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1. 发明申请

WO2005110696A2 INTRAVASCULAR FILTER MEMBRANE AND METHOD OF FORMING 审中-公开
标题翻译：血管滤过膜及其形成方法
公开(公告)号：WO2005110696A2
公开(公告)日：2005-11-24
申请号：PCT/US2005/011002
申请日：2005-03-31
申请人： BOSTON SCIENTIFIC SCIMED, INC. , SMITH, Mark S. , HANSEN, James G. , CRANK, Justin M. , ANDERSON, Narin , LIN, Horng-Ban
发明人： SMITH, Mark S. , HANSEN, James G. , CRANK, Justin M. , ANDERSON, Narin , LIN, Horng-Ban
IPC分类号： B29C
CPC分类号： B01D69/00 , A61F2/01 , A61F2002/018 , A61F2230/0006 , A61F2230/008 , B01D63/00 , B01D67/002 , B01D69/10 , B01D2323/24
摘要： Intravascular filters formed by a molding process can have a plurality of integrally formed apertures. A molding process can utilize a mold assembly that includes a mold having a mold surface and a die having a die surface. The mold assembly includes plurality of protrusions that extend from at least one of the mold surface and the die surface. A molten material is placed within a portion of the mold, and the die is then inserted into the mold such that the plurality of protrusions span a distance between the die surface and the mold surface. The molten material is allowed to solidify, thereby forming a filter membrane that includes a plurality of integrally formed apertures.
摘要翻译：通过模制过程形成的血管内过滤可以具有多个整体形成的孔。模制工艺可以利用包括具有模具表面的模具和具有模具表面的模具的模具组件。模具组件包括从模具表面和模具表面中的至少一个延伸的多个突起。将熔融材料放置在模具的一部分内，然后将模具插入模具中，使得多个突起跨越模具表面和模具表面之间的距离。允许熔融材料固化，从而形成包括多个整体形成的孔的过滤膜。

2. 发明申请

WO2010065126A2 DEVICES, SYSTEMS AND METHODS FOR DELIVERING FLUID TO TISSUE 审中-公开
标题翻译：用于将流体输送到组织的装置，系统和方法
公开(公告)号：WO2010065126A2
公开(公告)日：2010-06-10
申请号：PCT/US2009/006381
申请日：2009-12-04
申请人： AMS RESEARCH CORPORATION , CRANK, Justin M.
发明人： CRANK, Justin M.
IPC分类号： A61M5/20
CPC分类号： A61M5/1413 , A61M5/145 , A61M39/10 , A61M2005/14573 , A61M2039/0009 , A61M2205/502 , A61M2205/505 , A61M2209/045 , A61M2210/1078
摘要： An injection system including an injection chamber and an injectate reservoir that is removably attached to the injection chamber via an intermediate connector. The connector extends at a first end from the chamber and terminates at an opposite end with a fitting, such as a luer fitting, to which the injectate reservoir can be attached. The connector can be a relatively flexible component, such as a flexible tube, which is capable of absorbing the energy of an impact or other manipulation of the system to prevent or minimize the possibility of premature disconnection of the reservoir from the system.
摘要翻译：一种注射系统，其包括通过中间连接器可移除地附接到注射室的注射室和注射储存器。连接器在第一端处从腔室延伸并且在相对端处终止于诸如鲁尔配件的配件，注射器容器可以附接到该配件。连接器可以是相对柔性的组件，例如柔性管，其能够吸收系统的冲击或其他操纵的能量，以防止或最小化储存器从系统过早断开的可能性。

