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1. 发明申请

WO2008042890A1 COMMON BOND, DOUBLE-BALLOON CATHETER 审中-公开
标题翻译：通用粘合剂，双壁气体导管
公开(公告)号：WO2008042890A1
公开(公告)日：2008-04-10
申请号：PCT/US2007/080167
申请日：2007-10-02
申请人： BOSTON SCIENTIFIC SCIMED, INC. , LAFONTAINE, Daniel M. , HENDRICKSON, Gary L.
发明人： LAFONTAINE, Daniel M. , HENDRICKSON, Gary L.
IPC分类号： A61M25/00 , A61M25/10 , A61B18/02
CPC分类号： A61M25/1011 , A61B2018/0022 , A61B2018/00577 , A61B2018/0212 , A61B2018/0262 , A61M25/1034 , A61M2025/1013 , A61M2025/1079
摘要： A method of manufacturing a catheter can include assembling an inner balloon within a separate outer balloon. The inner and outer balloons can each be open on opposing longitudinal ends and have a central radially expandable portion, and proximal and distal reduced diameter portions on opposite longitudinal end portions of the balloon. The method can further include bonding a portion of an inner surface of the outer balloon proximal reduced diameter portion to a portion of an outer surface of the inner balloon proximal reduced diameter portion and bonding a distal end portion of an elongate catheter shaft to a proximal portion of the bonded inner and outer balloons.
摘要翻译：制造导管的方法可以包括将内气囊组装在单独的外气囊中。内部和外部气囊可以在相对的纵向端部上敞开，并且具有中心径向可膨胀部分，并且在气囊的相对的纵向端部上具有近端和远端缩径部分。该方法还可以包括将外球囊近端缩小直径部分的内表面的一部分粘合到内球囊近直径部分的外表面的一部分，并将细长导管轴的远端部分接合到近端部分的粘合内外气球。

2. 发明申请

WO2008034005A2 CARDIAC STIMULATION USING LEADLESS ELECTRODE ASSEMBLIES 审中-公开
标题翻译：使用无电极电极组件刺激心脏
公开(公告)号：WO2008034005A2
公开(公告)日：2008-03-20
申请号：PCT/US2007/078405
申请日：2007-09-13
申请人： BOSTON SCIENTIFIC SCIMED, INC. , HASTINGS, Roger N. , LAFONTAINE, Daniel M. , PIKUS, Michael J. , WILLARD, Martin R.
发明人： HASTINGS, Roger N. , LAFONTAINE, Daniel M. , PIKUS, Michael J. , WILLARD, Martin R.
IPC分类号： A61N1/00
CPC分类号： A61N1/059 , A61N1/365 , A61N1/372 , A61N1/37205 , A61N1/37288 , A61N1/375 , A61N1/3756
摘要： An implantable cardiac tissue excitation system includes an implantable pacing controller unit with a pulse generation circuit. The system also includes a lead with a lead body extending between a proximal lead end attachable to the pacing controller unit and a distal lead end configured to be implanted within a heart. A lead conductor extends within the lead body. The system also includes a transmitter assembly located near the distal lead end that is electrically connected to the pulse generation circuit through the lead conductor to wirelessly transmit pacing control information and pacing energy. The system also includes a leadless electrode assembly configured to be implanted within the heart that includes a receiver to receive the wireless transmission, a charge storage unit to store the charge energy, and an electrical stimulation circuit to deliver an electrical stimulus to cardiac tissue using the pacing control information and the charge energy.
摘要翻译：可植入心脏组织激励系统包括具有脉冲发生电路的可植入起搏控制器单元。该系统还包括引线，引线主体在可附接到起搏控制器单元的近端引线端和配置成植入心脏内的远端引线端之间延伸。引线导体在引线体内延伸。该系统还包括位于远端引线端附近的发射器组件，该发射器组件通过引线导体电连接到脉冲发生电路以无线地发射起搏控制信息和起搏能量。该系统还包括被配置为植入心脏内的无引线电极组件，该无引线电极组件包括用于接收无线传输的接收器，用于存储电荷能量的电荷存储单元以及用于使用电信号向心脏组织递送电刺激的电刺激电路起搏控制信息和充电能量。

