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1. 发明申请

WO2020058668A1 LIGHT-EMITTING MARKER PARTICLES 审中-公开
公开(公告)号：WO2020058668A1
公开(公告)日：2020-03-26
申请号：PCT/GB2019/052511
申请日：2019-09-09
申请人： CAMBRIDGE DISPLAY TECHNOLOGY LIMITED , SUMITOMO CHEMICAL COMPANY LIMITED
发明人： BEHRENDT, Jonathan , O'SULLIVAN, Melanie
IPC分类号： C09K11/02 , C09K11/06 , G01N33/533
摘要： A light-emitting marker particle having a light-emitting particle core containing a light- emitting material and first and second surface groups bound to the light-emitting particle core. The first surface group contains a polar group and is an inert group which does not bind to a biomolecule. The second surface group contains a biomolecule binding group.

2. 发明申请

WO2020058123A1 LIGHT-EMITTING PARTICLE 审中-公开
公开(公告)号：WO2020058123A1
公开(公告)日：2020-03-26
申请号：PCT/EP2019/074502
申请日：2019-09-13
申请人： CAMBRIDGE DISPLAY TECHNOLOGY LIMITED , SUMITOMO CHEMICAL COMPANY LIMITED
发明人： BEHRENDT, Jonathan , ISLAM, Nazrul , KAMTEKAR, Kiran
IPC分类号： C09K11/06 , H01L51/00 , C09K11/02
摘要： A particle having an inorganic matrix material and a light-emitting polymer wherein the light-emitting polymer has a light-emitting group and a host repeat unit, wherein a bandgap of the host repeat unit is greater than that of the light-emitting group, wherein the light-emitting group makes up no more than 10 mol % of the groups of the light- emitting polymer and wherein the polymer has a solubility in water or a Ci-s alcohol at 20 °C of at least 0.1 mg/mL.

3. 发明申请

WO2020058440A1 LIGHT-EMITTING PARTICLE 审中-公开
公开(公告)号：WO2020058440A1
公开(公告)日：2020-03-26
申请号：PCT/EP2019/075235
申请日：2019-09-19
申请人： CAMBRIDGE DISPLAY TECHNOLOGY LIMITED , SUMITOMO CHEMICAL COMPANY LIMITED
发明人： BEHRENDT, Jonathan , KAMTEKAR, Kiran
IPC分类号： C09K11/02 , C09K11/06 , G01N21/64
摘要： A particle comprising an inorganic matrix material; a first light-emitting material; and a second light-emitting material, wherein the first light-emitting material is a light- emitting polymer. The first and second light-emitting materials may have opposing ionic charges. The first light-emitting material may transfer excitation energy to the second light-emitting material. A biomolecule binding group may be bound to the particle.

4. 发明申请

WO2018029014A1 LIGHT FILTER AND SENSOR 审中-公开
标题翻译：滤光片和传感器
公开(公告)号：WO2018029014A1
公开(公告)日：2018-02-15
申请号：PCT/EP2017/069161
申请日：2017-07-28
申请人： CAMBRIDGE DISPLAY TECHNOLOGY LIMITED , SUMITOMO CHEMICAL COMPANY LIMITED
发明人： BURROUGHES, Jeremy , LEE, Andrew , BEHRENDT, Jonathan
IPC分类号： G01N21/64 , G02B5/22
摘要： A sensor comprising a light source (103); a photodetector (105); a sample receptacle such as a microfluidic device (101) between the light source and the photodetector; and one or both of a first light filter (107) and a second light filter (109) wherein the first light filter is provided between the sample receptacle and the photodetector and the second light filter is provided between the sample receptacle and the light source. The first light filter may comprise tartrazine. The second light filter may comprise Coomassie violet R200, Victoria Blue B or acid fuchsin. In use, light hν1 emitted from the light source is absorbed by a luminescent indicator in the sample receptacle which then emits light hν2 detected by the photodetector.
摘要翻译：一种包括光源（103）的传感器; 一个光电探测器（105）; 在光源和光电检测器之间的样品容器，例如微流体装置（101）以及第一滤光器（107）和第二滤光器（109）中的一个或两个，其中第一滤光器设置在样品容器和光电检测器之间，并且第二滤光器设置在样品容器和光源之间。第一滤光器可以包含酒石黄。第二滤光器可以包括考马斯紫R200，维多利亚蓝B或酸性品红。在使用中，从光源发出的光hν1被样品容器中的发光指示器吸收，然后发出由光电检测器检测到的光hν2。

