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1. 发明申请

WO2009085206A3 PERCUTANEOUS HEART VALVE, SYSTEM, AND METHOD 审中-公开
公开(公告)号：WO2009085206A3
公开(公告)日：2009-07-09
申请号：PCT/US2008/013888
申请日：2008-12-19
申请人： BOSTON SCIENTIFIC SCIMED, INC. , KVEEN, Graig, L. , JENSON, Mark, L. , THIELEN, Joseph, M. , DRASLER, William, J. , EIDENSCHINK, Tracee, E.J.
发明人： KVEEN, Graig, L. , JENSON, Mark, L. , THIELEN, Joseph, M. , DRASLER, William, J. , EIDENSCHINK, Tracee, E.J.
IPC分类号： A61F2/24
摘要： Devices, systems, and methods are provided to treat diseased cardiac valves. The device includes a percutaneous heart valve (100) having an expandable valve frame (102) including valve frame members (105), a valve leaflet (132) coupled to the valve frame, and an expandable stent anchoring frame (104) coupled to the valve frame including stent frame members (106) defining a first portion (108) and a second portion (110) having greater flexibility than the first portion, where the first portion and the valve frame define a length, and where the stent frame members and the valve frame members along the length provide a contiguous surface over which a delivery device can repeatedly slide over the length in its entirety in two longitudinal directions when the first portion and the valve frame are in a partially expanded state during delivery from the delivery device.

2. 发明申请

WO2008097967A2 SELF-ORIENTATING SUTURE WOUND CLOSURE DEVICE 审中-公开
标题翻译：自立式闭合闭合装置
公开(公告)号：WO2008097967A2
公开(公告)日：2008-08-14
申请号：PCT/US2008/053046
申请日：2008-02-05
申请人： BOSTON SCIENTIFIC SCIMED, INC. , DRASLER, William, J. , EIDENSCHINK, Tracee , THIELEN, Joeseph, M. , JENSON, Mark, L. , SADISIVA, Anu
发明人： DRASLER, William, J. , EIDENSCHINK, Tracee , THIELEN, Joeseph, M. , JENSON, Mark, L. , SADISIVA, Anu
IPC分类号： A61B17/00 , A61B17/34 , A61B19/00
CPC分类号： A61B17/0057 , A61B17/0469 , A61B2017/00641 , A61B2017/00663 , A61B2017/00867 , A61B2017/047 , A61B2017/0472 , A61B2017/3484 , A61B2090/067 , A61B2090/0811
摘要： A device is disclosed foi providing an indication as to the relative position of a vessel or aiteiy opening thereby facilitating the choice of which suturing or plugging technique to thereafter use. A disclosed device includes an outei tube and a collapsible foot slidably disposed within a distal end of the outei tube The foot is connected to a shaft that passes through the tube and exits a proximal end thereof The device may further include one or more threaded suture needles, a biodegradable plug or1 other wound closing device that is connected to another shaft The collapsed or1 folded foot is pushed distally out of the tube and through the opening in the vessel whereupon the foot expands Pulling the expanded foot in the proximal direction provides an indication as to the orientation of the opening in the vessel, which assists in determining the type of closing procedure to be carried out The shaft connected to the foot is preferably connected to an indicator that indicates to the operator or physician that the vessel opening is in one of three positions on the vessel - left, top or right As an alternative, the indicator bar may indicate a relative position in degrees, mm ot μm in deviation from a top stick (or1 top position)
摘要翻译：公开了一种提供关于容器的相对位置或有利开口的指示的装置，从而便于选择其后使用哪种缝合或堵塞技术。所公开的装置包括外壳管和可滑动地设置在外管的远端内的可折叠的脚。脚连接到穿过管并离开其近端的轴。该装置还可包括一个或多个螺纹缝合针，可生物降解的塞子或其他伤口闭合装置，其连接到另一个轴。折叠的或折叠的脚被向远侧推出管并通过容器中的开口，由此足部膨胀。沿近侧方向拉伸扩张的脚，提供指示有助于确定要执行的关闭程序的类型。连接到脚的轴优选地连接到指示器，该指示器向操作者或医师指示血管开口处于船上的三个位置 - 左侧，右侧或右侧。另外，指示杆可能表示相对位置，以mm为单位偏离顶杆（或顶部位置）

