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1. 发明申请

US20120321699A1 METHOD OF INDUCING THE PRODUCTION OF PROTECTIVE ANTI-HIV-1 ANTIBODIES 审中-公开
标题翻译：诱导产生抗HIV-1抗体的方法
公开(公告)号：US20120321699A1
公开(公告)日：2012-12-20
申请号：US13581157
申请日：2011-02-25
申请人： Barton F. Haynes , Hua-Xin Liao , Georgia Tomaras , Thomas B. Kepler , Kwan-Ki Hwang , S.Munir Alam , Yang Liu , T. Matt Holl , Guang Yang , Garnett Kelsoe , Mattia Bonsignori
发明人： Barton F. Haynes , Hua-Xin Liao , Georgia Tomaras , Thomas B. Kepler , Kwan-Ki Hwang , S.Munir Alam , Yang Liu , T. Matt Holl , Guang Yang , Garnett Kelsoe , Mattia Bonsignori
IPC分类号： A61K39/21 , A61K9/127 , C07K16/10 , A61P31/18
CPC分类号： A61K39/21 , A61K39/0005 , A61K39/0258 , A61K2039/53 , A61K2039/58 , C07K16/1063 , C12N2740/16034 , C12N2740/16134
摘要： The present invention relates, in general, to an immunogen for HIV vaccination and, in particular, to a method of inducing the production of protective anti-HIV antibodies by targeting B cell germline and clone intermediates using a combination of HIV envelope and non-HIV immunogens. The invention also relates to compositions suitable for use in such a method.
摘要翻译：本发明一般涉及用于HIV疫苗接种的免疫原，特别涉及通过使用HIV包膜和非HIV的组合靶向B细胞种系和克隆中间体来诱导产生保护性抗HIV抗体的方法免疫原。本发明还涉及适用于这种方法的组合物。

2. 发明授权

US09899160B2 Low-profile electronic circuit breakers, systems, and methods 有权
公开(公告)号：US09899160B2
公开(公告)日：2018-02-20
申请号：US13969768
申请日：2013-08-19
申请人： John DeBoer , Brian Timothy McCoy , Guang Yang
发明人： John DeBoer , Brian Timothy McCoy , Guang Yang
IPC分类号： H01H9/54 , H01H11/00 , H02J4/00 , H01H71/02 , H01H71/10 , H01H71/12
CPC分类号： H01H9/54 , H01H11/00 , H01H71/0271 , H01H71/1045 , H01H71/12 , H02B1/056 , H02J4/00 , Y10T29/49105
摘要： A low-profile electronic circuit breaker includes first and second electrical branches coupled to respective first and second load terminals. The electronic circuit breaker also includes an electronic processing circuit configured to monitor an electrical condition in the first and second electrical branches. The electronic circuit breaker is packaged in a housing sized to occupy a standard single-pole breaker panelboard location. In some embodiments, the electronic circuit breaker has no load neutral terminals associated with the first and second load terminals. Methods of assembling an electronic circuit breaker are provided, as are other system and method aspects.

3. 发明授权

US09458437B2 Neuroprotective peptides that inhibit interaction between palmitoyl acyl transferase zinc-finger DHHC type containing 17 (zD17) and c-jun N-terminal kinase (JNK) 有权
标题翻译：抑制与含有17（zD17）和c-jun N-末端激酶（JNK）的棕榈酰酰基转移酶锌指DHHC型相互作用的神经保护肽
公开(公告)号：US09458437B2
公开(公告)日：2016-10-04
申请号：US14232268
申请日：2012-07-12
申请人： Max S. Cynader , Guang Yang
发明人： Max S. Cynader , Guang Yang
IPC分类号： A61K38/45 , C07K19/00 , C12N9/10 , A61K47/48 , A61K38/00
CPC分类号： C12N9/1029 , A61K38/00 , A61K38/45 , A61K47/48315 , A61K47/645 , C07K2319/10 , C07K2319/23 , C07K2319/41 , C07K2319/70
摘要： Isolated polypeptides are disclosed herein, the isolated polypeptides comprising at least 90% identity to any one of: SEQ ID NO:1; SEQ ID NO:2; or SEQ ID NO:3, wherein the isolated polypeptide inhibits an interaction between palmitoyl acyl transferase zinc-finger DHHC type containing 17 (z D17) and c-jun N-terminal kinase (JNK). The polypeptides may be conjugated to a delivery and targeting moiety, such as the cell-membrane transduction domain of the HIV-1 Tat protein. There are also provided methods for treating a disease associated with cytotoxicity or excitotoxicity.
摘要翻译：本文公开了分离的多肽，所述分离的多肽与SEQ ID NO：1中的任一个包含至少90％的同一性; SEQ ID NO：2; 或SEQ ID NO：3，其中所述分离的多肽抑制含有17（z D17）和c-jun N-末端激酶（JNK）的棕榈酰酰基转移酶锌指DHHC型之间的相互作用。多肽可以与递送和靶向部分缀合，例如HIV-1 Tat蛋白的细胞膜转导结构域。还提供了治疗与细胞毒性或兴奋性毒性相关的疾病的方法。

