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1. 发明申请

US20060078814A1 Toner processes and compositions thereof 失效
标题翻译：调色剂方法及其组合物
公开(公告)号：US20060078814A1
公开(公告)日：2006-04-13
申请号：US10963088
申请日：2004-10-12
申请人： Bing Hsieh , Richard Thompson
发明人： Bing Hsieh , Richard Thompson
IPC分类号： G03G9/08
CPC分类号： G03G9/09783 , G03G9/0804 , G03G9/0812 , G03G9/0819 , G03G9/08782 , G03G9/09 , G03G9/0926 , G03G9/09716 , G03G9/09725 , G03G9/09741 , G03G9/0975
摘要： The invention relates to color toner compositions prepared from a process for the preparation of a dry toner powder from an aqueous pigment concentrate dispersion comprising: blending at least an aqueous-based pigment concentrate dispersion and a resin to produce a paste; charging the paste to an extruder to generate an extruded pigment/resin mixture; dispersing the extruded pigment/resin mixture in a low boiling organic medium to create an organic phase; dispersing the organic phase in an aqueous phase containing a particulate stabilizer and mixing the organic phase and the aqueous phase at elevated temperature and under shear force to form toner particles of a controlled size and shape; removing the organic solvent and particulate stabilizer from the formed particles; and washing, drying, and collecting the particles for use as a dry toner powder.
摘要翻译：本发明涉及由水性颜料浓缩物分散体制备干燥调色剂粉末的方法制备的彩色调色剂组合物，包括：至少混合水基颜料浓缩物分散体和树脂以产生糊状物; 将糊料装入挤出机以产生挤出的颜料/树脂混合物; 将挤出的颜料/树脂混合物分散在低沸点有机介质中以产生有机相; 将有机相分散在含有颗粒稳定剂的水相中，并在高温和剪切力下混合有机相和水相以形成受控尺寸和形状的调色剂颗粒; 从形成的颗粒中除去有机溶剂和颗粒稳定剂; 并洗涤，干燥和收集颗粒以用作干燥调色剂粉末。

2. 发明申请

US20060078817A1 Toner processes and compositions thereof 审中-公开
标题翻译：调色剂方法及其组合物
公开(公告)号：US20060078817A1
公开(公告)日：2006-04-13
申请号：US10962942
申请日：2004-10-12
申请人： Bing Hsieh , Richard Thompson
发明人： Bing Hsieh , Richard Thompson
IPC分类号： G03G9/08
CPC分类号： G03G9/0821 , G03G9/0804 , G03G9/081 , G03G9/0812 , G03G9/0819 , G03G9/08782 , G03G9/0926
摘要： The invention relates to a process for the preparation of a dry toner powder from an aqueous pigment concentrate dispersion by blending at least an aqueous-based pigment concentrate dispersion and a resin compound to produce a paste; charging the paste to an extruder to generate a hot melt extrusion; dispersing the hot melt extrusion in a mixture of a surfactant and a high boiling organic medium in which the resin compound is substantially insoluble; mixing at elevated temperature and under shear force to form uniform particles of from about 2 microns to about 15 microns particle size; isolating and washing the particles in a low boiling hydrocarbon solvent; and drying and collecting the particles for use as a dry toner powder, and to the dry toner product produced by this process.
摘要翻译：本发明涉及一种通过将至少一种水基颜料浓缩物分散体和一种树脂化合物共混以产生糊状物从水性颜料浓缩物分散体制备干燥调色剂粉末的方法; 将糊料装入挤出机以产生热熔体挤出; 将热熔体挤出分散在表面活性剂和其中树脂化合物基本不溶的高沸点有机介质的混合物中; 在高温和剪切力下混合以形成约2微米至约15微米粒度的均匀颗粒; 在低沸点烃溶剂中分离和洗涤颗粒; 并干燥并收集用作干燥调色剂粉末的颗粒，以及通过该方法制备的干燥调色剂产品。

