专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20070249636A1 Selected Fused Heterocyclics and Uses Thereof 审中-公开
标题翻译：所选熔融杂环及其用途
公开(公告)号：US20070249636A1
公开(公告)日：2007-10-25
申请号：US11573671
申请日：2005-08-16
申请人： Brian Aquila , Michael Block , Audrey Davies , Jayachandran Ezhuthachan , Timothy Pontz , Daniel Russell , Marie-Elena Theoclitou , XiaoLan Zheng
发明人： Brian Aquila , Michael Block , Audrey Davies , Jayachandran Ezhuthachan , Timothy Pontz , Daniel Russell , Marie-Elena Theoclitou , XiaoLan Zheng
IPC分类号： A61K31/519 , A61P35/00 , C07D239/00 , C07D261/00 , C07D275/00 , C07D487/14 , C07D498/04 , C07D513/04
CPC分类号： C07D513/04
摘要： This invention relates to novel compounds having the structural formula (I) and to their pharmaceutical compositions and to their methods of use. These novel compounds provide a treatment or prophylaxis of cancer.
摘要翻译：本发明涉及具有结构式（I）的新化合物及其药物组合物及其使用方法。这些新化合物提供癌症的治疗或预防。

2. 发明申请

US20060063751A1 Novel fused heterocycles and uses thereof 审中-公开
标题翻译：新型稠合杂环及其用途
公开(公告)号：US20060063751A1
公开(公告)日：2006-03-23
申请号：US11207089
申请日：2005-08-18
申请人： Brian Aquila , Michael Block , Audrey Davies , Jayachandran Ezhuthachan , Sandra Filla , Richard Luke , Timothy Pontz , Daniel Russell , Maria-Elena Theoclitou , XiaoLan Zheng
发明人： Brian Aquila , Michael Block , Audrey Davies , Jayachandran Ezhuthachan , Sandra Filla , Richard Luke , Timothy Pontz , Daniel Russell , Maria-Elena Theoclitou , XiaoLan Zheng
IPC分类号： A61K31/513 , C07D417/02 , C07D413/02 , C07D403/02
CPC分类号： C07D513/04
摘要： This invention relates to novel compounds having the formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8 and R9 are as defined in the specification and to their pharmaceutical compositions and to their methods of use. These novel compounds provide a treatment or prophylaxis of cancer.
摘要翻译：本发明涉及具有式（I）的新化合物，

3. 发明申请

US20060041128A1 Selected fused heterocyclics and uses thereof 审中-公开
标题翻译：所选稠合杂环及其用途
公开(公告)号：US20060041128A1
公开(公告)日：2006-02-23
申请号：US11206888
申请日：2005-08-18
申请人： Brian Aquila , Michael Block , Audrey Davies , Jayachandran Ezhuthachan , Timothy Pontz , Daniel Russell , Maria-Elena Theoclitou , XiaoLan Zheng
发明人： Brian Aquila , Michael Block , Audrey Davies , Jayachandran Ezhuthachan , Timothy Pontz , Daniel Russell , Maria-Elena Theoclitou , XiaoLan Zheng
IPC分类号： A61K31/519 , C07D498/02 , C07D491/02
CPC分类号： C07D513/04
摘要： This invention relates to novel compounds having the structural formula (I) and to their pharmaceutical compositions and to their methods of use. These novel compounds provide a treatment or prophylaxis of cancer.
摘要翻译：本发明涉及具有结构式（I）的新化合物及其药物组合物及其使用方法。这些新化合物提供癌症的治疗或预防。

4. 发明申请

US20070287703A1 Fused Pyrimidones Useful in the Treatment and the Prevention of Cancer 审中-公开
标题翻译：用于治疗和预防癌症的融合嘧啶酮
公开(公告)号：US20070287703A1
公开(公告)日：2007-12-13
申请号：US11572445
申请日：2005-07-21
申请人： Michael Block , Audrey Davies , Daniel Russell , Marie-Elena Theoclitou
发明人： Michael Block , Audrey Davies , Daniel Russell , Marie-Elena Theoclitou
IPC分类号： A61K31/517 , A61K31/54 , A61P35/04 , C07D239/70 , C07D417/04
CPC分类号： C07D471/04 , C07D513/04
摘要： Compounds which possess Eg5 inhibitory activity and are useful for their anti-cell-proliferation (such as anti-cancer) activity and thus in methods of treatment of the human or animal body are described.
摘要翻译：描述了具有Eg5抑制活性并可用于其抗细胞增殖（例如抗癌）活性以及因此用于人或动物体的治疗方法的化合物。