3. 发明申请

WO2010077271A2 METHOD AND APPARATUS FOR COMPENSATING FOR INJECTION MEDIA VISCOSITY IN A PRESSURIZED DRUG INJECTION SYSTEM 审中-公开
标题翻译：用于补偿注射药物注射系统中注射介质粘度的方法和设备
公开(公告)号：WO2010077271A2
公开(公告)日：2010-07-08
申请号：PCT/US2009/006383
申请日：2009-12-04
申请人： AMS RESEARCH CORPORATION , RYKHUS, Robert L. , CRANK, Justin M.
发明人： RYKHUS, Robert L. , CRANK, Justin M.
IPC分类号： A61M5/145 , A61M37/00
CPC分类号： A61M5/1452 , A61M31/00 , A61M37/00 , A61M2205/3341 , A61M2205/70
摘要： A needleless injection system is provided to deliver therapeutic fluids to an internal treatment site in a patient, where the system is pressurized and is capable of compensating for differences in injection media viscosity and mechanical system characteristics. In one aspect, a needleless therapeutic fluid injection system is provided that includes modular, interchangeable components. In particular, the system includes a console that generally includes the electronic and/or hydraulic control components for the system, an injection chamber, and a shaft or catheter tube.
摘要翻译：提供无针注射系统以将治疗流体输送到患者的内部治疗部位，其中系统被加压并且能够补偿注射介质粘度和机械系统特性的差异。在一个方面，提供了包括模块化的可互换部件的无针治疗性流体注射系统。特别地，该系统包括控制台，该控制台通常包括用于该系统的电子和/或液压控制部件，注射室以及轴或导管管。

4. 发明申请

WO2010065127A2 DEVICES, SYSTEMS AND METHODS FOR DELIVERING FLUID TO TISSUE 审中-公开
标题翻译：用于将流体输送到组织的装置，系统和方法
公开(公告)号：WO2010065127A2
公开(公告)日：2010-06-10
申请号：PCT/US2009/006382
申请日：2009-12-04
申请人： AMS RESEARCH CORPORATION , CRANK, Justin M. , HAUSCHILD, Sidney F.
发明人： CRANK, Justin M. , HAUSCHILD, Sidney F.
IPC分类号： A61M25/10 , A61M5/20 , A61M5/30
CPC分类号： A61M5/3007 , A61M5/204 , A61M5/30 , A61M5/31553 , A61M5/31581 , A61M5/425 , A61M25/10 , A61M25/1018 , A61M25/10182 , A61M25/10185 , A61M39/12 , A61M2005/3152 , A61M2210/1078
摘要： In one aspect of this invention, control systems are provided for controlling the inflation of a tissue tensioner or balloon for a fluid delivery system, such as for a needleless fluid injection device. In another aspect of the invention, a system for reducing the response time for jet injection of fluid is provided. In yet another aspect of the invention, systems and devices are provided for controlling the volume of fluid that is ejected from a fluid injection system, which systems include at least one stop that is selectively rotated to limit the movement of a shaft in a linear direction, thereby controlling the amount of fluid that is ejected from the system.
摘要翻译：在本发明的一个方面，提供控制系统用于控制用于流体输送系统的组织张紧器或气囊的膨胀，例如用于无针注射流体注射装置。在本发明的另一方面，提供了一种用于减少喷射流体的响应时间的系统。在本发明的另一方面，提供了用于控制从流体喷射系统喷射的流体体积的系统和装置，该系统包括至少一个选择性旋转的止挡件，以限制轴在直线方向上的运动从而控制从系统喷出的流体的量。

