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1. 发明申请

WO2010022069A3 DRUG INFUSION SYSTEM WITH REUSABLE AND DISPOSABLE COMPONENTS 审中-公开
标题翻译：具有可重复使用和可重复使用的组分的药物输注系统
公开(公告)号：WO2010022069A3
公开(公告)日：2010-05-27
申请号：PCT/US2009054186
申请日：2009-08-18
申请人： CALIBRA MEDICAL INC , MCKENZIE JOHN , CROSS BRETT , MARSOT TRAVIS
发明人： MCKENZIE JOHN , CROSS BRETT , MARSOT TRAVIS
IPC分类号： A61M5/142 , A61M5/158
CPC分类号： A61M5/14248 , A61M5/1424 , A61M5/1452 , A61M5/1454 , A61M2005/14252 , A61M2005/14268
摘要： The application discloses a drug infusion system comprising a base and a drug dispenser. The base is configured to receive a cannula that delivers a drug to beneath a wearer's skin. The base is attachable to the skin of the wearer. The reusable drug dispenser is removably attachable to the base and has a pump unit configured to establish fluid communication between a removably attachable drug reservoir and the cannula. The pump unit pumps the drug to the wearer upon activation by the wearer. The pump unit may have an inlet to contact the drug within the reservoir, which may be a needle. The pump unit may also have a receiving unit to receive the reservoir. Such a receiving unit may be a tubular for a cylindrical reservoir, or may have a cavity or an encasing unit to hold the reservoir.
摘要翻译：该申请公开了一种药物输注系统，其包括基座和药物分配器。基座构造成接收将药物输送到佩戴者皮肤下的套管。基座可连接到佩戴者的皮肤上。可重复使用的药物分配器可拆卸地连接到基座上并具有泵单元，该泵单元被构造成建立可拆卸地连接的药物储存器和套管之间的流体连通。泵单元在佩戴者激活时将药物泵送到佩戴者。泵单元可以具有入口以接触储存器内的药物，该储存器可以是针。泵单元还可以具有接收单元以接收储存器。这种接收单元可以是用于圆柱形储存器的管状件，或者可以具有用于保持储存器的空腔或包装单元。

2. 发明申请

WO2009158651A3 DISPOSABLE INFUSION DEVICE WITH PRIME INDICATOR 审中-公开
标题翻译：具有主要指示剂的可移植输液装置
公开(公告)号：WO2009158651A3
公开(公告)日：2010-03-11
申请号：PCT/US2009048917
申请日：2009-06-26
申请人： CALIBRA MEDICAL INC , CROSS BRETT , MARSOT TRAVIS
发明人： CROSS BRETT , MARSOT TRAVIS
IPC分类号： A61M5/142 , A61M5/145 , A61M37/00
CPC分类号： A61M5/1424 , A61M5/14216 , A61M5/14248 , A61M2005/1402 , A61M2005/1585 , A61M2205/273
摘要： A disposable wearable infusion device comprises a base that is arranged to adhere to the surface of a patient, a source arranged to provide a liquid medicament to be delivered to a patient, an outlet through which the medicament is delivered to the patient, a pump that pumps the medicament, and a conduit that conducts the pumped medicament to the outlet. The device further comprises a prime indicator that provides a visible indication that the conduit is substantially full with medicament from the reservoir to the outlet.
摘要翻译：一次性佩戴式输注装置包括布置成粘附到患者表面的基部，源被设置成提供待输送到患者的液体药物，将药物输送到患者的出口，泵泵送药物，以及将泵送的药物导引到出口的导管。该装置还包括主指示器，其提供导管基本上充满药剂的可见指示，该储存器至出口。

