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1. 发明申请

US20110028813A1 Systems And Methods For Estimating Values Of A Continuous Wavelet Transform 有权
标题翻译：用于估计连续小波变换值的系统和方法
公开(公告)号：US20110028813A1
公开(公告)日：2011-02-03
申请号：US12512132
申请日：2009-07-30
申请人： James Nicholas Watson , Paul Stanley Addison , Braddon M. Van Slyke
发明人： James Nicholas Watson , Paul Stanley Addison , Braddon M. Van Slyke
IPC分类号： A61B5/1455
CPC分类号： A61B5/726 , A61B5/0205 , A61B5/1455 , A61B5/14551 , A61B5/7203 , G06F17/148 , G06K9/00523
摘要： According to embodiments, techniques for estimating scalogram energy values in a wedge region of a scalogram are disclosed. A pulse oximetry system including a sensor or probe may be used to receive a photoplethysmograph (PPG) signal from a patient or subject. A scalogram, corresponding to the obtained PPG signal, may be determined. In an arrangement, energy values in the wedge region of the scalogram may be estimated by calculating a set of estimation locations in the wedge region and estimating scalogram energy values at each location. In an arrangement, scalogram energy values may be estimated based on an estimation scheme and by combining scalogram values in a vicinity region. In an arrangement, the vicinity region may include energy values in a resolved region of the scalogram and previously estimated energy values in the wedge region of the scalogram. In an arrangement, one or more signal parameters may be determined based on the resolved and estimated values of the scalogram.
摘要翻译：根据实施例，公开了用于估计缩水图的楔形区域中的标尺能量值的技术。可以使用包括传感器或探针的脉搏血氧饱和度测定系统来接收来自患者或受试者的光谱体积描记器（PPG）信号。可以确定对应于所获得的PPG信号的标尺。在一种布置中，可以通过计算楔形区域中的一组估计位置并估计每个位置处的标尺能量值，来估计缩小图楔形区域中的能量值。在一种布置中，可以基于估计方案并且通过组合邻近区域中的标尺值来估计标尺能量值。在一种布置中，附近区域可以包括在缩放图的解析区域中的能量值和在缩放图形的楔形区域中的先前估计的能量值。在一种布置中，可以基于缩放图的分辨和估计值来确定一个或多个信号参数。

2. 发明授权

US08478376B2 Systems and methods for determining physiological information using selective transform data 失效
标题翻译：使用选择性变换数据确定生理信息的系统和方法
公开(公告)号：US08478376B2
公开(公告)日：2013-07-02
申请号：US12512143
申请日：2009-07-30
申请人： Braddon M. Van Slyke , Paul Stanley Addison , James Nicholas Watson , Scott McGonigle
发明人： Braddon M. Van Slyke , Paul Stanley Addison , James Nicholas Watson , Scott McGonigle
IPC分类号： A61B5/1455
CPC分类号： G06K9/00516 , A61B5/02416 , A61B5/14551 , A61B5/7207 , A61B5/726
摘要： According to embodiments, a pulse band region is identified in a wavelet scalogram of a physiological signal (e.g., a plethysmograph or photoplethysmograph signal). Components of the scalogram at scales larger than the identified pulse band region are then used to determine a baseline signal in wavelet space. The baseline signal may then be used to normalize the physiological signal. Physiological information may be determined from the normalized signal. For example, oxygen saturation may be determined using a ratio of ratios or any other suitable technique.
摘要翻译：根据实施例，在生理信号（例如，体积描记器或光电体积描记信号）的小波图示中识别脉冲带区域。然后使用尺度大于识别的脉冲带区域的标尺的分量来确定小波空间中的基线信号。然后可以使用基线信号来标准化生理信号。生理信息可以从归一化信号确定。例如，氧饱和度可以使用比率或任何其它合适的技术来确定。