5. 发明申请

WO2011011372A2 NEEDLELESS INJECTION DEVICE COMPONENTS, SYSTEMS, AND METHODS 审中-公开
标题翻译：无针注射装置组件，系统和方法
公开(公告)号：WO2011011372A2
公开(公告)日：2011-01-27
申请号：PCT/US2010/042539
申请日：2010-07-20
申请人： AMS RESEARCH CORPORATION , RYKHUS, Robert L., Jr. , OGDAHL, Jason Westrum , CRANK, Justin M.
发明人： RYKHUS, Robert L., Jr. , OGDAHL, Jason Westrum , CRANK, Justin M.
IPC分类号： A61M5/30 , A61M31/00 , A61M29/02 , A61M25/10 , A61B1/00
CPC分类号： A61M25/0026 , A61B1/00087 , A61B1/0014 , A61B17/0218 , A61B2017/00296 , A61B2017/00557 , A61B2017/22069 , A61M5/30 , A61M25/007 , A61M25/10 , A61M25/1034 , A61M31/00 , A61M2025/1054 , A61M2025/1081 , A61M2210/1078
摘要： Described are needleless injection systems and methods that involve features including one or more of a tissue tensioner and a fitting that includes or attaches to a shaft, exemplary embodiments including: an elastic sleeve sized to fit under tension about the distal end of a flexible scope, such as an endoscope; a non-metal, polymeric tube-like device being optionally attached to the elastic sleeve for delivering a therapeutic fluid to a treatment site within a patient wherein the elastic sleeve may include an integral balloon (tissue tensioner) feature that can be used to position the injection orifice of the tube-like device proximate a treatment area.
摘要翻译：描述的是无针注射系统和方法，其涉及包括组织张紧器和包括或附接到轴的配件中的一个或多个的特征，示例性实施例包括：尺寸适于在柔性范围的远端附近张紧的弹性套筒，如内窥镜; 非金属的聚合物管状装置可选地附接到弹性套筒上，用于将治疗流体输送到患者内的治疗部位，其中弹性套筒可以包括整体气囊（组织张紧器）特征，其可用于将管状装置的注射孔靠近治疗区域。

6. 发明申请

WO2010074705A2 NEEDLELESS INJECTION DEVICE COMPONENTS, SYSTEMS, AND METHODS 审中-公开
标题翻译：无针注射装置组件，系统和方法
公开(公告)号：WO2010074705A2
公开(公告)日：2010-07-01
申请号：PCT/US2009/006384
申请日：2009-12-04
申请人： AMS RESEARCH CORPORATION , CRANK, Justin M.
发明人： CRANK, Justin M.
IPC分类号： A61M5/20 , A61M5/30 , A61M25/00 , A61M25/10
CPC分类号： A61M5/30 , A61M25/0069 , A61M25/1025
摘要： Described are needleless injection systems and methods that involve features including one or more of a tissue tensioner and a fitting for attaching to a distal end of a shaft, exemplary embodiments including: an elastic sleeve sized to fit under tension about the distal end of a flexible scope, such as an endoscope; a non-metal, polymeric tube-like device being optionally attached to the elastic sleeve for delivering a therapeutic fluid to a treatment site within a patient wherein the elastic sleeve may include an integral balloon (tissue tensioner) feature that can be used to position the injection orifice of the tube-like device proximate a treatment area.
摘要翻译：描述的是无针注射系统和方法，其涉及包括组织张紧器和用于附接到轴的远端的配件中的一个或多个的特征，示例性实施例包括：弹性套筒，其尺寸适于围绕柔性范围，如内窥镜; 非金属的聚合物管状装置可选地附接到弹性套筒上，用于将治疗流体输送到患者内的治疗部位，其中弹性套筒可以包括整体气囊（组织张紧器）特征，其可用于将管状装置的注射孔靠近治疗区域。

7. 发明申请

WO2010065133A2 DEVICES, SYSTEMS, AND RELATED METHODS FOR DELIVERY OF FLUID TO TISSUE 审中-公开
标题翻译：装置，系统和用于输送流体到组织的相关方法
公开(公告)号：WO2010065133A2
公开(公告)日：2010-06-10
申请号：PCT/US2009/006390
申请日：2009-12-04
申请人： AMS RESEARCH CORPORATION , CRANK, Justin M. , BERTELSON, Kathryn
发明人： CRANK, Justin M. , BERTELSON, Kathryn
IPC分类号： A61M5/20
CPC分类号： A61M5/30 , A61M5/3291 , A61M25/00 , A61M25/007 , A61M39/12 , A61M2039/1027 , A61M2210/1078 , A61M2210/1082 , A61M2210/1085 , A61M2210/1089
摘要： Described are devices useful to inject fluid to tissue without the use of a needle, and related methods; the devices include one or a combination of features such as ejection orifices, distal end control features, or combinations of these; the systems can include a fluid delivery system having an injector source and an access device; the access device can comprise a minimally invasive, tubular delivery lumen such as a catheter or endoscope; the tube-like device further includes one or more apposing jets that are selectively fired to force the injection orifice of the tube-like device against the target tissue; selective firing can include a continuous firing during the injection to improve the efficiency of the treatment.
摘要翻译：描述了可用于将液体注入组织而不使用针的装置及相关方法; 这些装置包括一个或诸如喷射孔，远端控制特征或它们的组合的特征的组合; 所述系统可以包括具有喷射源和进入装置的流体输送系统; 所述进入装置可以包括诸如导管或内窥镜的微创管状递送腔; 管状装置还包括一个或多个喷射装置，其被选择性地烧制以迫使管状装置的喷射孔抵靠靶组织; 选择性烧制可以包括在注射期间的连续烧制以提高治疗效率。

