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1. 发明授权

US07968348B2 Environmental sampling and testing method 有权
标题翻译：环境取样和检测方法
公开(公告)号：US07968348B2
公开(公告)日：2011-06-28
申请号：US12274923
申请日：2008-11-20
申请人： Brendi M. Cumberland , Maha El-Sayed , Alan J. Fujii , Scott D Manske , Elias A. Shaheen
发明人： Brendi M. Cumberland , Maha El-Sayed , Alan J. Fujii , Scott D Manske , Elias A. Shaheen
IPC分类号： G01N33/53
CPC分类号： G01N33/558 , G01N31/22 , G01N2001/028 , Y10S435/97 , Y10S436/807 , Y10S977/70 , Y10S977/773 , Y10S977/788 , Y10S977/918
摘要： Provided is sampling and testing device for the detection of specific molds, allergens, viruses, bacteria, fungi, and other protein containing substances. Embodiments of the device include a sampling member slideably engaged with a base that contains a lateral flow strip adapted to detect specific analytes of interest. The sampling member defines a solvent reservoir that stores an elution solvent in a fluid-tight manner before the device is used to sample and test environmental surfaces. During slideable withdrawal of the sampling member from the base, the elution solvent stored in the reservoir is automatically released to a wick assembly of the sampling member. The wick assembly includes a wick adapted to receive, distribute, and retain the elution solvent. After a user samples an environmental surface for an analyte of interest with the elution solvent wetted wick, the sampling member is returned to the base where the wick contacts the lateral flow strip contained in the base. The wick transfers at least a portion of analyte and the elution solvent to the lateral flow strip for the colorimetric detection of specific allergens, viruses, bacteria, and other protein containing substances in the sample. The colorimetric results of the test are displayed through a window in the base.
摘要翻译：提供了用于检测特定霉菌，过敏原，病毒，细菌，真菌和其他含蛋白质物质的取样和检测装置。该装置的实施例包括可滑动地与基座接合的采样构件，其包含适于检测感兴趣的特定分析物的侧向流动条。采样构件在使用该装置对环境表面进行采样和测试之前，限定了以流体密封的方式存储洗脱溶剂的溶剂储存器。在将取样构件从基底滑动取出时，储存在储存器中的洗脱溶剂自动释放到取样构件的芯组件上。芯组件包括适于接收，分配和保留洗脱溶剂的芯。在用户使用洗脱溶剂润湿的吸管对用于所关注的分析物的环境表面进行采样之后，采样部件返回到基座，其中芯接触包含在基部中的侧向流动条。芯芯将至少一部分分析物和洗脱溶剂转移到侧流条上，以便比色检测样品中的特定过敏原，病毒，细菌和其他含蛋白质的物质。测试的比色结果通过基座中的窗口显示。

2. 发明申请

US20090075250A1 Environmental Sampling and Testing Method 有权
标题翻译：环境取样和测试方法
公开(公告)号：US20090075250A1
公开(公告)日：2009-03-19
申请号：US12274923
申请日：2008-11-20
申请人： Brendi M. Cumberland , Maha El-Sayed , Alan J. Fujii , Scott D. Manske , Elias A. Shaheen
发明人： Brendi M. Cumberland , Maha El-Sayed , Alan J. Fujii , Scott D. Manske , Elias A. Shaheen
IPC分类号： C12Q1/70 , C12Q1/04 , G01N33/68 , G01N33/53
CPC分类号： G01N33/558 , G01N31/22 , G01N2001/028 , Y10S435/97 , Y10S436/807 , Y10S977/70 , Y10S977/773 , Y10S977/788 , Y10S977/918
摘要： Provided is sampling and testing device for the detection of specific molds, allergens, viruses, bacteria, fungi, and other protein containing substances. Embodiments of the device include a sampling member slideably engaged with a base that contains a lateral flow strip adapted to detect specific analytes of interest. The sampling member defines a solvent reservoir that stores an elution solvent in a fluid-tight manner before the device is used to sample and test environmental surfaces. During slideable withdrawal of the sampling member from the base, the elution solvent stored in the reservoir is automatically released to a wick assembly of the sampling member. The wick assembly includes a wick adapted to receive, distribute, and retain the elution solvent. After a user samples an environmental surface for an analyte of interest with the elution solvent wetted wick, the sampling member is returned to the base where the wick contacts the lateral flow strip contained in the base. The wick transfers at least a portion of analyte and the elution solvent to the lateral flow strip for the calorimetric detection of specific allergens, viruses, bacteria, and other protein containing substances in the sample. The calorimetric results of the test are displayed through a window in the base.
摘要翻译：提供了用于检测特定霉菌，过敏原，病毒，细菌，真菌和其他含蛋白质物质的取样和检测装置。该装置的实施例包括可滑动地与基座接合的采样构件，其包含适于检测感兴趣的特定分析物的侧向流动条。采样构件在使用该装置对环境表面进行采样和测试之前，限定了以流体密封的方式存储洗脱溶剂的溶剂储存器。在将取样构件从基底滑动取出时，储存在储存器中的洗脱溶剂自动释放到取样构件的芯组件上。芯组件包括适于接收，分配和保留洗脱溶剂的芯。在用户使用洗脱溶剂润湿的吸管对用于所关注的分析物的环境表面进行采样之后，采样部件返回到基座，其中芯接触包含在基部中的侧向流动条。芯芯将至少一部分分析物和洗脱溶剂转移到侧流条上，以对样品中的特定过敏原，病毒，细菌和其他含蛋白质的物质进行量热检测。测试的量热结果通过基座中的窗口显示。

