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1. 发明申请

WO1995015324A1 SUBSTITUTED AMINOALKYLAMINOPYRIDINES 审中-公开
标题翻译：取代AMINOALKYLAMINOPYRIDINE
公开(公告)号：WO1995015324A1
公开(公告)日：1995-06-08
申请号：PCT/EP1994003911
申请日：1994-11-26
申请人： BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH , SENN-BILFINGER, Jörg
发明人： BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH , KOHL, Bernhard , GRUNDLER, Gerhard , OPFERKUCH, Wolfgang
IPC分类号： C07D401/12
CPC分类号： C07D401/12 , C07D401/14 , C07D405/14 , C07D471/04
摘要： Compounds of formula (I) where R1, R2, R3, R4, R5, R6, X, n and A are as indicated in the description, can be used for combatting Helicobacter bacteria.
摘要翻译：式（I）化合物其中R1，R2，R3，R4，R5，R6，X，n和A具有说明书中给出的含义，是适合于螺杆菌的控制。

2. 发明申请

WO1989000570A1 NEW DIAZOLS 审中-公开
标题翻译：新的DIAZOLS
公开(公告)号：WO1989000570A1
公开(公告)日：1989-01-26
申请号：PCT/EP1988000638
申请日：1988-07-14
申请人： BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH , SENN-BILFINGER, Jörg
发明人： BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH , GRUNDLER, Gerhard , SCHAEFER, Hartmann , KLEMM, Kurt , RAINER, Georg , SCHUDT, Christian , SIMON, Wolfgang-Alexander , RIEDEL, Richard , POSTIUS, Stefan
IPC分类号： C07D471/04
CPC分类号： C07D471/04 , C07D487/04
摘要： Compounds of formula (I) in which R1 is H or halogen, R2 is H, alkyl, hydroxyalkyl, haloalkyl, cyanoalkyl or alkoxycarbonyl, R3 is H, alkyl, formyl, hydroxyalkyl, haloalkyl, cyanoalkyl, aminoalkyl, mono- or dialkylaminoalkyl, nitroso, nitro, amino, mono- or dialkylamino or alkoxycarbonyl, R4 is H, alkyl, alkoxy, halogen or trifluoromethyl, R5 is H, alkyl, alkoxy, halogen or trifluoromethyl, R6 is hydrogen or alkyl, n is 1 or 2, G1 is CH or N, G2 is O, NH, N-alkyl or alkylene, G3 is (-CH(OH)-CH2-CH2-), (-CH2-CH(OH)-CH(CH3)-), (-CH2-CH(OH)-CH2-), (-CH(OH)-CH2-CH2-CH2-), (-CH2-CH(OH)-CH2-CH2-), (-CH(OH)-CH2-CH2-CH2-CH2-) (-CH2-CH(OH)-CH2-CH2-CH2-), and G4 is S, O or (-CH=CH-). These compounds have attractive pharmacological properties. They have, in particular, a remarkable protective effect on the stomach and intestines in warm-blooded beings.
摘要翻译：式（I）化合物，其中R 1是H或卤素，R 2是H，烷基，羟基烷基，卤代烷基，氰基烷基或烷氧基羰基，R 3是H，烷基，甲酰基，羟基烷基，卤代烷基，氰基烷基，氨基烷基，单或二烷基氨基烷基，亚硝基，硝基，氨基，一或二烷基氨基或烷氧基羰基，R 4是H，烷基，烷氧基，卤素或三氟甲基，R 5是H，烷基，烷氧基，卤素或三氟甲基，R 6是氢或烷基，n是1或2， CH或N，G 2是O，NH，N-烷基或亚烷基，G 3是（-CH（OH）-CH 2 -CH 2 - ），（-CH 2 -CH（OH）-CH（CH 3） -CH（OH）-CH 2 - ），（-CH（OH）-CH 2 -CH 2 -CH 2 - ），（-CH 2 -CH（OH）-CH 2 -CH 2 - ），（-CH（OH） -CH 2 -CH 2 - ）（-CH 2 -CH（OH）-CH 2 -CH 2 -CH 2 - ），而G4是S，O或（-CH = CH-）。这些化合物具有诱人的药理特性。他们特别对温血生物对胃肠有显着的保护作用。

