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1. 发明授权

US06414184B1 Process for producing polyisocyanates containing biuret groups from (cyclo)aliphatic diisocyanates 有权
标题翻译：从（环）脂族二异氰酸酯制备含有缩二脲基团的多异氰酸酯的方法
公开(公告)号：US06414184B1
公开(公告)日：2002-07-02
申请号：US09242288
申请日：1999-02-10
申请人： Bernd Bruchmann , Martin Reif , Werner Hofscheuer , Joachim Jähme , Werner Langer , Hans Renz , Günter Mohrhardt , Michael Schiessl
发明人： Bernd Bruchmann , Martin Reif , Werner Hofscheuer , Joachim Jähme , Werner Langer , Hans Renz , Günter Mohrhardt , Michael Schiessl
IPC分类号： C08G1810
CPC分类号： C08G18/7831 , C07C273/1827 , C08G2101/0008 , C08G2101/0025 , C07C275/62
摘要： A process for preparing biuret-functional polyisocyanates from at least one aliphatic or cycloaliphatic diisocyanate and from at least one amine or water or a mixture thereof as reactants involves mixing the reactants with one another in a mixing unit having a high shear action.
摘要翻译：从至少一种脂族或脂环族二异氰酸酯和至少一种胺或水或其混合物制备缩二脲官能的多异氰酸酯作为反应物的方法包括在具有高剪切作用的混合单元中将反应物彼此混合。

2. 发明授权

US09710232B2 Computer-aided method for producing a software-based analysis module 有权
公开(公告)号：US09710232B2
公开(公告)日：2017-07-18
申请号：US13642567
申请日：2011-04-20
申请人： Michael Schiessl , Sabrina Duda , Andreas Thoelke
发明人： Michael Schiessl , Sabrina Duda , Andreas Thoelke
IPC分类号： G06F9/44 , G06Q30/02
CPC分类号： G06F8/20 , G06Q30/02
摘要： The invention relates to a computer-assisted method for generating a software-based analysis module for analysis of electronic raw data representing a detected stimulus response of a test subject in a test project. The method comprises the following steps: supplying logic data representing a user-defined calculation logic in an application software implemented on a computer unit, supplying project data representing a user-defined project definition with a structured order of project entities of the test project in the application software, generating product setup parameter data by assigning the user-defined calculation logic to the project entities in the assignment of the logic data to the project data, and the project setup parameters for the project entities of the test project are derived therefrom, the project setup parameter data for a data output are supplied via a user interface and the assigned user entries are detected for a portion of the project setup parameter data, and an analysis module is generated in accordance with the logic data, the project data and the project setup parameter data, which are configured to receive electronic raw data representing a detected stimulus response of a test subject and to process said electronic raw data for analyzing the response of the test subject.

3. 发明授权

US5942589A Preparation of semicrystalline syndiotactic polymers of vinylaromatic monomers 失效
标题翻译：制备乙烯基芳族单体的半结晶间同立构聚合物
公开(公告)号：US5942589A
公开(公告)日：1999-08-24
申请号：US905236
申请日：1997-08-01
申请人： Josef Wunsch , Michael Schiessl , Ralph Diener
发明人： Josef Wunsch , Michael Schiessl , Ralph Diener
IPC分类号： C08F4/642 , B01J19/20 , B01J19/24 , C08F4/659 , C08F4/6592 , C08F12/04 , C08F112/00 , C08F112/08 , C08F12/02
CPC分类号： B01J19/24 , B01J19/20 , C08F12/04 , B01J2219/00094 , C08F2420/04
摘要： Essentially syndiotactic and semicrystalline polymers which comprise vinylaromatic monomers arc prepared from a reaction mixture containing, as components, vinylaromatic compounds, metallocene complexes as catalysts and one or more cocatalysts selected from the group consisting of the strong, neutral Lewis acids, the ionic compounds having Lewis acid cations and the ionic compounds having Bronsted acids as cations, by a process in which the components are premixed before entering the reactor.
摘要翻译：包含乙烯基芳族单体的基本间同立构和半结晶聚合物由含有作为组分的乙烯基芳族化合物，作为催化剂的茂金属络合物和一种或多种选自强中性路易斯酸的助催化剂的反应混合物制备，所述离子化合物具有路易斯通过其中组分在进入反应器之前被预混合的方法，酸阳离子和具有Br + E，uml + EE n酸的阳离子的离子化合物。

