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1. 发明授权

US08489184B2 System and method for determining electrode-tissue contact based on amplitude modulation of sensed signal 有权
标题翻译：基于感测信号的幅度调制确定电极 - 组织接触的系统和方法
公开(公告)号：US08489184B2
公开(公告)日：2013-07-16
申请号：US13423034
申请日：2012-03-16
申请人： Brian P. Wilfley , Joseph A. Heanue , Stuart L. Friedman
发明人： Brian P. Wilfley , Joseph A. Heanue , Stuart L. Friedman
IPC分类号： A61B5/05
CPC分类号： A61B5/053 , A61B18/1492 , A61B2090/065
摘要： Methods and systems for monitoring contact between a medical probe and tissue are provided. A medical probe is introduced into a patient adjacent the tissue. An electrical parameter, e.g., electrical admittance, is measured between a first electrode located on the medical probe and a second electrode remote from the first electrode. The electrical parameter is amplitude modulated in response to a physiological cycle of the patient. Contact between the medical probe and the tissue is detected based on the amplitude modulation of the measured electrical parameter.
摘要翻译：提供了用于监测医疗探针和组织之间接触的方法和系统。将医用探针引入邻近组织的患者。在位于医疗探针上的第一电极和远离第一电极的第二电极之间测量电参数，例如电导纳。电参数响应于患者的生理周期进行幅度调制。基于所测量的电参数的幅度调制来检测医用探针与组织之间的接触。

2. 发明申请

US20120238897A1 SYSTEM AND METHOD FOR DETERMINING ELECTRODE-TISSUE CONTACT BASED ON AMPLITUDE MODULATION OF SENSED SIGNAL 有权
标题翻译：基于感应信号振幅调制的电极组织接触测定系统及方法
公开(公告)号：US20120238897A1
公开(公告)日：2012-09-20
申请号：US13423034
申请日：2012-03-16
申请人： Brian P. Wilfley , Joseph A. Heanue , Stuart L. Friedman
发明人： Brian P. Wilfley , Joseph A. Heanue , Stuart L. Friedman
IPC分类号： A61B5/053
CPC分类号： A61B5/053 , A61B18/1492 , A61B2090/065
摘要： Methods and systems for monitoring contact between a medical probe and tissue are provided. A medical probe is introduced into a patient adjacent the tissue. An electrical parameter, e.g., electrical admittance, is measuring between a first electrode located on the medical probe and a second electrode remote from the first electrode. The electrical parameter is amplitude modulated in response to a physiological cycle of the patient. Contact between the medical probe and the tissue is detected based on the amplitude modulation of the measured electrical parameter.
摘要翻译：提供了用于监测医疗探针和组织之间接触的方法和系统。将医用探针引入邻近组织的患者。诸如电导纳的电参数是在位于医用探针上的第一电极和远离第一电极的第二电极之间进行测量。电参数响应于患者的生理周期进行幅度调制。基于所测量的电参数的幅度调制来检测医用探针与组织之间的接触。

3. 发明授权

US08160690B2 System and method for determining electrode-tissue contact based on amplitude modulation of sensed signal 有权
标题翻译：基于感测信号的幅度调制确定电极 - 组织接触的系统和方法
公开(公告)号：US08160690B2
公开(公告)日：2012-04-17
申请号：US11762778
申请日：2007-06-14
申请人： Brian P. Wilfley , Joseph A. Heanue , Stuart L. Friedman
发明人： Brian P. Wilfley , Joseph A. Heanue , Stuart L. Friedman
IPC分类号： A61B5/05
CPC分类号： A61B5/053 , A61B18/1492 , A61B2090/065
摘要： Methods and systems for monitoring contact between a medical probe and tissue are provided. A medical probe is introduced into a patient adjacent the tissue. An electrical parameter, e.g., electrical admittance, is measured between a first electrode located on the medical probe and a second electrode remote from the first electrode. The electrical parameter is amplitude modulated in response to a physiological cycle of the patient. Contact between the medical probe and the tissue is detected based on the amplitude modulation of the measured electrical parameter.
摘要翻译：提供了用于监测医疗探针和组织之间接触的方法和系统。将医用探针引入邻近组织的患者。在位于医疗探针上的第一电极和远离第一电极的第二电极之间测量电参数，例如电导纳。电参数响应于患者的生理周期进行幅度调制。基于所测量的电参数的幅度调制来检测医用探针与组织之间的接触。