5. 发明申请

WO2018060722A1 COMPOSITE PARTICLE 审中-公开
标题翻译：复合粒子
公开(公告)号：WO2018060722A1
公开(公告)日：2018-04-05
申请号：PCT/GB2017/052924
申请日：2017-09-29
申请人： SUMITOMO CHEMICAL COMPANY LIMITED , CAMBRIDGE DISPLAY TECHNOLOGY LIMITED
发明人： BEHRENDT, Jonathan , BOURCET, Florence
IPC分类号： C09K11/06 , C09K11/02 , B01J13/00 , B82Y15/00 , B82Y30/00 , B82Y40/00 , C01B33/14 , C08G61/00
摘要： A composite comprising silica and a light- emitting polymer comprising a backbone and polar groups pendant from the backbone.
摘要翻译：包含二氧化硅和发光聚合物的复合物，所述发光聚合物包含骨架和从主链侧接的极性基团。

6. 发明申请

WO2017216525A1 METHOD, COMPOSITION AND SENSOR FOR ANALYTE DETECTION 审中-公开
标题翻译：分析检测的方法，组合物和传感器
公开(公告)号：WO2017216525A1
公开(公告)日：2017-12-21
申请号：PCT/GB2017/051689
申请日：2017-06-09
申请人： CAMBRIDGE DISPLAY TECHNOLOGY LIMITED , SUMITOMO CHEMICAL COMPANY LIMITED
发明人： BEHRENDT, Jonathan
IPC分类号： C12Q1/54 , C12Q1/60 , G01N33/52 , G01N33/66
CPC分类号： G01N33/66 , C12Q1/26 , C12Q1/54 , C12Q1/60 , C12Q2521/50 , C12Y101/03004 , C12Y101/03006 , G01N31/228 , G01N33/52 , G01N33/526
摘要： A method of testing a liquid sample for the presence of an analyte, the method comprising the steps of: forming a mixture by contacting the sample with a composition comprising an oxidase for formation of hydrogen peroxide from the analyte, a fluorescent indicator precursor capable of forming a fluorescent indicator in the presence of an oxygen radical and an iron compound wherein the iron compound is dissolved in the mixture; irradiating the mixture; and measuring fluorescence from the fluorescent indicator. The method may be carried out using a device in which the mixture in a channel or chamber (101) of a microfluidic device is irradiated by light from light source (103) and emission from the fluorescent indicator is detected by photodetector (105).
摘要翻译：测试液体样品中分析物存在的方法，所述方法包括以下步骤：通过使样品与包含用于从分析物形成过氧化氢的氧化酶的组合物接触来形成混合物，能够在氧自由基和铁化合物存在下形成荧光指示剂的荧光指示剂前体，其中铁化合物溶解在混合物中; 照射混合物; 并测量荧光指示剂的荧光。该方法可以使用其中微流体装置的通道或腔室（101）中的混合物被来自光源（103）的光照射并且来自荧光指示器的发射被光检测器（105）检测的装置来执行。 / p>