4. 发明申请

US20130263079A1 COMPUTER-AIDED METHOD FOR PRODUCING A SOFTWARE-BASED ANALYSIS MODULE 审中-公开
标题翻译：用于生成基于软件的分析模块的计算机辅助方法
公开(公告)号：US20130263079A1
公开(公告)日：2013-10-03
申请号：US13642567
申请日：2011-04-20
申请人： Michael Schiessl , Sabrina Duda , Andreas Thoelke
发明人： Michael Schiessl , Sabrina Duda , Andreas Thoelke
IPC分类号： G06F9/44
CPC分类号： G06F8/20 , G06Q30/02
摘要： The invention relates to a computer-assisted method for generating a software-based analysis module for analysis of electronic raw data representing a detected stimulus response of a test subject in a test project. The method comprises the following steps: supplying logic data representing a user-defined calculation logic in an application software implemented on a computer unit, supplying project data representing a user-defined project definition with a structured order of project entities of the test project in the application software, generating product setup parameter data by assigning the user-defined calculation logic to the project entities in the assignment of the logic data to the project data, and the project setup parameters for the project entities of the test project are derived therefrom, the project setup parameter data for a data output are supplied via a user interface and the assigned user entries are detected for a portion of the project setup parameter data, and an analysis module is generated in accordance with the logic data, the project data and the project setup parameter data, which are configured to receive electronic raw data representing a detected stimulus response of a test subject and to process said electronic raw data for analyzing the response of the test subject.
摘要翻译：本发明涉及一种用于生成用于分析表示测试项目中测试对象的检测到的刺激响应的电子原始数据的基于软件的分析模块的计算机辅助方法。该方法包括以下步骤：在计算机单元上实现的应用软件中提供表示用户定义的计算逻辑的逻辑数据，将表示用户定义的项目定义的项目数据提供给测试项目的项目实体的结构化顺序应用软件，通过将项目实体的逻辑数据分配给项目数据，将用户定义的计算逻辑分配给项目数据，生成产品设置参数数据，并从中推导出项目实体的项目设置参数，通过用户界面提供数据输出的项目设置参数数据，并为项目设置参数数据的一部分检测分配的用户条目，并根据逻辑数据，项目数据和项目生成分析模块设置参数数据，其被配置为接收表示检测到的刺激响应的电子原始数据并处理所述电子原始数据以分析测试对象的响应。

5. 发明授权

US6144889A Method of generating and storing and operating an user program consisting of instructions for a stored-program control unit 失效
标题翻译：一种生成和存储和操作由存储程序控制单元的指令组成的用户程序的方法
公开(公告)号：US6144889A
公开(公告)日：2000-11-07
申请号：US029330
申请日：1998-05-18
申请人： Heiko Kammler , Michael Schiessl
发明人： Heiko Kammler , Michael Schiessl
IPC分类号： G05B19/05 , G05B19/42
CPC分类号： G05B19/056
摘要： During the program execution of a user program, the function code assigned to an output signal and the function parameters assigned to this function code are read first. For each function parameter, depending on whether this refers to an input signal or to another instruction, either the input signal is stored temporarily or a branch is made to the other instruction and its function code and function parameters are executed. The generation of the user program is carried out in a similar way. In addition, however, the storage or the as-valid identification of the user program is prevented if the function parameters of all the instructions of at least one output signal have not all been input.
摘要翻译： PCT No.PCT / EP96 / 03744 Sec。 371日期1998年5月18日 102（e）日期1998年5月18日PCT提交1996年8月23日PCT公布。出版物WO97 / 09661 日期1997年03月13日在程序执行用户程序期间，首先读取分配给输出信号的功能代码和分配给该功能代码的功能参数。对于每个功能参数，根据这是指一个输入信号还是另一个指令，输入信号被暂时存储，或者对其他指令进行分支，并且执行其功能代码和功能参数。以类似的方式执行用户程序的生成。然而，此外，如果至少一个输出信号的所有指令的功能参数尚未全部输入，则防止用户程序的存储或有效的标识。