4. 发明授权

US09021061B2 Method and apparatus for accommodating overlapping wireless networks 有权
标题翻译：用于容纳重叠的无线网络的方法和装置
公开(公告)号：US09021061B2
公开(公告)日：2015-04-28
申请号：US12643037
申请日：2009-12-21
申请人： Guang Yang
发明人： Guang Yang
IPC分类号： G06F15/16 , H04L29/12
CPC分类号： H04L29/12594 , H04L61/303 , H04M2250/06
摘要： A method comprises forming a pathname indicative of a location of content on a wireless network, the pathname including an identifier of the wireless network; and sending a request for the content, the request including the pathname. In one embodiment, the pathname further includes a delimiter configured to specify a location of the identifier of the wireless network in the pathname.
摘要翻译：一种方法包括：在无线网络上形成指示内容位置的路径名，路径名包括无线网络的标识符; 并发送对内容的请求，该请求包括路径名。在一个实施例中，路径名还包括分配符，其被配置为指定路径名中的无线网络的标识符的位置。

5. 发明授权

US08856226B2 Method, apparatus, and computer program product for context-based contact information management 有权
标题翻译：用于基于上下文的联系信息管理的方法，设备和计算机程序产品
公开(公告)号：US08856226B2
公开(公告)日：2014-10-07
申请号：US12362956
申请日：2009-01-30
申请人： Peter Boda , Guang Yang
发明人： Peter Boda , Guang Yang
IPC分类号： G06F15/16 , H04M3/42
CPC分类号： H04M3/42 , H04M2201/36 , H04M2203/2038
摘要： An apparatus for context-based contact information management may include a processor. The processor may be configured to receive contact information and associated sender-based context information. In this regard, the contact information and sender-based context information may have been transmitted from a sending device. The processor may also be configured to associate receiver-based context information with the contact information and identify a historical context within a historical multi-dimensional context environment based at least in part on the sender-based context information and the receiver-based context information. Further, the processor may be configured to link the contact information to the historical context. Associated methods and computer program products may also be provided.
摘要翻译：用于基于上下文的联系人信息管理的装置可以包括处理器。处理器可以被配置为接收联系人信息和相关联的基于发送者的上下文信息。在这方面，可以从发送设备发送联系人信息和基于发送者的上下文信息。处理器还可以被配置为将基于接收者的上下文信息与联系信息相关联，并且至少部分地基于基于发送者的上下文信息和基于接收者的上下文信息来识别历史多维上下文环境中的历史上下文。此外，处理器可以被配置为将联系人信息链接到历史上下文。还可以提供相关方法和计算机程序产品。

6. 发明授权

US08787386B2 Systems and methods for creating composed communication services 有权
标题翻译：创建组合通信服务的系统和方法
公开(公告)号：US08787386B2
公开(公告)日：2014-07-22
申请号：US13277968
申请日：2011-10-20
申请人： Kirankumar Nimashakavi , Ming Yin , Guang Yang
发明人： Kirankumar Nimashakavi , Ming Yin , Guang Yang
IPC分类号： H04L12/28 , H04L12/54 , H04L12/24 , H04L12/56 , H04W4/02 , H04W4/12 , H04W28/24
CPC分类号： H04L12/5695 , G06Q10/10 , G06Q50/32 , H04L12/2876 , H04L41/5003 , H04L41/5006 , H04L41/5009 , H04L41/5019 , H04L41/5022 , H04L41/5041 , H04L47/10 , H04L47/29 , H04L47/70 , H04L47/824 , H04L51/10 , H04L51/38 , H04L67/2838 , H04M3/42382 , H04W4/02 , H04W4/12 , H04W4/16 , H04W28/24
摘要： Systems and methods are described for creating composed communication services within a gateway to a telecom network. Composed communication services are virtual services which can be created by a network operator and which combine two or more actual communication services that perform functionality in the telecom network. For example, a composed messaging service can be created for a client, which combines methods from the MMS and SMS communication services. Subsequently, when the client invokes either SMS or MMS services in the gateway, those invocations will be counted against the composed service and the SLA and policy control will be applied against it accordingly.
摘要翻译：描述了用于在到电信网络的网关内创建组合通信服务的系统和方法。组合的通信服务是可由网络运营商创建并且组合在电信网络中执行功能的两个或多个实际通信服务的虚拟服务。例如，可以为客户端创建组合的消息服务，其结合来自MMS和SMS通信服务的方法。随后，当客户端在网关中调用SMS或MMS服务时，这些调用将被计入对组合的服务，SLA和策略控制将相应地应用于该服务。

