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1. 发明申请

US20140259212A1 Process for the Production of Fine Chemicals 审中-公开
标题翻译：精细化工生产工艺
公开(公告)号：US20140259212A1
公开(公告)日：2014-09-11
申请号：US13510783
申请日：2010-11-18
申请人： Gunnar Plesch , Astrid Blau , Michael Manfred Herold , Beate Kamlage , Birgit Wendel , Piotr Puzio , Stefan Henkes , Volker Haake , Wim Van Camp , Holger Fahnenstich , Bryan McKersie , Wesley Bruce , Nicole Christiansen
发明人： Gunnar Plesch , Astrid Blau , Michael Manfred Herold , Beate Kamlage , Birgit Wendel , Piotr Puzio , Stefan Henkes , Volker Haake , Wim Van Camp , Holger Fahnenstich , Bryan McKersie , Wesley Bruce , Nicole Christiansen
IPC分类号： C12P1/00 , C12N15/82
CPC分类号： C12N15/8261 , C12N15/8243 , C12P1/00 , Y02A40/146
摘要： The present invention relates to a process for the production of a fine chemical in a non-human organism, like a microorganism, a plant cell, a plant, a plant tissue or in one or more parts thereof. The invention furthermore relates to nucleic acid molecules, polypeptides, nucleic acid constructs, expression cassettes, vectors, antibodies, host cells, plant tissue, propagation material, harvested material, plants, microorganisms as well as agricultural compositions and to their use.
摘要翻译：本发明涉及在非人体生物体如微生物，植物细胞，植物，植物组织或其一个或多个部分中生产精细化学品的方法。本发明还涉及核酸分子，多肽，核酸构建体，表达盒，载体，抗体，宿主细胞，植物组织，繁殖材料，收获的材料，植物，微生物以及农业组合物及其用途。

2. 发明申请

US20110145948A1 Transgenic Plants Comprising as Transgene a Phosphatidate Cytidylyltransferase 审中-公开
标题翻译：转基因植物作为转基因磷脂酰胞苷酰转移酶
公开(公告)号：US20110145948A1
公开(公告)日：2011-06-16
申请号：US13058865
申请日：2009-08-10
申请人： Bryan McKersie , Wesley Bruce
发明人： Bryan McKersie , Wesley Bruce
IPC分类号： C12N15/82 , A01H5/00 , C07H21/00
CPC分类号： C12N15/8261 , C07K14/415 , C12N9/1241 , Y02A40/146
摘要： Polynucleotides are disclosed which are capable of enhancing yield of a plant transformed to contain such polynucleotides. Also provided are methods of using such polynucleotides and transgenic plants and agricultural products, including seeds, containing such polynucleotides as transgenes.
摘要翻译：公开了能够增强转化为含有这种多核苷酸的植物的产量的多核苷酸。还提供了使用这种多核苷酸和转基因植物以及含有这种多核苷酸作为转基因的农产品（包括种子）的方法。

3. 发明授权

US08008545B2 Process for the production of fine chemicals 失效
标题翻译：生产精细化学品的工艺
公开(公告)号：US08008545B2
公开(公告)日：2011-08-30
申请号：US10566644
申请日：2004-07-21
申请人： Gunnar Plesch , Piotr Puzio , Astrid Blau , Ralf Looser , Birgit Wendel , Beate Kamlage , Agnes Chardonnens , Amber Shirley , Xi-Qing Wang , Rodrigo Sarria-Millan , Bryan McKersie , Ruoying Chen
发明人： Gunnar Plesch , Piotr Puzio , Astrid Blau , Ralf Looser , Birgit Wendel , Beate Kamlage , Agnes Chardonnens , Amber Shirley , Xi-Qing Wang , Rodrigo Sarria-Millan , Bryan McKersie , Ruoying Chen
IPC分类号： C12N15/82 , C12N15/63
CPC分类号： C12P13/001 , C12N15/8242 , C12P13/04
摘要： The present invention relates to a process for the production of fine chemicals in a microorganism, a plant cell, a plant, a plant tissue or parts thereof by increasing or generating the biological activity of a ras-Like GTPase or the homologues thereof and growing the organism under conditions which permit the production of the fine chemicals in the organism. Preferred fine chemicals produced by the present invention include amino acids, carbohydrates, vitamins, fatty acids, and carotenoids.
摘要翻译：本发明涉及通过增加或产生ras样GTP酶或其同源物的生物活性来生产微生物，植物细胞，植物，植物组织或其部分中的精细化学物质的方法，有机体在允许在生物体中生产精细化学物质的条件下进行。由本发明生产的优选的精细化学品包括氨基酸，碳水化合物，维生素，脂肪酸和类胡萝卜素。

