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1. 发明申请

US20070244402A1 System and method of monitoring physiological signals 审中-公开
标题翻译：监测生理信号的系统和方法
公开(公告)号：US20070244402A1
公开(公告)日：2007-10-18
申请号：US11677015
申请日：2007-02-20
申请人： Brian Brockway , Vladimir Kovtun , Carlos Ricci , John Arnold , Keith Jasperson , Kathy Sherwood , Scott Mazar
发明人： Brian Brockway , Vladimir Kovtun , Carlos Ricci , John Arnold , Keith Jasperson , Kathy Sherwood , Scott Mazar
IPC分类号： A61B5/0402
CPC分类号： A61B5/046 , A61B5/0006 , A61B5/7275 , A61N1/3702 , G16H40/63 , G16H50/30
摘要： A physiological signal monitoring and analysis system including an implantable medical device and a signal processor. The implantable medical device is configured to monitor and record sample segments of at least one physiological signal of a patient at time separated recording intervals over a time period. The signal processor configured to measure values of at least one selected characteristic of the at least one physiological signal from the recorded sample segments, to determine trend information representing a trend in the at least one selected characteristic based on the measured values, and to assess a risk of a physiological event to the patient based on the trend information.
摘要翻译：一种生理信号监测和分析系统，包括可植入医疗装置和信号处理器。可植入医疗装置被配置为在一段时间内以分开的时间间隔监视和记录患者的至少一个生理信号的样本片段。所述信号处理器被配置为测量来自所记录的样本片段的至少一个生理信号的至少一个所选特征的值，以基于所述测量值确定表示所述至少一个所选特征中的趋势的趋势信息，并且评估根据趋势信息向患者发生生理事件的风险。

2. 发明授权

US09186089B2 Injectable physiological monitoring system 有权
标题翻译：注射生理监测系统
公开(公告)号：US09186089B2
公开(公告)日：2015-11-17
申请号：US12209479
申请日：2008-09-12
申请人： Scott Mazar , Mark Bly
发明人： Scott Mazar , Mark Bly
IPC分类号： A61B5/02 , A61B5/07 , A61B5/00 , A61B5/145 , A61B5/0205 , A61B5/053 , A61N1/372
CPC分类号： A61B5/7282 , A61B5/0031 , A61B5/0205 , A61B5/02055 , A61B5/0422 , A61B5/053 , A61B5/07 , A61B5/076 , A61B5/1118 , A61B5/14503 , A61B5/4875 , A61B5/686 , A61B5/7232 , A61B2560/0214 , A61B2560/0468 , A61B2562/0219 , A61B2562/04 , A61B2562/06 , A61B2562/16 , A61N1/37205 , G06F19/00
摘要： A system and method for decompensation prediction of a heart failure patient with one or more injectable detecting systems communicating wirelessly with a remote monitoring system. The system includes one or more injectable detecting systems having a plurality of sensors that provide an indication of at least one physiological event of a patient, a wireless communication device coupled to the one or more injectable detecting systems and configured to transfer patient data directly or indirectly from the one or more injectable detecting systems to a remote monitoring system, and a remote monitoring system coupled to the wireless communication device, the remote monitoring system using processed data to determine heart failure status and predict impending decompensation of the patient.
摘要翻译：一种用于与一个或多个与远程监测系统无线通信的可注射检测系统的心力衰竭患者的失代偿预测的系统和方法。该系统包括一个或多个可注射检测系统，其具有提供患者至少一个生理事件的指示的多个传感器，耦合到该一个或多个可注射检测系统并被配置为直接或间接转移患者数据的无线通信设备从所述一个或多个可注射检测系统到远程监控系统以及耦合到所述无线通信设备的所述远程监控系统，所述远程监控系统使用处理的数据来确定心力衰竭状态并预测所述患者的即将失代偿失调。