3. 发明申请

WO2011060364A3 WEARABLE INFUSION DEVICE AND SYSTEM 审中-公开
标题翻译：可口的输液装置和系统
公开(公告)号：WO2011060364A3
公开(公告)日：2011-10-13
申请号：PCT/US2010056715
申请日：2010-11-15
申请人： CALIBRA MEDICAL INC , CARTER BRETT J , MCKENZIE JOHN , ADAMS JOHN M , CROSS BRETT , MARSOT TRAVIS
发明人： CARTER BRETT J , MCKENZIE JOHN , ADAMS JOHN M , CROSS BRETT , MARSOT TRAVIS
IPC分类号： A61M5/14 , A61M5/162 , A61M37/00 , A61M39/06
CPC分类号： A61M5/158 , A61M5/14244 , A61M5/14248 , A61M5/162 , A61M5/1626 , A61M5/16831 , A61M39/26 , A61M2005/14252 , A61M2005/1585 , A61M2005/1588
摘要： Disclosed is a drug infusion system comprising a drug infusion device having a reservoir, a window for viewing the contents of the reservoir, a cannula arranged to be deployed beneath the skin of a patient, and an actuator configured to be manually actuated to drive a medicament from the reservoir to the cannula. The system also has a cannula cover and a needle handle that holds a needle for insertion into the patient. The cannula cover and needle handle are detachably attached to the drug infusion device, and each is attachable to the other. The device further comprises a septum and a septum pincher to seal the device. The device also comprises a pumping mechanism, part of which are a last-dose lock-out mechanism and an occlusion detection mechanism, both of which operate on the same actuator.
摘要翻译：公开了一种药物输注系统，其包括具有储存器的药物输注装置，用于观察储存器的内容物的窗口，布置成展开在患者皮肤下方的套管以及构造成手动致动以驱动药物的致动器从储存器到套管。该系统还具有套管盖和针柄，其保持用于插入患者体内的针头。套管盖和针柄可拆卸地附接到药物输注装置，并且每个可附接到另一个。该装置还包括隔膜和隔膜夹子以密封该装置。该装置还包括泵送机构，其一部分是最后剂量锁定机构和遮挡检测机构，两者都在相同的致动器上操作。

4. 发明申请

WO2009158654A3 DISPOSABLE INFUSION DEVICE WITH CANNULA PORT COVER 审中-公开
标题翻译：具有肛门端盖的不可渗透的输液装置
公开(公告)号：WO2009158654A3
公开(公告)日：2010-04-08
申请号：PCT/US2009048924
申请日：2009-06-26
申请人： CALIBRA MEDICAL INC , CROSS BRETT , MARSOT TRAVIS , CARTER BRETT J
发明人： CROSS BRETT , MARSOT TRAVIS , CARTER BRETT J
IPC分类号： A61M5/142 , A61M5/158
CPC分类号： A61M5/1424 , A61M5/14216 , A61M5/14248 , A61M2005/1402 , A61M2005/1585 , A61M2205/273
摘要： A disposable wearable infusion device comprises a body arranged to be adhered to a patient's skin and to receive a cannula to extend from the infusion device to beneath the patient's skin, a reservoir for holding a liquid medicament to be infused into the patient, and a pump that displaces a volume of the liquid medicament from the reservoir to the cannula for delivery to the patient. The body has a port aligned with the cannula that permits the cannula to assume a deployed position to extend from the infusion device to beneath the patient's skin. The device further comprises a cover that blocks the port to preclude direct access to the cannula through the port after deployment.
摘要翻译：一次性佩戴式输注装置包括被布置成粘附到患者皮肤并且接收套管以从输液装置延伸到患者皮肤下方的主体，用于保持液体药剂注入到患者体内的储存器，以及泵其将一定体积的液体药物从储存器移位到套管以递送至患者。主体具有与插管对准的端口，其允许插管呈现展开位置，以从输注装置延伸到患者皮肤下方。该装置还包括盖子，其阻挡端口以排除部署后通过端口直接进入套管。