3. 发明申请

WO1988008843A2 NEW IMIDAZOLS 审中-公开
标题翻译：新IMIDAZOLS
公开(公告)号：WO1988008843A2
公开(公告)日：1988-11-17
申请号：PCT/EP1988000368
申请日：1988-05-04
申请人： BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH , SENN-BILFINGER Jörg
发明人： BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH , GRUNDLER, Gerhard , SHAEFER, Hartmann , KLEMM, Kurt , RAINER, Georg , RIEDEL, Richard , SCHUDT, Christian , SIMON, Wolfgang
IPC分类号： C07D471/04
CPC分类号： C07D471/04 , C07D487/04
摘要： Compounds of formula (I), in which R1 is H, halogen, alkyl, alkoxy, alkoxycarbonyl or cyanogen; R2 is H, alkyl, hydroxyalkyl, haloalkyl, cyanoalkyl or alkoxycarbonyl; R3 is H, alkyl, formyl, hydroxyalkyl, haloalkyl, cyanoalkyl, aminoalkyl, mono- or dialkylaminoalkyl, nitroso, nitro, amino, mono- or dialkylamino or alkoxycarbonyl; R4 is H, alkyl, alkoxy, halogen or trifluoromethyl; R5 is H, alkyl, alkoxy, halogen or trifluoromethyl; R6 is H or alkyl; n is 1 or 2; G1 is CH or N; G2 is O, NH, N-alkyl, S, (=CH-) or alkylene; G3 is ethylene, trimethylene, tetramethylene, pentamethylene, propenylene, 1-butenylene or 2-butenylene; G4 is S, O or (-CH=CH-). These compounds have interesting pharmacological properties. They have in particular a protective effect on the stomach and intestines of warm-blooded animals.

4. 发明申请

WO1994024130A1 NEW PYRIDINIUM SALTS AND THEIR USE FOR CONTROLLING HELICOBACTER BACTERIA 审中-公开
标题翻译：新吡啶及其用于防治螺杆菌
公开(公告)号：WO1994024130A1
公开(公告)日：1994-10-27
申请号：PCT/EP1994001218
申请日：1994-04-20
申请人： BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH , SENN-BILFINGER, Jörg
发明人： BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH , GRUNDLER, Gerhard , RAINER, Georg , OPFERKUCH, Wolfgang
IPC分类号： C07D471/04
CPC分类号： C07D471/04
摘要： Compounds having formula (I), in which the substituents and symbols have the meanings given in the description, are useful for controlling helicobacter bacteria.

5. 发明申请

WO1993016693A1 NOVEL AND PRIOR ART DISULPHIDES AND THEIR USE IN THE CONTROL OF HELICOBACTER BACTERIA 审中-公开
标题翻译：新型和现代艺术歧视及其在控制幽门螺杆菌中的应用
公开(公告)号：WO1993016693A1
公开(公告)日：1993-09-02
申请号：PCT/EP1993000398
申请日：1993-02-19
申请人： BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH , SENN-BILFINGER, Jörg , STURM, Ernst
发明人： BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH , GRUNDLER, Gerhard , KOHL, Bernhard , KRÜGER, Uwe , OPFERKUCH, Wolfgang
IPC分类号： A61K31/44
CPC分类号： C07D401/04 , A61K31/44
摘要： Compounds of formula (I) in which the constituents and symbols have the meaning given in the description, are suitable for combatting helicobacter bacteria.
摘要翻译：其中组分和符号具有描述中给出的含义的式（I）化合物适用于对抗幽门螺杆菌。

6. 发明申请

WO1995010518A1 ALKOXY ALKYL CARBAMATES FROM IMIDAZO (1,2-a)PYRIDINES 审中-公开
标题翻译：咪唑并（1,2-a）的吡啶的ALKOXYALKYLCARBAMATE
公开(公告)号：WO1995010518A1
公开(公告)日：1995-04-20
申请号：PCT/EP1994003326
申请日：1994-10-08
申请人： BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH , RAINER, Georg
发明人： BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH , SENN-BILFINGER, Jörg , GRUNDLER, Gerhard , RIEDEL, Richard , POSTIUS, Stefan , SIMON, Wolfgang-Alexander
IPC分类号： C07D417/04
CPC分类号： C07D471/04
摘要： The invention relates to novel compounds of formula (I) and their therapeutic use.
摘要翻译：本发明涉及式（I）和它们的治疗用途的新化合物。

7. 发明申请

WO2002064584A1 PHTHALAYINONE-PIPERIDINO-DERIVATIVES AS PDE4 INHIBITORS 审中-公开
标题翻译：作为PDE4抑制剂的PHTHALAYINONE-PIPERIDINO衍生物
公开(公告)号：WO2002064584A1
公开(公告)日：2002-08-22
申请号：PCT/EP2002/001547
申请日：2002-02-14
申请人： BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH , GRUNDLER, Gerhard , GUTTERER, Beate , STERK, Geert, Jan
发明人： GRUNDLER, Gerhard , GUTTERER, Beate , STERK, Geert, Jan , HATZELMANN, Armin , BUNDSCHUH, Daniela , KLEY, Hans-Peter , TIMMERMAN, Hendrik , CHRISTIAANS, Johannes, A., M.
IPC分类号： C07D401/04
CPC分类号： C07D401/04 , A61K31/502 , C07D401/14 , C07D405/14 , C07D417/14 , C07D487/04 , C07D495/04
摘要： The compounds of a formula I, in which the given substituents have the meanings as given in the description, are novel effective PDE4 inhibitors.
摘要翻译：其中给定的取代基具有如说明书中给出的含义的式I化合物是新的有效的PDE4抑制剂。

