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1. 发明申请

WO2003092805A3 METHOD AND APPARATUS FOR DETECTING OSCILLATIONS IN CARDIAC RHYTHM 审中-公开
公开(公告)号：WO2003092805A3
公开(公告)日：2003-11-13
申请号：PCT/US2003/014031
申请日：2003-05-02
申请人： CARDIAC PACEMAKERS, INC.
发明人： PASTORE, Joseph, M. , LINCOLN, William, C. , CARLSON, Gerrard, M. , ZHU, Qingsheng , DING, Jiang , SALO, Rodney, W. , NI, Quan
IPC分类号： A61N1/365
摘要： A cardiac rhythm management device is configured to detect mechanical oscillations in cardiac rhythm. Upon detection of such oscillations, the device may adjust its operating behavior to compensate for the deleterious effects of the condition.

2. 发明申请

WO2003053511A3 CARDIAC RHYTHM MANAGEMENT SYSTEM 审中-公开
公开(公告)号：WO2003053511A3
公开(公告)日：2003-07-03
申请号：PCT/US2002/040909
申请日：2002-12-20
申请人： CARDIAC PACEMAKERS, INC.
发明人： SPINELLI, Julio, C. , ZHU, Qingsheng , STAHMANN, Jeffrey, E. , KRAMER, Andrew, P.
IPC分类号： A61N1/362
摘要： A system, method, or device classifies an arrhythmia according to the temporal order in which a depolarization wave associated with a particular heart contraction is received at a plurality of electrodes. One or more antiarrhythmia therapies is mapped to each arrhythmia classification. When a particularly classified arrhythmia is detected, the correspondingly mapped therapy list is selected and an appropriate antiarrhythmia therapy delivered. In one example, the particular therapy delivered in response to an arrhythmia depends at least in part on its historical success in treating arrhythmias of that classification.

3. 发明申请

WO2005030325A1 DEMAND-BASED CARDIAC FUNCTION THERAPY 审中-公开
标题翻译：基于需求的心脏功能治疗
公开(公告)号：WO2005030325A1
公开(公告)日：2005-04-07
申请号：PCT/US2004/031062
申请日：2004-09-23
申请人： CARDIAC PACEMAKERS, INC. , KENKNIGHT, Bruce, H. , ZHU, Qingsheng
发明人： KENKNIGHT, Bruce, H. , ZHU, Qingsheng
IPC分类号： A61N1/362
CPC分类号： A61N1/3627 , A61N1/36521 , A61N1/3684
摘要： A method and device for delivering cardiac function therapy on a demand basis. An implantable device for delivering cardiac function therapy (200) is programmed to suspend such therapy (201) at periodic intervals or upon command from an external programmer. Measurements related to hemodynamic performance are then taken using one or more sensing modalities incorporated into the device (203) . Based upon these measurements, the device uses a decision algorithm to determine whether further delivery of the cardiac function therapy is warranted (206).
摘要翻译：一种用于在需求的基础上提供心脏功能治疗的方法和装置。用于递送心脏功能治疗（200）的可植入装置被编程为以周期性间隔或者来自外部编程器的命令暂停这种治疗（201）。然后使用结合到装置（203）中的一个或多个感测模式来进行与血液动力学性能相关的测量。基于这些测量，该装置使用决策算法来确定是否需要进一步递送心脏功能治疗（206）。

4. 发明申请

WO2004060483A1 METHOD AND APPARATUS FOR MONITORING OF DIASTOLIC HEMODYNAMICS 审中-公开
标题翻译：用于监测白血病HEMODY动力学的方法和装置
公开(公告)号：WO2004060483A1
公开(公告)日：2004-07-22
申请号：PCT/US2003/041481
申请日：2003-12-30
申请人： CARDIAC PACEMAKERS, INC.
发明人： SIEJKO, Krzysztof, Z. , ZHU, Qingsheng , CARLSON, Gerrard, M.
IPC分类号： A61N1/365
CPC分类号： A61B5/02028 , A61B7/00 , A61N1/36514 , A61N1/36528
摘要： A cardiac rhythm management system provides for ambulatory monitoring of hemodynamic performance based on quantitative measurements of heart sound related parameters for diagnostic and therapeutic purposes. Monitoring of such heart sound related parameters allows the cardiac rhythm management system to determine a need for delivering a therapy and/or therapy parameter adjustments based on conditions of a heart. This monitoring also allows a physician to observe or assess the hemodynamic performance for diagnosing and making therapeutic decisions. Because the conditions of the heart may fluctuate and may deteriorate significantly between physician visits, the ambulatory monitoring, performed on a continuous or periodic basis, ensures a prompt response by the cardiac rhythm management system that may save a life, prevent hospitalization, or prevent further deterioration of the heart.
摘要翻译：心律管理系统基于用于诊断和治疗目的的心音相关参数的定量测量，提供对血液动力学性能的动态监测。监测这种心音相关参数允许心律管理系统基于心脏的情况来确定输送治疗和/或治疗参数调整的需要。该监测还允许医师观察或评估用于诊断和作出治疗决定的血液动力学性能。由于心脏的状况可能波动，并且可能在医师访问之间显着恶化，所以在连续或周期性的基础上进行的动态监测可确保心律管理系统能够节省生命，预防住院或进一步防止心律失常的迅速反应心脏恶化

