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1. 发明申请

WO2012061017A1 FIBROUS CONTAINMENT FOR HEMOSTASIS PLUG 审中-公开
标题翻译：用于HEMOSTASIS PLUG的FIBROUS容纳
公开(公告)号：WO2012061017A1
公开(公告)日：2012-05-10
申请号：PCT/US2011/056857
申请日：2011-10-19
申请人： BOSTON SCIENTIFIC SCIMED, INC. , JENSON, Mark L. , HILL, Jason P. , FENG, James Q. , SOGARD, David J. , WARNER, Robert W. , HAVERKOST, Patrick A
发明人： JENSON, Mark L. , HILL, Jason P. , FENG, James Q. , SOGARD, David J. , WARNER, Robert W. , HAVERKOST, Patrick A
IPC分类号： A61B17/00 , A61B17/06
CPC分类号： A61B17/0057 , A61B2017/00637 , A61B2017/00654 , A61B2017/00659 , A61B2017/0404 , A61B2017/0417 , A61B2017/06185
摘要： A device for sealing an opening in a vessel includes an anchor (20) attached to a suture (30). The anchor is inserted through the opening into the vessel, and the suture pulls the anchor against the vessel wall, forming a seal. A plug (40) is inserted over the suture and is axially compressed toward the anchor, locking the elements in place. The suture is braided or woven outside of the anchor so that it may be stored and handled easily, and is unbraided, unwoven and/or untangled at its distal end inside the anchor, so that individual filaments within the suture may extend laterally within the anchor. The laterally extending filaments subtend a larger footprint within the anchor than a comparable footprint if the suture were to remain braided or tied into a knot within the anchor, which may more effectively distribute the retaining forces within the anchor. In some cases, the plug material is formed from fibers of a mechanically strong material blended into a quick-dissolving material.
摘要翻译：用于密封容器中的开口的装置包括附接到缝合线（30）的锚固件（20）。锚固件通过开口插入容器中，并且缝合线将锚固件拉靠在血管壁上，形成密封。塞子（40）插入缝合线上并朝向锚固件轴向压缩，将元件锁定就位。该缝合线被编织或编织在锚定体之外，使得其可以容易地储存和处理，并且在其锚固体内部的远端处是未被覆盖的，无纺的和/或解开的，使得缝合线内的单个细丝可以在锚定件内横向延伸。横向延伸的长丝在锚固体内对着较大的覆盖区域，而不是如果缝合线保持编织或连接到锚固体内的结，这可以更有效地将锚定力分配在锚固体内。在一些情况下，插塞材料由掺入快速溶解材料的机械强度材料的纤维形成。

2. 发明申请

WO2010003003A1 IMPLANTS INCLUDING FRACTAL STRUCTURES 审中-公开
标题翻译：包括断裂结构的植入物
公开(公告)号：WO2010003003A1
公开(公告)日：2010-01-07
申请号：PCT/US2009/049422
申请日：2009-07-01
申请人： BOSTON SCIENTIFIC SCIMED, INC. , ATANASOSKA, Liliana , HOLMAN, Tom , FENG, James Q. , WARNER, Robert W. , ALI, Afsar
发明人： ATANASOSKA, Liliana , HOLMAN, Tom , FENG, James Q. , WARNER, Robert W. , ALI, Afsar
IPC分类号： A61F2/86
CPC分类号： A61F2/86 , A61F2/0077
摘要： An endoprosthesis includes a member having a surface that includes a fractal structure.
摘要翻译：内假体包括具有包括分形结构的表面的构件。