7. 发明申请

WO2017220346A1 METHOD, COMPOSITION AND SENSOR FOR TESTING A SAMPLE FOR THE PRESENCE OF NITRATE OR NITRITE 审中-公开
标题翻译：用于测试存在硝酸盐或亚硝酸盐的样品的方法，组合物和传感器
公开(公告)号：WO2017220346A1
公开(公告)日：2017-12-28
申请号：PCT/EP2017/064123
申请日：2017-06-09
申请人： CAMBRIDGE DISPLAY TECHNOLOGY LIMITED , SUMITOMO CHEMICAL COMPANY LIMITED
发明人： BEHRENDT, Jonathan
IPC分类号： G01N21/64 , B01L3/00 , C12Q1/26 , G01N21/77
CPC分类号： G01N21/6428 , B01L3/5027 , B01L3/502715 , B01L2300/0636 , C12Q1/26 , C12Y101/0304 , C12Y107/99004 , G01N21/77 , G01N33/182 , G01N2021/1765 , G01N2021/6439 , G01N2021/7786 , G01N2201/0628
摘要： A method of testing a sample for the presence of nitrate or nitrite, the method comprising the steps of: forming a mixture by contacting the sample with a composition comprising hydrogen peroxide or a hydrogen peroxide precursor and a fluorescent indicator precursor capable of forming a fluorescent indicator in the presence of peroxynitrite; irradiating the mixture; and measuring fluorescence from the fluorescent indicator. The method may be carried out using a device in which the mixture in a channel or chamber 101 of a microfluidic device is irradiated by light from light source 103 and emission from the fluorescent indicator is detected by photodetector 105.
摘要翻译：一种测试样品中是否存在硝酸盐或亚硝酸盐的方法，所述方法包括以下步骤：通过使所述样品与包含过氧化氢或过氧化氢前体和荧光剂的组合物接触来形成混合物在过氧亚硝酸盐存在下能够形成荧光指示剂的指示剂前体; 照射混合物; 并测量荧光指示剂的荧光。该方法可以使用如下装置来执行，其中微流体装置的通道或腔室101中的混合物被来自光源103的光照射，并且来自荧光指示器的发射被光电检测器105检测到。

8. 发明公开

EP3535565A1 LIGHT FILTER AND SENSOR 审中-公开
公开(公告)号：EP3535565A1
公开(公告)日：2019-09-11
申请号：EP17751053.4
申请日：2017-07-28
申请人： Cambridge Display Technology Limited , Sumitomo Chemical Company Limited
发明人： BURROUGHES, Jeremy , LEE, Andrew , BEHRENDT, Jonathan
IPC分类号： G01N21/64 , G02B5/22

9. 发明公开

EP3469096A1 METHOD, COMPOSITION AND SENSOR FOR ANALYTE DETECTION 审中-公开
公开(公告)号：EP3469096A1
公开(公告)日：2019-04-17
申请号：EP17730248.6
申请日：2017-06-09
申请人： Cambridge Display Technology Limited , Sumitomo Chemical Company Limited
发明人： BEHRENDT, Jonathan
IPC分类号： C12Q1/54 , C12Q1/60 , G01N33/52 , G01N33/66

10. 发明申请

WO2021069902A1 LIGHT-EMITTING COMPOSITION 审中-公开
公开(公告)号：WO2021069902A1
公开(公告)日：2021-04-15
申请号：PCT/GB2020/052497
申请日：2020-10-08
申请人： SUMITOMO CHEMICAL CO., LTD , CAMBRIDGE DISPLAY TECHNOLOGY LIMITED
发明人： BEHRENDT, Jonathan , KAMTEKAR, Kiran , ISLAM, Nazrul
IPC分类号： C09K11/06 , H01L51/00
摘要： A light-emitting composition containing first and second light-emitting markers. The first light-emitting marker comprises a first light-emitting material and a first binding group configured to bind to a first target analyte. The second light-emitting marker comprises a second light-emitting material which is different from the first light- emitting material and a second binding group which is different from the first binding group and which is configured to bind to a second target analyte. A luminescent lifetime of the first light-emitting material is shorter than a luminescent lifetime of the second light-emitting material. The difference in lifetimes of the first and second light- emitting materials may be used to distinguish between the first and second target analytes in a sample, e.g. by time-gated flow cytometry.

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