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1. 发明授权

US5780542A Water-emulsifiable polyisocyanates 失效
标题翻译：水乳化聚异氰酸酯
公开(公告)号：US5780542A
公开(公告)日：1998-07-14
申请号：US679112
申请日：1996-07-12
申请人： Brigitta Huckestein , Hans Renz , Stephan Kothrade , Karl Haberle
发明人： Brigitta Huckestein , Hans Renz , Stephan Kothrade , Karl Haberle
IPC分类号： C08L75/04 , C08G18/00 , C08G18/08 , C08G18/62 , C08G18/70 , C08G18/79 , C08L75/00 , C09D175/00 , C09D175/04 , C09J175/00 , C09J175/04 , C08F283/04
CPC分类号： C08G18/706 , C08G18/6283
摘要： Water-emulsifiable polyisocyanates containing a) aliphatic, cycloaliphatic and aromatic polyisocyanates and b) reaction products of the abovementioned polyisocyanates with polyvinylpyrrolidones which have at least one group which is reactive with isocyanate.
摘要翻译：含有a）脂族，脂环族和芳族多异氰酸酯的水可乳化的多异氰酸酯，和b）上述多异氰酸酯与具有至少一个与异氰酸酯反应的基团的聚乙烯吡咯烷酮的反应产物。

2. 发明授权

US06284803B1 Solid dosage form with polymeric binder 有权
标题翻译：固体剂型与聚合物粘合剂
公开(公告)号：US06284803B1
公开(公告)日：2001-09-04
申请号：US09395775
申请日：1999-09-14
申请人： Stephan Kothrade , Gunther Berndl , Helmut Meffert
发明人： Stephan Kothrade , Gunther Berndl , Helmut Meffert
IPC分类号： A61K4730
CPC分类号： A61K9/2027 , A61K9/2095
摘要： The present invention relates to a solid dosage form comprising at least one polymeric binder and at least one active ingredient and, where appropriate, conventional additives, wherein the polymeric binder consists of copolymerized units a) 15-83% by weight of at least one N-vinyllactam, b) 15-83% by weight of methyl methacrylate, c) 2-70% by weight of at least one other monomer and d) 0-9.9% by weight of at least one &agr;,&bgr;-ethylenically unsaturated acid.
摘要翻译：本发明涉及包含至少一种聚合物粘合剂和至少一种活性成分以及适当的常规添加剂的固体剂型，其中聚合物粘合剂由共聚单元组成a）15-83重量％的至少一个N - 乙烯基内酰胺，b）15-83重量％的甲基丙烯酸甲酯，c）2-70重量％的至少一种其它单体，和d）0-9.9重量％的至少一种α，β-烯属不饱和酸。

3. 发明授权

US06682725B1 High molecular weight mass cationic copolymers 失效
标题翻译：高分子量阳离子共聚物
公开(公告)号：US06682725B1
公开(公告)日：2004-01-27
申请号：US09122097
申请日：1998-07-24
申请人： Reinhold Dieing , Peter Hössel , Stephan Kothrade , Axel Sanner , Katrin Zeitz , Hans-Jürgen Raubenheimer , Volker Schehlmann
发明人： Reinhold Dieing , Peter Hössel , Stephan Kothrade , Axel Sanner , Katrin Zeitz , Hans-Jürgen Raubenheimer , Volker Schehlmann
IPC分类号： A61K706
CPC分类号： A61Q5/12 , A61K8/731 , A61K8/817 , A61K8/8182 , A61K2800/5426 , A61Q5/02
摘要： The disclosure is directed to a process of conditioning hair in which a cosmetic composition is applied to the hair, which composition contains a polymer formed by (i) the free-radically initiated copolymerization of monomer mixtures of (a) from 1 to 99.99% by weight of a cationic monomer or quaternizable monomer, (b) from 0 to 98.99% by weight of a water-soluble monomer, (c) from 0 to 50% by weight of a further free-radically copolymerizable monomer, and (d) from 0.01 to 10% by weight of a bifunctional or polyfunctional, free-radical copolymerizable monomer, and (ii) subsequent quaternization of the polymer if the monomer (a) is a non-quaternized monomer.
摘要翻译：本发明涉及一种调理毛发的方法，其中将化妆品组合物施用于毛发，该组合物含有通过以下步骤形成的聚合物：（i）通过以下方式自由引发共聚单体混合物：（a）1至99.99％阳离子单体或季铵化单体的重量，（b）0至98.99重量％的水溶性单体，（c）0至50重量％的另外的可自由基共聚单体，和（d） 0.01至10重量％的双功能或多官能的自由基可共聚单体，和（ii）如果单体（a）是非季铵化单体，则聚合物的随后季铵化。