4. 发明申请

US20100162434A1 Yield Increase in Plants Overexpressing the SHSRP Genes 审中-公开
标题翻译：过表达SHSRP基因的植物的产量增加
公开(公告)号：US20100162434A1
公开(公告)日：2010-06-24
申请号：US11988851
申请日：2006-07-13
申请人： Rodrigo Sarria-Millan , Eric R. Garr , Jamie Haertel , Damian Allen , Bryan McKersie
发明人： Rodrigo Sarria-Millan , Eric R. Garr , Jamie Haertel , Damian Allen , Bryan McKersie
IPC分类号： A01H1/00 , A01H5/00 , C12N15/29 , C12N15/63
CPC分类号： C12N15/8227 , C07K14/415 , C12N9/1014 , C12N15/8261 , C12N15/8271 , C12N15/8273 , Y02A40/146
摘要： A transgenic crop plant transformed by a Serine Hydroxymethyltransferase-Like Stress-Related Polypeptide (SHSRP) coding nucleic acid, wherein expression of the nucleic acid sequence in the crop plant results in the plant's increased root growth, and/or increased yield, and/or increased tolerance to environmental stress as compared to a wild type variety of the plant Also provided are agricultural products, including seeds, produced by the transgenic crop plants. Also provided are isolated novel SHSRPs, and isolated novel nucleic acids encoding SHSRPs, and vectors and transgenic plant containing the same.
摘要翻译：通过编码丝氨酸羟甲基转移酶样应激相关多肽（SHSRP）编码核酸转化的转基因作物植物，其中作物植物中核酸序列的表达导致植物的根生长增加和/或增加的产量，和/或与野生型植物相比，增加对环境胁迫的耐受性还提供了由转基因作物植物生产的农产品，包括种子。还提供了分离的新型SHSRP和分离的编码SHSRP的新型核酸，以及含有该SHSRP的载体和转基因植物。

5. 发明申请

US20090217406A1 Plant cells and plants with increased tolerance to environmental stress 审中-公开
标题翻译：具有增加的对环境胁迫耐受性的植物细胞和植物
公开(公告)号：US20090217406A1
公开(公告)日：2009-08-27
申请号：US11663915
申请日：2005-09-23
申请人： Piotr Puzio , Agnes Chardonnens , Harry Wild , Gunnar Plesch , Bryan McKersie
发明人： Piotr Puzio , Agnes Chardonnens , Harry Wild , Gunnar Plesch , Bryan McKersie
IPC分类号： A01H1/02 , C12N5/10 , C12N5/04 , A01H5/00 , A01H7/00 , A01H1/00 , C12N15/74 , C12Q1/02 , C07H21/02 , C07K14/00 , C07K16/00
CPC分类号： C07K14/415 , C12N15/8271 , C12N15/8273
摘要： This invention relates generally to transformed plant cells and plants comprising an inactivated or down-regulated gene resulting in increased tolerance and/or resistance to environmental stress as compared to non-transformed wild type cells and methods of producing such plant cells or plants. This invention further relates generally to transformed plant cells with increased tolerance and/or resistance to an environmental stress as compared to a corresponding non-transformed wild type plant cell, methods of producing, screening for and breeding such plant cells or plants and method of detecting stress in plants cells or plants.
摘要翻译：本发明一般涉及转化的植物细胞和植物，其包含与未转化的野生型细胞相比，导致增加的耐受性和/或耐环境胁迫的基因的失活或下调的基因以及产生这种植物细胞或植物的方法。本发明进一步涉及与相应的未转化的野生型植物细胞相比，具有增加的耐受性和/或耐环境胁迫性的转化植物细胞，生产，筛选和繁殖该植物细胞或植物的方法和检测方法植物细胞或植物的压力。