4. 发明申请

US20080312713A1 SYSTEM AND METHOD FOR DETERMINING ELECTRODE-TISSUE CONTACT BASED ON AMPLITUDE MODULATION OF SENSED SIGNAL 有权
标题翻译：基于感应信号振幅调制的电极组织接触测定系统及方法
公开(公告)号：US20080312713A1
公开(公告)日：2008-12-18
申请号：US11762778
申请日：2007-06-14
申请人： Brian P. Wilfley , Joseph A. Heanue , Stuart L. Friedman
发明人： Brian P. Wilfley , Joseph A. Heanue , Stuart L. Friedman
IPC分类号： A61N1/02 , A61B18/14
CPC分类号： A61B5/053 , A61B18/1492 , A61B2090/065
摘要： Methods and systems for monitoring contact between a medical probe and tissue are provided. A medical probe is introduced into a patient adjacent the tissue. An electrical parameter, e.g., electrical admittance, is measuring between a first electrode located on the medical probe and a second electrode remote from the first electrode. The electrical parameter is amplitude modulated in response to a physiological cycle of the patient. Contact between the medical probe and the tissue is detected based on the amplitude modulation of the measured electrical parameter.
摘要翻译：提供了用于监测医疗探针和组织之间接触的方法和系统。将医用探针引入邻近组织的患者。诸如电导纳的电参数是在位于医用探针上的第一电极和远离第一电极的第二电极之间进行测量。电参数响应于患者的生理周期进行幅度调制。基于所测量的电参数的幅度调制来检测医用探针与组织之间的接触。

5. 发明授权

US06717146B2 Tandem microchannel plate and solid state electron detector 失效
标题翻译：串联微通道板和固态电子检测器
公开(公告)号：US06717146B2
公开(公告)日：2004-04-06
申请号：US09866361
申请日：2001-05-24
申请人： Tai-Hon Philip Chang , Stuart L. Friedman , Ming L. Yu
发明人： Tai-Hon Philip Chang , Stuart L. Friedman , Ming L. Yu
IPC分类号： G03G1300
CPC分类号： H01J37/244 , G01N23/225
摘要： A compact detector for secondary and backscattered electrons in a scanning electron beam system includes a microchannel plate detector and a solid state detector connected in a tandem manner. The detector offers large bandwidth and high dynamic range. The detector can be used for article inspection, lithography, metrology, and other related applications. The compactness of the detector makes it ideally suited for utilization in a miniature electron beam column, such as a microcolumn.
摘要翻译：用于扫描电子束系统中的二次和反向散射电子的紧凑型检测器包括微通道板检测器和以串联方式连接的固态检测器。该检测器提供大带宽和高动态范围。检测器可用于物品检查，光刻，计量和其他相关应用。检测器的紧凑性使其非常适用于微型电子束柱（如微柱）的应用。

6. 发明授权

US07570354B1 Image intensification for low light inspection 有权
标题翻译：低光检查图像强化
公开(公告)号：US07570354B1
公开(公告)日：2009-08-04
申请号：US11876009
申请日：2007-10-22
申请人： Wei Zhao , Stuart L. Friedman
发明人： Wei Zhao , Stuart L. Friedman
IPC分类号： G01N21/88
CPC分类号： G01N21/8851 , G01N21/9501 , H01J9/42 , H01J31/26
摘要： An optical inspection system for inspecting a substrate. A beam source produces a light beam and directs it toward a surface of the substrate, thereby producing a reflected light beam that is received by an intensifier module. A photocathode receives the reflected light beam at a first surface and producing a shower of photoelectrons at a second opposing surface. An electrical field receives the shower of photoelectrons and accelerates the photoelectrons away from the second surface of the photocathode, thereby producing an enhanced output. A sensor receives the enhanced output from the intensifier module and produces electrical signals in response to the enhanced output. A controller receives the electrical signals and produces images of the substrate, based at least in part on the electrical signals. The controller also controls and coordinates the operation of the beam source, the intensifier module, and the sensor.
摘要翻译：用于检查基板的光学检查系统。光束源产生光束并将其引导到衬底的表面，从而产生被增强器模块接收的反射光束。光电阴极在第一表面处接收反射光束并且在第二相对表面处产生光电子的喷淋。电场接收光电子的喷淋并使光电子从光电阴极的第二表面加速，从而产生增强的输出。传感器从增强器模块接收增强的输出并响应增强的输出产生电信号。控制器至少部分地基于电信号接收电信号并产生衬底的图像。控制器还控制和协调光束源，增强器模块和传感器的操作。

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