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1. 发明申请

WO2012002406A1 OPTICAL COHERENCE TOMOGRAPHY AND METHOD THEREOF 审中-公开
标题翻译：光学相干方法及其方法
公开(公告)号：WO2012002406A1
公开(公告)日：2012-01-05
申请号：PCT/JP2011/064853
申请日：2011-06-22
申请人： CANON KABUSHIKI KAISHA , UTSUNOMIYA, Norihiko , NAKAJIMA, Junko
发明人： UTSUNOMIYA, Norihiko , NAKAJIMA, Junko
IPC分类号： A61B3/12 , A61B3/113
CPC分类号： A61B3/12 , A61B3/102 , A61B3/14
摘要： The image sensing apparatus comprises a first scan unit for scanning light from an OCT light source and light from an SLO light source in a first direction of a test object, and a second scan unit for scanning the light from the OCT light source in a second direction different from the first direction of the test object. The image sensing apparatus acquires tomographic images of the test object along the first direction when the first scan unit scans the light from the OCT light source, and acquires cross-over images of the test object corresponding to the tomographic images when the first scan unit scans the light from the SLO light source.
摘要翻译：图像感测装置包括用于扫描来自OCT光源的光的第一扫描单元和来自测试对象的第一方向上的来自SLO光源的光，以及用于在第二扫描单元中扫描来自OCT光源的光的第二扫描单元方向与测试对象的第一个方向不同。当第一扫描单元扫描来自OCT光源的光时，图像感测装置获取沿着第一方向的测试对象的断层图像，并且当第一扫描单元扫描时获取与断层图像相对应的测试对象的交叉图像来自SLO光源的光。

2. 发明申请

WO2011093061A1 OPHTHALMOLOGIC IMAGING APPARATUS 审中-公开
标题翻译：眼科成像装置
公开(公告)号：WO2011093061A1
公开(公告)日：2011-08-04
申请号：PCT/JP2011/000387
申请日：2011-01-25
申请人： CANON KABUSHIKI KAISHA , UTSUNOMIYA, Norihiko , SUGITA, Mitsuro
发明人： UTSUNOMIYA, Norihiko , SUGITA, Mitsuro
IPC分类号： A61B3/12 , A61B3/113
CPC分类号： A61B3/1025 , A61B3/102
摘要： Provided is an ophthalmologic imaging apparatus suppressing the effect of a motion artifact caused by a movement of an eye to be inspected, comprising: a scanning unit for scanning, with first and second measuring beams, at least a part of an overlap area of scan areas thereof in an inspected eye, at different times, respectively; an image acquiring unit for acquiring first and second images of the inspected eye based on first and second return beams resulting from the first and second measuring beams being applied via the scanning unit and reflected by the inspected eye; an identification unit for identifying an image including a motion artifact from each of the first and second images; and an image forming unit for forming an image of the inspected eye based on the first and second images other than the images identified by the identification unit.
摘要翻译：本发明提供一种眼科成像装置，其抑制由被检查眼睛的运动引起的运动伪像的影响，包括：扫描单元，用于利用第一和第二测量光束扫描扫描区域的重叠区域的至少一部分分别在不同时间的检查眼中; 图像获取单元，用于基于由第一和第二测量光束产生的第一和第二返回光束，经由扫描单元施加并被被检查眼睛反射，获取被检查眼睛的第一和第二图像; 识别单元，用于从第一和第二图像中的每一个识别包括运动伪像的图像; 以及图像形成单元，用于基于除了由识别单元识别的图像之外的第一和第二图像来形成被检查眼睛的图像。

3. 发明申请

WO2010119750A1 OPTICAL TOMOGRAPHIC IMAGING APPARATUS AND CONTROL METHOD FOR THE SAME 审中-公开
标题翻译：光学成像装置及其控制方法
公开(公告)号：WO2010119750A1
公开(公告)日：2010-10-21
申请号：PCT/JP2010/054907
申请日：2010-03-16
申请人： CANON KABUSHIKI KAISHA , YOSHIDA, Hirofumi , UTSUNOMIYA, Norihiko
发明人： YOSHIDA, Hirofumi , UTSUNOMIYA, Norihiko
IPC分类号： A61B3/12 , G01N21/47
CPC分类号： A61B3/102 , G01N21/4795
摘要： There is provided an optical tomographic imaging apparatus for imaging a tomographic image capable of setting characteristics of an optical system to accommodate to different positions on an object. The apparatus using an OCT system, includes: a scanning device for scanning measuring beams, an irradiating device for irradiating a different irradiation area on the object with the measuring beams scanned by the scanning device, an adjusting device for adjusting an irradiation position on the object of the measuring beams irradiated by the irradiating device, and a detecting device for detecting each combined beam produced from light interference between each of the return beams and the reference beams, characterized in that: the detecting device includes spectroscopy devices and a sensor, and a spectral width of the combined beam acquired with the sensor through the spectroscopy devices is set at a different spectral width by the spectroscopy devices.
摘要翻译：提供了一种用于对能够设置光学系统的特性以适应物体上的不同位置的断层图像成像的光学层析成像装置。使用OCT系统的装置包括：用于扫描测量光束的扫描装置，用扫描装置扫描的测量光束照射物体上的不同照射区域的照射装置，用于调节对象上的照射位置的调节装置的检测装置，以及检测装置，用于检测由每个返回光束和参考光束之间的光干涉产生的每个组合光束，其特征在于：所述检测装置包括光谱装置和传感器，以及通过光谱装置用传感器获取的组合光束的光谱宽度被光谱装置设置在不同的光谱宽度。