3. 发明申请

WO2007067253A1 CARDIAC STIMULATION SYSTEM 审中-公开
标题翻译：心脏刺激系统
公开(公告)号：WO2007067253A1
公开(公告)日：2007-06-14
申请号：PCT/US2006/040291
申请日：2006-10-13
申请人： BOSTON SCIENTIFIC SCIMED, INC. , DRASLER, William J. , PIKUS, Michael J. , HASTINGS, Roger N. , SMITH, Scott R. , WILLARD, Martin R. , LAFONTAINE, Daniel M. , SAHOLT, Douglas R. , KVEEN, Graig L.
发明人： DRASLER, William J. , PIKUS, Michael J. , HASTINGS, Roger N. , SMITH, Scott R. , WILLARD, Martin R. , LAFONTAINE, Daniel M. , SAHOLT, Douglas R. , KVEEN, Graig L.
IPC分类号： A61N1/00 , A61B5/00
CPC分类号： A61N1/059 , A61B5/0031 , A61B5/042 , A61B5/6848 , A61B5/6882 , A61N1/0573 , A61N1/3684 , A61N1/37205 , A61N1/3756
摘要： Some embodiments of pacing systems employ wireless electrode assemblies to provide pacing therapy. The wireless electrode assemblies may wirelessly receive energy via an inductive coupling so as to provide electrical stimulation to the surrounding heart tissue. In certain embodiments, the wireless electrode assembly may include one or more biased tines that shift from a first position to a second position to secure the wireless electrode assembly into the inner wall of the heart chamber.
摘要翻译：起搏系统的一些实施例采用无线电极组件来提供起搏治疗。无线电极组件可以通过电感耦合无线地接收能量，以便向周围的心脏组织提供电刺激。在某些实施例中，无线电极组件可以包括从第一位置移动到第二位置的一个或多个偏置尖齿，以将无线电极组件固定到心室的内壁。

4. 发明申请

WO2009046073A1 CONNECTIVE TISSUE CLOSURE DEVICE AND METHOD 审中-公开
标题翻译：连接组织封闭装置及方法
公开(公告)号：WO2009046073A1
公开(公告)日：2009-04-09
申请号：PCT/US2008/078405
申请日：2008-10-01
申请人： BOSTON SCIENTIFIC SCIMED, INC. , LAFONTAINE, Daniel M.
发明人： LAFONTAINE, Daniel M.
IPC分类号： A61B17/00
CPC分类号： A61B17/0057 , A61B17/0401 , A61B17/0487 , A61B2017/00004 , A61B2017/00663 , A61B2017/0409 , A61B2017/0448 , A61B2017/045 , A61B2017/0488
摘要： A device (20) for closing wounds such as openings in blood vessels as well as a method of doing so are disclosed. The device employs a fabric wrapped (24) around an expandable frame (22) both of which are inserted into a blood vessel through an introducer sheath (26). Once inserted, the expandable frame expands thereby expanding the fabric therewith. The fabric is made from a bioabsorable material and includes a plurality of microhooks (62) extending therefrom. One suitable material is polylactic acid fiber. Upon retraction of the device, the microhooks engage the adventitia surrounding the blood vessel causing the fabric to remain in position sealing the opening even after the expandable member is retracted and removed as well as the introducer sheath. As the fabric is made from a bioabsorable material, the device can remain in place even after hemostasis is reached and eventually dissolve within the body.
摘要翻译：公开了用于关闭诸如血管中的开口的伤口的装置（20）以及这样做的方法。该装置采用在可扩展框架（22）周围包裹（24）的织物，两者都通过引导器护套（26）插入血管。一旦插入，可膨胀框架膨胀，从而使织物膨胀。织物由生物可吸收材料制成并且包括从其延伸的多个微钩（62）。一种合适的材料是聚乳酸纤维。当装置缩回时，微钩与血管周围的外膜接合，导致即使在可扩张构件缩回和移除以及导引鞘之后，织物也保持在密封开口的位置。由于织物由生物可吸收材料制成，所以即使达到止血之后，该装置也可以保持在适当位置，并最终溶解在体内。

5. 发明申请

WO2006113496A2 VALVE APPARATUS, SYSTEM AND METHOD 审中-公开
标题翻译：阀门装置，系统和方法
公开(公告)号：WO2006113496A2
公开(公告)日：2006-10-26
申请号：PCT/US2006/014192
申请日：2006-04-17
申请人： BOSTON SCIENTIFIC SCIMED, INC. , LAFONTAINE, Daniel M.
发明人： LAFONTAINE, Daniel M.
IPC分类号： A61F2/24
CPC分类号： A61F2/2412 , A61F2/2418 , A61F2/2433 , A61F2/2436 , A61F2/2439 , A61F2220/0016 , A61F2220/005 , A61F2220/0058 , A61M25/1011
摘要： A cardiac valve with a first anchor frame and a cover on the first anchor frame for unidirectional flow of a liquid through the valve.
摘要翻译：一种心脏瓣膜，其具有第一锚固框架和第一锚固框架上的盖子，用于液体通过所述瓣膜的单向流动。