3. 发明申请

WO2012149328A1 PROTECTIVE SURFACES FOR DRUG-COATED MEDICAL DEVICES 审中-公开
标题翻译：药物涂层医疗器械的保护表面
公开(公告)号：WO2012149328A1
公开(公告)日：2012-11-01
申请号：PCT/US2012/035466
申请日：2012-04-27
申请人： BOSTON SCIENTIFIC SCIMED, INC. , WEBER, Jan , FENG, James Q.
发明人： WEBER, Jan , FENG, James Q.
IPC分类号： A61M25/10 , A61F2/82
CPC分类号： A61M25/104 , A61F2/958 , A61F2002/9583 , A61F2250/0067 , A61M25/1002 , A61M2025/0681 , A61M2025/1004 , A61M2025/105 , A61M2025/1081 , A61M2025/1086 , Y10T156/1051
摘要： Medical balloons (14) having one or more folds (16), on which are disposed protective surfaces (11,13) e.g. protective lines or strips and at least one therapeutic agent (15,17) between the lines. The protective surfaces prevent, inhibit, or reduce the contact between therapeutic agent on one area, e.g., a surface area, and an opposing area or therapeutic agent on the opposing area when the balloon is folded, relative to the contact that would occur in the absence of protective surfaces. The protective surfaces also prevent, inhibit, or reduce loss of therapeutic agent from the balloon surface as a result of, for example, contact with a medical device during expansion or removal of a protective sheath. Also a medical device delivery system comprising a medical device surrounded by a retractable sheath (22,41), wherein protective surfaces, e.g. lines are disposed on the sheath such that, during retraction of the sheath, the protective surfaces (27,43) on the moving part of the sheath slide against the protective surfaces on the stationary part of the sheath, resulting in less friction than would be produced in the absence of the protective surfaces.
摘要翻译：具有一个或多个折叠（16）的医用气囊（14），其上设置有保护表面（11,13），例如。保护线或条和线之间的至少一种治疗剂（15,17）。当球囊被折叠时，保护表面防止，抑制或减少一个区域上的治疗剂（例如表面区域）和相对区域上的相对区域或治疗剂之间的接触，相对于在没有保护表面。由于例如在膨胀或移除保护性护套期间与医疗装置的接触，保护表面也防止，抑制或减少治疗剂从球囊表面的损失。还包括医疗装置输送系统，其包括由可缩回护套（22,41）包围的医疗装置，其中保护表面管线设置在护套上，使得在套管回缩期间，护套的移动部分上的保护表面（27,43）抵靠护套的固定部分上的保护表面滑动，导致较少的摩擦在没有保护表面的情况下产生。

4. 发明申请

WO2008083069A2 BIOERODIBLE NANO-FIBROUS AND NANO-POROUS CONDUCTIVE COMPOSITES 审中-公开
标题翻译：可生物降解的纳米纤维和纳米多孔导电复合材料
公开(公告)号：WO2008083069A2
公开(公告)日：2008-07-10
申请号：PCT/US2007/088533
申请日：2007-12-21
申请人： BOSTON SCIENTIFIC SCIMED, INC. , ATANASOSKA, Liliana , FENG, James Q. , WEBER, Jan , SHIPPY III, James Lee
发明人： ATANASOSKA, Liliana , FENG, James Q. , WEBER, Jan , SHIPPY III, James Lee
IPC分类号： A61L27/44 , A61L27/50 , A61L27/54 , A61L27/58 , A61L29/12 , A61L29/14 , A61L29/16 , A61L31/12 , A61L31/14 , A61L31/16
CPC分类号： A61L27/40 , A61L27/14 , A61L27/50 , A61L27/58 , A61L2400/12
摘要： A bioerodible conductive tissue scaffold that can provide, e.g., improved tissue growth.
摘要翻译：可以提供例如改善的组织生长的生物蚀蚀性导电组织支架。