3. 发明申请

WO2008076895A1 STROKE INTERVENTION APPARATUS 审中-公开
公开(公告)号：WO2008076895A1
公开(公告)日：2008-06-26
申请号：PCT/US2007/087599
申请日：2007-12-14
申请人： BOSTON SCIENTIFIC SCIMED, INC. , JENSON, Mark, L. , DRASLER, William, J. , GILL, Jagjit
发明人： JENSON, Mark, L. , DRASLER, William, J. , GILL, Jagjit
IPC分类号： A61B5/03 , A61M27/00 , A61M25/00 , A61M25/10
CPC分类号： A61B5/03 , A61M25/003 , A61M25/0032 , A61M2025/0002 , A61M2025/1052
摘要： Disclosed herein is an intrathecal catheter (102) having a lumen (112) adapted to transfer liquid between the proximal end of the catheter and its distal end; a pressure detector (116); and a first sealer (120), adapted to seal the catheter against a tissue. Also disclosed herein is a stroke intervention system comprising an intrathecal catheter, an infusate supply chamber (206) in fluid communication with the catheter; a pump (204) in fluid communication with the catheter; and a pressure gauge in fluid cqmmunication with the pressure detector (116).
摘要翻译：本文公开了一种鞘内导管（102），其具有适于在导管的近端和其远端之间转移液体的内腔（112）压力检测器（116）; 以及适于将导管密封在组织上的第一密封件（120）。本文还公开了包括鞘内导管，与导管流体连通的输注供应室（206）的中风干预系统; 与所述导管流体连通的泵（204）; 以及压力计与压力检测器（116）的流体隔离。

4. 发明申请

WO2006031469A1 CARDIAC VALVE, SYSTEM, AND METHOD 审中-公开
标题翻译：心脏瓣膜，系统和方法
公开(公告)号：WO2006031469A1
公开(公告)日：2006-03-23
申请号：PCT/US2005/031329
申请日：2005-09-02
申请人： BOSTON SCIENTIFIC SCIMED, INC. , JENSON, Mark, L. , DRASLER, William, J. , LAFONTAINE, Daniel, M.
发明人： JENSON, Mark, L. , DRASLER, William, J. , LAFONTAINE, Daniel, M.
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2412 , A61F2230/008
摘要： A cardiac valve with a support frame having a first end member and a second end member opposing the first end member in a substantially fixed distance relationship, and a cover extending over the support frame to allow for unidirectional flow of a liquid through the valve.
摘要翻译：具有支撑框架的心脏瓣膜具有第一端构件和与所述第一端构件基本上固定的距离关系相对的第二端构件，以及在所述支撑框架上延伸以允许液体通过所述瓣膜的单向流动的盖。

5. 发明申请

WO2006011969A1 MYOCARDIAL TREATMENT APPARATUS AND METHOD OF TREATMENT 审中-公开
标题翻译：心肌治疗装置和治疗方法
公开(公告)号：WO2006011969A1
公开(公告)日：2006-02-02
申请号：PCT/US2005/020605
申请日：2005-06-10
申请人： BOSTON SCIENTIFIC SCIMED, INC. , JENSON, Mark, L. , DRASLER, William, J.
发明人： JENSON, Mark, L. , DRASLER, William, J.
IPC分类号： A61F2/06 , A61B17/11
CPC分类号： A61B17/320016 , A61B2017/00243 , A61F2/064 , A61F2/2493
摘要： Apparatus and methods for forming a conduit through an infarcted region where the conduit is in fluid communication with a supply of oxygenated blood and the venous vasculature and flowing oxygenated blood from the supply of oxygenated blood through the conduit and to the venous vasculature.
摘要翻译：用于通过梗塞区域形成导管的装置和方法，其中所述导管与氧合血液供应和所述静脉血管和来自所述供血的氧合血液通过所述导管和所述静脉血管的流动的氧合血液流体连通。