6. 发明授权

US6120802A Method of producing multi-layer medicaments in solid form for oral or rectal administration 失效
标题翻译：生产用于口服或直肠给药的固体形式的多层药物的方法
公开(公告)号：US6120802A
公开(公告)日：2000-09-19
申请号：US51544
申请日：1998-04-15
申请人： Jorg Breitenbach , Axel Paul Hartl , Jurgen Hofmann , Joerg Rosenberg , Michael Schiessl , Hans Dieter Zettler
发明人： Jorg Breitenbach , Axel Paul Hartl , Jurgen Hofmann , Joerg Rosenberg , Michael Schiessl , Hans Dieter Zettler
IPC分类号： A61J3/10 , A61K9/20 , A61K9/24 , A61K9/28 , A61K31/07 , A61K31/167 , A61K31/192 , A61K31/277 , A61K31/355 , A61K31/375 , A61K31/401 , A61K31/4422 , A61K31/52 , A61K31/522 , A61K31/60 , A61K9/36
CPC分类号： A61J3/10 , A61K31/07 , A61K31/167 , A61K31/192 , A61K31/277 , A61K31/355 , A61K31/375 , A61K31/401 , A61K31/4422 , A61K31/52 , A61K31/522 , A61K31/616 , A61K9/209 , A61K9/2095 , A61K9/2893 , B30B11/14 , B30B11/16 , B30B11/18 , B30B11/34 , B30B15/308 , A61J2200/20
摘要： The present invention relates to a process for producing multilayer, solid drug forms for oral or rectal administration, which comprises coextrusion of at least two compositions which in each case comprise a thermoplastic, pharmacologically acceptable polymeric binder which is soluble or swellable in a physiological environment, and at least one of which contains a pharmaceutical active ingredient, and shaping the coextruded multilayer material to the required drug form.
摘要翻译： PCT No.PCT / EP96 / 04601 Sec。 371日期：1998年4月15日 102（e）日期1998年4月15日PCT 1996年10月23日PCT公布。公开号WO97 / 15293 日期1997年5月1日本发明涉及用于口服或直肠给药的多层固体药物形式的制备方法，其包括共挤出至少两种组合物，每种组合物在每种情况下都包含热塑性，药理学上可接受的聚合物粘合剂，其可溶于或溶胀于生理环境，并且其中至少一个含有药物活性成分，并将共挤出的多层材料成形为所需的药物形式。

7. 发明授权

US06291579B1 Aqueous powder-paint dispersion 失效
标题翻译：水性粉末涂料分散体
公开(公告)号：US06291579B1
公开(公告)日：2001-09-18
申请号：US09331271
申请日：1999-07-27
申请人： Ulrich Kalck , Joachim Woltering , Maximilian Bendix , Heike Schuchmann , Klaus Borho , Werner Weinle , Michael Schiessl , Sven Rück , Markus Antonietti
发明人： Ulrich Kalck , Joachim Woltering , Maximilian Bendix , Heike Schuchmann , Klaus Borho , Werner Weinle , Michael Schiessl , Sven Rück , Markus Antonietti
IPC分类号： C08L3106
CPC分类号： C08G18/0866 , C08G2150/20 , C09D5/02 , C09D163/00 , C09D175/04
摘要： The invention relates to a process for preparing an aqueous powder coating dispersion, which comprises introducing a liquid melt comprising binders and crosslinking agents and also, if desired, catalysts, auxiliaries and further additives such as devolatilizers, UV absorbers, free-radical scavengers and/or antioxidants into an emulsifying apparatus, preferably with the addition of water and stabilizers, and cooling and filtering the resultant emulsion.
摘要翻译：本发明涉及一种制备水性粉末涂料分散体的方法，该方法包括引入包含粘合剂和交联剂的液体熔体，以及如果需要，引入催化剂，助剂和其它添加剂，例如脱挥发分剂，UV吸收剂，自由基清除剂和/ 或抗氧化剂加入乳化装置中，优选加入水和稳定剂，并冷却和过滤所得乳液。