5. 发明申请

US20160036545A1 Measuring device and measuring method for start time synchronized signal generation 有权
标题翻译：用于启动时间同步信号产生的测量装置和测量方法
公开(公告)号：US20160036545A1
公开(公告)日：2016-02-04
申请号：US14814777
申请日：2015-07-31
申请人： Ralf Plaumann , Feng Xie , Thomas Lutz , Michael Block , Hailiang Jin
发明人： Ralf Plaumann , Feng Xie , Thomas Lutz , Michael Block , Hailiang Jin
IPC分类号： H04J3/14 , H04B17/00
CPC分类号： H04B17/0085 , G01R27/28 , H04L1/20 , H04L1/24
摘要： A measuring system comprises a timing unit and at least two signal generators. The signal generators are each configured to generate a measuring signal and to supply it to a device under test. The timing unit is configured to generate start time signals, which each indicate an allowed start time of the measuring signals. Said signal generators are configured to only start generating the measuring signals at least instances of start time signals.
摘要翻译：测量系统包括定时单元和至少两个信号发生器。信号发生器各自被配置为产生测量信号并将其提供给被测设备。定时单元被配置为产生起始时间信号，每个起始时间信号指示测量信号的允许的开始时间。所述信号发生器被配置为仅在开始时间信号的至少一些情况下开始产生测量信号。

6. 发明授权

US08757939B1 Drill bit jig 有权
标题翻译：钻头夹具
公开(公告)号：US08757939B1
公开(公告)日：2014-06-24
申请号：US12650987
申请日：2009-12-31
申请人： Michael Block
发明人： Michael Block
IPC分类号： B23B47/26
CPC分类号： B23B47/287 , B23B2247/12
摘要： A drill bit jig includes an elongate member, two jig securing elements and a rotatable drill bit guide. The elongate member is hollow so that one or more elongate drill bits may be stored therein. The drill bit guide includes a plurality of through holes where the axes of the through holes are parallel to the axis of the elongate member. Each of the plurality of through holes in the drill bit guide has a different diameter for accommodating drill bits of different thicknesses. The jig securing elements each include an L-shaped bolt and a door protecting material encasing one of the straight sections of the bolt.
摘要翻译：钻头夹具包括细长构件，两个夹具固定元件和可旋转的钻头引导件。细长构件是中空的，使得可以在其中存储一个或多个细长钻头。钻头引导件包括多个通孔，其中通孔的轴线平行于细长构件的轴线。钻头引导件中的多个通孔中的每一个具有不同的直径以容纳不同厚度的钻头。夹具固定元件各自包括L形螺栓和封闭螺栓的直段中的一个的门保护材料。

7. 发明申请

US20100090862A1 POINT-OF-USE ENERGY MONITORING AND MANAGEMENT 审中-公开
标题翻译：使用要点监测和管理
公开(公告)号：US20100090862A1
公开(公告)日：2010-04-15
申请号：US12554090
申请日：2009-09-04
申请人： Nicole M. Dubrow , Michael Block
发明人： Nicole M. Dubrow , Michael Block
IPC分类号： G08C19/16
CPC分类号： H04Q9/00 , H04Q2209/30 , H04Q2209/43 , H04Q2209/60
摘要： A system for monitoring and managing the energy consumption of designated devices or services obtains the point-of-use energy consumption of the designated devices or services and collects this consumption information in various formats as data. The collected data may be analyzed for peak load analysis and load shedding recommendations, among other analysis. The data may be displayed on a user interface to an energy consumer in various formats that permit the consumer to make decisions and take actions based on the displayed data or the analysis. The data may be displayed in real-time format so that the consumer may observe the instant energy consumption of a particular device. The consumer may also view a device's energy consumption to-date over a predetermined period of time. The consumer may also take an action through the system to reduce the consumer's overall energy consumption.
摘要翻译：用于监视和管理指定设备或服务的能量消耗的系统获得指定设备或服务的使用点能耗，并以数据形式收集各种格式的消费信息。收集的数据可以分析峰值负载分析和负载脱落建议，以及其他分析。数据可以以允许消费者基于显示的数据或分析作出决定并采取行动的各种格式的能量消费者的用户界面来显示。数据可以以实时格式显示，使得消费者可以观察特定设备的即时能量消耗。消费者还可以在预定时间段内查看设备的能量消耗。消费者也可以通过系统采取行动，以减少消费者的整体能源消耗。

8. 发明授权

US10047549B2 Latch 有权
公开(公告)号：US10047549B2
公开(公告)日：2018-08-14
申请号：US14116096
申请日：2012-05-11
申请人： Robert Grant , Michael Block
发明人： Robert Grant , Michael Block
IPC分类号： E05C1/06 , E05C1/14 , E05B41/00 , E05B59/00 , E05B63/14 , E05C1/00 , E05C1/04 , E05B5/00 , B64D11/04
摘要： A latch includes a first locking bolt, where a first extended position of the first locking bolt defines a first locked condition and a first retracted position defines a first unlocked condition. The latch also includes a second locking bolt, where a second extended position of the second locking bolt defines a second locked condition and a second retracted position defines a second unlocked condition. A biasing member operatively connects to the first locking bolt to bias the first locking bolt in the first extended position. A lever pivotally connects to the housing and operatively connects to the first locking bolt such that movement of the lever from a closed position to an opened position causes at least the first locking bolt to move from the first extended position to the first retracted position. A locking indicator is provided in associated with the second locking bolt.

