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    • 7. 发明授权
    • Method and system for using inverted data to detect corrupt data
    • 使用反向数据检测损坏数据的方法和系统
    • US5699509A
    • 1997-12-16
    • US484704
    • 1995-06-07
    • Scott P. GaryDavid E. PopeTao Chang
    • Scott P. GaryDavid E. PopeTao Chang
    • G06F11/08G06F11/16G06F12/16G11C29/00G06F11/00
    • G06F11/167G06F11/08G11C29/74G06F2201/865
    • Errors in data stored in the memory of a computer are detected prior to use of the data. A protected data type is declared in writing a program in which errors in critical data must be detected before the data are used. The invention is preferably implemented on a personal computer system (10) or in a microcontroller for a device. When a protected data item is initialized, both the protected data item and its corresponding bit-inverted form are stored in memory. A constructor function is used to determine the bit-inverted form. Any time that the protected data item is subsequently accessed for use by an application program, either the stored protected data item or its corresponding bit-inverted form are inverted for comparison to the other stored data item. Any difference detected in this comparison indicates that a change has occurred in either or both of the protected data item and its corresponding bit-inverted form within memory. Depending upon the application program in which the invention is used, an appropriate action is taken upon detecting such an error, such as providing an indication of the error and terminating further execution of the program.
    • 在使用数据之前检测存储在计算机存储器中的数据的错误。 受保护的数据类型在编写程序时被声明,在使用数据之前必须检测关键数据中的错误。 本发明优选地在个人计算机系统(10)或设备的微控制器中实现。 当受保护的数据项被初始化时,受保护的数据项及其对应的位反转形式被存储在存储器中。 构造函数用于确定位反转形式。 随后受保护的数据项随后被访问以供应用程序使用,所存储的受保护数据项或其对应的位反转形式被反转,以与其他存储的数据项进行比较。 在该比较中检测到的任何差异表示在存储器内的受保护数据项和其对应的位倒置形式中的任何一个或两者中发生了改变。 根据使用本发明的应用程序,在检测到这种错误时采取适当的动作,例如提供错误的指示并终止程序的进一步执行。
    • 10. 发明授权
    • Control of a multi-channel drug infusion pump using a pharmacokinetic
model
    • 使用药代动力学模型控制多通道药物输注泵
    • US5522798A
    • 1996-06-04
    • US324392
    • 1994-10-17
    • Noel L. JohnsonJyh-yi T. HuangTao Chang
    • Noel L. JohnsonJyh-yi T. HuangTao Chang
    • A61M5/168A61M5/172A61M31/00
    • A61M5/172A61M5/16827
    • A host controller (10) selectively predicts and controls drug concentrations for each of a plurality of channels delivered through multiple drug channels of a multi-channel drug delivery system. The host controller includes a controller (32) that is coupled to each drug channel of the multi-channel drug delivery system to receive actual drug delivery rate information. Delivery of each drug can be selectively separately controlled by a PK model (the same PK model for each channel or different PK models for different channels) to achieve either a desired setpoint for a blood plasma drug concentration or a setpoint for an effect compartment drug concentration. Control of the drug delivery by the PK model can be selectively interrupted during operation of the multi-channel drug delivery system, to switch to a manual mode in order to administer a bolus dose or a continuous infusion, and then, control of drug infusion using the PK model can be subsequently resumed. The blood plasma and/or effect compartment drug concentrations for any drug predicted in accordance with a PK model are selectively displayed to a user on an electroluminescent (EL) display (36), even during operation of the multi-channel drug delivery system in the manual mode, or after the drug delivery has been terminated. Prediction of drug concentration is tracked for each drug administered, enabling multiple drugs to successively administered in the same drug channel and control of a drug delivery by the PK model to continue when the drug channel used to administer the drug is changed.
    • 主控制器(10)选择性地预测并控制通过多通道药物递送系统的多个药物通道递送的多个通道中的每个通道的药物浓度。 主机控制器包括与多通道药物递送系统的每个药物通道耦合以接收实际药物递送速率信息的控制器(32)。 每种药物的递送可以通过PK模型(每个通道的相同PK模型或不同通道的不同PK模型)选择性地分别控制,以实现血浆药物浓度的期望设定值或用于效应室药物浓度的设定点 。 在多通道药物递送系统的操作期间可以选择性地中断通过PK模型的药物递送的控制,以切换到手动模式,以便施用推注剂量或连续输注,然后使用 可以随后恢复PK模型。 在电致发光(EL)显示器(36)上选择性地向使用者显示根据PK模型预测的任何药物的血浆和/或效应室药物浓度,即使在多通道药物递送系统 手动模式,或药物递送终止后。 跟踪每种药物的药物浓度的预测,使得多个药物在相同的药物通道中连续施用,并且当用于施用药物的药物通道改变时,通过PK模型控制药物递送继续。