3. 发明申请

US20100303916A1 ENHANCED DRUG DELIVERY WITH ORIENTABLE PARTICLES 审中-公开
标题翻译：使用方便的颗粒加强药物输送
公开(公告)号：US20100303916A1
公开(公告)日：2010-12-02
申请号：US12678105
申请日：2008-09-23
申请人： Warren H. Finlay , Andrew R. Martin , Helen Orzanska , Richard Thompson
发明人： Warren H. Finlay , Andrew R. Martin , Helen Orzanska , Richard Thompson
IPC分类号： A61K9/14 , A61K31/353 , A61P11/00 , A61M37/00
CPC分类号： A61M15/02 , A61K9/0009 , A61K9/0078 , A61M2202/064 , A61M2205/0244 , A61M2205/3317
摘要： Small airway deposition of orientable drug particles in the lung due to interception is increased through alignment of these particles with an externally applied force such as a magnetic field. Drug particles in one embodiment are made magnetically responsive by loading them with magnetic nanoparticles. Elongated particles have a natural tendency to align parallel to the direction of flow through an airway, and therefore also parallel to airway walls; accordingly, alignment with a magnetic field to any other orientation increases interception, with a maximum increase for alignment perpendicular to airway walls. By positioning a magnetic field across a specific site within the lung, for example in the area of a tumor, the increase in deposition by interception allows localized targeting of inhaled drug particles to that area.
摘要翻译：通过这些颗粒与外部施加的力（例如磁场）的对准，增加了通过拦截导致肺中定向药物颗粒在肺中的小气道沉积。一个实施方案中的药物颗粒通过用磁性纳米颗粒加载而被制成磁性响应。细长的颗粒具有平行于通过气道的流动方向平行排列并因此也平行于气道壁的自然趋势; 因此，与任何其它方向的磁场对准增加截取，垂直于气道壁的对准最大增加。通过将磁场定位在肺内的特定部位（例如在肿瘤区域中），通过截取的沉积增加允许将吸入的药物颗粒定位到该区域。

4. 发明申请

US20070244382A1 Blood Analyte Determinations 审中-公开
标题翻译：血液分析物测定
公开(公告)号：US20070244382A1
公开(公告)日：2007-10-18
申请号：US11679839
申请日：2007-02-28
申请人： Mark Ries Robinson , Mike Borrello , Richard Thompson , Stephen Vanslyke , Steve Bernard , John O'Mahony
发明人： Mark Ries Robinson , Mike Borrello , Richard Thompson , Stephen Vanslyke , Steve Bernard , John O'Mahony
IPC分类号： A61B5/157
CPC分类号： A61B5/150961 , A61B5/14532 , A61B5/15003 , A61B5/150221 , A61B5/150229 , A61B5/150366 , A61B5/150992 , A61B5/153 , A61B5/155 , A61M1/1692 , A61M1/34 , A61M1/3621 , A61M1/3639 , A61M1/3663 , A61M5/16831 , A61M2005/1404 , A61M2205/3306 , A61M2205/331 , A61M2205/3331 , A61M2205/3334 , A61M2230/201
摘要： The present invention comprises methods and apparatuses that can provide measurement of glucose and other analytes with a variety of sensors without many of the performance-degrading problems of conventional approaches. An apparatus according to the present invention comprises a blood access system, adapted to remove blood from a body and infuse at least a portion of the removed blood back into the body. Such an apparatus also comprises an analyte sensor, mounted with the blood access system such that the analyte sensor measures the analyte in the blood that has been removed from the body by the blood access system. A method according to the present invention comprises removing blood from a body, using an analyte sensor to measure an analyte in the removed blood, and infusing at least a portion of the removed blood back into the body. The use of a non-contact sensor with a closed system creates a system will minimal infection risk.
摘要翻译：本发明包括可以提供葡萄糖和其他分析物与各种传感器的测量而不是常规方法的许多性能降级问题的方法和装置。根据本发明的装置包括血液存取系统，其适于从身体去除血液并且将至少一部分去除的血液注入体内。这种装置还包括安装有血液存取系统的分析物传感器，使得分析物传感器测量已经通过血液存取系统从体内除去的血液中的分析物。根据本发明的方法包括从身体去除血液，使用分析物传感器来测量去除的血液中的分析物，并将至少一部分去除的血液输入体内。使用具有封闭系统的非接触式传感器创建的系统将会最小的感染风险。

