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1. 发明申请

US20070167994A1 Telemetry method and apparatus for ambulatory medical device 审中-公开
标题翻译：门诊医疗器械的遥测方法和装置
公开(公告)号：US20070167994A1
公开(公告)日：2007-07-19
申请号：US10596311
申请日：2004-11-17
申请人： Brian Shelton , Sam Bowman
发明人： Brian Shelton , Sam Bowman
IPC分类号： A61N1/00
CPC分类号： A61N1/37252 , A61N1/08 , A61N1/37276 , H04L7/04
摘要： A medical system including an implantable battery operated therapy device and an external communication device configured for wireless communication in a manner to minimize energy consumption in the implanted device. The medical device is configured to wake periodically from a sleep state to look for a message preamble from the communication device. The preamble is formatted to include control information, e.g., information indicating the time of receipt of the forthcoming message.
摘要翻译：一种医疗系统，包括可植入电池操作的治疗装置和被配置为以最小化植入装置中的能量消耗的方式进行无线通信的外部通信装置。医疗设备被配置为周期性地从休眠状态唤醒以从通信设备寻找消息前导码。前导码被格式化以包括控制信息，例如指示即将发送的消息的接收时间的信息。

2. 发明申请

US20060009921A1 Medical device including processor running independent processes to cooperatively control therapy 有权
标题翻译：医疗设备包括处理器运行独立过程，以协同控制治疗
公开(公告)号：US20060009921A1
公开(公告)日：2006-01-12
申请号：US11176857
申请日：2005-07-07
申请人： Brian Shelton , Sam Bowman
发明人： Brian Shelton , Sam Bowman
IPC分类号： G01N31/00
CPC分类号： A61K9/0024
摘要： A medical system comprising an implantable medical device and an external controller. The medical device includes a therapy administration subsystem, a telemetry subsystem, and a control subsystem which includes a microprocessor operable in response to data and/or code provided via said telemetry subsystem for producing an output signal for controlling said therapy administration subsystem. The controller includes a user input means and a telemetry subsystem responsive to said user input means for communicating data and/or code to said medical device telemetry subsystem. The medical device control subsystem includes program means for causing said microprocessor to separately execute at least two software processes to respectively produce separate therapy control output components. Combinatorial logic means responds to the separate output components to produce the output signal for controlling the therapy administration subsystem.
摘要翻译：一种包括可植入医疗装置和外部控制器的医疗系统。医疗设备包括治疗管理子系统，遥测子系统和控制子系统，该控制子系统包括可响应于经由所述遥测子系统提供的数据和/或代码来操作的微处理器，用于产生用于控制所述治疗管理子系统的输出信号。所述控制器包括用户输入装置和响应所述用户输入装置的遥测子系统，用于将数据和/或代码传送到所述医疗装置遥测子系统。医疗设备控制子系统包括用于使所述微处理器分别执行至少两个软件过程以分别产生单独的治疗控制输出组件的程序装置。组合逻辑装置响应于单独的输出组件以产生用于控制治疗管理子系统的输出信号。

3. 发明申请

US20060080654A1 Method and apparatus for upgrading implantable medical device operating software 审中-公开
标题翻译：用于升级植入式医疗器械操作软件的方法和装置
公开(公告)号：US20060080654A1
公开(公告)日：2006-04-13
申请号：US11241085
申请日：2005-09-30
申请人： Brian Shelton
发明人： Brian Shelton
IPC分类号： G06F9/44
CPC分类号： G06F8/65 , G16H40/40
摘要： A method and apparatus for reallocating in the local memory of an implantable medical device for upgrading operating software stored in the Code portion of the local memory. The local memory is managed so that new software e.g., a code segment, is accepted into memory provisionally, and then validated before being used to replace existing (i.e., old) software. Each new segment is received in its entirety and its integrity validated before the old software is overwritten. Data log information is downloaded to an external programmer at the start of a software upgrade operation to temporarily free memory space without losing any information. This freed memory space is then reassigned for the purpose of temporarily storing new code segments until they can be received in their entirety and validated. A software copying component is transferred from a local memory code portion to a data portion to allow new code segments to be written into any area of said code portion.
摘要翻译：一种在可植入医疗设备的本地存储器中重新分配用于升级存储在本地存储器的代码部分中的操作软件的方法和装置。对本地存储器进行管理，使得诸如代码段的新软件被暂时接受到存储器中，然后在用于替换现有的（即，旧的）软件之前被验证。每个新的段被完整地接收，并且其完整性在旧的软件被覆盖之前被验证。数据日志信息在软件升级操作开始时下载到外部程序员，以暂时释放内存空间，而不会丢失任何信息。然后，这个释放的存储器空间被重新分配，用于临时存储新的代码段，直到它们被完整地接收并被验证为止。软件复制组件从本地存储器代码部分传送到数据部分，以允许将新的代码段写入所述代码部分的任何区域。