8. 发明申请

WO1991011449A1 PROCESS FOR THE PRODUCTION OF THIENOTRICYCLENE 审中-公开
标题翻译：生产三烯丙基苯酚的方法
公开(公告)号：WO1991011449A1
公开(公告)日：1991-08-08
申请号：PCT/EP1991000200
申请日：1991-02-04
申请人： BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH , KOHL, Bernhard
发明人： BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH , GRUNDLER, Gerhard , FIGALA, Volker , ULRICH, Wolf-Rüdiger
IPC分类号： C07D495/04
CPC分类号： C07D495/04
摘要： The invention relates to a novel process for the production of telenzepine enantiomers.

9. 发明申请

WO1990005136A1 NEW IMIDAZOPYRIDINES 审中-公开
标题翻译：新咪唑吡啶
公开(公告)号：WO1990005136A1
公开(公告)日：1990-05-17
申请号：PCT/EP1989001316
申请日：1989-11-03
申请人： BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH , RAINER, Georg
发明人： BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH , SCHAEFER, Hartmann , SENN-BILFINGER, Jörg , GRUNDLER, Gerhard , KLEMM, Kurt , SIMON, Wolfgang-Alexander , RIEDEL, Richard , POSTIUS, Stefan
IPC分类号： C07D471/04
CPC分类号： C07D471/04
摘要： Imidazopyridines of formula (I), where R1 stands for H, alkyl, hydroxyalkyl, haloalkyl, cyanoalkyl or alkoxycarbonyl, R2 stands for H, alkyl, formyl, hydroxyalkyl, haloalkyl, cyanoalkyl or dialkylaminoalkyl, R3 stands for H, alkoxy or halogen, R4 stands for H, alkoxy or halogen and G1 stands for a substituted group of formula -CH(OR5)-CH2-CH2-, -CH2-CH(OR5)-CH(CH3)-, -CH2-CH(OR5)-CH2-, -CH(OR5)-CH2-CH2-CH2-, -CH2-CH(OR5)-CH2-CH2-, -CH(OR5)-CH2-CH2-CH2-CH2- or -CH2-CH(OR5)-CH2-CH2-CH2-, where R5 stands for alkyl, cycloalkyl, alkoxyalkyl, arylalkyl, alkylcarbonyl, cycloalkylcarbonyl, arylalkylcarbonyl, alkoxyalkylcarbonyl, alkoxyalkoxyalkylcarbonyl, alkoxycarbonyl, alkoxyalkoxycarbonyl, arylcarbonyl, furoyl or a carbamoyl group of formula (II), where R6 stands for H, alkyl, hydroxyalkyl or together with R7 and with the nitrogen atom to which they are both linked, pyrrolidino, piperidino, tetrahydroazepino, piperazino, N-methylpiperazino or morpholino, and R7 stands for H, alkyl, aryl or, together with R6 and with the nitrogen atom to which they are both linked, pyrrolidino, piperidino, tetrahydroazepino, piperazino, N-methylpiperazino or morpholino, where aryl stands for phenyl or substituted phenyl with one, two or three substituents from the group halogen, alkyl or alkoxy, are new compounds which protect the stomach and intestines in warm-blooded animals.

10. 发明申请

WO2002094832A1 NEW BENZYLAMINOPYRIMIDINES 审中-公开
标题翻译：新的苯甲酰胺
公开(公告)号：WO2002094832A1
公开(公告)日：2002-11-28
申请号：PCT/EP2002/005266
申请日：2002-05-14
申请人： BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH , GRUNDLER, Gerhard
发明人： GRUNDLER, Gerhard , ZIMMERMANN, Peter , CHIESA, Vittoria , POSTIUS, Stefan , HANAUER, Guido , OPFERKUCH, Wolfgang
IPC分类号： C07D487/04
CPC分类号： C07D403/12 , C07D487/04
摘要： Benzylaminopyrimidine compounds of a certain general formula I, in which the substituents and symbols are as defined in the description, are suitable for controlling Helicobacter bacteria.
摘要翻译：一些通式I的苄基氨基嘧啶化合物，其中取代基和符号如说明书中所定义，适用于控制幽门螺杆菌。

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