6. 发明申请

WO2006045074A2 LEADLESS CARDIAC STIMULATION SYSTEMS 审中-公开
标题翻译：无铅心脏刺激系统
公开(公告)号：WO2006045074A2
公开(公告)日：2006-04-27
申请号：PCT/US2005/037978
申请日：2005-10-19
申请人： BOSTON SCIENTIFIC SCIMED, INC. , HASTINGS, Roger N. , DRASSLER, William J. , LAFONTAINE, Daniel M. , SADASIVA, Anupama , SMITH, Scott R.
发明人： HASTINGS, Roger N. , DRASSLER, William J. , LAFONTAINE, Daniel M. , SADASIVA, Anupama , SMITH, Scott R.
IPC分类号： A61N1/05 , A61N1/378 , A61N1/372 , A61M31/00
CPC分类号： A61N1/3756 , A61N1/0587 , A61N1/059 , A61N1/08 , A61N1/3627 , A61N1/365 , A61N1/37205 , A61N1/37217 , A61N1/37223 , A61N1/37229 , A61N1/37241 , A61N1/37288 , A61N1/375 , A61N1/3787
摘要： Various configurations of systems that employ leadless electrodes to provide pacing therapy are provided. In one example, a system that provides multiple sites for pacing of myocardium of a heart includes wireless pacing electrodes that are implantable at sites proximate the myocardium using a percutaneous, transluminal, catheter delivery system. Each of the electrodes contains a source of electrical energy for pacing the myocardium and is adapted to receive electromagnetic energy from a source outside the myocardium. The system also includes a source adapted for placement outside the myocardium and that uses locally measured electrocardiograms to synchronize pacing of the heart by sending electromagnetic commands to the electrodes to pace the myocardium surrounding the electrodes. Also disclosed is various configurations of such systems, wireless electrode assemblies, and delivery catheters for delivering and implanting the electrode assemblies.
摘要翻译：提供了使用无引线电极来提供起搏治疗的各种构造的系统。在一个示例中，提供用于心脏心肌的多个部位的系统包括使用经皮，经腔，导管递送系统可植入位于心肌附近的位置的无线起搏电极。每个电极包含用于起搏心肌的电能源，并且适于从心肌外部的源接收电磁能。该系统还包括适于放置在心肌外部的源，并且使用局部测量的心电图来通过向电极发送电磁命令来同步心脏的起搏，以对电极周围的心肌进行加速。还公开了用于递送和植入电极组件的这种系统，无线电极组件和输送导管的各种配置。

7. 发明授权

EP1957148B1 CARDIAC STIMULATION SYSTEM 有权
标题翻译：心脏起搏系统
公开(公告)号：EP1957148B1
公开(公告)日：2011-02-23
申请号：EP06825988.6
申请日：2006-10-13
申请人： Boston Scientific Scimed, Inc.
发明人： DRASLER, William J. , PIKUS, Michael J. , HASTINGS, Roger N. , SMITH, Scott R. , WILLARD, Martin R. , LAFONTAINE, Daniel M. , SAHOLT, Douglas R. , KVEEN, Graig L.
IPC分类号： A61N1/05 , A61N1/372
CPC分类号： A61N1/059 , A61B5/0031 , A61B5/042 , A61B5/6848 , A61B5/6882 , A61N1/0573 , A61N1/3684 , A61N1/37205 , A61N1/3756
摘要： Some embodiments of pacing systems employ wireless electrode assemblies to provide pacing therapy. The wireless electrode assemblies may wirelessly receive energy via an inductive coupling so as to provide electrical stimulation to the surrounding heart tissue. In certain embodiments, the wireless electrode assembly may be pivotable so that the proximal end of the wireless electrode assembly may be shifted to a position against the heart wall after the distal end has been secured to the heart wall.

8. 发明公开

EP1957148A1 CARDIAC STIMULATION SYSTEM 有权
标题翻译：心脏起搏系统
公开(公告)号：EP1957148A1
公开(公告)日：2008-08-20
申请号：EP06825988.6
申请日：2006-10-13
申请人： Boston Scientific Scimed, Inc.
发明人： DRASLER, William J. , PIKUS, Michael J. , HASTINGS, Roger N. , SMITH, Scott R. , WILLARD, Martin R. , LAFONTAINE, Daniel M. , SAHOLT, Douglas R. , KVEEN, Graig L.
IPC分类号： A61N1/00 , A61B5/00
CPC分类号： A61N1/059 , A61B5/0031 , A61B5/042 , A61B5/6848 , A61B5/6882 , A61N1/0573 , A61N1/3684 , A61N1/37205 , A61N1/3756
摘要： Some embodiments of pacing systems employ wireless electrode assemblies to provide pacing therapy. The wireless electrode assemblies may wirelessly receive energy via an inductive coupling so as to provide electrical stimulation to the surrounding heart tissue. In certain embodiments, the wireless electrode assembly may be pivotable so that the proximal end of the wireless electrode assembly may be shifted to a position against the heart wall after the distal end has been secured to the heart wall.

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