7. 发明授权

US08719774B2 Developing programs for hardware implementation in a graphical specification and constraint language Via iterative estimation of performance or resource utilization 有权
标题翻译：在图形规范和约束语言中开发用于硬件实现的程序通过对性能或资源利用率的迭代估计
公开(公告)号：US08719774B2
公开(公告)日：2014-05-06
申请号：US13193366
申请日：2011-07-28
申请人： Guoqiang Wang , Jeffrey N. Correll , Sadia B. Malik , Hugo A. Andrade , Newton G. Petersen , Rhishikesh Limaye , Trung N. Tran , Jacob Kornerup , Kaushik Ravindran , Guang Yang
发明人： Guoqiang Wang , Jeffrey N. Correll , Sadia B. Malik , Hugo A. Andrade , Newton G. Petersen , Rhishikesh Limaye , Trung N. Tran , Jacob Kornerup , Kaushik Ravindran , Guang Yang
IPC分类号： G06F9/44
CPC分类号： G06F8/20 , G06F3/048 , G06F8/34 , G06F9/44 , G06F9/4494 , G06F17/30294 , G06F17/30572 , G06F17/5004 , G06F17/5045 , G06F2217/02 , G06F2217/04 , G06F2217/06 , G06F2217/12 , G06F2217/14 , G06F2217/16 , G06F2217/74
摘要： System and method for specifying and implementing programs. A graphical program is created in a graphical specification and constraint language that allows specification of a model of computation and explicit declaration of constraints in response to user input. The graphical program includes a specified model of computation, a plurality of interconnected functional blocks that visually indicate functionality of the graphical program in accordance with the specified model of computation, and specifications or constraints for the graphical program or at least one of the functional blocks in the graphical program. The specified model of computation and specifications or constraints are useable to analyze the graphical program or generate a program or simulation.
摘要翻译：用于指定和实现程序的系统和方法。以图形规范和约束语言创建图形程序，该语言允许指定计算模型并响应用户输入显式声明约束。图形程序包括指定的计算模型，多个互连的功能块，其可视地指示根据指定的计算模型的图形程序的功能，以及用于图形程序或至少一个功能块的规格或约束图形程序。指定的计算模型和规范或约束可用于分析图形程序或生成程序或模拟。

8. 发明申请

US20130303184A1 STATE CHANGE SENSING BASED ON INDIVIDUAL LOCATION PATTERNS 有权
标题翻译：基于个人定位模式的状态变化感知
公开(公告)号：US20130303184A1
公开(公告)日：2013-11-14
申请号：US13825364
申请日：2010-09-23
申请人： Guang Yang , Du Li , Yifei Jiang , Zhigang Liu
发明人： Guang Yang , Du Li , Yifei Jiang , Zhigang Liu
IPC分类号： H04W8/22 , H04W64/00
CPC分类号： H04W8/22 , G01S5/0263 , G01S19/48 , H04W64/006
摘要： A system for detecting state transitions when apparatuses move between significant places or routes without having to employ high resolution, and high energy cost, localization technologies. Apparatuses may receive position information via lower resolution/lower energy cost localization resources, and this information may be used to determine whether the current position of the apparatus corresponds to a significant place or route. If the apparatus is determined to be positioned in a significant place or route, a further determination may be made as to whether at least one second level classifier exists for the significant place or route. Second level classifiers may be utilized to determine when apparatuses transition from one state (e.g., one significant place or route) to another. Upon detection of a state transition based on the second level classifier, a new localization configuration may be applied in the apparatus.
摘要翻译：用于当装置在重要位置或路线之间移动时检测状态转换的系统，而不必采用高分辨率和高能量成本的定位技术。设备可以通过较低分辨率/较低的能量成本定位资源来接收位置信息，并且该信息可用于确定设备的当前位置是否对应于重要的位置或路线。如果确定设备被定位在重要的位置或路线上，则可以进一步确定是否存在用于重要地方或路线的至少一个二级分类器。可以利用第二级分类器来确定装置何时从一个状态（例如，一个有效位置或路线）转换到另一个状态。在检测到基于第二级分类器的状态转换时，可以在该装置中应用新的定位配置。

