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    • 4. 发明申请
    • ORAL CARE REGIMENS AND KITS
    • 口腔护理程序和工具
    • WO2007117498A2
    • 2007-10-18
    • PCT/US2007008377
    • 2007-04-05
    • PROCTER & GAMBLEWHITE DONALD JAMES JRBIESBROCK AARON REED
    • WHITE DONALD JAMES JRBIESBROCK AARON REED
    • A61K8/19A61K8/21A61K8/24A61K8/34A61K8/41A61K8/49A61Q11/00
    • A61K8/21A61K8/19A61K8/22A61K8/24A61K8/27A61K8/347A61K8/416A61K8/43A61K8/4926A61K2800/88A61Q11/00
    • Disclosed are oral hygiene regimens comprising a plurality of steps involving the use of two or more oral care products containing actives effective to provide one or more benefits including cleaning, antimicrobial, antiplaque, anticaries, anti-calculus, anti-demineralizing, anti-erosion, antisensitivity/desensitizing, whitening, surface conditioning, polishing, and pH-balancing, wherein the plurality of steps are conducted and sequenced for maximizing delivery of oral care actives to target surfaces of a subject's oral cavity thereby achieving optimum oral health and hygiene benefits. In one aspect, a regimen comprises at least once daily of each of the following steps: (a) applying an antimicrobial dentifrice to oral cavity surfaces, and (b) rinsing the oral cavity with an antimicrobial mouthrinse, wherein at least one of steps (a) and (b) is conducted prior to retiring at night. Preferably the regimen comprises as step (c) treating interproximal, gingival and subgingival areas of the oral cavity using an interproximal device selected from dental floss, floss pick, dental tape, and proxy brush, wherein step (c) is conducted immediately before or immediately after one or both of steps (a) and (b).
    • 公开了包括多个步骤的口腔卫生方案,所述方法包括使用两种或更多种口服护理产品,所述口腔护理产品含有有效提供一种或多种益处,包括清洁,抗微生物,抗牙垢,防龋齿,抗结石,抗脱盐,抗侵蚀, 反渗透/脱敏,美白,表面调理,抛光和pH平衡,其中对多个步骤进行和测序以最大限度地将口腔护理活性物质递送到受试者口腔的靶表面,从而实现最佳的口腔健康和卫生益处。 一方面,方案包括每天至少一次以下每个步骤:(a)将抗微生物洁牙剂施用于口腔表面,和(b)用抗微生物漱口水冲洗口腔,其中步骤( a)和(b)在晚上退休之前进行。 优选地,方案包括步骤(c)使用选自牙线,牙线剔除,牙带和代理刷的邻间装置治疗口腔的邻间,牙龈和龈下区域,其中步骤(c)在紧接之前或立即进行 在步骤(a)和(b)中的一个或两个之后。