3. 发明授权

US08374693B2 Systems and methods for timing-based communication between implantable medical devices 有权
标题翻译：可植入式医疗设备之间基于定时通信的系统和方法
公开(公告)号：US08374693B2
公开(公告)日：2013-02-12
申请号：US11186245
申请日：2005-07-21
申请人： Abhijeet V. Chavan , Jeffrey A. Von Arx , Scott Mazar
发明人： Abhijeet V. Chavan , Jeffrey A. Von Arx , Scott Mazar
IPC分类号： A61N1/32
CPC分类号： A61M5/14276 , A61M2205/3523 , A61M2205/3569 , A61M2205/8212 , A61N1/37276 , A61N1/378 , A61N1/3962 , A61N1/3975
摘要： A method carried out by an implantable medical device (IMD) for coordinating performance of one or more designated functions includes waiting in a low-power state for a predetermined event, detecting the predetermined event, and, responsive to detecting the predetermined event, searching for a wake-up command from a coordinating device implanted in the human body. The method further includes, receiving the wake-up command, and responsive to receiving the wake-up command, performing the one or more designated functions, and returning to the low-power state. A system includes a network of one or more implantable medical devices (IMDs) implanted in a human body. The system includes a satellite IMD operable to change between a plurality of power states, search for a wake-up command, and transmit an identification signal. The system may include a primary unit operable to receive the signal and coordinate a wake-up time based on the signal.
摘要翻译：用于协调一个或多个指定功能的性能的可植入医疗装置（IMD）执行的方法包括在低功率状态下等待预定事件，检测预定事件，并且响应于检测到预定事件，搜索来自植入人体的协调装置的唤醒命令。该方法还包括：接收唤醒命令，并响应于接收到唤醒命令，执行一个或多个指定功能，并返回到低功率状态。一种系统包括植入人体内的一个或多个可植入医疗装置（IMD）的网络。该系统包括可操作以在多个功率状态之间切换，搜索唤醒命令并发送识别信号的卫星IMD。系统可以包括主单元，其可操作以接收信号并且基于该信号来协调唤醒时间。

4. 发明申请

US20080103407A1 Obstructive sleep apnea treatment devices, systems and methods 有权
公开(公告)号：US20080103407A1
公开(公告)日：2008-05-01
申请号：US11907532
申请日：2007-10-12
申请人： Stephen Bolea , Thomas Hoegh , Bruce Persson , Robert Atkinson , Scott Mazar
发明人： Stephen Bolea , Thomas Hoegh , Bruce Persson , Robert Atkinson , Scott Mazar
IPC分类号： A61N1/05 , A61B5/08
CPC分类号： A61N1/3606 , A61B5/0809 , A61B5/4818 , A61B5/7239 , A61N1/0556 , A61N1/0558 , A61N1/3601 , A61N1/37229
摘要： Devices, systems and methods for nerve stimulation for OSA therapy.

5. 发明申请

US20060195163A1 METHOD AND APPARATUS FOR ESTABLISHING CONTEXT AMONG EVENTS AND OPTIMIZING IMPLANTED MEDICAL DEVICE PERFORMANCE 有权
标题翻译：建立事件背景和优化医疗器械性能的方法和装置
公开(公告)号：US20060195163A1
公开(公告)日：2006-08-31
申请号：US11381051
申请日：2006-05-01
申请人： Bruce KenKnight , Eric Lovett , Robert Sweeney , Scott Mazar , Yatheendhar Manicka
发明人： Bruce KenKnight , Eric Lovett , Robert Sweeney , Scott Mazar , Yatheendhar Manicka
IPC分类号： A61N1/08
CPC分类号： A61N1/36514 , A61N1/3627 , A61N1/37211 , A61N1/37235 , A61N1/37282 , G06F19/00
摘要： An apparatus and method for adjusting the performance of an implanted device based on data including contextual information. Contextual information, including operational and performance data concerning the implanted device as well as the patient with the implanted device, is stored by a portable electronic device. In one embodiment, the portable electronic device is adapted for battery operation and includes a personal digital assistant (PDA). The portable electronic device is adapted for use as an interface to conduct wireless communications with the implanted device. In one embodiment, the portable electronic device interfaces with a clinical programmer for use by a physician.
摘要翻译：一种用于基于包括上下文信息的数据来调整植入装置的性能的装置和方法。上下文信息，包括关于植入装置的操作和性能数据以及具有植入装置的患者，由便携式电子装置存储。在一个实施例中，便携式电子设备适用于电池操作并且包括个人数字助理（PDA）。便携式电子设备适于用作与植入的设备进行无线通信的接口。在一个实施例中，便携式电子设备与临床程序员接口以供医生使用。

