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1. 发明申请

US20170216295A1 CCR9 ANTAGONIST COMPOUNDS 审中-公开
公开(公告)号：US20170216295A1
公开(公告)日：2017-08-03
申请号：US15501103
申请日：2015-07-27
申请人： Bhuamik Pandya , Blaise Lippa , Xin Zhang , Jon Christian Baber , Jan Antionette C. Romero , Jing Zhang
发明人： Bhuamik Pandya , Blaise Lippa , Xin Zhang , Jon Christian Baber , Jan Antionette C. Romero , Jing Zhang
IPC分类号： A61K31/519 , C07D487/04
CPC分类号： A61K31/519 , C07D487/04
摘要： Provided herein are compounds that inhibit CCR9 receptor function. Also provided herein are methods of treating inflammatory disease in a subject, comprising administering to the subject a compound of the invention. Accordingly, in one aspect, provided herein is a compound of Formula (1) or a pharmaceutically acceptable salt thereof. In another aspect, provided herein is a pharmaceutical composition, comprising a compound of Formula (1), and a pharmaceutically acceptable carrier.

2. 外观设计

USD859111S1 Pliers jaw 有权
公开(公告)号：USD859111S1
公开(公告)日：2019-09-10
申请号：US29622905
申请日：2017-10-20
申请人： Xin Zhang
设计人： Xin Zhang

3. 外观设计

USD835491S1 Pliers grip handles 有权
公开(公告)号：USD835491S1
公开(公告)日：2018-12-11
申请号：US29613469
申请日：2017-08-10
申请人： Xin Zhang
设计人： Xin Zhang

4. 发明授权

US09951092B2 Methods, compositions, devices, and kits for performing phospholipid separation 有权
公开(公告)号：US09951092B2
公开(公告)日：2018-04-24
申请号：US13580884
申请日：2011-05-20
申请人： Pamela C. Iraneta , Thomas H. Walter , Xin Zhang , Daniel P. Walsh , Kevin D. Wyndham , Raymond P. Fisk
发明人： Pamela C. Iraneta , Thomas H. Walter , Xin Zhang , Daniel P. Walsh , Kevin D. Wyndham , Raymond P. Fisk
IPC分类号： C07F9/10 , B01D15/32 , B01J20/28 , B01J20/287 , B01J20/32 , B01J20/10 , B01D15/22 , B01L3/00 , C07K1/30 , G01N30/88
CPC分类号： C07F9/103 , B01D15/22 , B01D15/327 , B01J20/103 , B01J20/28004 , B01J20/28019 , B01J20/28061 , B01J20/28069 , B01J20/287 , B01J20/3204 , B01J20/3217 , B01J20/3246 , B01J20/3293 , B01J2220/64 , B01L3/5023 , B01L3/50255 , B01L2300/0681 , C07K1/30 , G01N2030/8813
摘要： Methods, kits and devices for separating phospholipids and proteins from small molecules in biochemical samples can feature an apparatus having a wetting barrier, at least one fit and a separation media. For example, an apparatus can include at least one wall defining a chamber having an exit and an entrance; a wetting barrier disposed between the exit and entrance, so as to define a separation media space located between the wetting barrier and the exit and a sample receiving area located between the wetting barrier and the entrance; and a separation media disposed adjacent to the wetting barrier and having a specific affinity for phospholipids. The wetting barrier is adapted to (i) retain the liquid sample and a protein precipitating agent in the sample receiving area under a first force, thereby facilitating the formation of a protein precipitate and a processed sample, and (ii) flow the processed sample through the wetting barrier and separation media under a second force, wherein the second force is greater than the first force, thereby retaining the protein precipitate in the sample receiving area, retaining phospholipids in the separation media, and eluting small molecules.

5. 发明授权

US08992043B2 Constructive occlusion lighting system and applications thereof 有权
标题翻译：建筑遮挡照明系统及其应用
公开(公告)号：US08992043B2
公开(公告)日：2015-03-31
申请号：US13579164
申请日：2011-02-15
申请人： Craig Eugene Marquardt , Heather Waugh , Xin Zhang
发明人： Craig Eugene Marquardt , Heather Waugh , Xin Zhang
IPC分类号： F21V13/02 , F21V7/00 , F21Y101/02 , F21Y103/02
CPC分类号： F21V7/0058 , F21Y2103/33 , F21Y2115/10
摘要： A luminaire includes at least one light source, at least one reflector having a reflector cavity and an optical element positioned to receive light reflected from the at least one reflector cavity. The luminaire does not include a mask or other structure located within the opening of the luminaire that would partially occlude light exiting the luminaire—light can thus exit the luminaire unimpeded. In some embodiments, the at least one reflector cavity is semi toroidal. Moreover, in some embodiments, the optical element includes a reflective optical element, a refractive optical element or a combination thereof. Methods of lighting a surface are also described.
摘要翻译：照明器包括至少一个光源，至少一个具有反射器腔的反射器和定位成接收从所述至少一个反射器腔反射的光的光学元件。照明器不包括位于照明器的开口内的掩模或其他结构，其将部分遮挡出离开照明器光的光，从而可以不受阻碍地离开照明器。在一些实施例中，至少一个反射器腔是半环形的。此外，在一些实施例中，光学元件包括反射光学元件，折射光学元件或其组合。还描述了照亮表面的方法。