8. 发明授权

US5905096A Continuous production process of expandable styrene polymer beads 失效
标题翻译：可膨胀苯乙烯聚合物珠粒的连续生产工艺
公开(公告)号：US5905096A
公开(公告)日：1999-05-18
申请号：US391
申请日：1998-01-29
申请人： Peter Nikolaus Lay , Swen Ruck , Michael Schiessl , Michael Witt , Hans Dieter Zettler , Michael Baumgartel , Gerhard Dembek , Klaus Hahn , Jan Holoch , Wolfram Husemann , Knut Kaempfer
发明人： Peter Nikolaus Lay , Swen Ruck , Michael Schiessl , Michael Witt , Hans Dieter Zettler , Michael Baumgartel , Gerhard Dembek , Klaus Hahn , Jan Holoch , Wolfram Husemann , Knut Kaempfer
IPC分类号： C08J9/16 , B01J13/14 , C08F2/02 , C08F2/18 , C08F12/08 , C08J9/18 , C08J9/20
CPC分类号： C08F12/08
摘要： A continuous process for preparing bead-form expandable styrene polymers in which the styrene is prepolymerized in bulk to a conversion of 10 to 80%, the prepolymer is dispersed in liquid form in an aqueous phase in the presence of suspension stabilizers, and the polymerization of the prepolymer is completed in an aqueous suspension to a residual styrene content of less than 2000 ppm.
摘要翻译： PCT No.PCT / EP96 / 03633 371日期1998年1月29日 102（e）1998年1月29日PCT PCT 1996年8月19日PCT公布。公开号WO97 / 08231 日期1997年3月6日一种用于制备珠粒可发性苯乙烯聚合物的连续方法，其中将苯乙烯本体预聚合至10至80％的转化率，预聚物在悬浮稳定剂存在下以液态分散在水相中，并且预聚物的聚合在水悬浮液中完成至小于2000ppm的残余苯乙烯含量。

9. 发明授权

US6051253A Production of solid drug forms 失效
标题翻译：生产固体药物形式
公开(公告)号：US6051253A
公开(公告)日：2000-04-18
申请号：US886286
申请日：1997-07-01
申请人： Hans Dieter Zettler , Michael Schiessl , Jorg Breitenbach , Joerg Rosenberg
发明人： Hans Dieter Zettler , Michael Schiessl , Jorg Breitenbach , Joerg Rosenberg
IPC分类号： A61J3/10 , A61J3/06 , A61K9/20 , B30B11/22
CPC分类号： B30B11/227 , A61J3/06 , A61K9/2095 , B30B11/22 , A61J2200/20
摘要： Solid drug forms are produced by mixing and melting at least one pharmacologically acceptable polymeric binder and at least one pharmaceutical active ingredient, with or without conventional pharmaceutical additives, in the absence of a solvent to give a plastic mixture and shaping the mixture to the required drug form by extrusion, where the shaping takes place in two steps, with the extrudate being broken into shaped articles in a first step, and these shaped articles being rounded off in a second step in the plastic state.
摘要翻译：固体药物形式通过在不存在溶剂的情况下混合和熔化至少一种药理学上可接受的聚合物粘合剂和至少一种药物活性成分（含或不含常规药物添加剂）以产生塑料混合物并将混合物成形为所需药物通过挤出形成，其中成型在两个步骤中进行，挤出物在第一步骤中被破碎成成型制品，并且这些成形制品在塑性状态的第二步骤中被倒圆。

10. 发明授权

US5081270A Preparation of hydroxyanthraquinones 失效
标题翻译：羟基四氢呋喃的制备
公开(公告)号：US5081270A
公开(公告)日：1992-01-14
申请号：US599975
申请日：1990-10-19
申请人： Juergen Pfister , Michael Schiessl , Rainer Nachtrab
发明人： Juergen Pfister , Michael Schiessl , Rainer Nachtrab
IPC分类号： B01J27/08 , B01J19/20 , C07B61/00 , C07C46/00 , C07C46/02 , C07C50/34 , C07C50/38
CPC分类号： C07C50/38 , B01J19/20 , C07C46/00 , C07C50/34
摘要： 1-Hydroxyanthraquinones are prepared in an improved process by reacting phthalic anhydride or derivatives thereof with phenol derivatives in the presence of a Lewis acid as catalyst and in the presence or absence of a diluent, wherein the improvement comprises conducting the reaction in a self-cleaning apparatus having a mixing effect, at a temperature of from 120.degree. C. to 300.degree. C. for from 5 to 1,000 seconds, the self-cleaning apparatus having a mixing effect subjecting the reactants to a shear gradient of from 50 to 20,000 sec.sup.-1 with an energy input of from 0.01 to 0.2 kwh/kg of reactants.
摘要翻译：通过邻苯二甲酸酐或其衍生物与苯酚衍生物在路易斯酸作为催化剂的存在下和在存在或不存在稀释剂的情况下反应制备1-羟基蒽醌，其中改进包括在自清洁中进行反应具有混合效果的装置，在120℃至300℃的温度下为5至1,000秒，所述自清洁装置具有将反应物的剪切梯度为50至20,000秒的混合效果， 1，能量输入为0.01至0.2千瓦时/ kg的反应物。

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