4. 发明申请

WO2010150483A4 IMAGE PICKUP APPARATUS AND IMAGE PICKUP METHOD USING OPTICAL COHERENCE TOMOGRAPHY 审中-公开
公开(公告)号：WO2010150483A4
公开(公告)日：2010-12-29
申请号：PCT/JP2010/003977
申请日：2010-06-15
申请人： CANON KABUSHIKI KAISHA , SUEHIRA, Nobuhito , YAMADA, Kazuro , UTSUNOMIYA, Norihiko , NABA, Takashi , KUROSAKA, Ryoji , SUZUKI, Kei
发明人： SUEHIRA, Nobuhito , YAMADA, Kazuro , UTSUNOMIYA, Norihiko , NABA, Takashi , KUROSAKA, Ryoji , SUZUKI, Kei
IPC分类号： A61B3/12 , G01B9/02 , G01J3/02 , G01J3/45
摘要： The present invention relates to an apparatus having a simple configuration capable of correctly detecting malfunction of an OCT apparatus by detecting the states of a light source and a sensor. An image pickup apparatus includes a switching unit that switches between a first mode in which a combined light beam of a return light beam from a specimen and a reference light beam is detectable by a detecting unit and a second mode in which the reference light beam is detectable by the detecting unit. The image pickup apparatus is switchable to the first mode on the basis of an intensity of the reference light beam detected by the detecting unit in the second mode.

5. 发明申请

WO2010128626A1 OPTICAL COHERENCE TOMOGRAPHIC IMAGING APPARATUS 审中-公开
标题翻译：光学相干图像成像装置
公开(公告)号：WO2010128626A1
公开(公告)日：2010-11-11
申请号：PCT/JP2010/057105
申请日：2010-04-15
申请人： CANON KABUSHIKI KAISHA , MAKIHIRA, Tomoyuki , UTSUNOMIYA, Norihiko
发明人： MAKIHIRA, Tomoyuki , UTSUNOMIYA, Norihiko
IPC分类号： A61B3/12 , A61B5/00 , G01B9/02 , G01N21/47
CPC分类号： A61B3/102 , A61B5/0066 , A61B5/0073 , G01B9/02021 , G01B9/02027 , G01B9/02044 , G01B9/02068 , G01B9/02077 , G01B9/02083 , G01B9/02091 , G01B2290/35 , G01B2290/70 , G01N21/4795
摘要： Optical coherence tomographic imaging apparatus creating tomographic image of inspection object includes light splitting means for splitting light from light source into a single reference light and a single sample light, optical path length changing means for changing optical path length of the single reference light, reference light splitting means for splitting the single reference light whose optical path length is changed into a plurality of reference lights, sample light splitting means for splitting the single sample light into a plurality of sample lights, irradiation means for irradiating the inspection object by leading the plurality of sample lights thereto, interference signal forming means for combining returning lights of the plurality of the sample lights from the inspection object irradiated by the irradiation means with the plurality of reference lights passed through the reference-light path, and interference signal obtaining means for obtaining an interference signal from the interference signal forming means.
摘要翻译：产生检查对象的断层图像的光学相干断层图像摄影装置包括：将来自光源的光分为单个参考光和单个采样光的光分离装置，用于改变单个参考光的光程长度的光程长度改变装置，参考光将光路长度变化为多个基准光的单个基准光分离的分割装置，将单个采样光分割为多个采样光的采样分光装置，通过使多个参考光引导来照射检查对象的照射装置对来自被照射装置照射的检查对象物的多个样本光的返回光与通过基准光路的多个基准光进行合成的干涉信号形成单元，以及干涉信号取得单元，干扰信号来自干扰信号形成装置。