6. 发明申请

WO2008121632A2 EMBOLIC CAPTURING DEVICES AND METHODS 审中-公开
标题翻译：嵌入式捕获装置和方法
公开(公告)号：WO2008121632A2
公开(公告)日：2008-10-09
申请号：PCT/US2008/058177
申请日：2008-03-26
申请人： BOSTON SCIENTIFIC SCIMED, INC. , JENSON, Mark, L. , DRASLER, William, J.
发明人： JENSON, Mark, L. , DRASLER, William, J.
IPC分类号： A61B17/22
CPC分类号： A61B17/221 , A61B2017/22082 , A61B2017/2212 , A61B2017/2946 , A61B2090/0811
摘要： Disclosed is an emboli capturing device having a first support hoop at a distal portion of a first elongate member, and a support member that is coupled to the first support hoop. The support member can comprise a second elongate member. In some cases, the second elongate member can be coupled to the first support hoop. In other cases, the support member can comprise a second elongate member and a support strut. The support strut can be coupled to both the first support hoop and the second elongate member. Movement of the support member relative to the first elongate member can translate the first support hoop between collapsed and expanded configurations. Once in a desired configuration, the support members can also provide support to maintain the first support hoop in the desired configuration. Also disclosed is a combination emboli capturing and perfusion device. The combination device can have a perfusion member in combination with an emboli capturing device. The perfusion member can facilitate the introduction of fluids around a lesion in a vessel of a patient, for example if the lesion is creating a partial or total occlusion of the vessel.
摘要翻译：公开了一种栓塞捕获装置，其在第一细长构件的远端部分具有第一支撑环，以及联接到第一支撑环的支撑构件。支撑构件可以包括第二细长构件。在一些情况下，第二细长构件可以联接到第一支撑环。在其他情况下，支撑构件可以包括第二细长构件和支撑支柱。支撑支柱可以联接到第一支撑环和第二细长构件。支撑构件相对于第一细长构件的运动可以在折叠和膨胀构型之间平移第一支撑箍。一旦处于期望的构造，支撑构件还可以提供支撑以将第一支撑环保持在期望的构造。还公开了组合栓塞和灌注装置。组合装置可以具有与栓塞捕获装置组合的灌注构件。灌注构件可以促进在患者的血管中的病变周围引入流体，例如，如果病变产生血管的部分或完全闭塞。

7. 发明申请

WO2008097956A1 VASCULAR SEALING DEVICE AND METHOD USING CLOT ENHANCING BALLOON AND ELECTRIC FIELD GENERATION 审中-公开
标题翻译：油封密封装置和使用加强气球和电场产生的方法
公开(公告)号：WO2008097956A1
公开(公告)日：2008-08-14
申请号：PCT/US2008/053034
申请日：2008-02-05
申请人： BOSTON SCIENTIFIC SCIMED, INC. , DRASLER, William, J. , EIDENSCHINK, Tracee , THIELEN, Joeseph, M. , JENSON, Mark, L. , SADISIVA, Anu
发明人： DRASLER, William, J. , EIDENSCHINK, Tracee , THIELEN, Joeseph, M. , JENSON, Mark, L. , SADISIVA, Anu
IPC分类号： A61B17/00 , A61B18/00
CPC分类号： A61B18/14 , A61B17/0057 , A61B2017/00654 , A61N1/18 , A61N1/32
摘要： An apparatus and method for closing an opening in a blood vessel wall is disclosed. The apparatus includes at least one member which is extended through a tissue tract formed though the epidermis and subcutaneous layer of skin and through the opening in the blood vessel. The member includes a proximal end and a distal end with the distal end being positionable proximate to the opening in the blood vessel wall. A positive electrode is positioned next to the distal end with a negative electrode being positioned next to the proximal end When the electrodes are energized an electric field is created therebetween, blood cells are attracted to the positive electrode, and a thrombus is formed at the opening in the blood vessel wall. The member may include a balloon at the distal end to temporarily occlude blood flow from the blood vessel to the tissue tract to facilitate formation of the thrombus. In addition, the shape of the balloon may be tailored to facilitate the formation of the thrombus including, but not limited to, the creation of pockets and self-supporting balloons.
摘要翻译：公开了一种用于封闭血管壁中的开口的装置和方法。该装置包括至少一个构件，其延伸穿过通过皮肤的表皮和皮下层形成并通过血管中的开口形成的组织通道。该构件包括近端和远端，远端可靠近血管壁中的开口定位。正电极位于远端附近，负极位于近端的旁边。当电极通电时，电极之间产生电场，血细胞被吸引到正电极，并且在开口处形成血栓在血管壁。该构件可以包括在远端处的气囊，以暂时阻断从血管到组织道的血流，以促进血栓的形成。此外，气囊的形状可以被调整以促进血栓的形成，包括但不限于口袋和自支撑气囊的产生。