9. 发明申请

US20050080106A1 Compounds effecting glucokinase 失效
标题翻译：影响葡萄糖激酶的化合物
公开(公告)号：US20050080106A1
公开(公告)日：2005-04-14
申请号：US10486496
申请日：2002-08-15
申请人： Scott Boyd , Peter Caulkett , Rodney Hargreaves , Suzanne Bowker , Roger James , Clifford Jones , Darren McKerrecher , Michael Block , Craig Johnstone
发明人： Scott Boyd , Peter Caulkett , Rodney Hargreaves , Suzanne Bowker , Roger James , Clifford Jones , Darren McKerrecher , Michael Block , Craig Johnstone
IPC分类号： A61K31/165 , A61K31/167 , A61K31/192 , A61K31/195 , A61K31/341 , A61K31/415 , A61K31/4155 , A61K31/42 , A61K31/425 , A61K31/426 , A61K31/427 , A61K31/428 , A61K31/433 , A61K31/44 , A61K31/4402 , A61K31/4436 , A61K31/4439 , A61K31/444 , A61K31/445 , A61K31/454 , A61K31/455 , A61K31/496 , A61K31/4965 , A61K31/497 , A61K31/50 , A61K31/501 , A61K31/505 , A61K31/506 , A61K31/5377 , A61P3/04 , A61P3/06 , A61P3/10 , A61P43/00 , C07D213/75 , C07D213/76 , C07D213/82 , C07D213/85 , C07D231/40 , C07D233/48 , C07D237/20 , C07D237/24 , C07D239/42 , C07D239/47 , C07D241/20 , C07D241/26 , C07D241/28 , C07D261/14 , C07D277/20 , C07D277/46 , C07D277/54 , C07D277/56 , C07D277/58 , C07D277/82 , C07D285/12 , C07D285/135 , C07D307/66 , C07D307/68 , C07D401/04 , C07D403/04 , C07D405/12 , C07D409/12 , C07D409/14 , C07D413/04 , C07D413/12 , C07D413/14 , C07D417/04 , C07D417/12 , C07D417/14
CPC分类号： C07D213/75 , A61K31/165 , A61K31/195 , A61K31/425 , A61K31/445 , C07D213/82 , C07D213/85 , C07D231/40 , C07D233/48 , C07D237/20 , C07D237/24 , C07D239/42 , C07D241/20 , C07D241/26 , C07D261/14 , C07D277/46 , C07D277/56 , C07D277/82 , C07D285/135 , C07D307/66 , C07D401/04 , C07D403/04 , C07D405/12 , C07D409/12 , C07D409/14 , C07D413/04 , C07D413/12 , C07D413/14 , C07D417/04 , C07D417/12 , C07D417/14
摘要： The invention relates to the use of a compound of Formula (I) or a salt, solvate or prodrug thereof, wherein R1, R2, R3, n and m are as described in the specification, in the preparation of a medicament for the treatment or prevention of a disease condition mediated through glucokinase (GLK), such as type 2 diabetes. The invention also relates to a novel group of compounds of Formula (I) and to methods for preparing compounds of Formula (I).
摘要翻译：本发明涉及式（I）化合物或其盐，溶剂合物或前体药物的用途，其中R 1，R 2，R 3，n和m如说明书中所述，在制备用于治疗或预防通过葡萄糖激酶（GLK）介导的疾病状况的药物，例如2型糖尿病。本发明还涉及一组新的式（I）化合物和制备式（I）化合物的方法。

10. 发明公开

US20230373014A1 CORING TOOL 审中-公开
公开(公告)号：US20230373014A1
公开(公告)日：2023-11-23
申请号：US18315588
申请日：2023-05-11
申请人： Michael Block
发明人： Michael Block
IPC分类号： B23B47/28
CPC分类号： B23B47/28 , B23B2247/06
摘要： A coring tool for coring doors is provided. The coring tool may include a tool body having a first end and an opposing second end and a clamp member coupled to the tool body adjacent the second end. The tool body and the clamp member are moveable toward and away from each other in response to operation of a clamp actuator. The coring tool may also include a head having guide bushings for inserting a bit through the guide bushings for coring a door. The head may be coupled adjacent the first end of the tool body and the head may be movable toward and away from the tool body to align the guide bushing with the door to be cored.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式