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    • 5. 发明申请
    • System and method for parallel execution of data generation tasks
    • 并行执行数据生成任务的系统和方法
    • US20060095672A1
    • 2006-05-04
    • US11065343
    • 2005-02-25
    • Jeffrey AndrewsNicholas BakerJ. GoossenMichael AbrashRussell HooverEric MejdrichSandra Woodward
    • Jeffrey AndrewsNicholas BakerJ. GoossenMichael AbrashRussell HooverEric MejdrichSandra Woodward
    • G06F12/14
    • G06F15/7846
    • A CPU module includes a host element configured to perform a high-level host-related task, and one or more data-generating processing elements configured to perform a data-generating task associated with the high-level host-related task. Each data-generating processing element includes logic configured to receive input data, and logic configured to process the input data to produce output data. The amount of output data is greater than an amount of input data, and the ratio of the amount of input data to the amount of output data defines a decompression ratio. In one implementation, the high-level host-related task performed by the host element pertains to a high-level graphics processing task, and the data-generating task pertains to the generation of geometry data (such as triangle vertices) for use within the high-level graphics processing task. The CPU module can transfer the output data to a GPU module via at least one locked set of a cache memory. The GPU retrieves the output data from the locked set, and periodically forwards a tail pointer to a cacheable location within the data-generating elements that informs the data-generating elements of its progress in retrieving the output data
    • CPU模块包括被配置为执行高级主机相关任务的主机元件,以及被配置为执行与高级主机相关任务相关联的数据生成任务的一个或多个数据生成处理元件。 每个数据生成处理元件包括被配置为接收输入数据的逻辑和被配置为处理输入数据以产生输出数据的逻辑。 输出数据量大于输入数据量,并且输入数据量与输出数据量的比率定义了解压比。 在一个实现中,由主机元件执行的与主机相关的高级别任务涉及高级图形处理任务,并且数据生成任务涉及生成几何数据(例如三角形顶点),用于在 高级图形处理任务。 CPU模块可以经由至少一个锁定的高速缓存存储器将输出数据传送到GPU模块。 GPU从锁定的集合中检索输出数据,并周期性地将尾部指针转发到数据生成元素内的可缓存位置,以向数据生成元素通知其在检索输出数据中的进度
    • 8. 发明申请
    • Graphics processor with snoop filter
    • 带窥探过滤器的图形处理器
    • US20060080512A1
    • 2006-04-13
    • US10961750
    • 2004-10-08
    • Russell HooverEric Mejdrich
    • Russell HooverEric Mejdrich
    • G06F12/00
    • G06F12/0831
    • Methods and apparatus that may be utilized to maintain coherency of data accessed by both a processor and a remote device are provided. The remote device may include coherency logic, referred to herein as a snoop filter, designed to filter memory access requests that do not require bus commands to be sent to the processor. The snoop filter may filter requests based on a remote cache directory designed to mirror the processor cache directory, such that only those requests that target cache lines indicated to be valid in the processor cache result in snoop commands sent to the processor. Other requests (targeting data that is not cached in the processor) may be routed directly to memory without the latency conventionally associated with snoop requests.
    • 提供了可用于维护由处理器和远程设备访问的数据的一致性的方法和装置。 远程设备可以包括相关性逻辑,这里称为窥探过滤器,被设计为过滤不需要将总线命令发送到处理器的存储器访问请求。 窥探过滤器可以基于旨在镜像处理器高速缓存目录的远程高速缓存目录来过滤请求,使得仅指示在处理器高速缓存中指示为有效的缓存行的那些请求导致发送到处理器的窥探命令。 其他请求(目标数据不被缓存在处理器中)可以直接路由到存储器,而不需要通常与侦听请求相关联的延迟。
    • 10. 发明申请
    • Effects of combined administration of farnesyl transferase inhibitors and signal transduction inhibitors
    • 联合施用法呢基转移酶抑制剂和信号转导抑制剂的作用
    • US20050020516A1
    • 2005-01-27
    • US10870403
    • 2004-06-17
    • George DaleyRussell Hoover
    • George DaleyRussell Hoover
    • A61K31/473A61K31/495A61K45/06A61P35/02A61K31/704A61K31/33
    • A61K45/06A61K31/473A61K31/495A61K31/435A61K2300/00
    • The present invention relates to methods of reducing proliferation of cells, enhancing apoptosis of cells or both in an individual in need thereof, comprising administering to the individual a combination of at least one farnesyl transferase inhibitor (FTI), such as an inhibitor of Ras function, and at least one signal transduction inhibitor (STI) in a therapeutically effective amount, wherein proliferation of cells is reduced and/or apoptosis of cells is enhanced in the individual. In one embodiment, the invention relates to a method of reducing proliferation of STI resistant cells, enhancing apoptosis of STI resistant cells, or both in an individual in need thereof, comprising administering to the individual a combination of at least one FTI and at least one STI in a therapeutically effective amount, wherein proliferation of STI resistant cells is reduced and/or apoptosis of STI resistant cells is enhanced in the individual. The present invention can be used to treat leukemia (e.g., CML) in an individual comprising administering to the individual a combination of at least one FTI and at least one STI in a therapeutically effective amount.
    • 本发明涉及在有需要的个体中减少细胞增殖,增强细胞凋亡或两者的方法,包括向个体施用至少一种法呢基转移酶抑制剂(FTI)的组合,例如Ras功能抑制剂 ,以及治疗有效量的至少一种信号转导抑制剂(STI),其中细胞的增殖被减少和/或细胞凋亡在个体中增强。 在一个实施方案中,本发明涉及减少STI耐药细胞的增殖,增强STI耐药细胞的凋亡或在有需要的个体中二者的方法,包括向所述个体施用至少一种FTI和至少一种FTI的组合 STI在治疗有效量中,其中STI耐药细胞的增殖减少,和/或STI抗性细胞的细胞凋亡在个体中增强。 本发明可用于治疗个体中的白血病(例如CML),其包括向个体施用治疗有效量的至少一种FTI和至少一种STI的组合。