6. 发明申请

US20060122667A1 Systems and methods for timing-based communication between implantable medical devices 有权
公开(公告)号：US20060122667A1
公开(公告)日：2006-06-08
申请号：US11186245
申请日：2005-07-21
申请人： Abhijeet Chavan , Jeffrey Von Arx , Scott Mazar
发明人： Abhijeet Chavan , Jeffrey Von Arx , Scott Mazar
IPC分类号： A61N1/08
CPC分类号： A61M5/14276 , A61M2205/3523 , A61M2205/3569 , A61M2205/8212 , A61N1/37276 , A61N1/378 , A61N1/3962 , A61N1/3975
摘要： A method carried out by an implantable medical device (IMD) for coordinating performance of one or more designated functions includes waiting in a low-power state for a predetermined event, detecting the predetermined event, and, responsive to detecting the predetermined event, searching for a wake-up command from a coordinating device implanted in the human body. The method further includes, receiving the wake-up command, and responsive to receiving the wake-up command, performing the one or more designated functions, and returning to the low-power state. A system includes a network of one or more implantable medical devices (IMDs) implanted in a human body. The system includes a satellite IMD operable to change between a plurality of power states, search for a wake-up command, and transmit an identification signal. The system may include a primary unit operable to receive the signal and coordinate a wake-up time based on the signal.

7. 发明申请

US20060064143A1 Systems and methods for deriving relative physiologic measurements using a backend computing system 有权
标题翻译：使用后端计算系统导出相对生理测量的系统和方法
公开(公告)号：US20060064143A1
公开(公告)日：2006-03-23
申请号：US10943627
申请日：2004-09-17
申请人： Jeffrey Von Arx , Scott Mazar , Abhi Chavan
发明人： Jeffrey Von Arx , Scott Mazar , Abhi Chavan
IPC分类号： A61N1/08
CPC分类号： A61N1/37252 , A61B5/0031 , A61M5/14276 , A61M5/1723 , A61M2205/3523 , A61M2205/52 , A61M2230/30 , A61N1/37217 , A61N1/37223 , G06F19/00
摘要： One embodiment of the present invention relates to a system for deriving physiologic measurement values that are relative to ambient conditions. In one embodiment, the system comprises an implantable medical device (“IMD”), an external computing device, and a backend computing system. The IMD determines an absolute physiologic parameter value within a patient's body, and communicates the absolute physiologic parameter value outside the patient's body, for example, to the external computing device. Further, the external computing device receives the absolute physiologic parameter from the IMD and communicates it to the backend computing system. The backend computing system receives the absolute physiologic parameter value and obtains an ambient condition value outside the body that can affect the absolute physiologic parameter value. The backend computing system then calculates a relative physiologic parameter value from the ambient condition value and the absolute physiologic parameter value, and in some embodiments, stores the relative physiologic parameter value in a storage location, such as a memory or database.
摘要翻译：本发明的一个实施例涉及用于导出相对于环境条件的生理测量值的系统。在一个实施例中，该系统包括可植入医疗装置（“IMD”），外部计算装置和后端计算系统。 IMD确定患者体内的绝对生理参数值，并将例如外部计算设备的绝对生理参数值传达到患者体外。此外，外部计算设备从IMD接收绝对生理参数并将其传送到后端计算系统。后端计算系统接收绝对生理参数值，并获得可能影响绝对生理参数值的身体外部的环境条件值。后端计算系统然后根据环境条件值和绝对生理参数值计算相对生理参数值，并且在一些实施例中，将相对生理参数值存储在诸如存储器或数据库的存储位置中。

8. 发明申请

US20090076350A1 Data Collection in a Multi-Sensor Patient Monitor 审中-公开
标题翻译：多传感器患者监护仪中的数据收集
公开(公告)号：US20090076350A1
公开(公告)日：2009-03-19
申请号：US12209528
申请日：2008-09-12
申请人： Mark Bly , Kristofer James , Imad Libbus , Scott Mazar , Jerry Wang
发明人： Mark Bly , Kristofer James , Imad Libbus , Scott Mazar , Jerry Wang
IPC分类号： A61B5/00
CPC分类号： A61N1/08 , A61B5/0006 , A61B5/02055 , A61B5/021 , A61B5/024 , A61B5/02405 , A61B5/04085 , A61B5/053 , A61B5/0816 , A61B5/1116 , A61B5/1118 , A61B5/145 , A61B5/6833 , A61B7/00 , A61B2560/0209 , A61B2560/0412 , A61N1/37282
摘要： A system for tracking a patient's physiological status and detecting and predicting negative physiological events, with a detecting system and a remote monitoring system. The detecting system includes a plurality of sensors that provide an indication of at least one physiological event of a patient, and a wireless communication device coupled to the plurality of sensors, and configured to transfer patient data from the plurality of sensors to a remote monitoring system. The a remote monitoring system coupled to the wireless communication device, wherein during a registration period, the detecting system being activated for a first time and communicating with the remote monitoring system to register the detecting system and activate data logging.
摘要翻译：利用检测系统和远程监控系统跟踪患者的生理状况和检测和预测负面生理事件的系统。所述检测系统包括多个传感器，其提供患者的至少一个生理事件的指示，以及耦合到所述多个传感器的无线通信设备，并且被配置为将患者数据从所述多个传感器传送到远程监控系统。一种耦合到所述无线通信设备的远程监控系统，其中在注册期间，所述检测系统被第一次激活，并且与所述远程监控系统通信以注册所述检测系统并激活数据记录。