4. 发明授权

US06564039B1 Frequency generation circuit and method of operating a tranceiver 有权
标题翻译：频率发生电路及操作收发器的方法
公开(公告)号：US06564039B1
公开(公告)日：2003-05-13
申请号：US09515728
申请日：2000-02-29
申请人： Richard B. Meador , Ronald H. Deck , David J. Graham , David H. Minasi , Brian Shelton
发明人： Richard B. Meador , Ronald H. Deck , David J. Graham , David H. Minasi , Brian Shelton
IPC分类号： H04B140
CPC分类号： H04B1/406 , H03L7/23 , H04B2001/0491
摘要： A frequency generation circuit includes an oscillator (403), a comparator (413) coupled to the oscillator, a first divider (407) coupled to the comparator, a PLL (400) coupled to the first divider, a second divider (422) coupled to the PLL, a first multiplexor (409) coupled to the second divider, a third divider (408) coupled to the comparator and the first multiplexor, a second multiplexor (410) coupled to the comparator and the reference clock PLL, a fourth divider (411) coupled to the second multiplexor, a fifth divider (412) coupled to the comparator, and a seventh divider (450) coupled to the comparator. A method of operating a transceiver includes using the frequency generation circuit to provide a first clock signal, a second clock signal, a first reference frequency, and a second reference frequency for a first component, a second component, a third component, and a fourth component, respectively, of the transceiver.
摘要翻译：频率发生电路包括振荡器（403），耦合到振荡器的比较器（413），耦合到比较器的第一分频器（407），耦合到第一分频器的PLL（400），耦合到第一分频器耦合到所述PLL，耦合到所述第二分频器的第一多路复用器（409），耦合到所述比较器和所述第一多路复用器的第三分频器（408），耦合到所述比较器和所述参考时钟PLL的第二多路复用器（410）（411），耦合到所述第二多路复用器，耦合到所述比较器的第五分频器（412）和耦合到所述比较器的第七分频器（450）。操作收发器的方法包括使用频率产生电路为第一组件，第二组件，第三组件和第四组件提供第一时钟信号，第二时钟信号，第一参考频率和第二参考频率分别为收发器。

5. 发明申请

US20060047270A1 Drug delivery apparatus and method for automatically reducing drug dosage 审中-公开
标题翻译：药物输送装置及方法自动降低药物用量
公开(公告)号：US20060047270A1
公开(公告)日：2006-03-02
申请号：US11182307
申请日：2005-07-14
申请人： Brian Shelton
发明人： Brian Shelton
IPC分类号： A61K9/22
CPC分类号： A61M5/14276 , A61K9/0019 , A61K9/0024 , A61K9/0097 , A61M5/16827 , A61M5/172 , A61M2005/14208 , A61M2205/3523 , A61M2205/3561 , A61M2205/52
摘要： A drug delivery device which includes a fluid drug reservoir, a catheter, a controllable fluid transfer device, e.g., a pump mechanism or valve, and a drug delivery control means. The drug delivery control means comprises a controller, e.g., a microprocessor or microcontroller which is operable to automatically reduce the rate of drug delivery over a certain reduction interval (e.g., multiple days) from an initial dosage value to a final dosage value.
摘要翻译：药物输送装置，其包括流体药物储存器，导管，可控流体输送装置，例如泵机构或阀，以及药物输送控制装置。药物递送控制装置包括控制器，例如微处理器或微控制器，其可操作以在从初始剂量值到最终剂量值的特定减少间隔（例如，多天））自动降低药物递送速率。

6. 发明申请

US20050197649A1 Method and apparatus for automatically modifying delivery profile of drug delivery system 有权
标题翻译：用于自动修改药物输送系统的输送方式的方法和装置
公开(公告)号：US20050197649A1
公开(公告)日：2005-09-08
申请号：US11069573
申请日：2005-02-28
申请人： Brian Shelton , Ronald Lebel , Danial Villegas
发明人： Brian Shelton , Ronald Lebel , Danial Villegas
IPC分类号： A61K9/22 , A61M5/142 , A61M5/168 , A61M5/172 , A61M39/02
CPC分类号： A61M5/14276 , A61M5/16827 , A61M5/172 , A61M2005/14208 , A61M2205/52 , G06F19/00 , G06F19/3468
摘要： The present invention relates to an implantable drug delivery device which includes a fluid drug reservoir, a catheter, a controllable fluid transfer device, e.g., a pump or valve, and a drug delivery control means. The control means in accordance with the invention is configured to initially clear a first, or old, drug from the device based on the content of the Current Profile data containing a first, or old, delivery profile. After the old drug is cleared, then the control means automatically modifies the Current Profile data to match a second, or new, delivery profile for controlling delivery of a second, or new, drug.
摘要翻译：本发明涉及一种可植入药物递送装置，其包括流体药物储存器，导管，可控流体输送装置，例如泵或阀，以及药物输送控制装置。根据本发明的控制装置被配置为基于包含第一或更旧的传送简档的当前简档数据的内容来初始地从设备清除第一或旧的药物。在旧药物被清除之后，控制装置自动修改当前配置文件数据以匹配用于控制第二种或新型药物递送的第二种或新型递送配置文件。

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