5. 发明申请

US20060165844A1 Preparation of yogurt containing confectionery pieces and product thereof 有权
标题翻译：含糖果糕及其制品的酸奶的制备
公开(公告)号：US20060165844A1
公开(公告)日：2006-07-27
申请号：US11388857
申请日：2006-03-24
申请人： Heidi O'Sullivan , Jennifer Maack , Leslie Miller , Joana Montenegro , Lisa Pannell , Richard Thompson
发明人： Heidi O'Sullivan , Jennifer Maack , Leslie Miller , Joana Montenegro , Lisa Pannell , Richard Thompson
IPC分类号： A23C9/12
CPC分类号： A23G1/46 , A23C9/1307 , A23C9/137 , A23C2210/30 , A23G1/54 , A23G3/2007 , A23G3/46 , A23G3/54
摘要： Methods of preparation for cultured milk based products and products prepared thereby are provided wherein a yogurt is produced containing 0.1% to about 5% confectionery filaments. The process involves providing a cooled fermented yogurt base at a temperature of 0° C. to 5° C.; injecting a liquid fat-bearing compound having a total fat concentration of 24% to about 40% into the cooled yogurt base; whereby the liquid fat-bearing compound is shattered into filaments upon contact with the cooled fermented yogurt.
摘要翻译：提供了制备培养的乳基产品和由此制备的产品的方法，其中制备含有0.1％至约5％糖果细丝的酸奶。该方法包括在0℃至5℃的温度下提供冷却的发酵酸奶基料。将总脂肪浓度为24％至约40％的含脂肪的化合物注射到冷却的酸奶基料中; 由此液体含脂化合物在与冷却的发酵酸奶接触时被粉碎成长丝。

6. 发明申请

US20060084780A1 Modified copolyesters and optical films including modified copolyesters 有权
标题翻译：改性共聚酯和包括改性共聚酯的光学膜
公开(公告)号：US20060084780A1
公开(公告)日：2006-04-20
申请号：US10967582
申请日：2004-10-18
申请人： Timothy Hebrink , Martin Denker , Bert Chien , Matthew Johnson , Richard Thompson , Kristopher Derks , William Merrill , Fuming Li
发明人： Timothy Hebrink , Martin Denker , Bert Chien , Matthew Johnson , Richard Thompson , Kristopher Derks , William Merrill , Fuming Li
IPC分类号： C08G63/02
CPC分类号： C08G63/189 , B32B27/36 , C08G63/181 , C08G63/183 , Y10T428/24942 , Y10T428/2495 , Y10T428/31507 , Y10T428/31786
摘要： Modified copolyesters having relatively low refractive indices and relatively high glass transition temperatures are disclosed. These modified copolyesters can be used in forming one or more layers in an optical film, such as a multilayer polymer film.
摘要翻译：公开了具有相对低的折射率和相对高的玻璃化转变温度的改性共聚酯。这些改性共聚酯可用于在诸如多层聚合物膜的光学膜中形成一层或多层。

7. 发明申请

US20060068075A1 Flavored yogurt products and methods of making same 审中-公开
标题翻译：调味酸奶产品及其制作方法
公开(公告)号：US20060068075A1
公开(公告)日：2006-03-30
申请号：US10955443
申请日：2004-09-30
申请人： Jerry Fultz , Maeve Murphy , Lisa Pannell , Gary Stoddard , Dena Strehlow , Alejandro Barajas , Richard Thompson
发明人： Jerry Fultz , Maeve Murphy , Lisa Pannell , Gary Stoddard , Dena Strehlow , Alejandro Barajas , Richard Thompson
IPC分类号： A23C21/00
CPC分类号： A23C9/13 , A23C9/1307 , A23C2210/30
摘要： The invention provides fermented dairy products composed of fermented dairy base containing active cultures and a low water activity sweet brown base component admixed within the fermented dairy base. Further, the invention provides methods for preparing fermented dairy products including steps of fermenting a dairy base by lactic fermentation to a pH of 4.7 to 5.3 to provide a fermented dairy base; cooling the fermented dairy base; admixing a sweet brown base component with the fermented dairy base to form a sweet brown flavored fermented dairy product; and packaging the sweet brown flavored fermented dairy product. Methods of formulating yogurt compositions are also described.
摘要翻译：本发明提供由含有活性培养物的发酵乳基质和混合在发酵乳制品基质内的低水活性甜棕基组分组成的发酵乳制品。此外，本发明提供了制备发酵乳制品的方法，包括通过乳酸发酵将乳制品基质发酵至pH为4.7至5.3的步骤，以提供发酵乳制品基料; 冷却发酵乳品基地; 将甜棕色基础组分与发酵乳制品基质混合以形成甜棕色风味发酵乳制品; 并包装甜棕色风味的发酵乳制品。还描述了配制酸奶组合物的方法。