9. 发明授权

US08563882B2 Electronic circuit breaker having a locking and unlocking mechanism and methods of operating same 有权
标题翻译：具有锁定和解锁机构的电子断路器及其操作方法
公开(公告)号：US08563882B2
公开(公告)日：2013-10-22
申请号：US13267953
申请日：2011-10-07
申请人： Guang Yang
发明人： Guang Yang
IPC分类号： H01H9/28
CPC分类号： H01H71/46 , H01H71/505
摘要： Embodiments provide an electronic circuit breaker. The electronic circuit breaker has main electrical contacts configurable between an opened and a closed condition, a handle coupled to at least one of the main electrical contacts, the handle moveable between at least an ON configuration and an OFF configuration, secondary electrical contacts configured to engage each other in the ON configuration, and a moveable stop operable to maintain separation of the main electrical contacts initially when moved toward the ON configuration, and operable to unlock and allow closing of the main electrical contacts upon successful completion of a self-test. A method of operating the electronic circuit breaker is provided, as are other aspects.
摘要翻译：实施例提供一种电子断路器。电子断路器具有可在打开和关闭状态之间配置的主电气触头，与至少一个主电触点相连的手柄，可在至少ON配置和OFF配置之间移动的手柄，辅助电触点被配置为接合 ON配置中的另一个，以及可移动停止器，其可操作以在移动朝向ON配置时保持主电触头的分离，并且可以在成功完成自检时操作以解锁并允许关闭主电触点。与其他方面一样，提供了操作电子断路器的方法。

10. 发明申请

US20130265994A1 Information feedback method and device for uplink closed loop transmission diversity 审中-公开
标题翻译：用于上行链路闭环传输分集的信息反馈方法和装置
公开(公告)号：US20130265994A1
公开(公告)日：2013-10-10
申请号：US13909053
申请日：2013-06-03
申请人： Junqiang Liu , Guang Yang , Chi Zhang , Shuhui Liu , Yongyu Chang
发明人： Junqiang Liu , Guang Yang , Chi Zhang , Shuhui Liu , Yongyu Chang
IPC分类号： H04W72/04
CPC分类号： H04W72/0413 , H04B7/0404 , H04B7/0456 , H04B7/0613 , H04B7/0619 , H04W52/146 , H04W52/42 , H04W52/54 , H04W52/58
摘要： The present disclosure discloses an information feedback method for uplink closed loop transmission diversity, which includes: a base station allocates each Fractional Dedicated Physical Channel (F-DPCH) to at least one user; and the base station takes at least one F-DPCH as a feedback channel and arranges information of different users in each said F-DPCH by time division multiplexing, wherein information of at least one user in the F-DPCH includes feedback information of the uplink closed loop transmission diversity and an uplink Transmission Power Control (TPC) command. The present disclosure further discloses an information feedback device for uplink closed loop transmission diversity. Through the solution of the present disclosure, information feedback of the uplink closed loop transmission diversity can be implemented, when the information is a weight, the problem of weight feedback of the uplink closed loop transmission diversity is solved, and a user side of a High Speed Uplink Packet Access (HSUPA) system is facilitated to complete an operation of transmission diversity.
摘要翻译：本公开公开了一种用于上行链路闭环发送分集的信息反馈方法，其包括：基站将每个分数专用物理信道（F-DPCH）分配给至少一个用户; 并且基站将至少一个F-DPCH作为反馈信道，并且通过时分多路复用在每个所述F-DPCH中排列不同用户的信息，其中F-DPCH中的至少一个用户的信息包括上行链路的反馈信息闭环传输分集和上行传输功率控制（TPC）命令。本公开还公开了一种用于上行链路闭环发射分集的信息反馈装置。通过本公开的解决方案，可以实现上行链路闭环发送分集的信息反馈，当信息是权重时，解决了上行链路闭环发送分集的权重反馈的问题，并且用户侧的高快速上行链路分组接入（HSUPA）系统有助于完成传输分集的操作。

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