6. 发明申请

US20130061348A1 Nucleic Acid Sequences Encoding Proteins Associated with Abiotic Stress Responses and Plant Cells with Increased Tolerance to Environmental Stress 审中-公开
标题翻译：编码与非生物胁迫反应和植物细胞相关的蛋白质的核酸序列具有增加的对环境胁迫的耐受性
公开(公告)号：US20130061348A1
公开(公告)日：2013-03-07
申请号：US13549932
申请日：2012-07-16
申请人： Piotr Puzio , Agnes Chardonnens , Amber Shirley , Xi-Qing Wang , Rodrigo Sarria-Millan , Bryan McKersie , Ruoying Chen
发明人： Piotr Puzio , Agnes Chardonnens , Amber Shirley , Xi-Qing Wang , Rodrigo Sarria-Millan , Bryan McKersie , Ruoying Chen
IPC分类号： A01H5/00 , A01H5/10 , C12N15/82 , C12N5/10
CPC分类号： C12N15/8243 , C07K14/245 , C07K14/395 , C07K14/415 , C12N15/8271 , C12N15/8273
摘要： This invention relates generally to nucleic acid sequences encoding proteins that are associated with abiotic stress responses and abiotic stress tolerance in plants. This invention further relates to transformed plant cells with altered metabolic activity compared to a corresponding non transformed wild type plant cell, wherein the metabolic activity is altered by transformation with a Stress-Related Protein (SRP) coding nucleic acid and results in increased tolerance and/or resistance to an environmental stress as compared to a corresponding non-transformed wild type plant cell.
摘要翻译：本发明一般涉及编码与植物中非生物胁迫反应和非生物胁迫耐受相关的蛋白质的核酸序列。本发明还涉及与相应的未转化的野生型植物细胞相比具有改变的代谢活性的转化植物细胞，其中代谢活性通过用编码核酸的胁迫相关蛋白（SRP）转化而改变，并导致增加的耐受性和/ 或与相应的未转化的野生型植物细胞相比对环境胁迫的抗性。

7. 发明授权

US08324455B2 Nucleic acid sequences encoding proteins associated with abiotic stress response and plant cells and plants with increased tolerance to environmental stress 失效
标题翻译：编码与非生物胁迫反应相关的蛋白质的核酸序列和具有增加的对环境胁迫耐受性的植物细胞和植物
公开(公告)号：US08324455B2
公开(公告)日：2012-12-04
申请号：US11663680
申请日：2005-09-23
申请人： Piotr Puzio , Agnes Chardonnens , Harry Wild , Gunnar Plesch , Bryan McKersie
发明人： Piotr Puzio , Agnes Chardonnens , Harry Wild , Gunnar Plesch , Bryan McKersie
IPC分类号： C12N15/82 , A01H5/00 , A01H5/10
CPC分类号： C07K14/415 , C07K14/395 , C12N15/8251 , C12N15/8261 , C12N15/8273 , Y02A40/146
摘要： This invention relates generally to nucleic acid sequences encoding proteins that are associated with abiotic stress responses and abiotic stress tolerance in plants. In particular, this invention relates to nucleic acid sequences encoding proteins that confer drought, heat, cold, and/or salt tolerance to plants.
摘要翻译：本发明一般涉及编码与植物中非生物胁迫反应和非生物胁迫耐受相关的蛋白质的核酸序列。特别地，本发明涉及编码对植物赋予干旱，热，冷和/或耐盐性的蛋白质的核酸序列。