6. 发明申请

US20150079072A1 Assays to Monitor Bleeding Disorders 审中-公开
标题翻译：监测出血障碍的分析
公开(公告)号：US20150079072A1
公开(公告)日：2015-03-19
申请号：US14234789
申请日：2012-07-25
申请人： Jurg Sommer , Haiyan Jiang , Xin Zhang , Buyue Yang , Glenn Pierce
发明人： Jurg Sommer , Haiyan Jiang , Xin Zhang , Buyue Yang , Glenn Pierce
IPC分类号： G01N33/86 , C12N9/64
CPC分类号： G01N33/86 , C12N9/644 , G01N2333/755 , G01N2333/9645 , G01N2333/974
摘要： The present invention provides methods of dosing Factor VIII or Factor IX chimeric and hybrid polypeptides. The present invention further provides high-sensitivity methods of quantifying an amount of activated FIX protein in a test sample
摘要翻译：本发明提供了给予因子VIII或因子IX嵌合和杂交多肽的方法。本发明还提供了定量测试样品中活化的FIX蛋白的量的高灵敏度方法

7. 发明授权

US08865332B2 Nickel-hydrogen battery pack heat removal system for hybrid vehicle 有权
标题翻译：混合动力汽车用镍氢电池组除热系统
公开(公告)号：US08865332B2
公开(公告)日：2014-10-21
申请号：US12999582
申请日：2009-01-16
申请人： Yalian Yang , Xin Zhang , Datong Qin , Yong Ren , Anjian Zhou , Minghui Hu , Ling Su , Chuanlin Zhao
发明人： Yalian Yang , Xin Zhang , Datong Qin , Yong Ren , Anjian Zhou , Minghui Hu , Ling Su , Chuanlin Zhao
IPC分类号： H01M10/50 , B60L3/00 , H01M10/6563 , B60L11/18 , H01M10/613 , H01M10/30 , H01M10/625 , H01M10/617 , H01M10/635 , H01M2/10 , H01M10/6566
CPC分类号： H01M10/5004 , B60L3/0046 , B60L11/1874 , H01M2/105 , H01M10/30 , H01M10/613 , H01M10/617 , H01M10/625 , H01M10/635 , H01M10/6563 , H01M10/6566 , Y02E60/124 , Y02T10/7005 , Y02T10/7055
摘要： A nickel-hydrogen battery pack heat removal system for hybrid vehicle is provided. The system includes a battery box, a power battery pack (8), a battery support frame (9), a support bar (5), an air inlet (1), an air outlet (6) and a fan (7). Batteries in the power battery pack (8) are aligned in parallel in two layers one above the other in the battery support frame (9) of the battery box, and the support bar (5) and the battery support frame (9) are fixed on the upper and lower soleplates respectively of the battery box. The air inlet (1) is set at one end of the battery box, the air outlet (6) is set at the other end of the battery box, and the fan (7) is fitted at the air outlet (6). The system further includes conduction plates (2) in the shape of circular arcs, said conduction plates (2) being fitted on the opposing faces of the two upper and lower batteries which are closest to the air inlet (1).
摘要翻译：提供了一种用于混合动力车辆的镍氢电池组散热系统。该系统包括电池盒，动力电池组（8），电池支撑框架（9），支撑杆（5），进气口（1），出气口（6）和风扇（7）。动力电池组（8）中的电池在电池盒的电池支撑框架（9）中彼此并排地并排排列，并且支撑杆（5）和电池支撑框架（9）固定在电池盒的上，下底板上。空气入口（1）设置在电池盒的一端，空气出口（6）设置在电池盒的另一端，风扇（7）安装在出风口（6）处。该系统还包括圆弧形的导电板（2），所述导电板（2）装配在最靠近空气入口（1）的两个上部和下部电池的相对面上。