8. 发明申请

WO2012083176A2 HIGH-PRESSURE PNEUMATIC INJECTION SYSTEM AND METHOD 审中-公开
标题翻译：高压气动注射系统及方法
公开(公告)号：WO2012083176A2
公开(公告)日：2012-06-21
申请号：PCT/US2011/065510
申请日：2011-12-16
申请人： AMS RESEARCH CORPORATION , CRANK, Justin M.
发明人： CRANK, Justin M.
CPC分类号： A61M5/30 , A61B17/3203 , A61B17/3478 , A61B2017/22069 , A61M5/3015 , A61M25/007 , A61M25/04 , A61M25/1002 , A61M25/10184 , A61M37/00 , A61M2025/0681
摘要： A needleless or high-pressure injection system for injecting treatment or therapeutic fluid to tissue of the lower urinary tract, such as the prostate or bladder, is provided. The systems or devices can release the therapeutic fluid or "injectate" at high-pressure out of one or more orifices at the end of an elongate shaft inserted into the urethra. Various embodiments can include a pneumatic or fully-pneumatic system adapted to selectively release the high-pressure injectate, while also providing firing or triggering protection.
摘要翻译：提供了用于将治疗或治疗流体注射到下尿路组织例如前列腺或膀胱的无针或高压注射系统。这些系统或装置可以在插入尿道的细长轴的端部处从一个或多个孔中的高压释放治疗流体或“注射”。各种实施例可以包括适于选择性地释放高压注射器的气动或全气动系统，同时还提供击发或触发保护。

9. 发明申请

WO2011011382A1 DEVICES, SYSTEMS, AND RELATED METHODS FOR DELIVERY OF FLUID TO TISSUE 审中-公开
标题翻译：用于将流体输送到组织的装置，系统和相关方法
公开(公告)号：WO2011011382A1
公开(公告)日：2011-01-27
申请号：PCT/US2010/042554
申请日：2010-07-20
申请人： AMS RESEARCH CORPORATION , CRANK, Justin M.
发明人： CRANK, Justin M.
IPC分类号： A61M25/00
CPC分类号： A61M25/007 , A61M25/04 , A61M25/10
摘要： Described are devices useful to inject fluid to tissue without the use of a needle, and related methods; the devices include one or a combination of features such as ejection orifices, distal end control features, or combinations of these; the systems can include a fluid delivery system having an injector source and an access device; the access device can comprise a minimally invasive, tubular delivery lumen such as a catheter or endoscope; the tube-like device further includes one or more apposing jets that are selectively fired to force the injection orifice of the tube-like device against the target tissue; selective firing can include a continuous firing during the injection to improve the efficiency of the treatment.
摘要翻译：描述了用于在不使用针的情况下将流体注射到组织的装置，以及相关方法; 该装置包括一个或多个特征的组合，例如喷射孔，远端控制特征或这些的组合; 该系统可以包括具有注射器源和进入装置的流体输送系统; 进入装置可以包括微创的管状输送腔，例如导管或内窥镜; 管状装置还包括一个或多个合成喷嘴，所述合成喷嘴被选择性地发射以迫使管状装置的注射孔靠着目标组织; 选择性烧制可以包括注射期间的连续烧制，以提高治疗效率。

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