3. 发明授权

US08346333B2 Systems and methods for estimating values of a continuous wavelet transform 有权
公开(公告)号：US08346333B2
公开(公告)日：2013-01-01
申请号：US12512132
申请日：2009-07-30
申请人： James Nicholas Watson , Paul Stanley Addison , Braddon M. Van Slyke
发明人： James Nicholas Watson , Paul Stanley Addison , Braddon M. Van Slyke
IPC分类号： A61B5/1455 , A61B5/00 , G01N33/48
CPC分类号： A61B5/726 , A61B5/0205 , A61B5/1455 , A61B5/14551 , A61B5/7203 , G06F17/148 , G06K9/00523
摘要： According to embodiments, techniques for estimating scalogram energy values in a wedge region of a scalogram are disclosed. A pulse oximetry system including a sensor or probe may be used to receive a photoplethysmograph (PPG) signal from a patient or subject. A scalogram, corresponding to the obtained PPG signal, may be determined. In an arrangement, energy values in the wedge region of the scalogram may be estimated by calculating a set of estimation locations in the wedge region and estimating scalogram energy values at each location. In an arrangement, scalogram energy values may be estimated based on an estimation scheme and by combining scalogram values in a vicinity region. In an arrangement, the vicinity region may include energy values in a resolved region of the scalogram and previously estimated energy values in the wedge region of the scalogram. In an arrangement, one or more signal parameters may be determined based on the resolved and estimated values of the scalogram.

4. 发明申请

US20110077484A1 Systems And Methods For Identifying Non-Corrupted Signal Segments For Use In Determining Physiological Parameters 审中-公开
标题翻译：识别用于确定生理参数的无损信号段的系统和方法
公开(公告)号：US20110077484A1
公开(公告)日：2011-03-31
申请号：US12570388
申请日：2009-09-30
申请人： Braddon M. Van Slyke , Paul Stanley Addison , Scott McGonigle , James Nicholas Watson
发明人： Braddon M. Van Slyke , Paul Stanley Addison , Scott McGonigle , James Nicholas Watson
IPC分类号： A61B5/1455 , G06N3/02 , G06N3/08
CPC分类号： A61B5/02416 , A61B5/7203 , A61B5/7207 , A61B5/7221 , A61B5/7225 , A61B5/726 , A61B5/7264 , A61B5/7267
摘要： According to embodiments, non-corrupted signal segments are detected by a data modeling processor implementing an artificial neural network. The neural network may be trained to detect artifact in the signal (e.g., a PPG signal or some wavelet representation of a PPG signal) and gate valid signal segments for use in determining physiological parameters, such as, for example, pulse rate, oxygen saturation, pulse rate, respiration rate, and respiratory effort. When an artifact is detected, previously received known-good signal segments may be buffered and replace the signal segment or segments containing artifact. A regression analysis may also be performed in order to extrapolate new data from previously received known-good signal segments. In this way, more accurate and reliable physiological parameters may be determined.
摘要翻译：根据实施例，未损坏的信号段由实现人造神经网络的数据建模处理器检测。可以训练神经网络以检测信号中的伪像（例如，PPG信号或PPG信号的一些小波表示）和用于确定生理参数的门有效信号段，例如脉率，氧饱和度，脉率，呼吸频率和呼吸力。当检测到伪像时，先前接收的已知良好信号段可以被缓冲并且替换包含伪像的信号段或段。还可以进行回归分析以从先前接收的已知良好信号段推断新数据。以这种方式，可以确定更精确和可靠的生理参数。

5. 发明申请

US20100298676A1 Estimating Transform Values Using Signal Estimates 有权
标题翻译：使用信号估计估计变换值
公开(公告)号：US20100298676A1
公开(公告)日：2010-11-25
申请号：US12469491
申请日：2009-05-20
申请人： Paul Stanley Addison , James Nicholas Watson , Braddon M. Van Slyke
发明人： Paul Stanley Addison , James Nicholas Watson , Braddon M. Van Slyke
IPC分类号： A61B5/1455
CPC分类号： A61B5/14551 , A61B5/726 , A61B2562/0233 , A61B2562/046
摘要： According to embodiments, estimated values for a signal transform may be generated using estimated values for the signal. Signal parameters may then be determined based on the estimated signal transform. A first portion of a signal may be obtained. A second portion of the signal may be estimated. The second portion of the signal may correspond to a portion of the that is unknown, that is not yet available and/or that is obscured by noise and/or artifacts. A transform (e.g., a continuous wavelet transform) of both of the signal portions may be performed. One or more parameters corresponding to the signal may then be determined from transformed signal.
摘要翻译：根据实施例，可以使用信号的估计值来生成信号变换的估计值。然后可以基于估计的信号变换来确定信号参数。可以获得信号的第一部分。可以估计信号的第二部分。信号的第二部分可以对应于未知的部分，即尚不可用和/或被噪声和/或伪影遮蔽的部分。可以执行两个信号部分的变换（例如，连续小波变换）。然后可以从变换的信号确定对应于信号的一个或多个参数。