4. 发明授权

US07419685B2 Process for producing solid dosage forms 有权
标题翻译：生产固体剂型的方法
公开(公告)号：US07419685B2
公开(公告)日：2008-09-02
申请号：US11039695
申请日：2005-01-21
申请人： Stephan Kothrade , Gunther Berndl , Dirk Simon , Axel Sanner
发明人： Stephan Kothrade , Gunther Berndl , Dirk Simon , Axel Sanner
IPC分类号： A61K9/14 , A61K9/50 , A61K47/32
CPC分类号： C08F279/02 , A61K9/2027 , A61K9/2031 , A61K9/2095 , C08L51/04 , C08F212/08
摘要： Solid dosage forms containing at least one polymer binder, at least one active ingredient and, where appropriate, conventional additives, wherein a physiologically tolerated, water-swellable graft copolymer or a mixture of graft copolymers is employed as polymeric binder.
摘要翻译：包含至少一种聚合物粘合剂，至少一种活性成分和适当的常规添加剂的固体剂型，其中使用生理上耐受的水溶胀性接枝共聚物或接枝共聚物的混合物作为聚合物粘合剂。

5. 发明授权

US06423256B1 Process for producing solid dosage forms 有权
标题翻译：生产固体剂型的方法
公开(公告)号：US06423256B1
公开(公告)日：2002-07-23
申请号：US09417070
申请日：1999-10-13
申请人： Stephan Kothrade , Jörg Breitenbach , Harald Krull , Thomas Kessler , Armin Lange , Werner Maier , Ulrich Reinhold
发明人： Stephan Kothrade , Jörg Breitenbach , Harald Krull , Thomas Kessler , Armin Lange , Werner Maier , Ulrich Reinhold
IPC分类号： A61K920
CPC分类号： A61K31/192 , A61K9/2027 , A61K9/2095
摘要： A process for producing solid dosage forms, in which (i) a plastic mixture of at least one pharmacologically acceptable polymeric binder with a K value of more than 75, at least one pharmaceutical active ingredient and, where appropriate, conventional pharmaceutical additives is prepared and (ii) the plastic mixture is shaped to the required dosage form, with step (i) being carried out under conditions of temperature and shear energy input such that the reduction in molecular weight of the polymeric binder, expressed as the difference in the K value, is less than 15 is described.
摘要翻译：一种制备固体剂型的方法，其中（i）至少一种药理学上可接受的聚合物粘合剂与K值大于75的塑料混合物，至少一种药物活性成分以及适当的常规药物添加剂，以及（ii）将塑料混合物成形为所需剂型，步骤（i）在温度和剪切能量输入条件下进行，使得聚合物粘合剂的分子量的降低表示为K值的差异，小于15被描述。

6. 发明授权

US06350398B1 Process for producing coated solid dosage forms 有权
标题翻译：生产包衣固体剂型的方法
公开(公告)号：US06350398B1
公开(公告)日：2002-02-26
申请号：US09385459
申请日：1999-08-30
申请人： Jörg Breitenbach , Stephan Kothrade , Andreas Kleinke , Armin Lange , Werner Maier
发明人： Jörg Breitenbach , Stephan Kothrade , Andreas Kleinke , Armin Lange , Werner Maier
IPC分类号： A61K932
CPC分类号： A61K9/2095 , A61K9/2893
摘要： The invention relates to a process for producing coated solid dosage forms by forming a plastic mixture from at least one thermoplastic physiologically tolerated polymeric binder and at least one active ingredient and extruding the plastic mixture, wherein the extrudate is subsequently treated with at least one liquid or vaporized coating agent, and the coated extrudate is shaped to the required dosage form.
摘要翻译：本发明涉及通过从至少一种热塑性生理上耐受的聚合物粘合剂和至少一种活性成分形成塑料混合物并挤出塑料混合物来生产涂覆的固体剂型的方法，其中挤出物随后用至少一种液体或蒸发的涂覆剂，并且涂布的挤出物成形为所需的剂型。

7. 发明授权

US06221368B1 Process for producing solid dosage forms by extrusion 有权
标题翻译：通过挤出生产固体剂型的方法
公开(公告)号：US06221368B1
公开(公告)日：2001-04-24
申请号：US09254558
申请日：1999-03-10
申请人： Jörg Breitenbach , Andreas Kleinke , Stephan Kothrade , Joerg Rosenberg
发明人： Jörg Breitenbach , Andreas Kleinke , Stephan Kothrade , Joerg Rosenberg
IPC分类号： A61K900
CPC分类号： A61K9/2095 , A61K9/2027 , A61K9/2086
摘要： A process for producing solid dose forms by mixing at least one polymeric binder, with or without at least one active ingredient and with or without conventional additives, and shaping the mixture, where at least one of the components is employed in liquid form.
摘要翻译：通过混合至少一种具有或不具有至少一种活性成分的聚合物粘合剂以及与或不与常规添加剂混合并且使混合物成形，其中至少一种组分以液体形式使用来生产固体剂型的方法。

