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    • 6. 发明申请
    • Flow cell for optical detection having reduced sensitivity to refractive index variation
    • 用于光学检测的流动池具有降低的对折射率变化的敏感性
    • US20050094158A1
    • 2005-05-05
    • US10700947
    • 2003-10-31
    • Barbara PaldusAlexander KatchanovRobert Lodenkamper
    • Barbara PaldusAlexander KatchanovRobert Lodenkamper
    • G01N21/39G01B9/02
    • G01N21/39
    • An apparatus for cavity enhanced optical detection comprising: a) a source of optical radiation b) a resonant optical cavity which provides a round trip path for said optical radiation the cavity comprising: i) a plurality of mirrors, the first mirror being an input mirror which receives the optical radiation and inputs it into the cavity; ii) a flow cell positioned within said cavity, said flow cell comprising at least a first analysis channel which accommodates a flow of analyte fluid there through, iii) a second mirror, which second mirror receives the radiation from the optical source after its passage through both said input mirror and said analysis channel and reflects said received radiation. The resonant optical cavity provides a round trip path for analyte fluid having at least two different refractive index values and the location of the point at which said reflected radiation impinges on said input mirror remains substantially the same as the point from which said first mirror inputs said radiation into said cavity notwithstanding changes in the refractive index of the analyte fluid or the wavelength of the optical radiation.
    • 一种用于空腔增强光学检测的装置,包括:a)光辐射源; b)谐振光学腔,其为所述光辐射提供所述光辐射的往返路径,所述光腔包括:i)多个反射镜,所述第一反射镜是输入镜 其接收光辐射并将其输入到腔中; ii)位于所述空腔内的流动池,所述流动池包括至少第一分析通道,其容纳其中通过的分析物流体流,iii)第二反射镜,所述第二反射镜在其通过之后接收来自光源的辐射 所述输入反射镜和所述分析通道都反映所述接收的辐射。 谐振光学腔提供具有至少两个不同折射率值的分析物流体的往返路径,并且所述反射辐射照射在所述输入反射镜上的点的位置保持与所述第一反射镜从其输入所述输入反射镜的点大致相同 尽管分析物流体的折射率或光辐射的波长发生变化,但是辐射进入所述腔。
    • 10. 发明授权
    • Method for detecting a gaseous analyte present as a minor constituent in an admixture
    • 用于检测在混合物中作为次要成分存在的气态分析物的方法
    • US07265842B2
    • 2007-09-04
    • US10966314
    • 2004-10-14
    • Barbara PaldusBruce RichmanAlexander KachanovEric Crosson
    • Barbara PaldusBruce RichmanAlexander KachanovEric Crosson
    • G01J5/02G01J1/42G01N21/00
    • G01N21/39
    • A gaseous target analyte present as a minor constituent in an admixture with at least one other gaseous species can be detected using a cavity enhanced optical spectrometer by a process comprising the steps of: i) identifying a plurality of strong spectral absorption peaks of the target analyte which are present within the scanning range of the spectrometer, ii) determining for the identified peaks the pressure region above which the peak width increases substantially with increasing pressure and below which the peak width is substantially independent of pressure, iii) determining which of the peaks identified in step i) are, within the pressure region determined in step ii), free from spectral interference by any of the other components of the admixture. iv) measuring the spectrum of the admixture at the pressure region identified in step ii).
    • 可以使用空腔增强型光谱仪通过包括以下步骤的方法检测与至少一种其它气态物质混合物中作为次要成分存在的气态目标分析物:i)鉴定目标分析物的多个强光谱吸收峰 它们存在于光谱仪的扫描范围内,ii)确定所识别的峰的压力区域,在该压力区域上,峰宽度随着压力的增加而基本上增加并且低于该压力峰值宽度基本上与压力无关,iii)确定哪个峰值 在步骤i)中确定的压力区域在步骤ii)中确定的压力区域内,不受混合物中任何其它组分的光谱干扰。 iv)测量在步骤ii)中鉴定的压力区域上的混合物的光谱。