8. 发明申请

US20120227134A1 Plants with Increased Yield 审中-公开
标题翻译：植物增产
公开(公告)号：US20120227134A1
公开(公告)日：2012-09-06
申请号：US13510220
申请日：2010-11-05
申请人： Hardy Schön , Oliver Thimm , Gerhard Ritte , Oliver Bläsing , Stefan Henkes , Koen Bruynseels , Yves Hatzfeld , Valerie Frankard , Ana Isabel Sanz Molinero , Christophe Reuzeau , Steven Vandenabeele , Bryan McKersie , Krishna Kolliparra , Christian Dammann
发明人： Hardy Schön , Oliver Thimm , Gerhard Ritte , Oliver Bläsing , Stefan Henkes , Koen Bruynseels , Yves Hatzfeld , Valerie Frankard , Ana Isabel Sanz Molinero , Christophe Reuzeau , Steven Vandenabeele , Bryan McKersie , Krishna Kolliparra , Christian Dammann
IPC分类号： A01H5/00 , C12P21/00 , C12N5/10 , C12Q1/48 , C12Q1/42 , C12Q1/26 , A01H1/06 , C12Q1/68 , C12N15/52 , C12N15/29 , C07K14/415 , C07K16/16 , A01H5/10 , G01N33/566 , A01N25/00 , A01N43/00 , A01N37/00 , C12N15/82
CPC分类号： C12N15/8261 , C07K14/415 , Y02A40/146
摘要： A method for producing a plant with increased yield as compared to a corresponding wild type plant whereby the method comprises at least the following step: increasing or generating in a plant or a part thereof one or more activities of a polypeptide selected from the group consisting of 2-oxoglutarate-dependent dioxygenase, 3-ketoacyl-CoA thiolase, 3′-phosphoadenosine 5′-phosphate phosphatase, 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, 5OS chloroplast ribosomal protein L21, 57972199. R01.1-protein, 60952769. R01.1-protein, 60S ribosomal protein, ABC transporter family protein, AP2 domain-containing transcription factor, argonaute protein, AT1 G29250.1-protein, AT1 G53885-protein, AT2G35300-protein, AT3G04620-protein, AT4G01870-protein, AT5G42380-protein, AT5G47440-protein, CDS5394-protein, CDS5401_TRUNCATED-protein, cold response protein, cullin, Cytochrome P450, delta-8 sphingolipid desaturase, galactinol synthase, glutathione-S-transferase, GTPase, haspin-related protein, heat shock protein, heat shock transcription factor, histone H2B, jasmonate-zim-domain protein, mitochondrial asparaginyl-tRNA synthetase, Oligosaccharyltransferase, OS02G44730-protein, Oxygen-evolving enhancer protein, peptidyl-prolyl cis-trans isomerase, peptidyl-prolyl cis-trans isomerase family protein, plastid lipid-associated protein, Polypyrimidine tract binding protein, PRLI-interacting factor, protein kinase, protein kinase family protein, rubisco subunit binding-protein beta subunit, serine acetyltransferase, serine hydroxymethyltransferase, small heat shock protein, S-ribosylhomocysteinase, sugar transporter, Thioredoxin H-type, ubiquitin-conjugating enzyme, ubiquitin-protein ligase, universal stress protein family protein, and Vacuolar protein.
摘要翻译：与相应的野生型植物相比，生产具有增加的产量的植物的方法，其中所述方法至少包括以下步骤：在植物或其部分中增加或产生一种或多种选自以下的多肽的活性： 2-氧戊二酸依赖性双加氧酶，3-酮酰基辅酶A硫解酶，3'-磷酸腺苷5'-磷酸磷酸酶，4-二磷酸胞苷-2-C-甲基-D-赤藓糖醇激酶，5OS叶绿体核糖体蛋白L21,57972199。R01.1 蛋白质，60952769.R01.1-蛋白质，60S核糖体蛋白质，ABC转运蛋白家族蛋白质，含AP2结构域的转录因子，argonaute蛋白质，AT1 G29250.1-蛋白质，AT1 G53885-蛋白质，AT2G35300-蛋白质，AT3G04620-蛋白质， AT4G01870蛋白质，AT5G42380蛋白质，AT5G47440蛋白质，CDS5394蛋白质，CDS5401_TRUNCATED蛋白质，冷应答蛋白质，cullin，细胞色素P450，δ-8鞘脂类去饱和酶，肌动蛋白醇合酶，谷胱甘肽-S-转移酶，GTP酶，，热休克蛋白，热休克转录因子，组蛋白H2B，茉莉酸-zim结构域蛋白，线粒体天冬酰胺酰-tRNA合成酶，寡糖转移酶，OS02G44730-蛋白，氧进化增强子蛋白，肽基脯氨酰顺反异构酶，肽基脯氨酰顺式 - 反式异构酶家族蛋白质，质体脂质相关蛋白，聚嘧啶多肽结合蛋白，PRLI相互作用因子，蛋白激酶，蛋白激酶家族蛋白，rubisco亚基结合蛋白β亚基，丝氨酸乙酰转移酶，丝氨酸羟甲基转移酶，小热休克蛋白，S - 糖基半胱氨酸酶，糖转运蛋白，硫氧还蛋白H型，泛素结合酶，泛素 - 蛋白连接酶，通用应激蛋白家族蛋白和Vacuolar蛋白。