8. 发明授权

US06187884B1 Preparation of low molecular mass homopolymers of N-vinylpyrrolidone 失效
标题翻译：低分子量N-乙烯基吡咯烷酮均聚物的制备
公开(公告)号：US06187884B1
公开(公告)日：2001-02-13
申请号：US09104174
申请日：1998-06-25
申请人： Stephan Kothrade , Rainer Blankenburg , Iris Peters , Axel Sanner
发明人： Stephan Kothrade , Rainer Blankenburg , Iris Peters , Axel Sanner
IPC分类号： C08F238
CPC分类号： C08F126/10
摘要： A process for preparing highly concentrated aqueous solutions of low molecular mass homopolymers of N-vinylpyrrolidone by free-radical solution polymerization in an aqueous medium with H2O2 as initiator comprises carrying out the polymerization in the presence of from 0.1 to 30% by weight, based on N-vinylpyrrolidone, of a polymerization regulator which is selected from the group consisting of C1-C6-alkanols, hydroxylamine salts and water-soluble compounds containing sulfur in bonded form.
摘要翻译：通过在具有H 2 O 2作为引发剂的水性介质中通过自由基溶液聚合制备N-乙烯基吡咯烷酮的低分子质量均聚物的高浓度水溶液的方法包括在0.1-30重量％的存在下进行聚合，基于聚合调节剂的N-乙烯基吡咯烷酮，其选自C1-C6-链烷醇，羟胺盐和含有键合形式的硫的水溶性化合物。

9. 发明授权

US6103820A Preparation of water-soluble copolymers of at least one water-soluble N-vinyllactam and at least one hydrophobic comonomer 失效
标题翻译：制备至少一种水溶性N-乙烯基内酰胺和至少一种疏水性共聚单体的水溶性共聚物
公开(公告)号：US6103820A
公开(公告)日：2000-08-15
申请号：US805547
申请日：1997-02-25
申请人： Rainer Blankenburg , Stephan Kothrade , Axel Sanner
发明人： Rainer Blankenburg , Stephan Kothrade , Axel Sanner
IPC分类号： A01N25/00 , A61K8/81 , A61K47/32 , A61Q5/06 , A61Q19/00 , C08F2/10 , C08F2/38 , C08F4/04 , C08F226/06 , C08K3/20
CPC分类号： A61Q5/06 , A61K47/32 , A61K8/817 , A61K8/8182 , A61Q19/00 , C08F226/06
摘要： The present invention relates to a novel process for preparing water-soluble copolymers of at least one water-soluble N-vinyllactam of the formula I ##STR1## where n=1 or 2, and at least one hydrophobic comonomer having a water-solubility of 1 to 85 g/l, by free-radical polymerization in aqueous solution.
摘要翻译：本发明涉及制备至少一种n = 1或2的式I的水溶性N-乙烯基内酰胺和至少一种水溶性为1至85的疏水性共聚单体的水溶性共聚物的新方法 g / l，通过在水溶液中的自由基聚合。

10. 发明授权

US5990269A Copolymer of vinylpyrrolidone and vinylimidazole 失效
标题翻译：乙烯基吡咯烷酮和乙烯基咪唑的共聚物
公开(公告)号：US5990269A
公开(公告)日：1999-11-23
申请号：US975684
申请日：1997-11-21
申请人： Karin Neubecker , Stefan Stien , Stephan Kothrade
发明人： Karin Neubecker , Stefan Stien , Stephan Kothrade
IPC分类号： C08F226/06 , G03F7/00 , G03F7/012 , C08G69/00 , C08F271/02 , C08F279/00
CPC分类号： G03F7/012 , C08F226/06 , G03F7/0007
摘要： The improved water-soluble photosensitive resin composition comprises a high-polymer compound represented by the general formula (I): ##STR1## (where X is Na, K or NH.sub.4) and a water-soluble polymer which is either polyvinylpyrrolidone or a copolymer of vinylpyrrolidone and vinylimidazole or both. The composition is applied to a substrate, exposed through a mask pattern and developed to form a photocured pattern and, thereafter, a light absorber is applied to the entire surface of the substrate and dried, followed by stripping away the photocured pattern and the overlying light absorber to form a black matrix pattern. The composition is suitable for use as a photoresist in the manufacture of black matrices as on color CRTs and capable of efficient formation of photocured patterns with high sensitivity by shorter times and lower intensities of exposure. In addition, the composition adheres strongly to glass substrates and is capable of pattern formation as thin film that is faithful to the mask pattern used. A vinylpyrrolidone/vinylimidazole copolymer is also disclosed.
摘要翻译：改进的水溶性光敏树脂组合物包含由通式（I）表示的高分子化合物：（其中X为Na，K或NH 4）和水溶性聚合物，其为聚乙烯吡咯烷酮或乙烯基吡咯烷酮和乙烯基咪唑的共聚物或两者。将组合物施加到基板上，通过掩模图案曝光并显影以形成光固化图案，然后将光吸收剂施加到基板的整个表面上并干燥，然后剥离光固化图案和上覆光吸收体形成黑色矩阵图案。该组合物适用于在彩色CRT上制造黑色矩阵中的光致抗蚀剂，并且能够通过更短的时间和更低的曝光强度有效地形成具有高灵敏度的光固化图案。此外，组合物强烈地粘附到玻璃基板上，并且能够形成图案，作为忠实于所使用的掩模图案的薄膜。还公开了乙烯基吡咯烷酮/乙烯基咪唑共聚物。

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