6. 发明申请

WO2010119913A1 OPTICAL TOMOGRAPHIC IMAGING APPARATUS AND CONTROL METHOD THEREFOR 审中-公开
标题翻译：光学成像装置及其控制方法
公开(公告)号：WO2010119913A1
公开(公告)日：2010-10-21
申请号：PCT/JP2010/056724
申请日：2010-04-08
申请人： CANON KABUSHIKI KAISHA , UTSUNOMIYA, Norihiko , MIYATA, Kazuhide
发明人： UTSUNOMIYA, Norihiko , MIYATA, Kazuhide
IPC分类号： G01B9/02 , A61B3/12 , G01N21/47
CPC分类号： G01B9/02068 , A61B3/102 , G01B9/02019 , G01B9/02027 , G01B9/02044 , G01B9/02077 , G01B9/02083 , G01B9/02091 , G01N21/4795
摘要： There are provided an optical tomographic imaging apparatus which detects an amount of movement of an object during imaging to reduce a deformation or a displacement in a depth direction in an acquired image. The apparatus using interference beams obtained by combining each return beam with each reference beam, the return beams being obtained by scanning the object with measuring beams, including: a unit adapted to scan the object with the measuring beams; a unit adapted to irradiate the object with the measuring beams such that regions of the object irradiated with each measuring beams are partially overlapped; a unit adapted to calculate a positional difference in a depth direction between obtained tomographic images of the overlapped parts of the regions; and a unit adapted to compute an amount of movement of the object based on the calculated positional difference in the depth direction.
摘要翻译：提供了一种光学层析成像设备，其在成像期间检测物体的移动量以减少获取的图像中的深度方向上的变形或位移。使用通过将每个返回光束与每个参考光束组合而获得的干涉光束的装置，返回光束通过用测量光束扫描对象而获得，包括：适于用测量光束扫描对象的单元; 适于用所述测量光束照射所述物体的单元，使得被每个测量光束照射的物体的部分部分地重叠; 适于计算所述区域的重叠部分的所获得的断层图像之间的深度方向上的位置差异的单元; 以及适于基于所计算的深度方向上的位置差来计算物体的移动量的单元。

7. 发明申请

WO2006030957A1 DEVICE AND METHOD FOR ACQUIRING INFORMATION ON OBJECTIVE SUBSTANCE TO BE DETECTED BY DETECTING A CHANGE OF WAVELENGHT CHARACTERISTICS ON THE OPTICAL TRANSMITTANCE 审中-公开
标题翻译：通过检测光学特性波长特性变化来检测目标物质信息的装置和方法
公开(公告)号：WO2006030957A1
公开(公告)日：2006-03-23
申请号：PCT/JP2005/017326
申请日：2005-09-14
申请人： CANON KABUSHIKI KAISHA , UTSUNOMIYA, Norihiko , SUGITA, Mitsuro , NISHIUMA, Satoru , YONEHARA, Takao
发明人： UTSUNOMIYA, Norihiko , SUGITA, Mitsuro , NISHIUMA, Satoru , YONEHARA, Takao
IPC分类号： G01N21/55
CPC分类号： G01N21/554 , G01N21/648 , G01N2021/258 , G01N2201/0635 , G01N2201/0636
摘要： An information-acquiring device for acquiring information on an objective substance to be detected, which is provided with a sensing element (104) that has a surface capable of fixing the objective substance to be detected thereon, and makes applied light change its wavelength characteristics in response to the fixed state of the objective substance to be detected onto the surface, a light source (102), and light-receiving means (103) for receiving light (111, 112) emitted from the light source (102) through the sensing element (104), has the light-receiving means (103) and the light source (102) arranged on the same substrate (101) so that the light which has been emitted from the light source (102) and has been transmitted through the sensing element (104) can be led to the light-receiving means (103), and has means (107) for varying the wavelength regions of each light incident on each of a plurality of the light-receiving means (103) installed in an optical path from the light source (102) to the light-receiving means (103).
摘要翻译：一种用于获取关于待检测目标物质的信息的信息获取装置，该信息获取装置设置有具有能够固定待检测目标物质的表面的感测元件（104），并使施加的光改变其波长特性响应待检测到的目标物质的固定状态，光源（102）和光接收装置（103），用于接收从光源（102）发射的光（111,112）通过感测元件（104）具有布置在相同基板（101）上的光接收装置（103）和光源（102），使得已经从光源（102）发射并已经透过感测元件（104）可以被引导到光接收装置（103），并且具有用于改变入射到安装在光接收装置（103）中的多个光接收装置（103）中的每一个的每个光的波长区域的装置（107）光路从轻酸 ce（102）连接到光接收装置（103）。