8. 发明申请

US20050142067A1 Zintrodes, multitrodes and uses thereof 审中-公开
标题翻译： Zintrodes，多色及其用途
公开(公告)号：US20050142067A1
公开(公告)日：2005-06-30
申请号：US10929924
申请日：2004-08-30
申请人： Christopher Frederickson , Carol Fierke , Richard Thompson
发明人： Christopher Frederickson , Carol Fierke , Richard Thompson
IPC分类号： A01N55/02 , A61B20060101 , A61B5/00 , C12Q1/00 , C12Q1/34 , G01N21/77 , G01N27/26 , G01N31/22 , G01N33/50 , G01N33/68 , G01N33/84
CPC分类号： G01N31/22 , G01N21/7703 , G01N33/6896 , G01N33/84 , G01N2021/773 , G01N2021/7786 , G01N2800/28
摘要： Provided herein are zintrodes to measure intracranial free zinc levels in an individual or free zinc levels in solution. The zintrodes and multitrodes comprise a zinc chelator and a fluorophore or may comprise only a zinc-chelating fluorophore, an optical fiber having an optical tip, and a means of entrapping the zinc chelator and the fluorophore or the zinc-chelating fluorophore proximate to the optical tip within the zintrode. The zintrode may comprise a multitrode. Also provided are methods of real-time buffering of zinc ion levels in vivo in brain tissue to treat an excitotoxic neural injury using the zintrodes and multitrodes described herein. Additionally, provided herein are a system and method to measure pZn in solution.
摘要翻译：本文提供了测定溶液中个体或游离锌水平的颅内游离锌水平的锌土。锌铁和多晶硅包括锌螯合剂和荧光团，或者可以仅包含锌螯合荧光团，具有光学尖端的光纤，以及将锌螯合剂和荧光团或螯合螯合的螯合荧光团截留在光学附近的手段提示在zintrode。锌土矿可以包括多铁。还提供了在脑组织中实时缓冲锌离子水平的方法来治疗兴奋性中毒性神经损伤，其使用本文所述的锌铁和多色。此外，本文提供的是测量溶液中pZn的系统和方法。

9. 发明申请

US20050024284A1 Microwave demulsification of hydrocarbon emulsion 有权
标题翻译：微波乳化乳化液
公开(公告)号：US20050024284A1
公开(公告)日：2005-02-03
申请号：US10619011
申请日：2003-07-14
申请人： James Halek , Philip Harris , Richard Thompson , Robert Ferri , Jonathan Squires
发明人： James Halek , Philip Harris , Richard Thompson , Robert Ferri , Jonathan Squires
IPC分类号： H01Q1/04 , H01Q13/12 , H01Q13/10
CPC分类号： H01Q1/04 , H01Q13/12
摘要： Recovery of hydrocarbons, such as petroleum products, from a liquid or solid substrate is facilitated by the use of microwave energy to energize and separate molecular bonds between the hydrocarbons and the substrate. A radio frequency (RF) applicator delivers microwave energy to a treatment volume containing an emulsion of a hydrocarbon and a substrate. Delivering the microwave energy to the emulsion facilitates separation of the hydrocarbon and substrate molecules into layers. Hydrocarbons and other products can then be recovered from their respective layers. The treatment volume may be located either above or below ground. The RF applicator may include an antenna body with slots formed substantially parallel to one another in a substantially horizontal orientation. The RF applicator efficiently delivers microwave energy into the treatment volume. Substantially all of the power supplied to the RF applicator is radiated, with very little power reflected internally within the RF applicator.
摘要翻译：通过使用微波能量来激发和分离烃和基底之间的分子键，促进从液体或固体基质中回收烃类如石油产品。射频（RF）施加器将微波能量传递到含有烃和基底的乳液的处理体积。将微波能量提供给乳液有助于将烃和底物分子分离成层。然后可以从各自的层回收碳氢化合物和其他产物。治疗体积可以位于地面上方或下方。 RF施加器可以包括天线体，其具有基本上水平的方向基本上彼此平行的槽形成。 RF施加器有效地将微波能量传递到处理体积中。基本上所有供给到RF施加器的功率被辐射，其中在RF施加器内部反射的功率非常小。