8. 发明申请

WO2008097955A1 APPARATUS AND METHOD FOR CLOSING AN OPENING IN A BLOOD VESSEL USING A PERMANENT IMPLANT 审中-公开
标题翻译：使用永久植入物在血管中闭合开放装置和方法
公开(公告)号：WO2008097955A1
公开(公告)日：2008-08-14
申请号：PCT/US2008/053033
申请日：2008-02-05
申请人： BOSTON SCIENTIFIC SCIMED, INC. , DRASLER, William, J. , EIDENSCHINK, Tracee , THIELEN, Joeseph, M. , JENSON, Mark, L. , SADISIVA, Anu
发明人： DRASLER, William, J. , EIDENSCHINK, Tracee , THIELEN, Joeseph, M. , JENSON, Mark, L. , SADISIVA, Anu
IPC分类号： A61B17/00
CPC分类号： A61B17/0057 , A61B2017/00004 , A61B2017/00654 , A61B2017/00659 , A61B2017/0069 , A61B2017/00862 , A61B2017/00867 , A61B2017/00884
摘要： An apparatus (28) and method for closing an arteriotomy site (20) is disclosed The apparatus includes inner (32) and outer flames (34) adapted to sandwich a blood vessel wall (26) therebetween. The inner and outer frames may be manufactured from memory metals such that they can be compressed during the insertion into the tissue tract proximate the arteriotomy site, and then deployed into an expanded configuration larger than the dimensions of the arteriotomy opening itself. A universal joint (36) connects the inner and outer frames to ensure proper pivoting therebetween. In addition, polymeric coverings (54) can be provided on the inner and outer frames to ensure closure, while a collagen plug (52) can also be provided between inner and outer frames to facilitate closure as well.
摘要翻译：公开了一种用于闭合动脉切开术部位（20）的装置（28）和方法。该装置包括适于将血管壁（26）夹在其间的内部（32）和外部火焰（34）。内框架和外框架可以由记忆金属制成，使得它们可以在插入到接近动脉切开部位的组织道中被压缩，然后展开成比动脉切开术本身的尺寸更大的扩张构型。万向接头（36）连接内框架和外框架，以确保其间的正确枢转。此外，聚合物覆盖物（54）可以设置在内框架和外框架上以确保封闭，而也可以在内框架和外框架之间提供胶原塞（52）以便于封闭。

9. 发明申请

WO2007095498A1 APPARATUS AND METHOD FOR TREATING OCCLUDED VASCULATURE 审中-公开
标题翻译：用于治疗闭塞性血管的装置和方法
公开(公告)号：WO2007095498A1
公开(公告)日：2007-08-23
申请号：PCT/US2007/061995
申请日：2007-02-12
申请人： BOSTON SCIENTIFIC SCIMED, INC. , JENSON, Mark, L. , DRASLER, William, J.
发明人： JENSON, Mark, L. , DRASLER, William, J.
IPC分类号： A61B17/22 , A61M25/00 , A61M25/09
CPC分类号： A61B17/3207 , A61B2017/00398 , A61B2017/22044 , A61B2017/22077 , A61B2017/22094 , A61M25/0084 , A61M25/0138 , A61M2025/0046 , A61M2025/0063 , A61M2025/1093
摘要： Occluded vasculature (284) such as occluded arterial vasculature can be recanalized using a device (10) that is configured to penetrate an occlusion while limiting a distance that said penetration structure can extend in orde to limit inadvertent vascular damage. The device can include an elongate sha (12) of a guidewire and a stylet (32) disposed within a lumen of the elongat shaft (20) such that the stylet is selectively actuatable within the elongat shaft .
摘要翻译：封闭的脉管系统（284）例如闭塞的动脉血管可以使用被配置为穿透闭塞同时限制所述穿透结构可延伸到远处以限制无意的血管损伤的距离的装置（10）再通。该装置可以包括导丝的细长沙（12）和设置在伸长轴（20）的内腔内的探针（32），使得探针可在伸长轴内选择性地致动。

10. 发明申请

WO2006011970A1 APPARATUS FOR TREATING OCCLUDED VASCULATURE 审中-公开
标题翻译：用于治疗闭塞性血管的装置
公开(公告)号：WO2006011970A1
公开(公告)日：2006-02-02
申请号：PCT/US2005/020606
申请日：2005-06-10
申请人： BOSTON SCIENTIFIC SCIMED, INC. , JENSON, Mark, L. , DRASLER, William, J. , LAFONTAINE, Daniel, M.
发明人： JENSON, Mark, L. , DRASLER, William, J. , LAFONTAINE, Daniel, M.
IPC分类号： A61B17/22
CPC分类号： A61B17/3207 , A61B2017/00398 , A61B2017/22044 , A61B2017/22077
摘要： Occluded vasculature such as occluded arterial vasculature can be recanalized using a device that is configured to penetrate an occlusion, while limiting a distance that said penetration structure can extend in order to limit inadvertent vascular damage. The device can include an elongate sheath (106) and a stylet (118) disposed within the elongate sheath. The elongate sheath and the stylet can include, in combination, an engagement section (128) that is configured to limit relative axial movement between the elongate sheath (106) and the stylet (118).
摘要翻译：封闭的脉管系统如闭塞的动脉脉管系统可以使用被配置为穿透闭塞的装置再次通气，同时限制所述穿透结构可以延伸的距离，以限制无意的血管损伤。该装置可以包括细长护套（106）和设置在细长护套内的探针（118）。细长护套和探针可组合地包括配合部分（128），其配置成限制细长护套（106）和探针（118）之间的相对轴向运动。

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