5. 发明申请

WO2004059551A2 ADVANCED PATIENT MANAGEMENT FOR CORRELATING DATA 审中-公开
标题翻译：相关数据的高级患者管理
公开(公告)号：WO2004059551A2
公开(公告)日：2004-07-15
申请号：PCT/US2003/040034
申请日：2003-12-16
申请人： CARDIAC PACEMAKERS, INC.
发明人： STAHMANN, Jeffrey, E. , HATLESTAD, John , ZHU, Qingsheng
IPC分类号： G06F17/60
CPC分类号： A61B5/02405 , A61B5/0006 , A61B5/0031 , A61B5/02055 , A61B5/0215 , A61B5/024 , A61B5/0464 , A61B5/0809 , A61B5/0816 , A61B5/0833 , A61B5/16 , A61B5/205 , A61B5/743 , A61B5/7435 , A61B5/7475 , A61B7/00 , A61B2560/0242 , A61B2560/0271 , G06F19/00
摘要： Systems, devices and methods for identifying, displaying and assisting in correlating health-related data are disclosed. One aspect is a programmable device having machine executable instructions for performing a method for use in correlating data to manage a patient's health. In various embodiments, data related to the patient's health is acquired. The acquired data includes one or more trended health-related parameters, and at least one of one or more predetermined health-related events and one or more health-related alerts. Correlations are identified. The one or more trended health-related parameters and the at least one of the one or more predetermined health-related events and the one or more health-related alerts establish a causal relationship between the acquired data and the patient's health. Other aspects and embodiments are provided herein.
摘要翻译：公开了用于识别，显示和协助关联健康相关数据的系统，设备和方法。一个方面是具有机器可执行指令的可编程设备，用于执行用于关联数据以管理患者健康的方法。在各种实施例中，获得与患者健康有关的数据。所获取的数据包括一个或多个趋势健康相关参数，以及一个或多个预定健康相关事件和一个或多个健康相关警报中的至少一个。确定相关性。所述一个或多个趋势健康相关参数以及所述一个或多个预定健康相关事件和所述一个或多个健康相关警报中的至少一个建立所获取的数据与所述患者健康之间的因果关系。本文提供了其它方面和实施例。

6. 发明申请

WO2004011088A1 APPARATUS AND METHOD FOR OPTIMIZING CARDIAC PUMPING PERFORMANCE 审中-公开
标题翻译：优化心脏泵送性能的装置和方法
公开(公告)号：WO2004011088A1
公开(公告)日：2004-02-05
申请号：PCT/US2003/022989
申请日：2003-07-24
申请人： CARDIAC PACEMAKERS, INC.
发明人： DING, Jiang , YU, Yinghong , ZHU, Qingsheng
IPC分类号： A61N1/365
CPC分类号： A61N1/36542 , A61N1/36514 , A61N1/3682 , A61N1/3684
摘要： A cardiac rhythm and function management device configured to automatically adjust stimulation parameters used in delivering cardiac resynchronization therapy. Mechanical contraction intervals are measured using appropriately placed accelerometers and compared with optimum values. The stimulation parameters can then be adjusted accordingly in a manner that moves the mechanical contraction intervals toward their optimum values.
摘要翻译：心律和功能管理装置被配置为自动调整用于递送心脏再同步治疗的刺激参数。使用适当放置的加速度计测量机械收缩间隔，并与最佳值进行比较。然后可以以使机械收缩间隔向其最佳值移动的方式相应地调节刺激参数。

