专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2011112082A1 STERILE ALGINATE-BASED AQUEOUS COMPOSITION FOR MEDICAL USE AND PROCESS FOR THE PREPARATION THEREOF 审中-公开
标题翻译：用于医疗用途的基于ALT的碱性水性组合物及其制备方法
公开(公告)号：WO2011112082A1
公开(公告)日：2011-09-15
申请号：PCT/NL2011/050160
申请日：2011-03-08
申请人： BENDER ANALYTICAL HOLDING B.V. , BENDER, Johannes Caspar Mathias Elizabeth , PELLIKAAN, Hubert Clemens
发明人： BENDER, Johannes Caspar Mathias Elizabeth , PELLIKAAN, Hubert Clemens
IPC分类号： A61K31/734
CPC分类号： A61K31/734 , A61K9/0024 , A61K47/02 , A61K47/36
摘要： The present invention relates to ready-to-use sterile, alginate-based, aqueous compositions for medical use. More particularly, the invention relates to an aqueous composition for medical use that has been sterilized by heat sterilization and having a viscosity at 25 ºC of at least 300 cP (Helipath® T F spindle, 100 rpmat 25 °C), said composition having a pH in the range of 6.5-7.5; containing 0.5-10 wt.% of an alginate salt; and further containing 10-500 mM of one or more dissolved C 2 -C 7 mono-or dicarboxylates that are optionally substituted with up to 2 hydroxyl groups. The alginate-based composition of the present invention has excellent storage stability and is easy to manufacture. The alginate-based aqueous compositions of the present invention can advantageously be used, for instance, to prevent adhesions between a healing trauma site and adjacent surrounding tissue. These compositions can further be used in implants or in pharmaceutical preparations for oral administration.
摘要翻译：本发明涉及用于医疗用途的即用型无菌藻酸盐基水性组合物。更具体地说，本发明涉及用于医疗用途的水性组合物，其已经通过热灭菌灭菌，并且在25℃下的粘度为至少300cP（Helipath？TF锭子，25 rpm，100 rpm），所述组合物具有pH 在6.5-7.5的范围内; 含有0.5-10重量％的藻酸盐; 并进一步含有10-500mM的一个或多个可任选被至多2个羟基取代的溶解的C 2 -C 7单或二羧酸酯。本发明的基于藻酸盐的组合物具有优异的储存稳定性，易于制造。本发明的藻酸盐基水性组合物可以有利地用于例如防止愈合创伤部位和相邻的周围组织之间的粘连。这些组合物还可以用于植入物或用于口服给药的药物制剂中。

2. 发明公开

EP2544695A1 STERILE ALGINATE-BASED AQUEOUS COMPOSITION FOR MEDICAL USE AND PROCESS FOR THE PREPARATION THEREOF 有权转让
标题翻译：基于用于医疗用途以及其用于制备方法的含水组合物的无菌藻
公开(公告)号：EP2544695A1
公开(公告)日：2013-01-16
申请号：EP11708587.8
申请日：2011-03-08
申请人： Bender Analytical Holding B.V.
发明人： BENDER, Johannes Caspar Mathias Elizabeth , PELLIKAAN, Hubert Clemens
IPC分类号： A61K31/734
CPC分类号： A61K31/734 , A61K9/0024 , A61K47/02 , A61K47/36
摘要： The present invention relates to ready-to-use sterile, alginate-based, aqueous compositions for medical use. More particularly, the invention relates to an aqueous composition for medical use that has been sterilized by heat sterilization and having a viscosity at 25 ºC of at least 300 cP (Helipath® T F spindle, 100 rpmat 25 °C), said composition having a pH in the range of 6.5-7.5; containing 0.5-10 wt.% of an alginate salt; and further containing 10-500 mM of one or more dissolved C
2 -C
7 mono-or dicarboxylates that are optionally substituted with up to 2 hydroxyl groups. The alginate-based composition of the present invention has excellent storage stability and is easy to manufacture. The alginate-based aqueous compositions of the present invention can advantageously be used, for instance, to prevent adhesions between a healing trauma site and adjacent surrounding tissue. These compositions can further be used in implants or in pharmaceutical preparations for oral administration.

3. 发明授权

EP2544695B1 STERILE ALGINATE-BASED AQUEOUS COMPOSITION FOR MEDICAL USE AND PROCESS FOR THE PREPARATION THEREOF 有权转让
标题翻译：基于用于医疗用途以及其用于制备方法的含水组合物的无菌藻
公开(公告)号：EP2544695B1
公开(公告)日：2015-01-07
申请号：EP11708587.8
申请日：2011-03-08
申请人： Bender Analytical Holding B.V.
发明人： BENDER, Johannes Caspar Mathias Elizabeth , PELLIKAAN, Hubert Clemens
IPC分类号： A61K31/734 , A61K9/00 , A61K47/02 , A61K47/36
CPC分类号： A61K31/734 , A61K9/0024 , A61K47/02 , A61K47/36

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式