5. 发明申请

WO2010022069A2 DRUG INFUSION SYSTEM WITH REUSABLE AND DISPOSABLE COMPONENTS 审中-公开
公开(公告)号：WO2010022069A2
公开(公告)日：2010-02-25
申请号：PCT/US2009054186
申请日：2009-08-18
申请人： CALIBRA MEDICAL INC , MCKENZIE JOHN , CROSS BRETT , MARSOT TRAVIS
发明人： MCKENZIE JOHN , CROSS BRETT , MARSOT TRAVIS
IPC分类号： A61M5/142 , A61M5/158
CPC分类号： A61M5/14248 , A61M5/1424 , A61M5/1452 , A61M5/1454 , A61M2005/14252 , A61M2005/14268
摘要： The application discloses a drug infusion system comprising a base and a drug dispenser. The base is configured to receive a cannula that delivers a drug to beneath a wearer's skin. The base is attachable to the skin of the wearer. The reusable drug dispenser is removably attachable to the base and has a pump unit configured to establish fluid communication between a removably attachable drug reservoir and the cannula. The pump unit pumps the drug to the wearer upon activation by the wearer. The pump unit may have an inlet to contact the drug within the reservoir, which may be a needle. The pump unit may also have a receiving unit to receive the reservoir. Such a receiving unit may be a tubular for a cylindrical reservoir, or may have a cavity or an encasing unit to hold the reservoir.

6. 发明申请

WO2010062675A3 DOSAGE SENSING UNIT WITH TACTILE FEEDBACK 审中-公开
标题翻译：剂量感应单位与触觉反馈
公开(公告)号：WO2010062675A3
公开(公告)日：2010-10-14
申请号：PCT/US2009062731
申请日：2009-10-30
申请人： CALIBRA MEDICAL INC , KARRATT JOSEPH M , CROSS BRETT
发明人： KARRATT JOSEPH M , CROSS BRETT
IPC分类号： A61M5/14 , A61M5/172 , A61M37/00
CPC分类号： A61M5/14248 , A61M5/1424 , A61M5/16831 , A61M5/16881 , A61M2205/3317 , A61M2205/3331 , A61M2205/502 , A61M2205/52 , A61M2205/582 , A61M2205/583 , G08B6/00
摘要： A drug infusion assembly comprises a drug delivery device arranged to adhere to a patient's skin and includes a reservoir that holds the drug, a cannula that delivers the drug to the patient, and a pump that causes the drug to flow to the cannula. The assembly further includes a monitor device for providing information about the operation of a drug delivery device. The monitor device includes a housing arranged to be attached to and detached from the drug delivery device, a sensor that senses the operation of the drug delivery device and generates an activation signal, a clock mechanism that generates a time signal, a memory that receives and stores the activation signal and the time signal and creates an information packet coordinating the time signal and the activation signal, an interrogator that interrogates the memory such that the memory generates a memory signal in response thereto, and a responder that receives the memory signal and generates a response.
摘要翻译：药物注入组件包括布置成粘附到患者皮肤的药物递送装置，并且包括容纳药物的储存器，将药物递送给患者的套管以及使药物流动到套管的泵。该组件还包括用于提供关于药物输送装置的操作的信息的监视器装置。监视器装置包括布置成与药物输送装置连接和分离的壳体，感测药物输送装置的操作并生成激活信号的传感器，生成时间信号的时钟机构，接收和存储激活信号和时间信号并创建协调时间信号和激活信号的信息分组，询问存储器使得存储器响应于此产生存储信号的询问器，以及接收存储信号并产生一个回应。

7. 发明申请

WO2009045781A3 DISPOSABLE INFUSION DEVICE WITH MEDICAMENT LEVEL INDICATOR 审中-公开
标题翻译：具有药物水平指示器的一次性输液装置
公开(公告)号：WO2009045781A3
公开(公告)日：2009-06-25
申请号：PCT/US2008077327
申请日：2008-09-23
申请人： CALIBRA MEDICAL INC , CARTER BRETT J , CROSS BRETT
发明人： CARTER BRETT J , CROSS BRETT
IPC分类号： A61M5/142 , A61M37/00
CPC分类号： A61M5/1424 , A61M5/14248 , A61M5/1684 , A61M2039/009
摘要： A wearable infusion device comprises a reservoir, an outlet port, and a pump. The device further comprises a medicament level indicator including a non-elastic, non-compressible, elongated web fixed at one end with respect to the reservoir. The web is arranged to move with linear movement as the reservoir is filled and emptied.
摘要翻译：可佩戴输注装置包括储存器，出口端口和泵。该装置还包括药物液面指示器，该药物液面指示器包括相对于储存器固定在一端的非弹性的，不可压缩的细长网状物。随着容器被填充并排空，网布置成随着线性移动而移动。