7. 发明申请

WO2005046472A1 DETECTION OF CONGESTION FROM MONITORING PATIENT RESPONSE TO A RECUMBENT POSITION 审中-公开
标题翻译：检测患者对重要位置的反应
公开(公告)号：WO2005046472A1
公开(公告)日：2005-05-26
申请号：PCT/US2003/032553
申请日：2003-10-14
申请人： CARDIAC PACEMAKERS, INC.
发明人： HATLESTAD, John , ZHU, Qingsheng , STAHMANN, Jeffrey, E.
IPC分类号： A61B5/053
CPC分类号： A61B5/1116 , A61B5/02 , A61B5/0535 , A61B5/0809 , A61B5/1135 , A61B5/686 , A61B2562/0219 , A61N1/36542
摘要： Systems and methods obtain information that allows detection of whether a patient suffers from congestion b y monitoring a response of the patient to a recumbent position of the patient's body. The patient may be monitored to determine a respiration pattern for a non-recumbent position such as standing and a respiration pattern for a recumbent position such as lying down. The two patterns may be compared, either by a processing device or a physician, to determine a difference in the two respiration patterns. Furthermore, the congestion may be inferred from detecting an amount of time that the patient spends in a recumbent position or from detecting the recumbent angle that the patient obtains, either of which is presumed to indicate whether a recumbent position presents discomfort to the patient due to the presence of congestion. The device includes a reclination sensor (202), a respiration sensor (208), a processor (206), a memory (212) and telemetry means (214).
摘要翻译：系统和方法获得信息，其允许检测患者是否遭受阻塞，以监测患者对患者身体的卧位的反应。可以监测患者以确定用于躺卧位置的无卧位的呼吸模式，例如躺卧和躺卧位置的呼吸模式。可以通过处理装置或医师来比较两种模式，以确定两种呼吸模式的差异。此外，可以通过检测患者在躺卧位置中花费的时间量或从检测患者获得的躺卧角度来推断拥塞，其中任何一个被推定为指示躺卧位置是否由于患者的不适而给患者带来不适拥堵的存在。该装置包括倾斜传感器（202），呼吸传感器（208），处理器（206），存储器（212）和遥测装置（214）。

8. 发明申请

WO2004030748A2 SYSTEM FOR CARDIAC PACING WITH VARIABLE SAFETY MARGIN 审中-公开
标题翻译：具有可变安全标志的护肤系统
公开(公告)号：WO2004030748A2
公开(公告)日：2004-04-15
申请号：PCT/US2003/028678
申请日：2003-09-12
申请人： CARDIAC PACEMAKERS, INC.
发明人： ZHU, Qingsheng
IPC分类号： A61N1/00
CPC分类号： A61N1/3712
摘要： A cardiac pacemaker in which a variable safety margin with respect to a capture threshold is employed in delivering pacing pulses. The safety margin of a pacing pulse is made to vary in accordance with the pattern of preceding intrinsic and paced beats. The pacing pulse energy is thereby maintained at a more optimum value with respect to the capture threshold.
摘要翻译：一种心脏起搏器，其中采用相对于捕获阈值的可变安全裕度用于输送起搏脉冲。使起搏脉冲的安全裕度根据前面的固有节奏和节奏节奏的模式而变化。因此起搏脉冲能量相对于捕获阈值保持在更优化的值。

9. 发明申请

WO2003041797A2 SYSTEM FOR DETERMINING CHANGES IN HEART FAILURE STATUS 审中-公开
标题翻译：确定心力衰竭状态变化的系统
公开(公告)号：WO2003041797A2
公开(公告)日：2003-05-22
申请号：PCT/US2002/036821
申请日：2002-11-15
申请人： CARDIAC PACEMAKERS, INC.
发明人： ZHU, Qingsheng , SPINELLI, Julio, C. , KENKNIGHT, Bruce, H. , WARREN, Jay, A.
IPC分类号： A61N1/37
CPC分类号： A61N1/3627 , A61N1/36585
摘要： A method for operating a cardiac rhythm management device in which a clinical state vector is computed as a combination of a plurality of parameters related to a patient's heart failure status and compared to a previously computed clinical state vector to determine a clinical trajectory indicative of changes in the patient's heart failure status. Such detected changes in status can be used both as a clinical tool to evaluate treatment and to automatically adjust the operation of the device.
摘要翻译：一种用于操作心律管理装置的方法，其中临床状态向量被计算为与患者的心力衰竭状态相关的多个参数的组合并且与先前计算的临床状态向量确定指示患者心力衰竭状态变化的临床轨迹。这种检测到的状态变化既可以用作评估治疗的临床工具，也可以自动调整设备的操作。

10. 发明申请

WO2003026740A1 EVOKED RESPONSE SENSING FOR ISCHEMIA DETECTION 审中-公开
标题翻译：用于ISCHEMIA检测的反应感测
公开(公告)号：WO2003026740A1
公开(公告)日：2003-04-03
申请号：PCT/US2002/030414
申请日：2002-09-25
申请人： CARDIAC PACEMAKERS, INC.
发明人： ZHU, Qingsheng
IPC分类号： A61N1/362
CPC分类号： A61N1/36507 , A61N1/3712
摘要： A cardiac pacemaker in which an electrogram is recorded from an evoked response sensing channel in order to detect changes indicative of cardiac ischemia. If such changes are detected, the maximum allowable pacing rate can be decreased for those pacing modes that allow the pacing rate to change with metabolic demand.
摘要翻译：一种心脏起搏器，其中从诱发的响应感测通道记录电描记图，以便检测指示心脏缺血的变化。如果检测到这种变化，那些起搏模式允许起搏速率随代谢需求而改变的最大允许起搏速率可以降低。

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