8. 发明申请

WO2005085806A1 RECOGNITION CHIP FOR TARGET SUBSTANCE, AND DETECTION METHOD AND DEVICE FOR THE SAME 审中-公开
标题翻译：目标物质的识别芯片及其相关的检测方法和装置
公开(公告)号：WO2005085806A1
公开(公告)日：2005-09-15
申请号：PCT/JP2005/004029
申请日：2005-03-02
申请人： CANON KABUSHIKI KAISHA , YAMAMICHI, Junta , OGAWA, Miki , HANDA, Yoichiro , IMAMURA, Takeshi , UTSUNOMIYA, Norihiko , NISHIUMA, Satoru
发明人： YAMAMICHI, Junta , OGAWA, Miki , HANDA, Yoichiro , IMAMURA, Takeshi , UTSUNOMIYA, Norihiko , NISHIUMA, Satoru
IPC分类号： G01N21/05
CPC分类号： G01N21/05 , G01N21/554 , G01N21/645 , G01N21/66 , G01N2021/0346
摘要： A detection device comprising a substrate (103) comprising a plurality of objects (105) of which properties are changed due to the contact with a target substance, means for bringing the target substance into contact with the objects, and means (101, 107) for detecting a change in properties of the objects caused when the target substance is brought into contact with the objects, based on light output (106) when the objects are irradiated with light (102), wherein the plurality of the objects are located in the direction in which the light for irradiation travels, and the detecting means is means for detecting the change in the properties based on the summation of light output from the plurality of the objects upon irradiation with light.
摘要翻译：一种检测装置，包括：基板（103），包括由于与目标物质的接触而改变其特性的多个物体（105），使目标物质与物体接触的装置，以及装置（101,107）用于当物体被照射光（102）时，基于光输出（106）检测当目标物质与物体接触时引起的物体的性质变化，其中多个物体位于照射光的行进方向，检测装置是用于根据在照射光时从多个物体输出的光的总和来检测特性变化的装置。

9. 发明公开

EP2382914A1 Ophthalmologic apparatus and ophthalmologic observation method 审中-公开
标题翻译：眼科学和眼科学Beobachtungsverfahren
公开(公告)号：EP2382914A1
公开(公告)日：2011-11-02
申请号：EP11163016.6
申请日：2011-04-19
申请人： Canon Kabushiki Kaisha
发明人： NAKAJIMA, Junko , UTSUNOMIYA, Norihiko
IPC分类号： A61B3/113 , A61B3/12 , G06T7/00 , A61B3/10
CPC分类号： A61B3/102
摘要： To accurately detect a movement of an object based on an image distorted by the movement of an eye to be inspected, which is acquired by a scanning imaging system, provided is an ophthalmologic apparatus including: an extraction means for extracting a plurality of characteristic images from a first fundus image of the eye to be inspected; a fundus image acquisition means for acquiring a second fundus image of the eye to be inspected during a period different from a period during which the first fundus image is acquired; and a calculation means for calculating at least a rotation of movements of the eye to be inspected based on the plurality of characteristic images and the second fundus image.
摘要翻译：为了准确地检测基于由扫描成像系统获取的被检眼的运动而失真的图像的物体的移动，是一种眼科装置，包括：提取装置，用于从多个特征图像中提取多个特征图像眼睛的第一眼底像被检查; 眼底图像获取装置，用于在与获取第一眼底图像的时段不同的时间段内获取要检查的眼睛的第二眼底图像; 以及计算装置，用于基于所述多个特征图像和所述第二眼底图像计算至少要检查的眼睛的运动的旋转。

10. 发明公开

EP4357788A1 METHOD FOR ANALYZING SPECIMEN, AND SPECIMEN ANALYZING DEVICE 审中-实审
公开(公告)号：EP4357788A1
公开(公告)日：2024-04-24
申请号：EP22842067.5
申请日：2022-07-11
申请人： CANON KABUSHIKI KAISHA , Canon Medical Systems Corporation
发明人： FURUKAWA, Yukio , KII, Hiroshi , UTSUNOMIYA, Norihiko , OZAKI, Masahiro , SATAKE, Hiroto
IPC分类号： G01N37/00 , G01N35/10 , G01N33/483 , G01N33/50 , G01N33/543 , G01N33/68 , G01N21/03 , G01N21/11 , G01N21/64
CPC分类号： G01N33/483 , G01N33/50 , G01N35/10 , G01N37/00 , G01N21/64 , G01N21/11 , G01N33/68 , G01N33/543 , G01N21/03
摘要： Analysis using an array plate typically requires a drying step. However, the drying step interrupts a series of operations. Further, non-uniform drying of the array plate has been a factor of reducing repeatability. The present invention proposes a method of acquiring optical information of a plurality of spots under a state in which the plurality of spots are in contact with an observation liquid.

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