5. 发明申请

WO2011119430A1 ENDOPROSTHESIS 审中-公开
标题翻译：内置假体
公开(公告)号：WO2011119430A1
公开(公告)日：2011-09-29
申请号：PCT/US2011/029005
申请日：2011-03-18
申请人： BOSTON SCIENTIFIC SCIMED, INC. , ATANASOSKA, Liliana , KOSTREWA, Angela , CAMBRONNE, Matthew , FENG, James Q. , RADHAKRISHNAN, Rajesh
发明人： ATANASOSKA, Liliana , KOSTREWA, Angela , CAMBRONNE, Matthew , FENG, James Q. , RADHAKRISHNAN, Rajesh
IPC分类号： A61L31/08 , A61L31/14
CPC分类号： A61L31/022 , A61L31/06 , A61L31/088 , A61L31/10 , A61L31/148 , A61L31/16 , Y10T29/49982 , C08L67/04
摘要： Endoprostheses and methods of making endoprostheses are disclosed. For example, endoprostheses are described that include an endoprosthesis body, a biodegradable metallic tie layer, and a polymer coating about the endoprosthesis body. The biodegradable tie layer and the polymer coating can have a high peel strength from the body.
摘要翻译：公开内裤假体和内用假体的方法。例如，描述了内括约肌体，其包括内置假体，可生物降解的金属粘结层和围绕内假体的聚合物涂层。可生物降解的粘结层和聚合物涂层可以具有来自身体的高剥离强度。

6. 发明申请

WO2010101901A2 SELF-BUFFERING MEDICAL IMPLANTS 审中-公开
标题翻译：自助医疗植入物
公开(公告)号：WO2010101901A2
公开(公告)日：2010-09-10
申请号：PCT/US2010/025896
申请日：2010-03-02
申请人： BOSTON SCIENTIFIC SCIMED, INC. , ATANASOSKA, Liliana , SHIPPY, James, Lee, III , HOLMAN, Tom , ARNEY, Michael, S. , SCHOENLE, Victor , GENOVESE, Frank , FENG, James Q. , FLANAGAN, Aiden , WEBER, Jan
发明人： ATANASOSKA, Liliana , SHIPPY, James, Lee, III , HOLMAN, Tom , ARNEY, Michael, S. , SCHOENLE, Victor , GENOVESE, Frank , FENG, James Q. , FLANAGAN, Aiden , WEBER, Jan
IPC分类号： A61L27/04
CPC分类号： A61L31/148 , A61L27/34 , A61L27/446 , A61L27/54 , A61L27/58 , A61L31/10 , A61L31/128 , A61L31/16 , A61L2300/416 , A61L2300/604 , A61L2400/12 , A61L2420/04 , C08L67/04
摘要： A medical implant includes a bioerodible portion that includes a bioerodible polymer and a bioerodible metal. The bioerodible polymer matrix degrades under physiological conditions to form acidic degradation products. The bioerodible metal degrades under physiological conditions to form basic degradation products. The acidic degradation products and the basic degradation products buffer at least a portion of the medical implant. In one aspect, the bioerodible portion includes a bioerodible polymer matrix and a bioerodible metal within the bioerodible polymer matrix. In another aspect, the medical implant can include a body, a plurality of discrete deposits of the bioerodible polymer on the body, and a plurality of discrete deposits of the bioerodible metal on the body.
摘要翻译：医疗植入物包括生物腐蚀性部分，其包括生物可蚀解聚合物和生物腐蚀性金属。生物可蚀解聚合物基质在生理条件下降解形成酸性降解产物。生物腐蚀金属在生理条件下降解形成碱性降解产物。酸性降解产物和碱性降解产物缓冲至少一部分医用植入物。在一个方面，生物可蚀解部分包括生物可腐蚀聚合物基质和生物可腐蚀的聚合物基质内的生物可腐蚀金属。在另一方面，医疗植入物可以包括主体，身体上的生物可蚀解聚合物的多个离散沉积物，以及身体上的生物可腐蚀金属的多个离散沉积物。

7. 发明申请

WO2014011888A1 LOW PROFILE HEART VALVE DELIVERY SYSTEM AND METHOD 审中-公开
标题翻译：低剖面心瓣输送系统及方法
公开(公告)号：WO2014011888A1
公开(公告)日：2014-01-16
申请号：PCT/US2013/050087
申请日：2013-07-11
申请人： BOSTON SCIENTIFIC SCIMED, INC.
发明人： ZHOU, Pu , WANG, Huisun , FENG, James Q.
IPC分类号： A61F2/966 , A61F2/24
CPC分类号： A61F2/2436 , A61F2/2418 , A61F2/2427 , A61F2/966 , A61F2210/0004 , A61F2220/0075
摘要： A heart valve delivery system includes a low-profile catheter having an outer sheath, the outer sheath having therein a stent and a replacement heart valve. In an unemployed configuration, the stent is located distally to the replacement heart valve. Upon deployment, however, the stent and replacement heart valve are expanded and the replacement heart valve is situated within the stent.
摘要翻译：心脏瓣膜输送系统包括具有外护套的低轮廓导管，外护套在其中具有支架和置换心脏瓣膜。在失业的配置中，支架位于替换心脏瓣膜的远端。然而，部署后，支架和置换心脏瓣膜扩张，置换心脏瓣膜位于支架内。