10. 发明申请

US20050020652A1 Peroxisome proliferator activated receptor agonists 失效
标题翻译：过氧化物酶体增殖物激活受体激动剂
公开(公告)号：US20050020652A1
公开(公告)日：2005-01-27
申请号：US10496770
申请日：2002-11-26
申请人： Tracey Gibson , Richard Johnston , Nathan Mantlo , Richard Thompson , Leonard Winneroski , Yanping Xu , Xiaodong Wang
发明人： Tracey Gibson , Richard Johnston , Nathan Mantlo , Richard Thompson , Leonard Winneroski , Yanping Xu , Xiaodong Wang
IPC分类号： A61K31/4174 , A61K31/443 , A61K31/4709 , A61P3/04 , A61P3/06 , A61P3/10 , A61P9/00 , A61P9/12 , A61P43/00 , C07D233/32 , C07D233/66 , C07D233/70 , C07D233/76 , C07D233/78 , C07D401/06 , C07D403/12 , C07D405/06 , C07D405/12 , A61K31/4178 , A61K31/4166
CPC分类号： C07D401/06 , C07D233/32 , C07D233/70 , C07D233/76 , C07D403/12 , C07D405/06 , C07D405/12
摘要： The present invention is directed to compounds represented by the following structural Formula (I), (a) R1 is selected from the group consisting of hydrogen, substituted or unsubstituted group selected from C1-C8 alkyl, aryl-C0-4-alkyl, heteroaryl-C0-4-alkyl, C6 cycloalkylaryl-C0-2-alkyl, and —CH2—C(O)—R17-R18, wherein R17 is O or NH and R18 is optionally substituted benzyl; (b) R2 is selected from the group consisting of C1-C6 alkyl, C1-C6 alkenyl, aryl-C0-4-alkyl, heteroaryl-C0-4-alkyl, C1-C4 alkyl sulfonamide, C1-C4 alkyl amide, OR10 and C3-C6 cycloalkyl; (c) W is O or S; (d) X is an optionally substituted C1-C5 alkylene linker wherein one carbon atom of the linker may optionally be replaced with O, NH, S, and optionally two carbons together may form a double bond; (e) Y is selected from the group consisting of C, O, S, NH and a single bond; and (f) E is selected from the group consisting of C(R3) (R4)A, A, and a substituted or unsubstituted group selected from the group consisting of (CH2)n COOR19.
摘要翻译：本发明涉及由以下结构式（I）表示的化合物，（a）R 1选自氢，取代或未取代的选自C 1 -C 8烷基，芳基-C 0-4 - 烷基，杂芳基 -C 0-4 - 烷基，C6环烷基芳基-C0-2 - 烷基和-CH2-C（O）-R17-R18，其中R17是O或NH，R18是任选取代的苄基; （b）R 2选自C 1 -C 6烷基，C 1 -C 6烯基，芳基-C 0-4 - 烷基，杂芳基-C 0-4 - 烷基，C 1 -C 4烷基磺酰胺，C 1 -C 4烷基酰胺，OR 10 和C 3 -C 6环烷基; （c）W为O或S; （d）X是任选取代的C1-C5亚烷基连接体，其中连接体的一个碳原子可以任选地被O，NH，S取代，并且任选地两个碳可以一起形成双键; （e）Y选自C，O，S，NH和单键; 和（f）E选自C（R 3）（R 4）A，A和选自（CH 2）n COOR 19的取代或未取代的基团。

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