9. 发明授权

US08247651B2 Nucleic acid sequences encoding proteins associated with abiotic stress response and plant cells with increased tolerance to environmental stress 失效
标题翻译：编码与非生物胁迫反应相关的蛋白质的核酸序列和对环境胁迫具有增加的耐受性的植物细胞
公开(公告)号：US08247651B2
公开(公告)日：2012-08-21
申请号：US12907438
申请日：2010-10-19
申请人： Piotr Puzio , Agnes Chardonnens , Amber Shirley , Xi-Qing Wang , Rodrigo Sarria-Millan , Bryan McKersie , Ruoying Chen
发明人： Piotr Puzio , Agnes Chardonnens , Amber Shirley , Xi-Qing Wang , Rodrigo Sarria-Millan , Bryan McKersie , Ruoying Chen
IPC分类号： A01H1/00 , C07H21/04 , C07K14/395
CPC分类号： C12N15/8243 , C07K14/245 , C07K14/395 , C07K14/415 , C12N15/8271 , C12N15/8273
摘要： This invention relates generally to nucleic acid sequences encoding proteins that are associated with abiotic stress responses and abiotic stress tolerance in plants. This invention further relates to transformed plant cells with altered metabolic activity compared to a corresponding non transformed wild type plant cell, wherein the metabolic activity is altered by transformation with a Stress-Related Protein (SRP) coding nucleic acid and results in increased tolerance and/or resistance to an environmental stress as compared to a corresponding non-transformed wild type plant cell.
摘要翻译：本发明一般涉及编码与植物中非生物胁迫反应和非生物胁迫耐受相关的蛋白质的核酸序列。本发明还涉及与相应的未转化的野生型植物细胞相比具有改变的代谢活性的转化植物细胞，其中代谢活性通过用编码核酸的胁迫相关蛋白（SRP）转化而改变，并导致增加的耐受性和/ 或与相应的未转化的野生型植物细胞相比对环境胁迫的抗性。

10. 发明申请

US20130276172A1 Yield Increase in Plants Overexpressing the ACCDP Genes 审中-公开
标题翻译：过表达ACCDP基因的植物的产量增加
公开(公告)号：US20130276172A1
公开(公告)日：2013-10-17
申请号：US13316609
申请日：2011-12-12
申请人： Rodrigo Sarria-Millan , Eric R. Garr , Jamie Haertel , Damian Allen , Bryan McKersie
发明人： Rodrigo Sarria-Millan , Eric R. Garr , Jamie Haertel , Damian Allen , Bryan McKersie
IPC分类号： C12N15/82
CPC分类号： C12N15/8261 , C12N9/88 , C12N15/8271 , C12N15/8273 , Y02A40/146
摘要： A transgenic crop plant transformed by a 1-AminoCyclopropane-1-Carboxylate Deaminase-like Polypeptide (ACCDP) coding nucleic acid, wherein expression of the nucleic acid sequence in the crop plant results in the plant's increased root growth, and/or increased yield, and/or increased tolerance to environmental stress as compared to a wild type variety of the plant. Also provided are agricultural products, including seeds, produced by the transgenic crop plants. Also provided are isolated novel ACCDPs, and isolated novel nucleic acids encoding ACCDPs, and vectors and transgenic plant containing the same.
摘要翻译：由1-氨基环丙烷-1-羧酸盐脱氨酶多肽（ACCDP）编码核酸转化的转基因作物植物，其中在作物植物中核酸序列的表达导致植物的根生长增加和/或增加的产量，和/或与植物的野生型品种相比，增加对环境胁迫的耐受性。还提供了由转基因作物植物生产的农产品，包括种子。还提供了分离的新型ACCDP和分离的编码ACCDP的新型核酸，以及载体和含有它们的转基因植物。

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