8. 发明申请

WO2008143809A2 INFUSION ASSEMBLY 审中-公开
标题翻译：输注组合
公开(公告)号：WO2008143809A2
公开(公告)日：2008-11-27
申请号：PCT/US2008006004
申请日：2008-05-09
申请人： CALIBRA MEDICAL INC , CROSS BRETT , CARTER BRETT J , DALE NATHAN
发明人： CROSS BRETT , CARTER BRETT J , DALE NATHAN
IPC分类号： A61M5/158 , A61M5/20
CPC分类号： A61M5/158 , A61M5/1413 , A61M5/14248 , A61M2005/1426 , A61M2005/14268 , A61M2005/1585 , A61M2005/1587
摘要： An infusion assembly comprises a cannula subassembly and a source subassembly. The cannula subassembly includes a substantially planar base, a cannula projecting from the base so as to be beneath the patient's skin when the subassembly is deployed, and a generally cylindrical docking structure having a center axis substantially perpendicular to the base. A liquid medicament is dispensed from the cannula. The source subassembly is arranged to dock with the docking structure and includes a supply of liquid medicament that couples to the cannula upon the source subassembly docking with the cannula subassembly. The source subassembly also includes a primer that automatically primes the insulin fluid path to the cannula tip when the subassemblies are joined.
摘要翻译：输液组件包括套管子组件和源子组件。插管子组件包括基本上平面的基座，当组件展开时从基座突出以便在患者皮肤下方突出的套管以及具有基本上垂直于底座的中心轴的大致圆柱形的对接结构。从套管分配液体药物。源子组件布置成与对接结构对接并且包括在源组件对接与插管子组件时耦合到插管的液体药物供应。源子组件还包括当组件接合时自动将胰岛素流体路径引导到套管尖端的底漆。

9. 发明申请

WO2009045777A3 A WEARABLE INFUSION DEVICE 审中-公开
标题翻译：一种可穿戴式输液装置
公开(公告)号：WO2009045777A3
公开(公告)日：2009-07-16
申请号：PCT/US2008077317
申请日：2008-09-23
申请人： CALIBRA MEDICAL INC , CROSS BRETT , CARTER BRETT J , ADAMS JOHN M , MCKENZIE JOHN , SAUL TOM A
发明人： CROSS BRETT , CARTER BRETT J , ADAMS JOHN M , MCKENZIE JOHN , SAUL TOM A
IPC分类号： A61M5/142 , A61M37/00
CPC分类号： A61M5/14248 , A61M2005/1405
摘要： A wearable infusion device comprises a component that causes a piston to move an incremental distance to cause the device to dispense a dose of medicament from a reservoir.
摘要翻译：可佩戴输注装置包括使活塞移动增量距离以使装置从储存器分配一剂药物的部件。

10. 发明申请

WO2009045779A3 DISPOSABLE INFUSION DEVICE WITH REUSE LOCK-OUT 审中-公开
标题翻译：具有重新锁定功能的可重复输注设备
公开(公告)号：WO2009045779A3
公开(公告)日：2009-06-04
申请号：PCT/US2008077319
申请日：2008-09-23
申请人： CALIBRA MEDICAL INC , CARTER BRETT J , ADAMS JOHN M , CROSS BRETT
发明人： CARTER BRETT J , ADAMS JOHN M , CROSS BRETT
IPC分类号： A61M5/142 , A61M37/00
CPC分类号： A61M5/1424 , A61M5/14248 , A61M5/1684 , A61M2039/009
摘要： A wearable infusion device comprises a reservoir that holds a liquid medicament, an outlet port that delivers the liquid medicament to a patient, a pump that displaces a volume of the liquid medicament to the outlet port when actuated, and a control that actuates the pump. A lock-out disables the device when a predefined amount of medicament has been delivered to the outlet.
摘要翻译：一种可佩戴的输注装置包括容纳液体药物的储存器，将液体药物递送到患者的出口端口;当被致动时将液体药物的体积移动到出口端口的泵以及致动泵的控制器。当预定量的药物已经被输送到出口时，锁定将禁用该装置。

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