6. 发明授权

US08594759B2 Systems and methods for resolving the continuous wavelet transform of a signal 有权
标题翻译：用于解决信号的连续小波变换的系统和方法
公开(公告)号：US08594759B2
公开(公告)日：2013-11-26
申请号：US12512113
申请日：2009-07-30
申请人： Braddon M. Van Slyke , Paul Stanley Addison , James Nicholas Watson
发明人： Braddon M. Van Slyke , Paul Stanley Addison , James Nicholas Watson
IPC分类号： A61B5/00 , G01N33/48 , G01N33/50 , G06F17/14
CPC分类号： G06F17/148 , A61B5/1455 , A61B5/7203 , A61B5/7225 , A61B5/726 , G06K9/00516
摘要： According to an embodiment, techniques for estimating scalogram energy values in a wedge region of a scalogram are disclosed. A pulse oximetry system including a sensor or probe may be used to receive a photoplethysmograph (PPG) signal from a patient or subject. A scalogram, corresponding to the obtained PPG signal, may be determined. In an approach, energy values in the wedge region of the scalogram may be estimated by performing convolution-based or convolution-like operations on the obtained PPG signal, or a transformed version thereof, and the scalogram may be updated according to the estimated values. In an approach, a deskewing technique may be used to align data prior to adding the data to the scalogram. In an approach, one or more signal parameters may be determined based on the resolved and estimated values of the scalogram.
摘要翻译：根据一个实施例，公开了一种用于在缩水图的楔形区域中估计缩放能量值的技术。可以使用包括传感器或探针的脉搏血氧饱和度测定系统来接收来自患者或受试者的光谱体积描记器（PPG）信号。可以确定对应于所获得的PPG信号的标尺。在一种方法中，可以通过对所获得的PPG信号或其变换版本执行基于卷积或卷积的操作来估计缩放图楔形区域中的能量值，并且可以根据估计值更新缩放图。在一种方法中，可以使用偏斜技术在将数据添加到缩放图之前对准数据。在一种方法中，一个或多个信号参数可以基于缩放图的分辨和估计值来确定。

7. 发明授权

US08364225B2 Estimating transform values using signal estimates 有权
标题翻译：使用信号估计估算变换值
公开(公告)号：US08364225B2
公开(公告)日：2013-01-29
申请号：US12469491
申请日：2009-05-20
申请人： Paul Stanley Addison , James Nicholas Watson , Braddon M. Van Slyke
发明人： Paul Stanley Addison , James Nicholas Watson , Braddon M. Van Slyke
IPC分类号： A61B5/00 , A61B5/02 , A61B5/08 , G01N33/48 , G01N33/50
CPC分类号： A61B5/14551 , A61B5/726 , A61B2562/0233 , A61B2562/046
摘要： According to embodiments, estimated values for a signal transform may be generated using estimated values for the signal. Signal parameters may then be determined based on the estimated signal transform. A first portion of a signal may be obtained. A second portion of the signal may be estimated. The second portion of the signal may correspond to a portion of the that is unknown, that is not yet available and/or that is obscured by noise and/or artifacts. A transform (e.g., a continuous wavelet transform) of both of the signal portions may be performed. One or more parameters corresponding to the signal may then be determined from transformed signal.
摘要翻译：根据实施例，可以使用信号的估计值来生成信号变换的估计值。然后可以基于估计的信号变换来确定信号参数。可以获得信号的第一部分。可以估计信号的第二部分。信号的第二部分可以对应于未知的部分，即尚不可用和/或被噪声和/或伪影遮蔽的部分。可以执行两个信号部分的变换（例如，连续小波变换）。然后可以从变换的信号确定对应于信号的一个或多个参数。