9. 发明申请

US20090076348A1 Injectable Device for Physiological Monitoring 有权
标题翻译：用于生理监测的注射装置
公开(公告)号：US20090076348A1
公开(公告)日：2009-03-19
申请号：US12209430
申请日：2008-09-12
申请人： Yatheendhar D. Manicka , Badri Amurthur , Mark Bly , Kristofer James , Imad Libbus , Scott Mazar , Jerry Wang
发明人： Yatheendhar D. Manicka , Badri Amurthur , Mark Bly , Kristofer James , Imad Libbus , Scott Mazar , Jerry Wang
IPC分类号： A61B5/00
CPC分类号： A61B5/7282 , A61B5/0031 , A61B5/0205 , A61B5/02055 , A61B5/0422 , A61B5/053 , A61B5/07 , A61B5/076 , A61B5/1118 , A61B5/14503 , A61B5/4875 , A61B5/686 , A61B5/7232 , A61B2560/0214 , A61B2560/0468 , A61B2562/0219 , A61B2562/04 , A61B2562/06 , A61B2562/16 , A61N1/37205 , G06F19/00
摘要： An injectable detecting device is provided for use in physiological monitoring. The device includes a plurality of sensors axially spaced along a body that provide an indication of at least one physiological event of a patient, a monitoring unit within the body coupled to the plurality of sensors configured to receive data from the plurality of sensors and create processed patient data, a power source within the body coupled to the monitoring unit, and a communication antenna external to the body coupled to the monitoring unit configured to transfer data to/from other devices.
摘要翻译：提供可用于生理监测的可注射检测装置。该装置包括沿主体轴向间隔开的多个传感器，其提供患者的至少一个生理事件的指示;耦合到多个传感器的身体内的监测单元，其配置成从多个传感器接收数据并产生处理患者数据，耦合到监测单元的身体内的电源，以及耦合到监视单元的身体外部的通信天线，该通信天线被配置为向/从其他设备传送数据。

10. 发明申请

US20080024294A1 SYSTEMS, DEVICES, AND METHODS FOR SELECTIVELY PREVENTING DATA TRANSFER FROM A MEDICAL DEVICE 有权
标题翻译：用于选择性地防止从医疗设备传送数据的系统，设备和方法
公开(公告)号：US20080024294A1
公开(公告)日：2008-01-31
申请号：US11869639
申请日：2007-10-09
申请人： Scott Mazar
发明人： Scott Mazar
IPC分类号： G08B1/08 , A61B5/00
CPC分类号： H04K3/86 , H04K3/41 , H04K3/45 , H04K3/825 , H04K2203/16
摘要： Systems and methods provide for the selective prevention of data transfer from a medical device to allow the patient to have privacy when desired. Theses systems and methods provide medical devices that can be instructed in various ways to stop recording data and/or transmitting data to external devices and systems. These systems and methods also provide external repeater devices that can also be instructed in various ways to stop recording data being received, stop forwarding data that is being or has already been received, and/or to stop soliciting data from the medical device. These systems and methods also provide for a blocking device that may be separate from the medical device and repeater to provide instruction to the medical device and/or repeater to prevent data transfer such as by stopping the recording or transmission of data. Further, the blocking device may be alternatively configured to provide a jamming signal to prevent data transmissions from being successfully communicated between the medical device and the repeater.
摘要翻译：系统和方法提供选择性地防止从医疗设备传输数据，以允许患者在需要时具有隐私。这些系统和方法提供可以以各种方式指示的医疗设备来停止向外部设备和系统记录数据和/或传送数据。这些系统和方法还提供外部中继器设备，其还可以以各种方式指示停止记录正在接收的数据，停止正在或已被接收的数据，和/或停止从医疗设备请求数据。这些系统和方法还提供了可以与医疗设备和中继器分离的阻塞设备，以向医疗设备和/或中继器提供指令以防止数据传输，例如通过停止数据的记录或传输。此外，阻挡装置可以可选地配置成提供干扰信号，以防止在医疗装置和中继器之间成功通信数据传输。

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