8. 发明授权

EP2632342B1 FIBROUS CONTAINMENT FOR HEMOSTASIS PLUG 有权
标题翻译： HEMOSTASIS插头的纤维内胆
公开(公告)号：EP2632342B1
公开(公告)日：2016-10-05
申请号：EP11782273.4
申请日：2011-10-19
申请人： Boston Scientific Scimed, Inc.
发明人： JENSON, Mark L. , HILL, Jason P. , FENG, James Q. , SOGARD, David J. , WARNER, Robert W. , HAVERKOST, Patrick A.
IPC分类号： A61B17/00 , A61B17/06 , A61B17/04
CPC分类号： A61B17/0057 , A61B2017/00637 , A61B2017/00654 , A61B2017/00659 , A61B2017/0404 , A61B2017/0417 , A61B2017/06185

9. 发明授权

EP2872077B1 LOW PROFILE HEART VALVE DELIVERY SYSTEM 有权
标题翻译：低剖面心脏瓣膜输送系统
公开(公告)号：EP2872077B1
公开(公告)日：2017-10-04
申请号：EP13740159.2
申请日：2013-07-11
申请人： Boston Scientific Scimed, Inc.
发明人： ZHOU, Pu , WANG, Huisun , FENG, James Q.
IPC分类号： A61F2/966 , A61F2/24
CPC分类号： A61F2/2436 , A61F2/2418 , A61F2/2427 , A61F2/966 , A61F2210/0004 , A61F2220/0075
摘要： A heart valve delivery system includes a low-profile catheter having an outer sheath, the outer sheath having therein a stent and a replacement heart valve. In an unemployed configuration, the stent is located distally to the replacement heart valve. Upon deployment, however, the stent and replacement heart valve are expanded and the replacement heart valve is situated within the stent.
摘要翻译：心脏瓣膜输送系统包括具有外部护套的低轮廓导管，外部护套中具有支架和置换心脏瓣膜。在失业状态下，支架位于置换心脏瓣膜的远端。然而，在部署时，支架和置换心脏瓣膜扩张并且置换心脏瓣膜位于支架内。

10. 发明公开

EP2872077A1 LOW PROFILE HEART VALVE DELIVERY SYSTEM AND METHOD 有权
标题翻译： VERABREICHUNGSSYSTEMFÜREINE HERZKLAPPE MIT NIEDRIGEM PROFIL
公开(公告)号：EP2872077A1
公开(公告)日：2015-05-20
申请号：EP13740159.2
申请日：2013-07-11
申请人： Boston Scientific Scimed, Inc.
发明人： ZHOU, Pu , WANG, Huisun , FENG, James Q.
IPC分类号： A61F2/966 , A61F2/24
CPC分类号： A61F2/2436 , A61F2/2418 , A61F2/2427 , A61F2/966 , A61F2210/0004 , A61F2220/0075
摘要： A heart valve delivery system includes a low-profile catheter having an outer sheath, the outer sheath having therein a stent and a replacement heart valve. In an unemployed configuration, the stent is located distally to the replacement heart valve. Upon deployment, however, the stent and replacement heart valve are expanded and the replacement heart valve is situated within the stent.
摘要翻译：心脏瓣膜输送系统包括具有外护套的低轮廓导管，外护套具有支架和置换心脏瓣膜。在失业的配置中，支架位于替换心脏瓣膜的远端。然而，在部署时，支架和置换心脏瓣膜扩张，置换心脏瓣膜位于支架内。

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