8. 发明申请

US20110028810A1 Systems And Methods For Resolving The Continuous Wavelet Transform Of A Signal 有权
标题翻译：用于解决信号的连续小波变换的系统和方法
公开(公告)号：US20110028810A1
公开(公告)日：2011-02-03
申请号：US12512113
申请日：2009-07-30
申请人： Braddon M. Van Slyke , Paul Stanley Addison , James Nicholas Watson
发明人： Braddon M. Van Slyke , Paul Stanley Addison , James Nicholas Watson
IPC分类号： A61B5/145
CPC分类号： G06F17/148 , A61B5/1455 , A61B5/7203 , A61B5/7225 , A61B5/726 , G06K9/00516
摘要： According to an embodiment, techniques for estimating scalogram energy values in a wedge region of a scalogram are disclosed. A pulse oximetry system including a sensor or probe may be used to receive a photoplethysmograph (PPG) signal from a patient or subject. A scalogram, corresponding to the obtained PPG signal, may be determined. In an approach, energy values in the wedge region of the scalogram may be estimated by performing convolution-based or convolution-like operations on the obtained PPG signal, or a transformed version thereof, and the scalogram may be updated according to the estimated values. In an approach, a deskewing technique may be used to align data prior to adding the data to the scalogram. In an approach, one or more signal parameters may be determined based on the resolved and estimated values of the scalogram.
摘要翻译：根据一个实施例，公开了一种用于在缩水图的楔形区域中估计缩放能量值的技术。可以使用包括传感器或探针的脉搏血氧饱和度测定系统来接收来自患者或受试者的光谱体积描记器（PPG）信号。可以确定对应于所获得的PPG信号的标尺。在一种方法中，可以通过对所获得的PPG信号或其变换版本执行基于卷积或卷积的操作来估计缩放图楔形区域中的能量值，并且可以根据估计值更新缩放图。在一种方法中，可以使用偏斜技术在将数据添加到缩放图之前对准数据。在一种方法中，一个或多个信号参数可以基于缩放图的分辨和估计值来确定。

9. 发明申请

US20110026784A1 Systems And Methods For Determining Physiological Information Using Selective Transform Data 失效
标题翻译：使用选择性变换数据确定生理信息的系统和方法
公开(公告)号：US20110026784A1
公开(公告)日：2011-02-03
申请号：US12512143
申请日：2009-07-30
申请人： Braddon M. Van Slyke , Paul Stanley Addison , James Nicholas Watson , Scott McGonigle
发明人： Braddon M. Van Slyke , Paul Stanley Addison , James Nicholas Watson , Scott McGonigle
IPC分类号： G06K9/00
CPC分类号： G06K9/00516 , A61B5/02416 , A61B5/14551 , A61B5/7207 , A61B5/726
摘要： According to embodiments, a pulse band region is identified in a wavelet scalogram of a physiological signal (e.g., a plethysmograph or photoplethysmograph signal). Components of the scalogram at scales larger than the identified pulse band region are then used to determine a baseline signal in wavelet space. The baseline signal may then be used to normalize the physiological signal. Physiological information may be determined from the normalized signal. For example, oxygen saturation may be determined using a ratio of ratios or any other suitable technique.
摘要翻译：根据实施例，在生理信号（例如，体积描记器或光电体积描记信号）的小波图示中识别脉冲带区域。然后使用尺度大于识别的脉冲带区域的标尺的分量来确定小波空间中的基线信号。然后可以使用基线信号来标准化生理信号。生理信息可以从归一化信号确定。例如，氧饱和度可以使用比率或任何其它合适的技术来确定。

10. 发明授权

US09357937B2 System and method for determining stroke volume of an individual 有权
标题翻译：用于确定个体的搏动量的系统和方法
公开(公告)号：US09357937B2
公开(公告)日：2016-06-07
申请号：US13605626
申请日：2012-09-06
申请人： James Nicholas Watson , Paul Stanley Addison
发明人： James Nicholas Watson , Paul Stanley Addison
IPC分类号： A61B5/0265 , A61B5/0285 , A61B5/029 , A61B5/0295
CPC分类号： A61B5/0265 , A61B5/0285 , A61B5/029 , A61B5/0295
摘要： A system for determining stroke volume of an individual. The system includes a skew-determining module that is configured to calculate a first derivative of photoplethysmogram (PPG) signals of the individual. The first derivative forms a derivative waveform. The skew-determining module is configured to determine a skew metric of the first derivative, wherein the skew metric is indicative of a morphology of at least one pulse wave detected from blood flow of the individual in the derivative waveform. The system also includes an analysis module that is configured to determine a stroke volume of the individual. The stroke volume is a function of the skew metric of the first derivative.
摘要翻译：一种用于确定个体的搏动量的系统。该系统包括偏差确定模块，其被配置为计算个体的光谱体积描记图（PPG）信号的一阶导数。一阶导数形成导数波形。偏移确定模块被配置为确定一阶导数的偏斜量度，其中偏斜度量指示从导数波形中个体的血流检测到的至少一个脉搏波的形态。该系统还包括分析模块，该分析模块被配置为确定个人的冲程体积。行程体积是一阶导数的偏差度量的函数。

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