 , A61N1/3688 , A61N1/37 , A61N1/3718
摘要： Systems and methods for arrhythmia therapy in MRI environments are disclosed. Various systems disclosed utilize ATP therapy rather than ventricular shocks when patients are subjected to electromagnetic fields in an MRI scanner bore and shock therapy is not available. As the patient is moved out from within the scanner bore and away from the MRI scanner, the magnetic fields diminish in strength eventually allowing a high voltage capacitor within the IMD to charge if necessary. The system may detect when the electromagnetic fields no longer interfere with the shock therapy and will transition the IMD back to a normal operational mode where shock therapy can be delivered. Then, if the arrhythmia still exists, the system will carry out all of the system's prescribed operations, including the delivery of electric shocks to treat the arrhythmia.
摘要翻译：公开了MRI环境中心律失常治疗的系统和方法。所公开的各种系统利用ATP治疗而不是心室休克，当患者在MRI扫描器孔中经受电磁场并且不能使用休克疗法时。当患者从扫描仪孔内移出并远离MRI扫描仪时，磁场的强度减弱，最终允许IMD内的高电压电容器根据需要进行充电。该系统可以检测何时电磁场不再干扰休克疗法，并将IMD转移回正常的操作模式，其中可以提供休克疗法。那么，如果心律失常仍然存在，系统将执行系统的所有规定的操作，包括交付电击治疗心律失常。

8. 发明申请

WO2010047893A1 SYSTEMS AND METHODS TO DETECT IMPLANTABLE MEDICAL DEVICE CONFIGURATION CHANGES AFFECTING MRI CONDITIONAL SAFETY 审中-公开
标题翻译：检测影响MRI条件安全的可植入医疗设备配置变化的系统和方法
公开(公告)号：WO2010047893A1
公开(公告)日：2010-04-29
申请号：PCT/US2009/056843
申请日：2009-09-14
申请人： CARDIAC PACEMAKERS, INC. , STUBBS, Scott R. , SCHUSTER, Diane , BOBGAN, Jean M. , BERGER, Ronald D.
发明人： STUBBS, Scott R. , SCHUSTER, Diane , BOBGAN, Jean M. , BERGER, Ronald D.
IPC分类号： A61N1/362
CPC分类号： A61N1/37 , A61N1/025 , A61N1/086 , A61N1/362 , A61N1/3718 , A61N2001/083
摘要： Systems and methods for checking the connection of a lead to an implantable medical device implanted within a patient's body are disclosed. An illustrative method includes measuring at least one characteristic associated with the lead connection to the implantable medical device prior to an MRI scan. The method further includes comparing the at least one measured characteristic with a threshold parameter programmed within the implantable medical device. The method further includes setting a flag in the implantable medical device upon the at least one measured characteristic satisfying at least one condition associated with the threshold parameter for a predetermined period of time. The flag indicates a disconnection of the lead from the implantable medical device.
摘要翻译：公开了用于检查引线与植入患者体内的可植入医疗装置的连接的系统和方法。示例性方法包括在MRI扫描之前测量与可植入医疗装置的引线连接相关联的至少一个特性。该方法还包括将至少一个测量特征与在可植入医疗装置内编程的阈值参数进行比较。所述方法还包括在所述至少一个测量特征满足与所述阈值参数相关联的至少一个条件达预定时间段时，在所述可植入医疗装置中设置标志。该标志指示铅从可植入医疗装置断开。

9. 发明申请

WO2011090594A1 SENSING DURING MAGNETIC RESONANCE IMAGING 审中-公开
标题翻译：磁共振成像期间的感应
公开(公告)号：WO2011090594A1
公开(公告)日：2011-07-28
申请号：PCT/US2010/060070
申请日：2010-12-13
申请人： CARDIAC PACEMAKERS, INC. , STUBBS, Scott R. , LI, Yingbo , BOCEK, Joesph M.
发明人： STUBBS, Scott R. , LI, Yingbo , BOCEK, Joesph M.
IPC分类号： A61N1/37 , G06F19/00 , A61B5/055 , G01R33/567
CPC分类号： A61N1/37 , A61B5/0402 , A61B5/055 , A61B5/7203 , A61N1/3718 , G01R33/283 , G06F19/00 , G06F19/3418 , G16H40/63
摘要： Physiologic information can be received from a subject during a portion of a magnetic resonance imaging (MRI) session using a sensing circuit of an implantable medical device (IMD). An indication of an active MRI scan can be received, and a time period to inhibit use of physiological information from the subject can be determined following the received indication of the active MRI scan.
摘要翻译：在使用可植入医疗装置（IMD）的感测电路的磁共振成像（MRI）会话的一部分期间，可以从受试者接收生理信息。可以接收主动MRI扫描的指示，并且可以在接收到的主动MRI扫描的指示之后确定抑制来自受试者的生理信息的使用的时间段。

10. 发明公开

EP2640458A1 INSULATIVE STRUCTURE FOR MRI COMPATIBLE LEADS 有权
标题翻译：绝缘结构的MRI兼容PADS
公开(公告)号：EP2640458A1
公开(公告)日：2013-09-25
申请号：EP11764429.4
申请日：2011-09-22
申请人： Cardiac Pacemakers, Inc.
发明人： STAHMANN, Jeffrey E. , STUBBS, Scott R. , FOSTER, Arthur J.
IPC分类号： A61N1/08
CPC分类号： A61N1/0563 , A61N1/086
摘要： A medical device lead includes a proximal connector, an insulative lead body extending distally from the proximal connector. The proximal connector is configured to couple the lead to a pulse generator. A first conductive coil is coupled to the proximal connector and extends through the lead body. The first conductive coil is coupled to a first electrode at a distal end of the first conductive coil. A first magnetically impregnated polymer layer is adjacent the first conductive coil.

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