8. 发明申请

US20140259599A1 TORQUE GUN WITH VISION SYSTEM 审中-公开
标题翻译：扭力枪与视觉系统
公开(公告)号：US20140259599A1
公开(公告)日：2014-09-18
申请号：US13949809
申请日：2013-07-24
申请人： Jared L. Glaspell , Brent Allen Bowers , Mengtang Sun , Zewen Yu , Xin Zhang , Richard J. Barr , Kevin P. Swanger
发明人： Jared L. Glaspell , Brent Allen Bowers , Mengtang Sun , Zewen Yu , Xin Zhang , Richard J. Barr , Kevin P. Swanger
IPC分类号： B23Q17/24 , B25B21/00
CPC分类号： B25B21/00 , B25B23/00 , Y10T29/49769
摘要： A hand-held torque tool includes a hand tool chassis and a vision system. The hand tool chassis includes a motor configured to operate a work head and a camera located in a fixed position relative to the work head. The vision system includes a wireless controller which transmits images captured by the camera, a wireless display located remotely from the hand tool chassis that is configured to display images captured by the camera, and a mounting structure attached to the wireless display. The mounting structure is configured to be placed on or about a portion of a body of a user of the hand-held torque tool. Methods of tightening a fastener and installing automobile components within an automobile are also provided.
摘要翻译：手持扭矩工具包括手工工具底盘和视觉系统。手动工具底盘包括电动机，其构造成操作相对于工作头位于固定位置的工作头和照相机。视觉系统包括：无线控制器，其发送由相机拍摄的图像，远离手工工具机架的无线显示器，其被配置为显示由相机拍摄的图像;以及安装结构，附接到无线显示器。安装结构被配置为放置在手持扭矩工具的使用者的身体的一部分上或周围。还提供了紧固紧固件和在汽车内安装汽车部件的方法。

9. 发明授权

US08711313B2 Structure of pixel electrode 有权
标题翻译：像素电极的结构
公开(公告)号：US08711313B2
公开(公告)日：2014-04-29
申请号：US13381891
申请日：2011-08-30
申请人： Xin Zhang
发明人： Xin Zhang
IPC分类号： G02F1/1343 , G02F1/1337
CPC分类号： G02F1/133707 , G02F1/133753 , G02F1/134336 , G02F2001/133757 , G02F2201/40
摘要： A structure of pixel electrode includes a strip-like horizontal main trunk and a strip-like vertical main trunk, the horizontal main trunk and the vertical main trunk centrally and perpendicularly intersecting each other; a plurality of strip-like branches arranged in each of four domains that are formed by being equally divided by the central perpendicular intersection of the horizontal main trunk and the vertical main trunk, the plurality of strip-like branches extending outward from a central point of the perpendicular intersection of the vertical main trunk and the horizontal main trunk, the plurality of strip-like branches being spaced by a plurality of slits; and two centrally symmetric polygonal or sector openings provided in a central zone at the central perpendicular intersection of the horizontal main trunk and the vertical main trunk.
摘要翻译：像素电极的结构包括条状水平主干和条状垂直主干，水平主干和垂直主干中心并垂直相交; 多个条状分支被布置在由水平主干和垂直主干的中心垂直交点相等地划分的四个域中的每一个中，多个条状分支从中心点向外延伸垂直主干和水平主干的垂直交点，多个条状分支间隔开多个狭缝; 以及设置在水平主干和垂直主干的中心垂直交叉处的中心区域中的两个中心对称的多边形或扇形开口。

10. 发明授权

US08610854B2 Liquid crystal display panel and pixel electrode thereof 有权
标题翻译：液晶显示面板及其像素电极
公开(公告)号：US08610854B2
公开(公告)日：2013-12-17
申请号：US13381365
申请日：2011-08-30
申请人： Xin Zhang
发明人： Xin Zhang
IPC分类号： G02F1/1337
CPC分类号： G02F1/1333 , G02F1/133707 , G02F1/134309
摘要： A pixel electrode of a liquid crystal display panel is electrically connected to an end of a switch unit of the liquid crystal display panel, and includes: a plurality of branches, which is connected to a frame, each of the branches extending from the frame at a given angle into an interior of the frame; adjacent ones of the branches being sequentially juxtaposed by being spaced by cutoffs; the plurality of branches having tailing ends that define an opening having a configuration of mirror symmetry in the interior of the frame; and an orientation layer being arranged below the frame to cover the frame. Through use of the pixel electrode of the present invention, the liquid crystal display panel shows increased transmittance and improved displaying performance.
摘要翻译：液晶显示面板的像素电极电连接到液晶显示面板的开关单元的端部，并且包括：多个分支，其连接到框架，每个分支从框架延伸到给定的角度进入框架的内部; 相邻的分支通过被间隔开地并列; 所述多个分支具有限定在框架内部具有镜像对称的构造的开口的尾端; 并且定位层布置在框架下方以覆盖框架。通过使用本发明的像素电极，液晶显示面板的透射率提高，显示性能提高。

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