3. 发明授权

US07473563B2 Environmental sampling and testing device 有权
标题翻译：环境抽样检测装置
公开(公告)号：US07473563B2
公开(公告)日：2009-01-06
申请号：US11397522
申请日：2006-04-03
申请人： Brendi M. Cumberland , Maha El-Sayed , Alan J. Fujii , Scott D. Manske , Elias A. Shaheen
发明人： Brendi M. Cumberland , Maha El-Sayed , Alan J. Fujii , Scott D. Manske , Elias A. Shaheen
IPC分类号： G01N33/53
CPC分类号： G01N33/558 , G01N31/22 , G01N2001/028 , Y10S435/97 , Y10S436/807 , Y10S977/70 , Y10S977/773 , Y10S977/788 , Y10S977/918
摘要： Provided is sampling and testing device for the detection of specific molds, allergens, viruses, bacteria, fungi, and other protein containing substances. Embodiments of the device include a sampling member slideably engaged with a base that contains a lateral flow strip adapted to detect specific analytes of interest. The sampling member defines a solvent reservoir that stores an elution solvent in a fluid-tight manner before the device is used to sample and test environmental surfaces. During slideable withdrawal of the sampling member from the base, the elution solvent stored in the reservoir is automatically released to a wick assembly of the sampling member. The wick assembly includes a wick adapted to receive, distribute, and retain the elution solvent. After a user samples an environmental surface for an analyte of interest with the elution solvent wetted wick, the sampling member is returned to the base where the wick contacts the lateral flow strip contained in the base. The wick transfers at least a portion of analyte and the elution solvent to the lateral flow strip for the calorimetric detection of specific allergens, viruses, bacteria, and other protein containing substances in the sample. The colorimetric results of the test are displayed through a window in the base.
摘要翻译：提供了用于检测特定霉菌，过敏原，病毒，细菌，真菌和其他含蛋白质物质的取样和检测装置。该装置的实施例包括可滑动地与基座接合的采样构件，其包含适于检测感兴趣的特定分析物的侧向流动条。采样构件在使用该装置对环境表面进行采样和测试之前，限定了以流体密封的方式存储洗脱溶剂的溶剂储存器。在将取样构件从基底滑动取出时，储存在储存器中的洗脱溶剂自动释放到取样构件的芯组件上。芯组件包括适于接收，分配和保留洗脱溶剂的芯。在用户使用洗脱溶剂润湿的吸管对用于所关注的分析物的环境表面进行采样之后，采样部件返回到基座，其中芯接触包含在基部中的侧向流动条。芯芯将至少一部分分析物和洗脱溶剂转移到侧流条上，以对样品中的特定过敏原，病毒，细菌和其他含蛋白质的物质进行量热检测。测试的比色结果通过基座中的窗口显示。

4. 发明申请

US20080003144A1 SAMPLING DEVICE 审中-公开
标题翻译：采样设备
公开(公告)号：US20080003144A1
公开(公告)日：2008-01-03
申请号：US11427469
申请日：2006-06-29
申请人： Brendi M. Cumberland , Alan J. Fujii , Scott D. Manske , Elias A. Shaheen
发明人： Brendi M. Cumberland , Alan J. Fujii , Scott D. Manske , Elias A. Shaheen
IPC分类号： B01L3/00
CPC分类号： B01L3/5029 , B01L2200/16 , B01L2300/047 , B01L2300/0867 , B01L2400/0406 , B01L2400/0694 , G01N1/10
摘要： Provided is sampling device and method for the detection of an analyte of interest on an environmental surface. The sampling device includes a first reservoir adapted to contain a first liquid, a second reservoir adapted to contain a second liquid, a swab holder coupled to the first reservoir and the second reservoir, a swab disposed within the swab holder, and an activation member coupled to the first and second reservoirs opposite the swab holder. After the swab is used to collect a sample from an environmental surface, and upon application of an activation force on the activation member, the first and second reservoirs are placed in fluid communication with the swab holder and the first and second liquids flow into the swab holder to contact the swab. The swab develops an indicator color if the sample of the environmental surface contained the analyte of interest.
摘要翻译：提供了用于在环境表面上检测感兴趣的分析物的取样装置和方法。采样装置包括适于容纳第一液体的第一储存器，适于容纳第二液体的第二储存器，耦合到第一储存器和第二储存器的拭子保持器，布置在拭子保持器内的拭子和联接到与棉签持有人对面的第一和第二个水库。在将拭子用于从环境表面收集样品之后，并且在致动构件上施加激活力时，将第一和第二储存器放置成与拭子保持器流体连通，并且第一和第二液体流入拭子持有人联系拭子。如果环境表面的样品含有感兴趣的分析物，则棉签会产生指示剂颜色。

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